Oxaliplatin_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Oxaliplatin perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Oxaliplatin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FNDC3B fibronectin type III domain containing 3B 0.139823
SMAD3 SMAD family member 3 0.103602
MACF1 microtubule-actin crosslinking factor 1 0.0987628
DST dystonin 0.0868875
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0834532
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0798257
LOC112694756 uncharaterized LOC112694756 0.0694215
LDHA lactate dehydrogenase A 0.0683747
INTS6 integrator complex subunit 6 0.067966
TRIO trio Rho guanine nucleotide exchange factor 0.0656192
MYH9 myosin, heavy chain 9, non-muscle 0.0639181
HMGA2 high mobility group AT-hook 2 0.0585421
NIBAN2 niban apoptosis regulator 2 0.0573663
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0519799
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0518895
CD44 CD44 molecule (Indian blood group) 0.0514892
PLEC plectin 0.0507782
ATXN1 ataxin 1 0.0497714
FLNA filamin A, alpha 0.0493964
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0487333
CEP250 centrosomal protein 250kDa 0.0480724
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0480297
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0469307
SVIL supervillin 0.0468386
AHNAK2 AHNAK nucleoprotein 2 0.0467868
NT5E 5'-nucleotidase, ecto (CD73) 0.0465089
ASPH aspartate beta-hydroxylase 0.0464351
ANKRD11 ankyrin repeat domain 11 0.0448243
SLC38A2 solute carrier family 38, member 2 0.0436483
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0433922
SH3KBP1 SH3-domain kinase binding protein 1 0.0428516
ANO6 anoctamin 6 0.0423874
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.041538
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.0412819
SAMD4A sterile alpha motif domain containing 4A 0.0404328
PRKCA protein kinase C, alpha 0.0401057
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0399258
IGFBP3 insulin-like growth factor binding protein 3 0.0385814
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0383029
SDC4 syndecan 4 0.0381093
SEPTIN9 septin 9 0.0380454
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0372452
BCAR3 breast cancer anti-estrogen resistance 3 0.0371888
FMNL2 formin-like 2 0.0364843
EEF2 eukaryotic translation elongation factor 2 0.0364327
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.036035
COL5A1 collagen, type V, alpha 1 0.0359857
RIGI RNA sensor RIG-I 0.035744
NAV2 neuron navigator 2 0.0357184
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0356363
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.03451
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.0344173
CD59 CD59 molecule, complement regulatory protein 0.0344135
NPAS2 neuronal PAS domain protein 2 0.0343993
NUMA1 nuclear mitotic apparatus protein 1 0.0341053
PTK2 protein tyrosine kinase 2 0.033774
AHNAK AHNAK nucleoprotein 0.0335926
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0327354
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0317543
EXOC4 exocyst complex component 4 0.0317504
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0316874
FMN1 formin 1 0.0314193
PCED1B PC-esterase domain containing 1B 0.0304924
FLNB filamin B, beta 0.0303906
EXT1 exostosin glycosyltransferase 1 0.029513
STXBP1 syntaxin binding protein 1 0.0289052
ZBTB20 zinc finger and BTB domain containing 20 0.0288502
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0288134
BICD1 bicaudal D homolog 1 (Drosophila) 0.0285883
WWTR1 WW domain containing transcription regulator 1 0.0283503
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0282664
MPRIP myosin phosphatase Rho interacting protein 0.0279208
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0272839
PBX3 pre-B-cell leukemia homeobox 3 0.0270403
ACTN1 actinin, alpha 1 0.026866
CYTH1 cytohesin 1 0.0268634
SHB Src homology 2 domain containing adaptor protein B 0.0266737
BHLHE40 basic helix-loop-helix family, member e40 0.0264845
STEAP3 STEAP family member 3, metalloreductase 0.026217
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0261252
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0261173
MSN moesin 0.0259001
ACTG1 actin gamma 1 0.0258883
CNOT12 CCR4-NOT transcription complex subunit 12 0.0258157
ZSWIM6 zinc finger, SWIM-type containing 6 0.0256994
RUNX1 runt-related transcription factor 1 0.0254092
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0252025
PRR16 proline rich 16 0.0251605
VCL vinculin 0.0249877
PFKP phosphofructokinase, platelet 0.024359
MYO9B myosin IXB 0.0240134
NFE2L1 nuclear factor, erythroid 2-like 1 0.0239836
USP22 ubiquitin specific peptidase 22 0.0239252
NCOR2 nuclear receptor corepressor 2 0.0237611
ITGAV integrin, alpha V 0.023529
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0235032
PGK1 phosphoglycerate kinase 1 0.023487
HSPA8 heat shock 70kDa protein 8 0.0228758
KIAA1671 KIAA1671 0.0227052
PLEK2 pleckstrin 2 0.022704

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.416897
PTMA prothymosin, alpha -0.0829071
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0794613
VIM vimentin -0.0785763
GOLGA4 golgin A4 -0.0756279
HILPDA hypoxia inducible lipid droplet-associated -0.0652019
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0531185
GNAS GNAS complex locus -0.0503776
MT2A metallothionein 2A -0.0479642
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0477039
ZNF292 zinc finger protein 292 -0.046417
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.0459152
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0454702
RBM39 RNA binding motif protein 39 -0.0453931
TMSB10 thymosin beta 10 -0.044752
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0389633
DIAPH3 diaphanous-related formin 3 -0.0372387
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0372228
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0367706
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0358727
DEK DEK proto-oncogene -0.0347691
RPL12 ribosomal protein L12 -0.0345614
RPS23 ribosomal protein S23 -0.0345207
EIF1 eukaryotic translation initiation factor 1 -0.0342029
PNISR PNN-interacting serine/arginine-rich protein -0.0340348
AKAP9 A kinase (PRKA) anchor protein 9 -0.0335436
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0335153
RPS8 ribosomal protein S8 -0.0329857
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0328391
RPL32 ribosomal protein L32 -0.0326983
SMC4 structural maintenance of chromosomes 4 -0.0326854
NAMPT nicotinamide phosphoribosyltransferase -0.0316199
LCORL ligand dependent nuclear receptor corepressor-like -0.0314944
MIS18BP1 MIS18 binding protein 1 -0.0303306
TPX2 TPX2, microtubule-associated -0.0302547
TXNRD1 thioredoxin reductase 1 -0.0292045
ANLN anillin, actin binding protein -0.0290905
SETD5 SET domain containing 5 -0.0290677
GGNBP2 gametogenetin binding protein 2 -0.0290672
WSB1 WD repeat and SOCS box containing 1 -0.0285181
CHD1 chromodomain helicase DNA binding protein 1 -0.028414
MATR3 matrin 3 -0.0281719
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0280269
RAB1A RAB1A, member RAS oncogene family -0.0279867
SEPTIN7 septin 7 -0.0279187
SEC24A SEC24 family member A -0.0274638
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0274221
NCOR1 nuclear receptor corepressor 1 -0.0272808
MTDH metadherin -0.0269453
WAC WW domain containing adaptor with coiled-coil -0.0268875
TMEM263 transmembrane protein 263 -0.0268377
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0264957
PPIG peptidylprolyl isomerase G (cyclophilin G) -0.0259534
ANKRD37 ankyrin repeat domain 37 -0.0254529
RPLP0 ribosomal protein, large, P0 -0.0251856
SGO2 shugoshin 2 -0.0248062
WDR45B WD repeat domain 45B -0.0247853
MORF4L2 mortality factor 4 like 2 -0.0247634
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.024739
FTL ferritin, light polypeptide -0.0245449
PHIP pleckstrin homology domain interacting protein -0.0244801
SRRM1 serine/arginine repetitive matrix 1 -0.0244138
RPS29 ribosomal protein S29 -0.0242262
RPLP1 ribosomal protein, large, P1 -0.0240236
RACK1 receptor for activated C kinase 1 -0.0239982
DSCAM Down syndrome cell adhesion molecule -0.0239672
CALU calumenin -0.0239169
ANKRD28 ankyrin repeat domain 28 -0.0237288
S100A9 S100 calcium binding protein A9 -0.0236784
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -0.0234824
NUP58 nucleoporin 58 -0.0233463
COG5 component of oligomeric golgi complex 5 -0.0231934
RBM25 RNA binding motif protein 25 -0.0231408
RAB6A RAB6A, member RAS oncogene family -0.0231395
TNPO1 transportin 1 -0.0230965
RB1CC1 RB1-inducible coiled-coil 1 -0.0230249
TTK TTK protein kinase -0.0228051
BBX bobby sox homolog (Drosophila) -0.02279
CNOT2 CCR4-NOT transcription complex, subunit 2 -0.0227736
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0226613
TRA2A transformer 2 alpha homolog (Drosophila) -0.0226081
RPS11 ribosomal protein S11 -0.0225196
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0224796
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0223188
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0222798
RPS12 ribosomal protein S12 -0.0220539
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0220329
SPAG9 sperm associated antigen 9 -0.0220054
RRBP1 ribosome binding protein 1 -0.0218422
NUP214 nucleoporin 214kDa -0.0217035
NAP1L1 nucleosome assembly protein 1-like 1 -0.0216664
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -0.0215459
ZNF207 zinc finger protein 207 -0.0214044
TM4SF1 transmembrane 4 L six family member 1 -0.021353
SNX14 sorting nexin 14 -0.0211098
KDM2A lysine (K)-specific demethylase 2A -0.0207543
APOLD1 apolipoprotein L domain containing 1 -0.0206074
HMGA1 high mobility group AT-hook 1 -0.0204846
PCNX1 pecanex 1 -0.0204307
IKBIP IKBKB interacting protein -0.0200515