| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.203227 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0887951 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0604395 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0553566 |
| COPA | coatomer protein complex, subunit alpha | 0.0504627 |
| MYADM | myeloid-associated differentiation marker | 0.0406335 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0370204 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.034646 |
| CD109 | CD109 molecule | 0.034022 |
| PCBP2 | poly(rC) binding protein 2 | 0.0324857 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0315707 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.028744 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0282976 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.028038 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0279495 |
| POTEF | POTE ankyrin domain family, member F | 0.0274332 |
| FNIP1 | folliculin interacting protein 1 | 0.0269295 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0259115 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0257133 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0251689 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0244951 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0238714 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0235931 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0222494 |
| HDAC9 | histone deacetylase 9 | 0.0219052 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0218529 |
| ADM | adrenomedullin | 0.0217762 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0217053 |
| OPTN | optineurin | 0.0213945 |
| ZNF148 | zinc finger protein 148 | 0.0207367 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0205986 |
| HIP1 | huntingtin interacting protein 1 | 0.0203127 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0202847 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0201263 |
| B2M | beta-2-microglobulin | 0.0198457 |
| MNT | MAX network transcriptional repressor | 0.0197697 |
| ERBIN | erbb2 interacting protein | 0.0197505 |
| FAM107B | family with sequence similarity 107, member B | 0.0197226 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0196812 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0196251 |
| MMP12 | matrix metallopeptidase 12 | 0.0194768 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0192692 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0189588 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0188615 |
| CYTH3 | cytohesin 3 | 0.018722 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0185236 |
| ITSN2 | intersectin 2 | 0.018449 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.018328 |
| HELZ | helicase with zinc finger | 0.0182034 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0181301 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0180765 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0180472 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0176521 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0172172 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0171412 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0169611 |
| GOLGA4 | golgin A4 | 0.0166191 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0163306 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.016305 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0162715 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0161607 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0161169 |
| UBAP1 | ubiquitin associated protein 1 | 0.0159469 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0157969 |
| CSTB | cystatin B (stefin B) | 0.0157268 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0157232 |
| INSIG2 | insulin induced gene 2 | 0.0157022 |
| S100A6 | S100 calcium binding protein A6 | 0.0156828 |
| NOTCH2 | notch 2 | 0.0156401 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0156032 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0155788 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.015537 |
| MSN | moesin | 0.0155332 |
| TGFB1 | transforming growth factor, beta 1 | 0.0154764 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0152925 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0152214 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0151822 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | 0.0149951 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.01498 |
| CTBP2 | C-terminal binding protein 2 | 0.0149082 |
| FBXO11 | F-box protein 11 | 0.0149009 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0147953 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0147502 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0145064 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0144838 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0142151 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0140028 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.013993 |
| RNF24 | ring finger protein 24 | 0.0137997 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0137493 |
| FOSL1 | FOS-like antigen 1 | 0.0137456 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0137356 |
| UBC | ubiquitin C | 0.0137049 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0136489 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0136031 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.01347 |
| NDRG1 | N-myc downstream regulated 1 | 0.0134354 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0132793 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.01324 |
| RAB18 | RAB18, member RAS oncogene family | 0.0132062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.211874 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.190727 |
| AHNAK | AHNAK nucleoprotein | -0.105757 |
| NAV1 | neuron navigator 1 | -0.101048 |
| CD44 | CD44 molecule (Indian blood group) | -0.0970074 |
| FBN1 | fibrillin 1 | -0.0845851 |
| THBS2 | thrombospondin 2 | -0.0813204 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0804386 |
| COL3A1 | collagen, type III, alpha 1 | -0.0715431 |
| COL1A2 | collagen, type I, alpha 2 | -0.063459 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0630074 |
| MX2 | MX dynamin-like GTPase 2 | -0.0589279 |
| MEIS2 | Meis homeobox 2 | -0.0589068 |
| MAP1B | microtubule-associated protein 1B | -0.0589062 |
| HLA-B | major histocompatibility complex, class I, B | -0.0545023 |
| MT2A | metallothionein 2A | -0.0503564 |
| RIGI | RNA sensor RIG-I | -0.0503306 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0489118 |
| TMSB4X | thymosin beta 4, X-linked | -0.0481603 |
| PODXL | podocalyxin-like | -0.0477735 |
| S100A10 | S100 calcium binding protein A10 | -0.047709 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0465201 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0460419 |
| RRBP1 | ribosome binding protein 1 | -0.0433604 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0412059 |
| LOXL2 | lysyl oxidase-like 2 | -0.0412037 |
| DST | dystonin | -0.0411105 |
| SUCNR1 | succinate receptor 1 | -0.0409571 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0397112 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0393783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0392927 |
| COL5A2 | collagen, type V, alpha 2 | -0.0392487 |
| TMSB10 | thymosin beta 10 | -0.0389732 |
| RNF213 | ring finger protein 213 | -0.0388753 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0384146 |
| PRELID2 | PRELI domain containing 2 | -0.038178 |
| COL5A1 | collagen, type V, alpha 1 | -0.0371292 |
| CAVIN1 | caveolae associated protein 1 | -0.0370517 |
| CDK6 | cyclin-dependent kinase 6 | -0.0369298 |
| GLIS3 | GLIS family zinc finger 3 | -0.0366518 |
| PRSS23 | protease, serine, 23 | -0.0356756 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.035066 |
| CCND1 | cyclin D1 | -0.0346315 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0340205 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0337389 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0334056 |
| LMNA | lamin A/C | -0.0333881 |
| OSMR | oncostatin M receptor | -0.032961 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0329239 |
| ANXA2 | annexin A2 | -0.0327157 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0325449 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0323638 |
| NAV2 | neuron navigator 2 | -0.0321653 |
| FLNA | filamin A, alpha | -0.0319358 |
| COL4A2 | collagen, type IV, alpha 2 | -0.031862 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0317881 |
| HLA-C | major histocompatibility complex, class I, C | -0.0314886 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0313799 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0310593 |
| HDLBP | high density lipoprotein binding protein | -0.0305628 |
| APP | amyloid beta (A4) precursor protein | -0.030424 |
| RUNX1 | runt-related transcription factor 1 | -0.0303932 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0301169 |
| ACTG1 | actin gamma 1 | -0.0294199 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0288592 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0285688 |
| PXDN | peroxidasin | -0.028352 |
| FSTL1 | follistatin-like 1 | -0.0277931 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0276943 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0274746 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0269261 |
| RRM2 | ribonucleotide reductase M2 | -0.0267371 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0261108 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0261105 |
| EFNA5 | ephrin-A5 | -0.0260995 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0259585 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0259047 |
| CENPF | centromere protein F, 350/400kDa | -0.0257036 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0256399 |
| RPL35A | ribosomal protein L35a | -0.0254931 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0250734 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0246658 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0244469 |
| NPR2 | natriuretic peptide receptor 2 | -0.024412 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0243421 |
| ARF1 | ADP-ribosylation factor 1 | -0.0242906 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0239935 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0238467 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0235821 |
| TDRD7 | tudor domain containing 7 | -0.0232156 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0231548 |
| ACTN4 | actinin, alpha 4 | -0.0230712 |
| ADAR | adenosine deaminase, RNA-specific | -0.0229796 |
| CDH13 | cadherin 13 | -0.0229438 |
| CANX | calnexin | -0.0227681 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0226842 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.022543 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0224742 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0224708 |
| RPS24 | ribosomal protein S24 | -0.0224092 |
