| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.159827 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0576239 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.049253 |
| ANXA1 | annexin A1 | 0.0433467 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0357456 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0348161 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0327088 |
| PGK1 | phosphoglycerate kinase 1 | 0.0288276 |
| RPLP0 | ribosomal protein, large, P0 | 0.0278903 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0274881 |
| KIF5B | kinesin family member 5B | 0.0256624 |
| TMEM41B | transmembrane protein 41B | 0.0246244 |
| CPOX | coproporphyrinogen oxidase | 0.0240781 |
| MATR3 | matrin 3 | 0.0233967 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0225336 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0224889 |
| KLHL24 | kelch-like family member 24 | 0.0221971 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.0221595 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0202189 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0199257 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0188408 |
| LMO7 | LIM domain 7 | 0.0185905 |
| GCG | glucagon | 0.0185058 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0180172 |
| VMP1 | vacuole membrane protein 1 | 0.0178964 |
| COPA | coatomer protein complex, subunit alpha | 0.0177201 |
| YEATS2 | YEATS domain containing 2 | 0.0176318 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0174178 |
| ARRDC3 | arrestin domain containing 3 | 0.017092 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0169356 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0168961 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0160201 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0158667 |
| TMEM14B | transmembrane protein 14B | 0.0156384 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0154984 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0153707 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0152894 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0152796 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0150868 |
| CEP350 | centrosomal protein 350kDa | 0.015031 |
| FBL | fibrillarin | 0.0145701 |
| UBXN2A | UBX domain protein 2A | 0.0145202 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0145097 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0144883 |
| TSNAX | translin-associated factor X | 0.01445 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0143795 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0141231 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0140884 |
| CEP70 | centrosomal protein 70kDa | 0.0139435 |
| RNF145 | ring finger protein 145 | 0.0139132 |
| KIF18B | kinesin family member 18B | 0.0135948 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0135208 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0135146 |
| FTL | ferritin, light polypeptide | 0.0134935 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0134706 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0133237 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0132067 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0130228 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.012946 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0128794 |
| CLDN1 | claudin 1 | 0.0127541 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0127251 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0127236 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0127129 |
| RPL12 | ribosomal protein L12 | 0.0126941 |
| RLF | rearranged L-myc fusion | 0.0126803 |
| WDR45B | WD repeat domain 45B | 0.0126503 |
| TCERG1 | transcription elongation regulator 1 | 0.0124155 |
| ETNK1 | ethanolamine kinase 1 | 0.0124126 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0123035 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0122837 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0122529 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0122397 |
| EPHA6 | EPH receptor A6 | 0.0122336 |
| INSIG2 | insulin induced gene 2 | 0.0120913 |
| RSF1 | remodeling and spacing factor 1 | 0.0120259 |
| GOLT1B | golgi transport 1B | 0.0120195 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0119754 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0118735 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.011715 |
| THOC2 | THO complex 2 | 0.0117145 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0116442 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0116328 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0116233 |
| UBE3A | ubiquitin protein ligase E3A | 0.0116172 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0115643 |
| DSPP | dentin sialophosphoprotein | 0.0115561 |
| TULP3 | tubby like protein 3 | 0.0115374 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0115126 |
| INTS10 | integrator complex subunit 10 | 0.0115007 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0110878 |
| ANKRD26 | ankyrin repeat domain 26 | 0.0110396 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0109585 |
| MRPS5 | mitochondrial ribosomal protein S5 | 0.0109583 |
| RBM25 | RNA binding motif protein 25 | 0.0109092 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | 0.0108889 |
| LDHA | lactate dehydrogenase A | 0.0108505 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0107737 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0107562 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0107259 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.252319 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.130751 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.112052 |
| PCDH7 | protocadherin 7 | -0.0974902 |
| HMGA2 | high mobility group AT-hook 2 | -0.0902036 |
| TMSB10 | thymosin beta 10 | -0.0847809 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.069301 |
| YAP1 | Yes-associated protein 1 | -0.0664216 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0663632 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0637491 |
| DST | dystonin | -0.0578754 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0577139 |
| CMIP | c-Maf inducing protein | -0.0546481 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0509272 |
| MMP12 | matrix metallopeptidase 12 | -0.0497771 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0482789 |
| AHNAK | AHNAK nucleoprotein | -0.0479981 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0477441 |
| VIM | vimentin | -0.0473783 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0468994 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0467337 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0451817 |
| ACTG1 | actin gamma 1 | -0.0442856 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.041142 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0400538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0392917 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0391541 |
| EHBP1 | EH domain binding protein 1 | -0.0383806 |
| RPS27A | ribosomal protein S27a | -0.0380814 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0371329 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0370751 |
| UBC | ubiquitin C | -0.0360771 |
| RPL23 | ribosomal protein L23 | -0.0353482 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0353457 |
| ASPH | aspartate beta-hydroxylase | -0.0352227 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0342358 |
| PDGFC | platelet derived growth factor C | -0.0341069 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0340605 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0338888 |
| MYPN | myopalladin | -0.0327521 |
| CDK6 | cyclin-dependent kinase 6 | -0.0324454 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0319328 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0314419 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.031061 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0309139 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0308967 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0306823 |
| ZNF804A | zinc finger protein 804A | -0.03 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0299885 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299546 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0296546 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0292809 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0277617 |
| COMMD10 | COMM domain containing 10 | -0.0275176 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0273728 |
| INTS6 | integrator complex subunit 6 | -0.0272487 |
| NHSL1 | NHS-like 1 | -0.0271315 |
| PCBP2 | poly(rC) binding protein 2 | -0.026804 |
| CEP112 | centrosomal protein 112kDa | -0.026366 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0261817 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0259666 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.025918 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0256679 |
| JMJD1C | jumonji domain containing 1C | -0.0256418 |
| ADIPOR2 | adiponectin receptor 2 | -0.0256365 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0253586 |
| FUS | FUS RNA binding protein | -0.0253272 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0247109 |
| HDAC9 | histone deacetylase 9 | -0.0245732 |
| CALR | calreticulin | -0.0243962 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0243639 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0241543 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0241327 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0239051 |
| DIAPH1 | diaphanous-related formin 1 | -0.0236885 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0236733 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0234287 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0230637 |
| RBM39 | RNA binding motif protein 39 | -0.0229662 |
| TPM3 | tropomyosin 3 | -0.0229055 |
| EDARADD | EDAR-associated death domain | -0.0228591 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0226776 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0225882 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0224781 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0222666 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0222475 |
| NABP1 | nucleic acid binding protein 1 | -0.0219571 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0219371 |
| CANX | calnexin | -0.0219217 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0218111 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0217074 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0215985 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.021564 |
| RASAL2 | RAS protein activator like 2 | -0.0214821 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0214115 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0214092 |
| AFF4 | AF4/FMR2 family, member 4 | -0.021195 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0211723 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.021158 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0211006 |
