| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0842219 |
| VIM | vimentin | 0.0812644 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.080078 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0657657 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0614359 |
| NDRG1 | N-myc downstream regulated 1 | 0.0538577 |
| ASPH | aspartate beta-hydroxylase | 0.0513463 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.04988 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0491392 |
| MEF2A | myocyte enhancer factor 2A | 0.0478112 |
| PCBP2 | poly(rC) binding protein 2 | 0.0453017 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0414635 |
| DTNA | dystrobrevin, alpha | 0.0413673 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0402904 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0402525 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039879 |
| FAM13A | family with sequence similarity 13, member A | 0.0366151 |
| PLAT | plasminogen activator, tissue | 0.0333751 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.03293 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.03232 |
| VEGFA | vascular endothelial growth factor A | 0.0313973 |
| PTMA | prothymosin, alpha | 0.0302921 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0295019 |
| FN1 | fibronectin 1 | 0.0290051 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0281336 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0275126 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0273242 |
| CXXC5 | CXXC finger protein 5 | 0.0271665 |
| CENPF | centromere protein F, 350/400kDa | 0.0267965 |
| QKI | QKI, KH domain containing, RNA binding | 0.0265459 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0264858 |
| STC1 | stanniocalcin 1 | 0.0263104 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0262812 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0262797 |
| RPS3 | ribosomal protein S3 | 0.0262725 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262106 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0261839 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0261335 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0261012 |
| HELZ | helicase with zinc finger | 0.0259448 |
| CDH13 | cadherin 13 | 0.0258304 |
| SEPTIN9 | septin 9 | 0.0253918 |
| RPL35A | ribosomal protein L35a | 0.0244521 |
| ANXA1 | annexin A1 | 0.0241618 |
| MSI2 | musashi RNA-binding protein 2 | 0.022746 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0223767 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0222048 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0219591 |
| WDR45B | WD repeat domain 45B | 0.0219213 |
| LOXL2 | lysyl oxidase-like 2 | 0.0215556 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0213297 |
| POTEF | POTE ankyrin domain family, member F | 0.0212833 |
| ARF4 | ADP-ribosylation factor 4 | 0.0212034 |
| TPM3 | tropomyosin 3 | 0.0210638 |
| PRR11 | proline rich 11 | 0.0208205 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0207201 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0207044 |
| HMGB2 | high mobility group box 2 | 0.0206518 |
| CENPE | centromere protein E, 312kDa | 0.0206092 |
| KIAA1217 | KIAA1217 | 0.0204182 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0202636 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.0201124 |
| ADM | adrenomedullin | 0.0200642 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0200563 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0199963 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0197383 |
| HIP1 | huntingtin interacting protein 1 | 0.019601 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0195287 |
| HDGF | hepatoma-derived growth factor | 0.0189575 |
| PLIN2 | perilipin 2 | 0.0189021 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0188959 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.018777 |
| PTK2 | protein tyrosine kinase 2 | 0.0186523 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0185643 |
| PKM | pyruvate kinase, muscle | 0.0184469 |
| MEMO1 | mediator of cell motility 1 | 0.0184351 |
| ZNF148 | zinc finger protein 148 | 0.018425 |
| IKBIP | IKBKB interacting protein | 0.0183235 |
| TAGLN2 | transgelin 2 | 0.018165 |
| HDAC9 | histone deacetylase 9 | 0.0180885 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0180636 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0179008 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.017782 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0175972 |
| DIAPH3 | diaphanous-related formin 3 | 0.017566 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0175338 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0172809 |
| SMAP1 | small ArfGAP 1 | 0.0171959 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0171572 |
| XPO1 | exportin 1 | 0.0170324 |
| TPX2 | TPX2, microtubule-associated | 0.0170069 |
| RTN4 | reticulon 4 | 0.0168983 |
| SET | SET nuclear proto-oncogene | 0.0168202 |
| MTF2 | metal response element binding transcription factor 2 | 0.0168045 |
| ATRN | attractin | 0.0167628 |
| CCDC88A | coiled-coil domain containing 88A | 0.0166107 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0165134 |
| NUF2 | NUF2, NDC80 kinetochore complex component | 0.0164414 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0164378 |
| HMGA1 | high mobility group AT-hook 1 | 0.0164376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SYT1 | synaptotagmin I | -0.167461 |
| IGF2 | insulin-like growth factor 2 | -0.152967 |
| FMN1 | formin 1 | -0.120419 |
| LSAMP | limbic system-associated membrane protein | -0.118902 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.108409 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.103291 |
| MEIS2 | Meis homeobox 2 | -0.10102 |
| VCL | vinculin | -0.0915514 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0786955 |
| NRG1 | neuregulin 1 | -0.0779963 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0721119 |
| TLE4 | transducin-like enhancer of split 4 | -0.0669692 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0651191 |
| KLHL13 | kelch-like family member 13 | -0.0646382 |
| DST | dystonin | -0.0636248 |
| COL3A1 | collagen, type III, alpha 1 | -0.0608189 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0581843 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0569472 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0561639 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0523076 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0520008 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.050666 |
| AOPEP | aminopeptidase O (putative) | -0.0495582 |
| FRMD4A | FERM domain containing 4A | -0.0486346 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0483421 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0471422 |
| GLCCI1 | glucocorticoid induced 1 | -0.0461327 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0443945 |
| RIGI | RNA sensor RIG-I | -0.0431728 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0428996 |
| HMBOX1 | homeobox containing 1 | -0.0428241 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0427732 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0424473 |
| RNF213 | ring finger protein 213 | -0.0420999 |
| PDE10A | phosphodiesterase 10A | -0.0411735 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0406441 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.038964 |
| BPTF | bromodomain PHD finger transcription factor | -0.038792 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.038628 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0379043 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0372974 |
| GAB2 | GRB2-associated binding protein 2 | -0.037249 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0368388 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.036236 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0356193 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0353295 |
| MAP1B | microtubule-associated protein 1B | -0.0351669 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0350624 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0345634 |
| THBS1 | thrombospondin 1 | -0.0345393 |
| ZNF804A | zinc finger protein 804A | -0.0343968 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0333593 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0333201 |
| NRP1 | neuropilin 1 | -0.0329533 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0328107 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.032749 |
| ANGPT1 | angiopoietin 1 | -0.0326733 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0323585 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0322427 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.032215 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0319427 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0313519 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0313356 |
| PLPP1 | phospholipid phosphatase 1 | -0.0312615 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0310344 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0308557 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0305481 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0305406 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0305345 |
| RALYL | RALY RNA binding protein-like | -0.0304677 |
| SH3PXD2B | SH3 and PX domains 2B | -0.030412 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0302629 |
| NBEA | neurobeachin | -0.0301305 |
| RPL23 | ribosomal protein L23 | -0.0300569 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0299716 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0295877 |
| FAM107B | family with sequence similarity 107, member B | -0.0293963 |
| SIK2 | salt-inducible kinase 2 | -0.0293459 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0288798 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.028688 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.028322 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0283187 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0282037 |
| DNM3 | dynamin 3 | -0.0279168 |
| MAP4 | microtubule-associated protein 4 | -0.0278135 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0275272 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0274206 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0272133 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.027125 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0267703 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0266177 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0265755 |
| IRS1 | insulin receptor substrate 1 | -0.0264459 |
| AHNAK | AHNAK nucleoprotein | -0.0263694 |
| STK38L | serine/threonine kinase 38 like | -0.026355 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | -0.0260506 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0254571 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0253402 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0253179 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0252962 |
