| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaprozin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0913875 |
| TXNIP | thioredoxin interacting protein | 0.0729443 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0701498 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0551268 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0516352 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0482738 |
| UBC | ubiquitin C | 0.0445293 |
| B2M | beta-2-microglobulin | 0.0432761 |
| PGK1 | phosphoglycerate kinase 1 | 0.0413319 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0409928 |
| LIMA1 | LIM domain and actin binding 1 | 0.0387043 |
| RNF149 | ring finger protein 149 | 0.0386198 |
| CLTC | clathrin, heavy chain (Hc) | 0.0375634 |
| KIF16B | kinesin family member 16B | 0.0373895 |
| CANX | calnexin | 0.0371549 |
| LYZ | lysozyme | 0.036829 |
| WDR45B | WD repeat domain 45B | 0.0366951 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0358291 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0351591 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0350567 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0340465 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0338207 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0331729 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0327467 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.032118 |
| MEF2A | myocyte enhancer factor 2A | 0.0305808 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0304712 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0304366 |
| ERBIN | erbb2 interacting protein | 0.0300927 |
| NDRG1 | N-myc downstream regulated 1 | 0.0294954 |
| PCBP2 | poly(rC) binding protein 2 | 0.0287636 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.0286747 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0284597 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0282946 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0279524 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0272938 |
| NIPSNAP2 | nipsnap homolog 2 | 0.02722 |
| YY1 | YY1 transcription factor | 0.0269613 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0264848 |
| SMIM14 | small integral membrane protein 14 | 0.026364 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0263151 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0262699 |
| CEP350 | centrosomal protein 350kDa | 0.0258558 |
| RPS6 | ribosomal protein S6 | 0.0254465 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0250727 |
| CDHR2 | cadherin-related family member 2 | 0.0250199 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.025017 |
| HLA-B | major histocompatibility complex, class I, B | 0.0247408 |
| COPA | coatomer protein complex, subunit alpha | 0.0242243 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0240339 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0240278 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0236684 |
| IFNGR1 | interferon gamma receptor 1 | 0.0234959 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0231929 |
| LDHA | lactate dehydrogenase A | 0.0227223 |
| TMEM51 | transmembrane protein 51 | 0.0226744 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0223015 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0219413 |
| EPCAM | epithelial cell adhesion molecule | 0.0219096 |
| PTGR1 | prostaglandin reductase 1 | 0.0218365 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.02162 |
| SCFD1 | sec1 family domain containing 1 | 0.0215574 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0214706 |
| THOC2 | THO complex 2 | 0.0214611 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0214428 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0213486 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0213076 |
| GRAMD2B | GRAM domain containing 2B | 0.020611 |
| ZNF652 | zinc finger protein 652 | 0.0203972 |
| ANXA11 | annexin A11 | 0.0201563 |
| APOL1 | apolipoprotein L, 1 | 0.0200466 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0199507 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0198999 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.019872 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0196958 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0196384 |
| RPS12 | ribosomal protein S12 | 0.0193556 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0193133 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0193088 |
| RPLP0 | ribosomal protein, large, P0 | 0.0191867 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0190093 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0189332 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0189171 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0188328 |
| TAOK3 | TAO kinase 3 | 0.0187866 |
| CDCP1 | CUB domain containing protein 1 | 0.0186155 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0185401 |
| ZNF148 | zinc finger protein 148 | 0.0185385 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0183167 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0182745 |
| DIAPH1 | diaphanous-related formin 1 | 0.0182577 |
| DSTN | destrin (actin depolymerizing factor) | 0.0182238 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0182171 |
| HLA-E | major histocompatibility complex, class I, E | 0.0181634 |
| SYTL3 | synaptotagmin-like 3 | 0.0181023 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0180824 |
| ZNF609 | zinc finger protein 609 | 0.0180666 |
| DNM2 | dynamin 2 | 0.0178844 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0177703 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.017727 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.178166 |
| INTS6 | integrator complex subunit 6 | -0.159956 |
| LMO7 | LIM domain 7 | -0.103048 |
| SQSTM1 | sequestosome 1 | -0.0988263 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0949876 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0940131 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0930243 |
| RNF213 | ring finger protein 213 | -0.0899593 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.085959 |
| SP100 | SP100 nuclear antigen | -0.0850969 |
| VCL | vinculin | -0.0813476 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0810448 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0792693 |
| RIGI | RNA sensor RIG-I | -0.0726236 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0694357 |
| ANXA2 | annexin A2 | -0.0689567 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0656611 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.064498 |
| LCN2 | lipocalin 2 | -0.0571768 |
| EPHB2 | EPH receptor B2 | -0.0564212 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0562935 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0535813 |
| RUNX1 | runt-related transcription factor 1 | -0.0535729 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0517669 |
| PLSCR2 | phospholipid scramblase 2 | -0.0517214 |
| EFNB2 | ephrin-B2 | -0.0508123 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0506734 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0498177 |
| MYO1E | myosin IE | -0.0476732 |
| PLSCR1 | phospholipid scramblase 1 | -0.0448083 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.043986 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0432972 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0410327 |
| ATP11A | ATPase, class VI, type 11A | -0.0409141 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.040648 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0405835 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0400671 |
| XAF1 | XIAP associated factor 1 | -0.0396723 |
| MSI2 | musashi RNA-binding protein 2 | -0.0393493 |
| SERINC5 | serine incorporator 5 | -0.0370726 |
| MECOM | MDS1 and EVI1 complex locus | -0.037057 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0368713 |
| RNF43 | ring finger protein 43 | -0.0368134 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.036375 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0360382 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0359171 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0342081 |
| MX2 | MX dynamin-like GTPase 2 | -0.0341413 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0341025 |
| IRF1 | interferon regulatory factor 1 | -0.0327918 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0325204 |
| NCKAP5 | NCK-associated protein 5 | -0.0324595 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0322191 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0322036 |
| MAP7 | microtubule-associated protein 7 | -0.0322027 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0315162 |
| SMAD3 | SMAD family member 3 | -0.0310311 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0306948 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0306929 |
| NCALD | neurocalcin delta | -0.0304277 |
| SYT1 | synaptotagmin I | -0.0303525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0301677 |
| HDAC4 | histone deacetylase 4 | -0.0298669 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0296606 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0295437 |
| NABP1 | nucleic acid binding protein 1 | -0.0294255 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0292399 |
| USP15 | ubiquitin specific peptidase 15 | -0.0291549 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0289787 |
| PRKCA | protein kinase C, alpha | -0.0289153 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0285732 |
| WWOX | WW domain containing oxidoreductase | -0.0285516 |
| EGR1 | early growth response 1 | -0.0283371 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0280988 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0278139 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0276476 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0275414 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0275353 |
| FBXO39 | F-box protein 39 | -0.0272802 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0268856 |
| SPATA13 | spermatogenesis associated 13 | -0.0264843 |
| MX1 | MX dynamin-like GTPase 1 | -0.0264238 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0262739 |
| EZR | ezrin | -0.0260571 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0259977 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0258026 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0257699 |
| RPL23 | ribosomal protein L23 | -0.0255799 |
| POF1B | premature ovarian failure, 1B | -0.0253983 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0252214 |
| LAMB3 | laminin, beta 3 | -0.0250347 |
| NPSR1 | neuropeptide S receptor 1 | -0.0246629 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.0246542 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0243547 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.023908 |
| IRS2 | insulin receptor substrate 2 | -0.023628 |
| CENPP | centromere protein P | -0.0236246 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0235475 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0233887 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0227198 |