| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP13A3 | ATPase type 13A3 | 0.120072 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0832454 |
| GOLGA4 | golgin A4 | 0.0596016 |
| STC1 | stanniocalcin 1 | 0.0468543 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411309 |
| CADM1 | cell adhesion molecule 1 | 0.0409816 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0375078 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.036632 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0358301 |
| ARRDC3 | arrestin domain containing 3 | 0.0354774 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0336483 |
| TFG | TRK-fused gene | 0.0311215 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.030049 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0299993 |
| USP3 | ubiquitin specific peptidase 3 | 0.0299032 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0289084 |
| ZNF292 | zinc finger protein 292 | 0.0284965 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0282513 |
| RASA2 | RAS p21 protein activator 2 | 0.0281992 |
| OGA | O-GlcNAcase | 0.0279247 |
| B2M | beta-2-microglobulin | 0.0278881 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0276371 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.027365 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0272139 |
| SPAG9 | sperm associated antigen 9 | 0.0268537 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0266511 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263872 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0262034 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0258614 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0256783 |
| PDE8A | phosphodiesterase 8A | 0.0256718 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.025608 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0255306 |
| FMNL2 | formin-like 2 | 0.025482 |
| RLF | rearranged L-myc fusion | 0.0251848 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0251325 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0237958 |
| TMEM165 | transmembrane protein 165 | 0.0232723 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.023021 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0228012 |
| MT2A | metallothionein 2A | 0.022676 |
| SQLE | squalene epoxidase | 0.0226154 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0221663 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0219561 |
| POSTN | periostin, osteoblast specific factor | 0.0218481 |
| HIP1 | huntingtin interacting protein 1 | 0.0217288 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0214442 |
| COG5 | component of oligomeric golgi complex 5 | 0.0214171 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0212953 |
| TRAM1 | translocation associated membrane protein 1 | 0.021236 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.021016 |
| MRTFA | myocardin related transcription factor A | 0.0208718 |
| PCBP2 | poly(rC) binding protein 2 | 0.0204314 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0202908 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0198144 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.019647 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0196161 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0193497 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0193388 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0190182 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0188529 |
| ZNF148 | zinc finger protein 148 | 0.0187753 |
| RIOK3 | RIO kinase 3 | 0.0187609 |
| MALT1 | MALT1 paracaspase | 0.0183093 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0181855 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0179344 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0179295 |
| FOSL1 | FOS-like antigen 1 | 0.017876 |
| XPO1 | exportin 1 | 0.0177133 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0176868 |
| SP3 | Sp3 transcription factor | 0.0175476 |
| FOXJ3 | forkhead box J3 | 0.0175355 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0175014 |
| NKTR | natural killer cell triggering receptor | 0.017435 |
| KIF1B | kinesin family member 1B | 0.0171521 |
| SUCO | SUN domain containing ossification factor | 0.0169981 |
| FBXO42 | F-box protein 42 | 0.0169694 |
| ATP11B | ATPase, class VI, type 11B | 0.0169313 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0169113 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0167229 |
| ICAM1 | intercellular adhesion molecule 1 | 0.016694 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0166787 |
| SRP54 | signal recognition particle 54kDa | 0.0165829 |
| TMEM41B | transmembrane protein 41B | 0.016461 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0163195 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0162942 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0162938 |
| HELZ | helicase with zinc finger | 0.0161939 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0161851 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0161602 |
| ADM | adrenomedullin | 0.0161399 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.016131 |
| WDR45B | WD repeat domain 45B | 0.0160077 |
| RBM39 | RNA binding motif protein 39 | 0.0159985 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0159019 |
| CLINT1 | clathrin interactor 1 | 0.0158088 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0157778 |
| MLF1 | myeloid leukemia factor 1 | 0.0157657 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0157483 |
| RNF24 | ring finger protein 24 | 0.0157458 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.269605 |
| FN1 | fibronectin 1 | -0.153617 |
| COL6A3 | collagen, type VI, alpha 3 | -0.14844 |
| CDH13 | cadherin 13 | -0.120779 |
| FBN1 | fibrillin 1 | -0.105209 |
| EXT1 | exostosin glycosyltransferase 1 | -0.102467 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0972429 |
| COL1A1 | collagen, type I, alpha 1 | -0.0849711 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0797844 |
| GLIS3 | GLIS family zinc finger 3 | -0.077659 |
| CALD1 | caldesmon 1 | -0.0682069 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0678468 |
| ASPH | aspartate beta-hydroxylase | -0.0639785 |
| COL5A1 | collagen, type V, alpha 1 | -0.0623033 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.061735 |
| VIM | vimentin | -0.0584737 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0568566 |
| VCL | vinculin | -0.0534468 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0533769 |
| TMSB10 | thymosin beta 10 | -0.0530572 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0503482 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0481134 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0477106 |
| HMGA2 | high mobility group AT-hook 2 | -0.0473868 |
| DST | dystonin | -0.0470855 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0467838 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0464203 |
| VCAN | versican | -0.043384 |
| CNTN5 | contactin 5 | -0.0419851 |
| AHNAK | AHNAK nucleoprotein | -0.0416866 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0414962 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0410356 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0407459 |
| CD44 | CD44 molecule (Indian blood group) | -0.0402905 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0396196 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0384052 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0345572 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0342839 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0339938 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0329475 |
| PALLD | palladin, cytoskeletal associated protein | -0.0325855 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0322766 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.031789 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0316982 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0313513 |
| MAP1B | microtubule-associated protein 1B | -0.0312392 |
| EGFR | epidermal growth factor receptor | -0.0294857 |
| ACTG1 | actin gamma 1 | -0.0291913 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0289157 |
| LOX | lysyl oxidase | -0.027812 |
| NREP | neuronal regeneration related protein | -0.0277528 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276696 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0274549 |
| COL1A2 | collagen, type I, alpha 2 | -0.0271031 |
| SDC2 | syndecan 2 | -0.0266056 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0264064 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.026188 |
| INHBA | inhibin, beta A | -0.0259317 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0258558 |
| NABP1 | nucleic acid binding protein 1 | -0.0250903 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0249413 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.02494 |
| FOXP1 | forkhead box P1 | -0.0249223 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0246951 |
| ATXN1 | ataxin 1 | -0.0246887 |
| DGKI | diacylglycerol kinase, iota | -0.0245721 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0245488 |
| EPHB1 | EPH receptor B1 | -0.0241172 |
| HDAC9 | histone deacetylase 9 | -0.0241114 |
| FTL | ferritin, light polypeptide | -0.0240854 |
| NEK10 | NIMA-related kinase 10 | -0.0235891 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0235301 |
| GOLGB1 | golgin B1 | -0.0233043 |
| NAV1 | neuron navigator 1 | -0.02326 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231225 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.022657 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.022503 |
| VEGFA | vascular endothelial growth factor A | -0.02196 |
| RRBP1 | ribosome binding protein 1 | -0.021957 |
| CUX1 | cut-like homeobox 1 | -0.0219426 |
| INTS6 | integrator complex subunit 6 | -0.0216308 |
| TPM1 | tropomyosin 1 (alpha) | -0.0214703 |
| EBF1 | early B-cell factor 1 | -0.0213548 |
| EGR1 | early growth response 1 | -0.0210873 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0208413 |
| RIGI | RNA sensor RIG-I | -0.020797 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0206844 |
| PRSS23 | protease, serine, 23 | -0.0206278 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0205028 |
| SQSTM1 | sequestosome 1 | -0.0204848 |
| FRMD4A | FERM domain containing 4A | -0.0201799 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0201375 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0200242 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0200187 |
| RUNX1 | runt-related transcription factor 1 | -0.0199069 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0198338 |
| HMCN1 | hemicentin 1 | -0.0196402 |
| EXOC4 | exocyst complex component 4 | -0.0194602 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0188931 |
| CDK6 | cyclin-dependent kinase 6 | -0.0188132 |
