| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.104321 |
| PTMA | prothymosin, alpha | 0.0963758 |
| MEF2A | myocyte enhancer factor 2A | 0.0905037 |
| GOLGA4 | golgin A4 | 0.0865849 |
| ANXA1 | annexin A1 | 0.0862617 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0833075 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0774777 |
| SPAG9 | sperm associated antigen 9 | 0.0759261 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0694914 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.069154 |
| EZR | ezrin | 0.0663407 |
| PGK1 | phosphoglycerate kinase 1 | 0.0660081 |
| SQLE | squalene epoxidase | 0.0648515 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0635342 |
| OGA | O-GlcNAcase | 0.0586254 |
| EMP1 | epithelial membrane protein 1 | 0.0567724 |
| SUCO | SUN domain containing ossification factor | 0.0534726 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0525387 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0496461 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0478675 |
| DSTN | destrin (actin depolymerizing factor) | 0.0472674 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0469876 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0465392 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0461915 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.045511 |
| RBM39 | RNA binding motif protein 39 | 0.0453153 |
| ENO1 | enolase 1, (alpha) | 0.0442246 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0435681 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0435251 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0432322 |
| NDRG1 | N-myc downstream regulated 1 | 0.0421858 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0418233 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0413787 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0403433 |
| XPO1 | exportin 1 | 0.0399624 |
| FLNB | filamin B, beta | 0.0387028 |
| COPA | coatomer protein complex, subunit alpha | 0.038493 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0379694 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0379046 |
| RNF145 | ring finger protein 145 | 0.0378727 |
| B2M | beta-2-microglobulin | 0.0376276 |
| PKM | pyruvate kinase, muscle | 0.0365386 |
| LDHA | lactate dehydrogenase A | 0.0364874 |
| KRT17 | keratin 17, type I | 0.0361997 |
| MYO10 | myosin X | 0.0357942 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357021 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0351128 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0343957 |
| RLF | rearranged L-myc fusion | 0.0343127 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0341566 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.03394 |
| SLMAP | sarcolemma associated protein | 0.033616 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0336097 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0333212 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0332331 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0331976 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.033168 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0328839 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0328781 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0327353 |
| TMSB10 | thymosin beta 10 | 0.0326919 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0324198 |
| CANX | calnexin | 0.0322293 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0317494 |
| ANLN | anillin, actin binding protein | 0.0317118 |
| MTSS1 | metastasis suppressor 1 | 0.0315276 |
| LMNA | lamin A/C | 0.0314629 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.031343 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0310315 |
| HELZ | helicase with zinc finger | 0.0309565 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0307737 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0307656 |
| USP3 | ubiquitin specific peptidase 3 | 0.0305662 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0302138 |
| RIOK3 | RIO kinase 3 | 0.0299205 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0297538 |
| ADM | adrenomedullin | 0.0296322 |
| NUP58 | nucleoporin 58 | 0.029629 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0296021 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0294015 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0292422 |
| TMEM165 | transmembrane protein 165 | 0.02908 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.028825 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0286295 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0286238 |
| SLK | STE20-like kinase | 0.0283799 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0279678 |
| CALR | calreticulin | 0.027692 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0276895 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0273673 |
| GNAS | GNAS complex locus | 0.027263 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0272613 |
| FOXO3 | forkhead box O3 | 0.027208 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0269588 |
| SRP54 | signal recognition particle 54kDa | 0.02694 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0269297 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0267304 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0267009 |
| ARRDC3 | arrestin domain containing 3 | 0.0266932 |
| KIAA1217 | KIAA1217 | 0.0265993 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.149503 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.107699 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0999068 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.088179 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0880532 |
| OSMR | oncostatin M receptor | -0.0649428 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0537871 |
| EFNA5 | ephrin-A5 | -0.0530696 |
| FOXO1 | forkhead box O1 | -0.0496782 |
| MECOM | MDS1 and EVI1 complex locus | -0.0492453 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0464159 |
| FOXP1 | forkhead box P1 | -0.0458541 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0434275 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0402408 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0398199 |
| RAD51B | RAD51 paralog B | -0.0393941 |
| EXOC4 | exocyst complex component 4 | -0.0373247 |
| BCL2L1 | BCL2-like 1 | -0.0369075 |
| SMYD3 | SET and MYND domain containing 3 | -0.0366296 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0346613 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.034594 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0323235 |
| PLAT | plasminogen activator, tissue | -0.0318345 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0314909 |
| PRELID2 | PRELI domain containing 2 | -0.0311503 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0295129 |
| HMGA2 | high mobility group AT-hook 2 | -0.0293697 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0287952 |
| RIN2 | Ras and Rab interactor 2 | -0.0276313 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0274985 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.026787 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0260029 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0260023 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0259344 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0252864 |
| NRG1 | neuregulin 1 | -0.0247412 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0246731 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0244856 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0242091 |
| CORO2A | coronin, actin binding protein, 2A | -0.0238886 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0235952 |
| RASAL2 | RAS protein activator like 2 | -0.0230812 |
| AOPEP | aminopeptidase O (putative) | -0.0230488 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0229493 |
| DUSP4 | dual specificity phosphatase 4 | -0.0228161 |
| HLA-B | major histocompatibility complex, class I, B | -0.0225894 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0225596 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0225299 |
| UTRN | utrophin | -0.0218361 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0217401 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0216376 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0215587 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0215293 |
| SOX13 | SRY (sex determining region Y)-box 13 | -0.0215216 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0215011 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0214377 |
| SEPTIN9 | septin 9 | -0.0213238 |
| PALLD | palladin, cytoskeletal associated protein | -0.0212696 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0211585 |
| CDK6 | cyclin-dependent kinase 6 | -0.0210987 |
| ADIRF | adipogenesis regulatory factor | -0.0207423 |
| INTS6 | integrator complex subunit 6 | -0.0202121 |
| EXOC6B | exocyst complex component 6B | -0.0201038 |
| CMIP | c-Maf inducing protein | -0.0198812 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0196465 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0196232 |
| LUZP1 | leucine zipper protein 1 | -0.0189881 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0189719 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0189176 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0189076 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0188898 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0188174 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0187553 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0187519 |
| RPL9 | ribosomal protein L9 | -0.0187295 |
| WDR70 | WD repeat domain 70 | -0.0186615 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0185781 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0185193 |
| NEK7 | NIMA-related kinase 7 | -0.0182236 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0180536 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0180481 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0179278 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0179008 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0178591 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0177999 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0177589 |
| DGKH | diacylglycerol kinase, eta | -0.0177509 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0176635 |
| SYNJ2 | synaptojanin 2 | -0.0175386 |
| SOX7 | SRY (sex determining region Y)-box 7 | -0.0174547 |
| LMO7 | LIM domain 7 | -0.0173874 |
| AHNAK | AHNAK nucleoprotein | -0.0173341 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0173195 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0173078 |
| KLF12 | Kruppel-like factor 12 | -0.0172704 |
| PLXNA2 | plexin A2 | -0.0172324 |
| STK10 | serine/threonine kinase 10 | -0.0172236 |
| NBEA | neurobeachin | -0.0171879 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0171042 |
| MEIS2 | Meis homeobox 2 | -0.0170786 |
