| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.125865 |
| ANXA2 | annexin A2 | 0.11543 |
| PGK1 | phosphoglycerate kinase 1 | 0.0843885 |
| EREG | epiregulin | 0.0699013 |
| TXNIP | thioredoxin interacting protein | 0.0671264 |
| EZR | ezrin | 0.0625651 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0606829 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0606544 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0599156 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0564556 |
| PTMA | prothymosin, alpha | 0.0559527 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.055163 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0542313 |
| EMP1 | epithelial membrane protein 1 | 0.0492552 |
| RNF145 | ring finger protein 145 | 0.0485212 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0469183 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0465716 |
| TMSB10 | thymosin beta 10 | 0.0460518 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0456402 |
| WDR45B | WD repeat domain 45B | 0.0440285 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0433317 |
| GDF15 | growth differentiation factor 15 | 0.0426752 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0421209 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0417695 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0407192 |
| MXD1 | MAX dimerization protein 1 | 0.0395427 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0383682 |
| RAB6A | RAB6A, member RAS oncogene family | 0.038194 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0378941 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0375778 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0375694 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0370903 |
| VCL | vinculin | 0.0369412 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0362107 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0353684 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0350979 |
| FAM13A | family with sequence similarity 13, member A | 0.0350856 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0349897 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0348865 |
| S100A6 | S100 calcium binding protein A6 | 0.0348698 |
| ANXA1 | annexin A1 | 0.0346045 |
| FNBP1L | formin binding protein 1-like | 0.0344333 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0341026 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0341013 |
| TPM4 | tropomyosin 4 | 0.0336316 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0333451 |
| SLMAP | sarcolemma associated protein | 0.0333332 |
| LAMA4 | laminin, alpha 4 | 0.0331823 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0326776 |
| NUP58 | nucleoporin 58 | 0.0309273 |
| RCOR1 | REST corepressor 1 | 0.0301446 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.0300813 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0300744 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0300401 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0297377 |
| USP3 | ubiquitin specific peptidase 3 | 0.0296703 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0295011 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0292628 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0291871 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0290536 |
| IER3 | immediate early response 3 | 0.0286552 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0283277 |
| CALB1 | calbindin 1, 28kDa | 0.0280943 |
| LRRC1 | leucine rich repeat containing 1 | 0.0279401 |
| FERMT1 | fermitin family member 1 | 0.0278476 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.0277972 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0272557 |
| ITGA6 | integrin, alpha 6 | 0.0271254 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0269579 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.026792 |
| FLNB | filamin B, beta | 0.0266397 |
| JUN | jun proto-oncogene | 0.026194 |
| NPSR1 | neuropeptide S receptor 1 | 0.0261541 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0260855 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0259557 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0259208 |
| KRT8 | keratin 8, type II | 0.025913 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0257532 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0246168 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0246011 |
| IGFL2 | IGF-like family member 2 | 0.0244913 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.0244599 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0243856 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0243242 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0241916 |
| FDPS | farnesyl diphosphate synthase | 0.0239568 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0232542 |
| MATR3 | matrin 3 | 0.0227461 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0227034 |
| TMEM41B | transmembrane protein 41B | 0.0224259 |
| UBC | ubiquitin C | 0.022419 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0222991 |
| CD9 | CD9 molecule | 0.0222678 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0221882 |
| LIPH | lipase, member H | 0.0221376 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0220844 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0220713 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0220251 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0216614 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0213509 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.201476 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.173024 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.145284 |
| RPS2 | ribosomal protein S2 | -0.109954 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0940545 |
| RPS6 | ribosomal protein S6 | -0.0813273 |
| GPHN | gephyrin | -0.0714909 |
| CADPS | Ca++-dependent secretion activator | -0.0695954 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0658221 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0585543 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0544338 |
| DSPP | dentin sialophosphoprotein | -0.0520287 |
| CD44 | CD44 molecule (Indian blood group) | -0.0505514 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0497041 |
| GOLGB1 | golgin B1 | -0.0464595 |
| NEBL | nebulette | -0.0449918 |
| TNS4 | tensin 4 | -0.0449159 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0444944 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0443553 |
| RPLP1 | ribosomal protein, large, P1 | -0.0439879 |
| RPL9 | ribosomal protein L9 | -0.042131 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.040182 |
| RPL26 | ribosomal protein L26 | -0.040086 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0395776 |
| FHIT | fragile histidine triad | -0.038792 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0383242 |
| PRELID2 | PRELI domain containing 2 | -0.0375094 |
| CALR | calreticulin | -0.037055 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0365439 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0363544 |
| ATXN1 | ataxin 1 | -0.0363123 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0357283 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0356595 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0348936 |
| DSG2 | desmoglein 2 | -0.0347083 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0345426 |
| PDZD8 | PDZ domain containing 8 | -0.0343559 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0341376 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0338302 |
| RPL19 | ribosomal protein L19 | -0.0335426 |
| RNF43 | ring finger protein 43 | -0.0334282 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0331994 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0331933 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0330748 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0326276 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0325834 |
| CENPF | centromere protein F, 350/400kDa | -0.032446 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0322544 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0318656 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0317597 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0309927 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0308908 |
| RPS8 | ribosomal protein S8 | -0.0308623 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0302439 |
| SSR1 | signal sequence receptor, alpha | -0.0301311 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0300585 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0299964 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0297422 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0297371 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0296753 |
| RPL12 | ribosomal protein L12 | -0.0296012 |
| NRXN3 | neurexin 3 | -0.0294973 |
| PCDHB16 | protocadherin beta 16 | -0.0288991 |
| FOXP1 | forkhead box P1 | -0.0287096 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0285941 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0283138 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | -0.0277134 |
| RPL7 | ribosomal protein L7 | -0.0273062 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0272389 |
| RPS12 | ribosomal protein S12 | -0.0269345 |
| RPLP2 | ribosomal protein, large, P2 | -0.0268876 |
| PTEN | phosphatase and tensin homolog | -0.0268382 |
| RPS27A | ribosomal protein S27a | -0.0264812 |
| USP47 | ubiquitin specific peptidase 47 | -0.0264803 |
| VEGFA | vascular endothelial growth factor A | -0.0263596 |
| RPL3 | ribosomal protein L3 | -0.0262692 |
| SMYD3 | SET and MYND domain containing 3 | -0.0262218 |
| ASPH | aspartate beta-hydroxylase | -0.0261914 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0260427 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0260028 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0258363 |
| FNDC3B | fibronectin type III domain containing 3B | -0.025802 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0257955 |
| ZNRF3 | zinc and ring finger 3 | -0.0257371 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0256225 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0255658 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0255215 |
| PIGR | polymeric immunoglobulin receptor | -0.0251713 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.024979 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0249729 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0249709 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0248718 |
| TRIM2 | tripartite motif containing 2 | -0.0248281 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0246623 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0245919 |
| RPL37A | ribosomal protein L37a | -0.0245086 |
| RAD51B | RAD51 paralog B | -0.0244777 |
| MUC13 | mucin 13, cell surface associated | -0.0243873 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0243687 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0243571 |
