| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaprozin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.117026 |
| PTMA | prothymosin, alpha | 0.0901021 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0686246 |
| PCBP2 | poly(rC) binding protein 2 | 0.0558156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0478318 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0410671 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0408729 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0406698 |
| ENO1 | enolase 1, (alpha) | 0.0367841 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0355954 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0354583 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0348387 |
| PLIN2 | perilipin 2 | 0.0345398 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0342417 |
| B2M | beta-2-microglobulin | 0.033797 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0337 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0329543 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0314536 |
| HMGA1 | high mobility group AT-hook 1 | 0.0311789 |
| FNIP1 | folliculin interacting protein 1 | 0.0299936 |
| MSN | moesin | 0.0292946 |
| RPS12 | ribosomal protein S12 | 0.0289776 |
| MYADM | myeloid-associated differentiation marker | 0.0286645 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0285491 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0283881 |
| HLA-B | major histocompatibility complex, class I, B | 0.0273488 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0268265 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0266199 |
| CCNL1 | cyclin L1 | 0.0263899 |
| SLK | STE20-like kinase | 0.0262758 |
| PRELID2 | PRELI domain containing 2 | 0.02584 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0256924 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0252505 |
| EFNA5 | ephrin-A5 | 0.0251645 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0251181 |
| PFN1 | profilin 1 | 0.0244378 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0243407 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0243046 |
| HLA-A | major histocompatibility complex, class I, A | 0.0241296 |
| PCDH1 | protocadherin 1 | 0.0240565 |
| ARF6 | ADP-ribosylation factor 6 | 0.0237643 |
| FOSL1 | FOS-like antigen 1 | 0.0234714 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0234058 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0230192 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0229534 |
| TPM3 | tropomyosin 3 | 0.0227646 |
| PKM | pyruvate kinase, muscle | 0.0227071 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0224321 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0222058 |
| HDGF | hepatoma-derived growth factor | 0.0220572 |
| WASF2 | WAS protein family, member 2 | 0.021582 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0212826 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0212228 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0210864 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0210665 |
| SET | SET nuclear proto-oncogene | 0.0207138 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0204047 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0201646 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0194983 |
| XPO1 | exportin 1 | 0.0194886 |
| CDK19 | cyclin-dependent kinase 19 | 0.0191959 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0191827 |
| CD109 | CD109 molecule | 0.0191443 |
| ZNF148 | zinc finger protein 148 | 0.0191239 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0187849 |
| MATR3 | matrin 3 | 0.0185918 |
| FTL | ferritin, light polypeptide | 0.0183573 |
| UBXN4 | UBX domain protein 4 | 0.0182877 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0182805 |
| TAPBP | TAP binding protein (tapasin) | 0.0181238 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.017724 |
| EGR1 | early growth response 1 | 0.0176729 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0175014 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0174648 |
| HELZ | helicase with zinc finger | 0.0171754 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0171707 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0170067 |
| SRP54 | signal recognition particle 54kDa | 0.0170002 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0169661 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0167638 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0167614 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0165435 |
| MEF2A | myocyte enhancer factor 2A | 0.016515 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0165048 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0163112 |
| RPS14 | ribosomal protein S14 | 0.0162336 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0162109 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0161278 |
| RPL11 | ribosomal protein L11 | 0.0160647 |
| MYOF | myoferlin | 0.0157425 |
| NDRG1 | N-myc downstream regulated 1 | 0.0157218 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.015676 |
| SMIM44 | small integral membrane protein 44 | 0.0156067 |
| GOLGA4 | golgin A4 | 0.0154376 |
| YBX1 | Y box binding protein 1 | 0.0154166 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0154119 |
| AK2 | adenylate kinase 2 | 0.0153894 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0151969 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0151785 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0150505 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.266878 |
| TXNRD1 | thioredoxin reductase 1 | -0.159508 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.114843 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.108156 |
| CD44 | CD44 molecule (Indian blood group) | -0.106516 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10205 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0925676 |
| DST | dystonin | -0.0809846 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0773879 |
| AHNAK | AHNAK nucleoprotein | -0.0769539 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0689532 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0686698 |
| APP | amyloid beta (A4) precursor protein | -0.065104 |
| RUNX1 | runt-related transcription factor 1 | -0.0633777 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0625348 |
| CANX | calnexin | -0.0611538 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0589308 |
| ACTG1 | actin gamma 1 | -0.0556303 |
| RGS4 | regulator of G-protein signaling 4 | -0.0540575 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.051994 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0516881 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0507882 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0494824 |
| EMP1 | epithelial membrane protein 1 | -0.0494334 |
| HDLBP | high density lipoprotein binding protein | -0.0481506 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0478854 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0477856 |
| ZNF217 | zinc finger protein 217 | -0.0466114 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0447567 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0440175 |
| TMSB10 | thymosin beta 10 | -0.043723 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0433578 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0432422 |
| USP34 | ubiquitin specific peptidase 34 | -0.0430681 |
| KLF6 | Kruppel-like factor 6 | -0.0427346 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0422647 |
| TP63 | tumor protein p63 | -0.0418494 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0417092 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.041 |
| FMNL2 | formin-like 2 | -0.0393271 |
| EZR | ezrin | -0.0388889 |
| ARF1 | ADP-ribosylation factor 1 | -0.0388388 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.038834 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0376885 |
| BMERB1 | bMERB domain containing 1 | -0.0374279 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.036886 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0366529 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0364758 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.036362 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0359126 |
| RPL4 | ribosomal protein L4 | -0.0353079 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0348363 |
| MORF4L2 | mortality factor 4 like 2 | -0.0347511 |
| RBM39 | RNA binding motif protein 39 | -0.0330566 |
| TOP1 | topoisomerase (DNA) I | -0.0330465 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0329958 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0328655 |
| ANXA1 | annexin A1 | -0.0326608 |
| RIGI | RNA sensor RIG-I | -0.0323882 |
| HPCAL1 | hippocalcin-like 1 | -0.032244 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.031981 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0315508 |
| SPAG9 | sperm associated antigen 9 | -0.031177 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0309262 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0304345 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0303076 |
| YBX3 | Y box binding protein 3 | -0.0296599 |
| JMJD1C | jumonji domain containing 1C | -0.0296568 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0295859 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0295461 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0294439 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0294384 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0289133 |
| PGK1 | phosphoglycerate kinase 1 | -0.0284575 |
| NF1 | neurofibromin 1 | -0.0284177 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0283732 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0283215 |
| FUS | FUS RNA binding protein | -0.0282579 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0282389 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0282312 |
| RRBP1 | ribosome binding protein 1 | -0.028017 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0279691 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0279554 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0279504 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0279337 |
| CMIP | c-Maf inducing protein | -0.0278581 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.026907 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0265018 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0264343 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0261808 |
| CALR | calreticulin | -0.0261696 |
| SP100 | SP100 nuclear antigen | -0.0260413 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.025915 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0257466 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0256352 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0255145 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0251078 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0250651 |
| CUL1 | cullin 1 | -0.0247898 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0247609 |
