| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.135548 |
| PCBP2 | poly(rC) binding protein 2 | 0.119668 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.106052 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0835925 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0810204 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0758689 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0695395 |
| MEF2A | myocyte enhancer factor 2A | 0.0623374 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0619303 |
| FAM13A | family with sequence similarity 13, member A | 0.0618775 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0611302 |
| USP34 | ubiquitin specific peptidase 34 | 0.0591642 |
| NGLY1 | N-glycanase 1 | 0.0560106 |
| SETD5 | SET domain containing 5 | 0.0552526 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0494332 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0493143 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0486916 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0479615 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0471432 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0438942 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0437347 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.042721 |
| FN1 | fibronectin 1 | 0.0426776 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0422924 |
| PRELID2 | PRELI domain containing 2 | 0.0400032 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0399054 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0397786 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0387686 |
| HELZ | helicase with zinc finger | 0.0387522 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0380313 |
| DTNA | dystrobrevin, alpha | 0.0379572 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.037954 |
| MTSS1 | metastasis suppressor 1 | 0.0367752 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0366817 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0365991 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0363428 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0361178 |
| JMJD1C | jumonji domain containing 1C | 0.0355916 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0354319 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0351343 |
| CD109 | CD109 molecule | 0.0349483 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0348876 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0347224 |
| XPO1 | exportin 1 | 0.0343466 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0341821 |
| PGK1 | phosphoglycerate kinase 1 | 0.0337896 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0337356 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0336704 |
| MYO1B | myosin IB | 0.033497 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0330949 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0328536 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0327937 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0327513 |
| ATP13A3 | ATPase type 13A3 | 0.0324419 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0323941 |
| PYGL | phosphorylase, glycogen, liver | 0.0323449 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0320517 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0320078 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0315733 |
| PTK2 | protein tyrosine kinase 2 | 0.0315168 |
| ATXN1 | ataxin 1 | 0.0311607 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0311053 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0307173 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.030262 |
| STC1 | stanniocalcin 1 | 0.0302378 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0300255 |
| INSIG2 | insulin induced gene 2 | 0.0298899 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0297585 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0296293 |
| NUP58 | nucleoporin 58 | 0.0286861 |
| CA12 | carbonic anhydrase XII | 0.0286698 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0285973 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0285584 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0284877 |
| YEATS2 | YEATS domain containing 2 | 0.0280593 |
| RNF145 | ring finger protein 145 | 0.0278208 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0269191 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0267096 |
| FBXO11 | F-box protein 11 | 0.0264557 |
| SPAG9 | sperm associated antigen 9 | 0.0260884 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.026035 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.025726 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.025392 |
| NHSL1 | NHS-like 1 | 0.0253602 |
| SNX9 | sorting nexin 9 | 0.0251328 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0248751 |
| SUCO | SUN domain containing ossification factor | 0.0248167 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.024599 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0245398 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245368 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0244427 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0244171 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0241894 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0240747 |
| RUNX1 | runt-related transcription factor 1 | 0.0238334 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0238149 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0237985 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0236355 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0234542 |
| SNX13 | sorting nexin 13 | 0.0234181 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153627 |
| VIM | vimentin | -0.125643 |
| CD44 | CD44 molecule (Indian blood group) | -0.0994089 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0966129 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0726905 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0722901 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0688657 |
| RPLP1 | ribosomal protein, large, P1 | -0.0628939 |
| FTL | ferritin, light polypeptide | -0.0601664 |
| OSMR | oncostatin M receptor | -0.0577223 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0574213 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0557204 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0553292 |
| TMSB10 | thymosin beta 10 | -0.0494158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0486879 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0485187 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0466893 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0460515 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0455701 |
| KYNU | kynureninase | -0.0429694 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0420014 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0406232 |
| BPTF | bromodomain PHD finger transcription factor | -0.0391693 |
| GLCCI1 | glucocorticoid induced 1 | -0.0389304 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0387822 |
| EFNA5 | ephrin-A5 | -0.0387202 |
| HDLBP | high density lipoprotein binding protein | -0.0386432 |
| RPL34 | ribosomal protein L34 | -0.0363454 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0360639 |
| RPL19 | ribosomal protein L19 | -0.0359208 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0355936 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.035112 |
| RPS19 | ribosomal protein S19 | -0.0350645 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0346371 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.034015 |
| RPL23 | ribosomal protein L23 | -0.0338735 |
| AOPEP | aminopeptidase O (putative) | -0.0328282 |
| MEIS1 | Meis homeobox 1 | -0.032035 |
| RPL35A | ribosomal protein L35a | -0.0300837 |
| NTN4 | netrin 4 | -0.0298962 |
| NRP1 | neuropilin 1 | -0.0290402 |
| RPS21 | ribosomal protein S21 | -0.0290298 |
| RPS8 | ribosomal protein S8 | -0.0289609 |
| MT2A | metallothionein 2A | -0.0289469 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285694 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0284993 |
| IER3 | immediate early response 3 | -0.0284134 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0282757 |
| ETV6 | ets variant 6 | -0.0281205 |
| RAD51B | RAD51 paralog B | -0.027654 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0275058 |
| RPL12 | ribosomal protein L12 | -0.0274126 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0269885 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269671 |
| GNAS | GNAS complex locus | -0.0261766 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0260514 |
| SYNJ2 | synaptojanin 2 | -0.0258737 |
| RPL32 | ribosomal protein L32 | -0.0258577 |
| LAMA4 | laminin, alpha 4 | -0.0257106 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0251504 |
| RPS27 | ribosomal protein S27 | -0.0251484 |
| GPC6 | glypican 6 | -0.0250748 |
| KIAA1217 | KIAA1217 | -0.0246388 |
| MYO9A | myosin IXA | -0.0246312 |
| RPS24 | ribosomal protein S24 | -0.024511 |
| AHNAK | AHNAK nucleoprotein | -0.0241694 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.024151 |
| TMSB4X | thymosin beta 4, X-linked | -0.0240965 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0239487 |
| RPS6 | ribosomal protein S6 | -0.0238127 |
| MAP1B | microtubule-associated protein 1B | -0.0233707 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0232741 |
| KSR1 | kinase suppressor of ras 1 | -0.0229946 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0229933 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0229819 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0229697 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0229089 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0227545 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0226772 |
| FRMD4A | FERM domain containing 4A | -0.0224097 |
| ZFP91 | ZFP91 zinc finger protein | -0.0223023 |
| SRGN | serglycin | -0.0222931 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0221574 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0220202 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0218068 |
| ACTG1 | actin gamma 1 | -0.0214709 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0212958 |
| PHF14 | PHD finger protein 14 | -0.0211843 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0208774 |
| PCNX4 | pecanex 4 | -0.020815 |
| YME1L1 | YME1-like 1 ATPase | -0.0207774 |
| RPS5 | ribosomal protein S5 | -0.0205257 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0204929 |
| RPLP2 | ribosomal protein, large, P2 | -0.0203493 |
| IL1R1 | interleukin 1 receptor, type I | -0.0201453 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0199262 |
| ATF6 | activating transcription factor 6 | -0.0198936 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0198575 |
| LDHA | lactate dehydrogenase A | -0.0198123 |
| EGR1 | early growth response 1 | -0.0198095 |
