| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.131384 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.107382 |
| TMSB10 | thymosin beta 10 | 0.0952948 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0931424 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0867566 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0849896 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0848958 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0811451 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0803243 |
| S100A6 | S100 calcium binding protein A6 | 0.0748383 |
| TFG | TRK-fused gene | 0.0736556 |
| RPS25 | ribosomal protein S25 | 0.0715882 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0714844 |
| FN1 | fibronectin 1 | 0.0701409 |
| POTEF | POTE ankyrin domain family, member F | 0.0679757 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0676009 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0662997 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0643403 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0627714 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.05815 |
| CDK13 | cyclin-dependent kinase 13 | 0.0563656 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0555522 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.054391 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0538092 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0527527 |
| ZNF292 | zinc finger protein 292 | 0.0527201 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0521786 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0521725 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0520997 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0517107 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0514332 |
| RPL9 | ribosomal protein L9 | 0.0506006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0503097 |
| PRELID2 | PRELI domain containing 2 | 0.049701 |
| DOCK7 | dedicator of cytokinesis 7 | 0.0490299 |
| TLK2 | tousled-like kinase 2 | 0.0490212 |
| TMSB4X | thymosin beta 4, X-linked | 0.048 |
| SLMAP | sarcolemma associated protein | 0.0477616 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0473915 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0473807 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0465398 |
| CD109 | CD109 molecule | 0.0464181 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0461708 |
| RPS8 | ribosomal protein S8 | 0.0461243 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.045456 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0453321 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.045243 |
| CALD1 | caldesmon 1 | 0.0450112 |
| GOLGA4 | golgin A4 | 0.0449402 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0448727 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0447775 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0447773 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0446135 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0445354 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0443369 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.04403 |
| PGK1 | phosphoglycerate kinase 1 | 0.0436387 |
| RNF145 | ring finger protein 145 | 0.0433388 |
| MED13 | mediator complex subunit 13 | 0.0433153 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0429901 |
| RPL15 | ribosomal protein L15 | 0.0427163 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0426433 |
| COG5 | component of oligomeric golgi complex 5 | 0.0413666 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0412353 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0411845 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0409802 |
| ENAH | enabled homolog (Drosophila) | 0.0407091 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0406394 |
| FAM168A | family with sequence similarity 168, member A | 0.0404698 |
| RBM39 | RNA binding motif protein 39 | 0.0404013 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0402356 |
| TRIM33 | tripartite motif containing 33 | 0.0398108 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0394194 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0390497 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0390291 |
| TNPO3 | transportin 3 | 0.0389763 |
| NAV1 | neuron navigator 1 | 0.0389639 |
| QKI | QKI, KH domain containing, RNA binding | 0.0383766 |
| RBM25 | RNA binding motif protein 25 | 0.0383001 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0376735 |
| NPAS2 | neuronal PAS domain protein 2 | 0.037415 |
| TPD52 | tumor protein D52 | 0.0374133 |
| VMP1 | vacuole membrane protein 1 | 0.037211 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.037146 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.037089 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0370563 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0370551 |
| MT2A | metallothionein 2A | 0.0370195 |
| TPI1 | triosephosphate isomerase 1 | 0.0368115 |
| YEATS2 | YEATS domain containing 2 | 0.0366023 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0364417 |
| USP3 | ubiquitin specific peptidase 3 | 0.0363956 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0363551 |
| FAM222B | family with sequence similarity 222, member B | 0.0362117 |
| FNBP1 | formin binding protein 1 | 0.0360183 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0359444 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0358601 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0358095 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0353721 |
| SLTM | SAFB-like, transcription modulator | 0.0352346 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125011 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.11814 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.110194 |
| MXD1 | MAX dimerization protein 1 | -0.0888374 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0884197 |
| MYO1E | myosin IE | -0.0881146 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0867855 |
| LMO7 | LIM domain 7 | -0.0865785 |
| KRT17 | keratin 17, type I | -0.0848157 |
| IGF2 | insulin-like growth factor 2 | -0.0820818 |
| KYNU | kynureninase | -0.0767408 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0745448 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0729178 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0722367 |
| LAMB3 | laminin, beta 3 | -0.0714965 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0676981 |
| CANX | calnexin | -0.0629199 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0627583 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.061442 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0610482 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0607277 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0605945 |
| RIGI | RNA sensor RIG-I | -0.0575588 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0567991 |
| ANXA1 | annexin A1 | -0.0564644 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.05637 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0563362 |
| ATOSA | atos homolog A | -0.054156 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0534158 |
| ANO6 | anoctamin 6 | -0.0531238 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0527264 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.052394 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0514507 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0509465 |
| LAMC2 | laminin, gamma 2 | -0.0506086 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0503454 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0493937 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0482599 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0481765 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0468986 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.046423 |
| RORA | RAR-related orphan receptor A | -0.0459284 |
| FOXP1 | forkhead box P1 | -0.0458065 |
| TJP1 | tight junction protein 1 | -0.0447616 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0444116 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0437597 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0426521 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0426369 |
| STC1 | stanniocalcin 1 | -0.0424518 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0420102 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0419146 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0417886 |
| S100A10 | S100 calcium binding protein A10 | -0.0415509 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0407514 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0404912 |
| SDC4 | syndecan 4 | -0.0404781 |
| SP100 | SP100 nuclear antigen | -0.0397132 |
| RPS24 | ribosomal protein S24 | -0.0395325 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0390991 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0390699 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.038968 |
| CD44 | CD44 molecule (Indian blood group) | -0.0387763 |
| MORF4L2 | mortality factor 4 like 2 | -0.0385174 |
| RPL34 | ribosomal protein L34 | -0.038325 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0378346 |
| H3-3B | H3.3 histone B | -0.0377609 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0376849 |
| SDCBP | syndecan binding protein (syntenin) | -0.0376357 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.037428 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0371837 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0369814 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0368825 |
| ABHD17C | abhydrolase domain containing 17C | -0.0364841 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0359253 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0358173 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0357493 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0357353 |
| SCFD1 | sec1 family domain containing 1 | -0.0355581 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0355249 |
| IER3 | immediate early response 3 | -0.0352901 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0351304 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0350717 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0350569 |
| RPL35A | ribosomal protein L35a | -0.0350405 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0350195 |
| DSPP | dentin sialophosphoprotein | -0.0345167 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.034174 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0339221 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0338544 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0338348 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0338008 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0337962 |
| FAM107B | family with sequence similarity 107, member B | -0.0336862 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0332703 |
| ADM | adrenomedullin | -0.0332162 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0325777 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0321941 |
| SEPTIN9 | septin 9 | -0.0321447 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0316135 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0314157 |
