| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaprozin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.195076 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.18887 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.185743 |
| NDRG1 | N-myc downstream regulated 1 | 0.165193 |
| SPAG9 | sperm associated antigen 9 | 0.148492 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.141161 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.126836 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.118075 |
| VIM | vimentin | 0.110364 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0940914 |
| COPA | coatomer protein complex, subunit alpha | 0.0899813 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0826046 |
| CTBP2 | C-terminal binding protein 2 | 0.0792239 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.078402 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0759527 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0757862 |
| PTMA | prothymosin, alpha | 0.0755388 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0708393 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0707325 |
| RAB10 | RAB10, member RAS oncogene family | 0.0677283 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.066463 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0660594 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0654659 |
| MED13L | mediator complex subunit 13-like | 0.0590311 |
| RTN4 | reticulon 4 | 0.057744 |
| ANXA2 | annexin A2 | 0.0572964 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0564062 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0555093 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0545484 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0537564 |
| CANX | calnexin | 0.0533573 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0514786 |
| ENO1 | enolase 1, (alpha) | 0.0511932 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0510227 |
| RNF145 | ring finger protein 145 | 0.0505879 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0502684 |
| B2M | beta-2-microglobulin | 0.0495335 |
| TXNRD1 | thioredoxin reductase 1 | 0.049104 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0482885 |
| FNIP1 | folliculin interacting protein 1 | 0.048128 |
| PTK2 | protein tyrosine kinase 2 | 0.0474601 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0469553 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0457016 |
| GPC6 | glypican 6 | 0.0446648 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0427523 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0416325 |
| FAM13A | family with sequence similarity 13, member A | 0.040868 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0378968 |
| SYAP1 | synapse associated protein 1 | 0.037605 |
| HELZ | helicase with zinc finger | 0.0372469 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0369495 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0360763 |
| ERBIN | erbb2 interacting protein | 0.0358718 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0353646 |
| VMP1 | vacuole membrane protein 1 | 0.0328261 |
| JMJD1C | jumonji domain containing 1C | 0.031444 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0306685 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0304129 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0295345 |
| ANKRD12 | ankyrin repeat domain 12 | 0.029331 |
| RPL15 | ribosomal protein L15 | 0.0279205 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0278847 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271499 |
| SQSTM1 | sequestosome 1 | 0.0266046 |
| FAM162A | family with sequence similarity 162, member A | 0.0264234 |
| FBXO11 | F-box protein 11 | 0.0257709 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0249575 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0249285 |
| RORA | RAR-related orphan receptor A | 0.0245279 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240644 |
| NF1 | neurofibromin 1 | 0.0236696 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0226902 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0223791 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0218845 |
| COG5 | component of oligomeric golgi complex 5 | 0.0217988 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0204096 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0195684 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0170633 |
| RUNX1 | runt-related transcription factor 1 | 0.016668 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0151928 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0145241 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0142622 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0139118 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0132641 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.011876 |
| H3-3B | H3.3 histone B | 0.0116752 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0110502 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0103789 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0103061 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0100006 |
| RPLP0 | ribosomal protein, large, P0 | 0.00984431 |
| MORF4L2 | mortality factor 4 like 2 | 0.00961046 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00912457 |
| AFDN | afadin, adherens junction formation factor | 0.00740031 |
| RPS6 | ribosomal protein S6 | 0.00681804 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00678461 |
| PUM2 | pumilio RNA-binding family member 2 | 0.00662286 |
| PGK1 | phosphoglycerate kinase 1 | 0.00660714 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00607151 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00597394 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.147714 |
| DOCK4 | dedicator of cytokinesis 4 | -0.121872 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.112652 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0997818 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0964717 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0949895 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.085967 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0852779 |
| VCL | vinculin | -0.0844455 |
| FOXP1 | forkhead box P1 | -0.0819056 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0810905 |
| VGF | VGF nerve growth factor inducible | -0.0805515 |
| PDE10A | phosphodiesterase 10A | -0.0802139 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0753408 |
| RPS8 | ribosomal protein S8 | -0.073729 |
| SMYD3 | SET and MYND domain containing 3 | -0.0723105 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0719726 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0708665 |
| USP34 | ubiquitin specific peptidase 34 | -0.0684359 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0680675 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0618827 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0612785 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0609272 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0601951 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0597494 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0593835 |
| RPS12 | ribosomal protein S12 | -0.0583525 |
| MT2A | metallothionein 2A | -0.053256 |
| RPL35A | ribosomal protein L35a | -0.05323 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0509893 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0500073 |
| ACTG1 | actin gamma 1 | -0.0486343 |
| RPL26 | ribosomal protein L26 | -0.0486131 |
| ATF4 | activating transcription factor 4 | -0.047302 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0467669 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0467044 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0456731 |
| POTEF | POTE ankyrin domain family, member F | -0.0455187 |
| RACK1 | receptor for activated C kinase 1 | -0.0451394 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0442104 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0436596 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0425282 |
| ZNF292 | zinc finger protein 292 | -0.0423692 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0422639 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0416888 |
| DST | dystonin | -0.040448 |
| MYO1E | myosin IE | -0.0393535 |
| GOLGA4 | golgin A4 | -0.0366917 |
| RPL31 | ribosomal protein L31 | -0.0354916 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0342454 |
| IGF2 | insulin-like growth factor 2 | -0.0316261 |
| FN1 | fibronectin 1 | -0.0316231 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0316121 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0303938 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0303765 |
| TMSB10 | thymosin beta 10 | -0.0303387 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0299887 |
| TMEM123 | transmembrane protein 123 | -0.0298421 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0291866 |
| EFNA5 | ephrin-A5 | -0.0290636 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0289665 |
| OGA | O-GlcNAcase | -0.0286724 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0277367 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0277017 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0267823 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0263715 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.025482 |
| RPS27A | ribosomal protein S27a | -0.0236207 |
| PKM | pyruvate kinase, muscle | -0.0236059 |
| SBF2 | SET binding factor 2 | -0.0227273 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0225738 |
| STC1 | stanniocalcin 1 | -0.0223018 |
| RPS19 | ribosomal protein S19 | -0.021552 |
| USP3 | ubiquitin specific peptidase 3 | -0.020349 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0190916 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0186163 |
| MYOF | myoferlin | -0.0174976 |
| RPS3 | ribosomal protein S3 | -0.0172861 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0156881 |
| RPL19 | ribosomal protein L19 | -0.0147975 |
| FTL | ferritin, light polypeptide | -0.0146218 |
| FLNB | filamin B, beta | -0.0143178 |
| RBM39 | RNA binding motif protein 39 | -0.0135093 |
| RPL37A | ribosomal protein L37a | -0.0134192 |
| RPS16 | ribosomal protein S16 | -0.0131691 |
| SCFD1 | sec1 family domain containing 1 | -0.013052 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.012823 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0121711 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0116524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0115938 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0110385 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0100653 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00997683 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00989197 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.00969865 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0096366 |
| DSCAM | Down syndrome cell adhesion molecule | -0.00850303 |
| RPL11 | ribosomal protein L11 | -0.00814846 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.00758885 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00524689 |
