| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Oxaprozin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.251874 |
| PTMA | prothymosin, alpha | 0.11926 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0938391 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0886949 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0841971 |
| TMSB4X | thymosin beta 4, X-linked | 0.0784486 |
| LDHA | lactate dehydrogenase A | 0.0744574 |
| GOLGA4 | golgin A4 | 0.0664892 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0607427 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0606633 |
| PGK1 | phosphoglycerate kinase 1 | 0.0578962 |
| S100A6 | S100 calcium binding protein A6 | 0.0557916 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0551438 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0530431 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0514506 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0510805 |
| ENO1 | enolase 1, (alpha) | 0.0493258 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0476481 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0460239 |
| TXNRD1 | thioredoxin reductase 1 | 0.0458392 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0451433 |
| JMJD1C | jumonji domain containing 1C | 0.0448599 |
| VCL | vinculin | 0.0433124 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0428336 |
| ZNF292 | zinc finger protein 292 | 0.0426687 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0426544 |
| ACTG1 | actin gamma 1 | 0.0421386 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0409975 |
| RPS6 | ribosomal protein S6 | 0.0405158 |
| PKM | pyruvate kinase, muscle | 0.0384018 |
| LOC112694756 | uncharaterized LOC112694756 | 0.038023 |
| RPLP0 | ribosomal protein, large, P0 | 0.0365625 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0361078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.035716 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0353468 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0352633 |
| DSTN | destrin (actin depolymerizing factor) | 0.03524 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0335859 |
| TXNIP | thioredoxin interacting protein | 0.0335854 |
| GPHN | gephyrin | 0.033099 |
| EZR | ezrin | 0.0327717 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0318758 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0313664 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0312053 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0311726 |
| SETD5 | SET domain containing 5 | 0.0305234 |
| SBF2 | SET binding factor 2 | 0.0304784 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0300916 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0293393 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0286361 |
| RNF145 | ring finger protein 145 | 0.0283886 |
| UBC | ubiquitin C | 0.0282943 |
| COG5 | component of oligomeric golgi complex 5 | 0.0280051 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0278303 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0277824 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0275174 |
| SLC38A2 | solute carrier family 38, member 2 | 0.026883 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0265682 |
| AHNAK | AHNAK nucleoprotein | 0.0265024 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0263555 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0261105 |
| RBM25 | RNA binding motif protein 25 | 0.0258244 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0257101 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0254683 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0252423 |
| TMEM41B | transmembrane protein 41B | 0.0251645 |
| NKTR | natural killer cell triggering receptor | 0.0251451 |
| WDR43 | WD repeat domain 43 | 0.0249522 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0245416 |
| EFNA5 | ephrin-A5 | 0.024453 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0244276 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0242238 |
| DUSP4 | dual specificity phosphatase 4 | 0.0241352 |
| USP34 | ubiquitin specific peptidase 34 | 0.0240399 |
| RBM39 | RNA binding motif protein 39 | 0.0240097 |
| SET | SET nuclear proto-oncogene | 0.0239905 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0239315 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0237904 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0236901 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0236739 |
| DIAPH2 | diaphanous-related formin 2 | 0.023248 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230022 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0229821 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0228937 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0228736 |
| VMP1 | vacuole membrane protein 1 | 0.0228234 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.022679 |
| RTN4 | reticulon 4 | 0.0226009 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.022482 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0224526 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0223908 |
| PFN1 | profilin 1 | 0.022373 |
| NBAS | neuroblastoma amplified sequence | 0.0220706 |
| MTDH | metadherin | 0.0219821 |
| EVI5 | ecotropic viral integration site 5 | 0.0216932 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0216083 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0215988 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0215173 |
| B2M | beta-2-microglobulin | 0.0214819 |
| HM13 | histocompatibility (minor) 13 | 0.0214631 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAV2 | neuron navigator 2 | -0.0463846 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0273866 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0240012 |
| FOXP1 | forkhead box P1 | -0.0219458 |
| INTS6 | integrator complex subunit 6 | -0.0214213 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0210345 |
| GLI3 | GLI family zinc finger 3 | -0.0207931 |
| MYO5C | myosin VC | -0.0203753 |
| CENPE | centromere protein E, 312kDa | -0.020319 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0196584 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0191359 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0191102 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0186293 |
| DIAPH3 | diaphanous-related formin 3 | -0.0183814 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0177516 |
| TMSB10 | thymosin beta 10 | -0.0175785 |
| RCOR1 | REST corepressor 1 | -0.0170779 |
| GSE1 | Gse1 coiled-coil protein | -0.0164966 |
| PDE7B | phosphodiesterase 7B | -0.0164702 |
| UBAP2 | ubiquitin associated protein 2 | -0.016452 |
| CENPF | centromere protein F, 350/400kDa | -0.0162442 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.015569 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0152764 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0152091 |
| MKI67 | marker of proliferation Ki-67 | -0.0151188 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0140551 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0138643 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0135016 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0131947 |
| SACK1D | scaffolding CK1 anchoring protein D | -0.0131767 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0128687 |
| TJP1 | tight junction protein 1 | -0.0127116 |
| LMO7 | LIM domain 7 | -0.0126488 |
| VIM | vimentin | -0.0124926 |
| DUSP6 | dual specificity phosphatase 6 | -0.0121596 |
| POLH | polymerase (DNA directed), eta | -0.012058 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0119326 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0119014 |
| KIF18B | kinesin family member 18B | -0.0119007 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0115445 |
| AEBP2 | AE binding protein 2 | -0.0112084 |
| CEP112 | centrosomal protein 112kDa | -0.0111706 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0107909 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0107816 |
| RRM2 | ribonucleotide reductase M2 | -0.010761 |
| ANLN | anillin, actin binding protein | -0.0107176 |
| RAD51B | RAD51 paralog B | -0.0106191 |
| HMGB1 | high mobility group box 1 | -0.0105767 |
| APLF | aprataxin and PNKP like factor | -0.0104896 |
| TPX2 | TPX2, microtubule-associated | -0.010426 |
| KIF11 | kinesin family member 11 | -0.0103794 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0103689 |
| WWOX | WW domain containing oxidoreductase | -0.010343 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0103106 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0102236 |
| SGMS2 | sphingomyelin synthase 2 | -0.0102216 |
| LAMA4 | laminin, alpha 4 | -0.0102037 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0100587 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0100326 |
| BCL2 | B-cell CLL/lymphoma 2 | -0.0100087 |
| DNMBP | dynamin binding protein | -0.0099362 |
| COX7C | cytochrome c oxidase subunit VIIc | -0.00993341 |
| HMGB2 | high mobility group box 2 | -0.00979552 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00978742 |
| LACTB | lactamase, beta | -0.0097766 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0097713 |
| KIF4A | kinesin family member 4A | -0.00964523 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.00952508 |
| BMP10 | bone morphogenetic protein 10 | -0.00939027 |
| GLI2 | GLI family zinc finger 2 | -0.00930398 |
| RPL23 | ribosomal protein L23 | -0.00927715 |
| FANCI | Fanconi anemia, complementation group I | -0.00922935 |
| FER1L6 | fer-1-like family member 6 | -0.00920257 |
| SOGA1 | suppressor of glucose, autophagy associated 1 | -0.0091608 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0091463 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00914321 |
| CEP128 | centrosomal protein 128kDa | -0.00901059 |
| NOCT | nocturnin | -0.00897861 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.00895168 |
| DHFR | dihydrofolate reductase | -0.00890135 |
| DEPDC1B | DEP domain containing 1B | -0.00889148 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0088029 |
| EXOC4 | exocyst complex component 4 | -0.00878829 |
| MELTF | melanotransferrin | -0.00877079 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.00876971 |
| KIF15 | kinesin family member 15 | -0.0086846 |
| CDK1 | cyclin-dependent kinase 1 | -0.00849615 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.00849498 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.00835839 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00834281 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.00832926 |
| MELK | maternal embryonic leucine zipper kinase | -0.00830828 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0082878 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.00822354 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.00819978 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -0.00819149 |
| FN1 | fibronectin 1 | -0.00815224 |
| EMP1 | epithelial membrane protein 1 | -0.00814475 |
| CENPK | centromere protein K | -0.00814372 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.00813387 |
