| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.146127 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.143308 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.143236 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.140885 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.127118 |
| PDE10A | phosphodiesterase 10A | 0.123786 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.112373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0995817 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0928472 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0919762 |
| LDHA | lactate dehydrogenase A | 0.090104 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0847919 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0844119 |
| FNIP1 | folliculin interacting protein 1 | 0.0836386 |
| NAV2 | neuron navigator 2 | 0.0823914 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0811115 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0776762 |
| HDAC9 | histone deacetylase 9 | 0.0746346 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0730783 |
| RND3 | Rho family GTPase 3 | 0.0729208 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0707903 |
| VEGFA | vascular endothelial growth factor A | 0.0706552 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0706117 |
| PLIN2 | perilipin 2 | 0.0702059 |
| ADM | adrenomedullin | 0.0696007 |
| FLNB | filamin B, beta | 0.0677496 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0665878 |
| MYOF | myoferlin | 0.065577 |
| CD44 | CD44 molecule (Indian blood group) | 0.0621989 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0596801 |
| LOXL2 | lysyl oxidase-like 2 | 0.0589998 |
| NGLY1 | N-glycanase 1 | 0.0589553 |
| MMP12 | matrix metallopeptidase 12 | 0.0587904 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0554825 |
| CDK19 | cyclin-dependent kinase 19 | 0.0551253 |
| PGK1 | phosphoglycerate kinase 1 | 0.0546067 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.054148 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0534072 |
| VIM | vimentin | 0.0533598 |
| FMNL2 | formin-like 2 | 0.0508376 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0503719 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0488781 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0473209 |
| HLA-A | major histocompatibility complex, class I, A | 0.046478 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0464342 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0463423 |
| STC1 | stanniocalcin 1 | 0.0459246 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0454506 |
| ARFGEF3 | ARFGEF family member 3 | 0.0451963 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0451309 |
| ATXN1 | ataxin 1 | 0.0443049 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0440297 |
| DIAPH2 | diaphanous-related formin 2 | 0.0432818 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0431864 |
| CDCP1 | CUB domain containing protein 1 | 0.0424026 |
| ATP13A3 | ATPase type 13A3 | 0.0416663 |
| RAI14 | retinoic acid induced 14 | 0.0415612 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.041231 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0409919 |
| USP37 | ubiquitin specific peptidase 37 | 0.0406017 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0405444 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.040386 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0401422 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.040033 |
| PCBP3 | poly(rC) binding protein 3 | 0.0390707 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0375834 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.037105 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0370621 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370195 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0370141 |
| SQSTM1 | sequestosome 1 | 0.036889 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0367801 |
| SFTPA2 | surfactant protein A2 | 0.0365639 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0362756 |
| CDH13 | cadherin 13 | 0.0360322 |
| CEP250 | centrosomal protein 250kDa | 0.0360314 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0357699 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.035745 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0356577 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0354711 |
| DST | dystonin | 0.0354348 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0354315 |
| RUNX1 | runt-related transcription factor 1 | 0.0351498 |
| MSN | moesin | 0.0351018 |
| AFDN | afadin, adherens junction formation factor | 0.0350061 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0347301 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.034603 |
| HMGA2 | high mobility group AT-hook 2 | 0.0336477 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033489 |
| FAM219A | family with sequence similarity 219, member A | 0.0334845 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332304 |
| TNS3 | tensin 3 | 0.0331322 |
| LOX | lysyl oxidase | 0.0330192 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0329105 |
| VMP1 | vacuole membrane protein 1 | 0.0328307 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0326753 |
| FOXO3 | forkhead box O3 | 0.0326278 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0323026 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0321331 |
| STC2 | stanniocalcin 2 | 0.0320182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0944279 |
| RPS24 | ribosomal protein S24 | -0.0934027 |
| BICC1 | BicC family RNA binding protein 1 | -0.08159 |
| TMSB10 | thymosin beta 10 | -0.0787109 |
| FTL | ferritin, light polypeptide | -0.0742796 |
| MT2A | metallothionein 2A | -0.0741913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0698514 |
| RPS6 | ribosomal protein S6 | -0.0654218 |
| IER3 | immediate early response 3 | -0.0588729 |
| RPL35A | ribosomal protein L35a | -0.050245 |
| RPLP2 | ribosomal protein, large, P2 | -0.0498872 |
| PTMA | prothymosin, alpha | -0.04837 |
| RPL9 | ribosomal protein L9 | -0.04827 |
| RPL36 | ribosomal protein L36 | -0.0480094 |
| RPL32 | ribosomal protein L32 | -0.0461191 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0456959 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0456505 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0445191 |
| WTAP | Wilms tumor 1 associated protein | -0.0442069 |
| RPL23 | ribosomal protein L23 | -0.0431688 |
| THBS1 | thrombospondin 1 | -0.0426509 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0419677 |
| RPL34 | ribosomal protein L34 | -0.0410658 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0409286 |
| RPS3 | ribosomal protein S3 | -0.0408831 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0400369 |
| RPS8 | ribosomal protein S8 | -0.0397594 |
| RPS19 | ribosomal protein S19 | -0.0382886 |
| HMGB1 | high mobility group box 1 | -0.0377749 |
| RPL12 | ribosomal protein L12 | -0.0376729 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0373452 |
| RPL19 | ribosomal protein L19 | -0.0368025 |
| POTEF | POTE ankyrin domain family, member F | -0.0357695 |
| ACTG1 | actin gamma 1 | -0.0354027 |
| SRGN | serglycin | -0.0353856 |
| KLF6 | Kruppel-like factor 6 | -0.0349488 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0348171 |
| RRBP1 | ribosome binding protein 1 | -0.0345475 |
| RPL36A | ribosomal protein L36a | -0.032904 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327793 |
| HLA-B | major histocompatibility complex, class I, B | -0.0327519 |
| RPS4X | ribosomal protein S4, X-linked | -0.0327371 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0324482 |
| GNAS | GNAS complex locus | -0.0322375 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0317738 |
| FN1 | fibronectin 1 | -0.0316302 |
| SYAP1 | synapse associated protein 1 | -0.0301701 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0298842 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0288439 |
| RPL37A | ribosomal protein L37a | -0.0278579 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.027592 |
| RPL26 | ribosomal protein L26 | -0.0274831 |
| AHNAK | AHNAK nucleoprotein | -0.0269728 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0268816 |
| RBM39 | RNA binding motif protein 39 | -0.0267925 |
| FLNA | filamin A, alpha | -0.0264799 |
| RPS21 | ribosomal protein S21 | -0.0263398 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0258689 |
| NEK7 | NIMA-related kinase 7 | -0.0256981 |
| GLIS3 | GLIS family zinc finger 3 | -0.0253306 |
| TUBB | tubulin, beta class I | -0.0248066 |
| TMEM123 | transmembrane protein 123 | -0.024792 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0241961 |
| COL1A1 | collagen, type I, alpha 1 | -0.0238819 |
| RPS27A | ribosomal protein S27a | -0.0236758 |
| RPL7 | ribosomal protein L7 | -0.0234605 |
| UBB | ubiquitin B | -0.023393 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0231886 |
| RPLP1 | ribosomal protein, large, P1 | -0.023033 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0228617 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0226653 |
| RPL38 | ribosomal protein L38 | -0.0226532 |
| PERP | PERP, TP53 apoptosis effector | -0.022635 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.022566 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0224795 |
| KLHL5 | kelch-like family member 5 | -0.0223209 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0222273 |
| DEK | DEK proto-oncogene | -0.0221871 |
| RPL13A | ribosomal protein L13a | -0.0220655 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0218173 |
| RPS25 | ribosomal protein S25 | -0.0215794 |
| CCNL1 | cyclin L1 | -0.021517 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0214411 |
| CALR | calreticulin | -0.0213608 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0210252 |
| YBX3 | Y box binding protein 3 | -0.0209495 |
| QKI | QKI, KH domain containing, RNA binding | -0.0209294 |
| RPL11 | ribosomal protein L11 | -0.0208342 |
| RPL35 | ribosomal protein L35 | -0.0207046 |
| TFG | TRK-fused gene | -0.0206205 |
| RPS14 | ribosomal protein S14 | -0.0203778 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0202873 |
| KYNU | kynureninase | -0.0202255 |
| CLIC4 | chloride intracellular channel 4 | -0.01998 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0199146 |
| JAK2 | Janus kinase 2 | -0.0198807 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0198583 |
| HMGB2 | high mobility group box 2 | -0.0198559 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0197736 |
| RPS23 | ribosomal protein S23 | -0.0193576 |
