| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Oxaprozin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Oxaprozin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0380641 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0309799 |
| NDRG1 | N-myc downstream regulated 1 | 0.0259203 |
| NGLY1 | N-glycanase 1 | 0.0226199 |
| FBXO11 | F-box protein 11 | 0.0223481 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0220563 |
| INSIG1 | insulin induced gene 1 | 0.0214812 |
| RPL12 | ribosomal protein L12 | 0.021102 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0195566 |
| FAM13A | family with sequence similarity 13, member A | 0.0195279 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0194862 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0180909 |
| SRP54 | signal recognition particle 54kDa | 0.0177256 |
| SEPTIN2 | septin 2 | 0.017272 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.017051 |
| ADM | adrenomedullin | 0.0170218 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0169298 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0169076 |
| KLF6 | Kruppel-like factor 6 | 0.0169053 |
| NPTN | neuroplastin | 0.0166506 |
| DTNA | dystrobrevin, alpha | 0.0165138 |
| ATF4 | activating transcription factor 4 | 0.0164658 |
| RUFY2 | RUN and FYVE domain containing 2 | 0.0163566 |
| TMEM51 | transmembrane protein 51 | 0.0163378 |
| SELENOF | selenoprotein F | 0.0159044 |
| GPC6 | glypican 6 | 0.0155924 |
| DNM1L | dynamin 1-like | 0.0155762 |
| UBXN4 | UBX domain protein 4 | 0.0154995 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0154738 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0152622 |
| ORC3 | origin recognition complex, subunit 3 | 0.0147695 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.014713 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0146839 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0144988 |
| MTDH | metadherin | 0.0144882 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0142883 |
| RND3 | Rho family GTPase 3 | 0.0142642 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0142594 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.014147 |
| RAI1 | retinoic acid induced 1 | 0.0140587 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0140518 |
| WASHC4 | WASH complex subunit 4 | 0.014018 |
| CEP70 | centrosomal protein 70kDa | 0.0139951 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0139425 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0138489 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0138204 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.013819 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0136423 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0136386 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0136073 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.013498 |
| RPL11 | ribosomal protein L11 | 0.0134793 |
| SMAD2 | SMAD family member 2 | 0.0134577 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.0133196 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0132612 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0132537 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0132512 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0132217 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | 0.0132102 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0131449 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0130555 |
| IPO5 | importin 5 | 0.0130085 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0129912 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0129402 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0128255 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0127521 |
| RPL7 | ribosomal protein L7 | 0.0125393 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0125384 |
| TPP2 | tripeptidyl peptidase II | 0.0124822 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0124787 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0124286 |
| CDK13 | cyclin-dependent kinase 13 | 0.0124021 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0123577 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0123123 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0122871 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0122368 |
| TOB2 | transducer of ERBB2, 2 | 0.0121328 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0121296 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0121197 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.012079 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0119896 |
| USP1 | ubiquitin specific peptidase 1 | 0.011958 |
| SLC35E3 | solute carrier family 35, member E3 | 0.0119317 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.0118466 |
| PROS1 | protein S (alpha) | 0.011815 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0117916 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0117904 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.011703 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0116219 |
| RSBN1 | round spermatid basic protein 1 | 0.011591 |
| BCAP29 | B-cell receptor-associated protein 29 | 0.0115681 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.0115211 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0115142 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0114669 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0113152 |
| ACTG1 | actin gamma 1 | 0.0113109 |
| AK2 | adenylate kinase 2 | 0.0112969 |
| CBFB | core-binding factor, beta subunit | 0.0112666 |
| MYNN | myoneurin | 0.0112522 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0112478 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.204231 |
| CD44 | CD44 molecule (Indian blood group) | -0.0653619 |
| PKM | pyruvate kinase, muscle | -0.0588242 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0513883 |
| UBC | ubiquitin C | -0.0511678 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0497297 |
| ENO1 | enolase 1, (alpha) | -0.0481697 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0418736 |
| RBM39 | RNA binding motif protein 39 | -0.0397524 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0395413 |
| AHNAK | AHNAK nucleoprotein | -0.0394176 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0381041 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0373618 |
| TMSB10 | thymosin beta 10 | -0.0369176 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0364339 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0355021 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0352355 |
| DST | dystonin | -0.035053 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0345438 |
| CALU | calumenin | -0.0343014 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333713 |
| RPS27A | ribosomal protein S27a | -0.0326714 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0322668 |
| SMAD3 | SMAD family member 3 | -0.0321123 |
| MCL1 | myeloid cell leukemia 1 | -0.0319401 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0313959 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0311638 |
| OSMR | oncostatin M receptor | -0.0307389 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0304343 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0304318 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0288346 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0287226 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285949 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0285622 |
| PTMA | prothymosin, alpha | -0.0282467 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.027839 |
| YBX3 | Y box binding protein 3 | -0.0276171 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0275937 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0275389 |
| FUS | FUS RNA binding protein | -0.0272927 |
| USP22 | ubiquitin specific peptidase 22 | -0.0270816 |
| CREBRF | CREB3 regulatory factor | -0.0268477 |
| IPO7 | importin 7 | -0.026837 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0268337 |
| CALR | calreticulin | -0.0268191 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0262311 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0260517 |
| RPL27A | ribosomal protein L27a | -0.0256835 |
| TOP1 | topoisomerase (DNA) I | -0.0254654 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0253903 |
| ERBIN | erbb2 interacting protein | -0.0251695 |
| ATXN1 | ataxin 1 | -0.0250761 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250455 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0248843 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248013 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0245118 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0244002 |
| POTEF | POTE ankyrin domain family, member F | -0.0242939 |
| GOLGB1 | golgin B1 | -0.0241923 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0238961 |
| DEK | DEK proto-oncogene | -0.0238887 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0237574 |
| RPS13 | ribosomal protein S13 | -0.023707 |
| TPX2 | TPX2, microtubule-associated | -0.0235243 |
| ZNF292 | zinc finger protein 292 | -0.0234616 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.0232655 |
| ATG7 | autophagy related 7 | -0.0232141 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0232126 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0229476 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0229429 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0227277 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0223574 |
| RPL23 | ribosomal protein L23 | -0.022271 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0221528 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0221106 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0221087 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0221076 |
| MED13L | mediator complex subunit 13-like | -0.0220335 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0219577 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0217343 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0213912 |
| PRELID2 | PRELI domain containing 2 | -0.0213051 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0212792 |
| CENPF | centromere protein F, 350/400kDa | -0.0211903 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.021167 |
| VMP1 | vacuole membrane protein 1 | -0.0211473 |
| TAOK3 | TAO kinase 3 | -0.0209926 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0209381 |
| VIM | vimentin | -0.0209343 |
| RIOK3 | RIO kinase 3 | -0.0208931 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0207048 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0206513 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0206365 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0205936 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0205769 |
| EFNA5 | ephrin-A5 | -0.0203971 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0202231 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0201399 |
| ANKRD11 | ankyrin repeat domain 11 | -0.02013 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0201119 |
