P-22077 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

14 genes differentially expressed following the P-22077 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WASHC4 WASH complex subunit 4 4.3599
SPRED2 sprouty-related, EVH1 domain containing 2 3.34896
COPZ2 coatomer protein complex, subunit zeta 2 3.26008
ZNF460 zinc finger protein 460 3.23957
TNN tenascin N 3.09874
MFAP5 microfibrillar associated protein 5 3.09283
ISLR immunoglobulin superfamily containing leucine-rich repeat 3.05351

decreased expression

Symbol Name Standardized Value
CD40 CD40 molecule, TNF receptor superfamily member 5 -4.18226
RXYLT1 ribitol xylosyltransferase 1 -3.73764
MAMLD1 mastermind-like domain containing 1 -3.48849
PTPRT protein tyrosine phosphatase, receptor type, T -3.32676
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -3.2612
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.25127
SIK1 salt-inducible kinase 1 -3.17767