| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | prolyl 3-hydroxylase 1|This gene encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 64175) |
| External Link | https://ncbi.nlm.nih.gov/gene/64175 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the P3H1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KYNU | kynureninase | 0.0180774 |
| KRT15 | keratin 15, type I | 0.0136118 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0130832 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0123129 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0119406 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.011514 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0113633 |
| S100A8 | S100 calcium binding protein A8 | 0.0111851 |
| MT1X | metallothionein 1X | 0.0110323 |
| S100A9 | S100 calcium binding protein A9 | 0.0109708 |
| MAGEA3 | melanoma antigen family A3 | 0.0108603 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.0104371 |
| MGP | matrix Gla protein | 0.010413 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.0103294 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0102888 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0102488 |
| PDGFC | platelet derived growth factor C | 0.0101132 |
| PRR7 | proline rich 7 (synaptic) | 0.0100371 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00997137 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00995287 |
| GOLT1B | golgi transport 1B | 0.00975811 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00966552 |
| MT1H | metallothionein 1H | 0.00966218 |
| MT1G | metallothionein 1G | 0.00959201 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00958723 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00954404 |
| ALB | albumin | 0.0094332 |
| TMEM45A | transmembrane protein 45A | 0.00936342 |
| PERP | PERP, TP53 apoptosis effector | 0.00923781 |
| KRT5 | keratin 5, type II | 0.00920894 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0090809 |
| ITGA6 | integrin, alpha 6 | 0.00901891 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0090121 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00897522 |
| MT1F | metallothionein 1F | 0.00895802 |
| XIC | X chromosome inactivation center | 0.00895526 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00892581 |
| SPRR2B | small proline-rich protein 2B | 0.00877771 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00876281 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0086522 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00864052 |
| S100P | S100 calcium binding protein P | 0.0086037 |
| KRT6B | keratin 6B, type II | 0.00859344 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00851984 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00848945 |
| CCNA2 | cyclin A2 | 0.00843894 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00841331 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00835634 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00822249 |
| S100A12 | S100 calcium binding protein A12 | 0.00801512 |
| TPBG | trophoblast glycoprotein | 0.00799932 |
| MCL1 | myeloid cell leukemia 1 | 0.00797121 |
| KIF2C | kinesin family member 2C | 0.00787392 |
| FGG | fibrinogen gamma chain | 0.00784343 |
| SPP1 | secreted phosphoprotein 1 | 0.0077753 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0076528 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.0076463 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00764035 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00751577 |
| DEFB4A | defensin, beta 4A | 0.00747134 |
| MAGEA12 | melanoma antigen family A12 | 0.00739718 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00738262 |
| MFSD1 | major facilitator superfamily domain containing 1 | 0.0073702 |
| C4BPA | complement component 4 binding protein, alpha | 0.007367 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00736198 |
| FGA | fibrinogen alpha chain | 0.00735408 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00735269 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.0073514 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00734833 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.00733638 |
| RHOB | ras homolog family member B | 0.00730233 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00729318 |
| MGLL | monoglyceride lipase | 0.00726651 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00722584 |
| CTSA | cathepsin A | 0.00721221 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00720534 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00717768 |
| KRT23 | keratin 23, type I | 0.0071725 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00711043 |
| MT1E | metallothionein 1E | 0.00710079 |
| ABLIM1 | actin binding LIM protein 1 | 0.00709928 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00706726 |
| KRT6A | keratin 6A, type II | 0.00705325 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00705264 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00699186 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0069765 |
| SPRR3 | small proline-rich protein 3 | 0.00685121 |
| TESC | tescalcin | 0.00683063 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.00680909 |
| IRS1 | insulin receptor substrate 1 | 0.00680671 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00672993 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00671952 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 0.00669733 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00668784 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00668523 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.00667383 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00664143 |
| IL6ST | interleukin 6 signal transducer | 0.00660669 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00659574 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00658683 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00658317 |
| ZNF589 | zinc finger protein 589 | 0.00657579 |
| CFD | complement factor D (adipsin) | 0.00655433 |
| PAX5 | paired box 5 | 0.00650682 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00648237 |
| YME1L1 | YME1-like 1 ATPase | 0.00648126 |
| PCDH9 | protocadherin 9 | 0.00647735 |
| MT2A | metallothionein 2A | 0.00646445 |
| LY96 | lymphocyte antigen 96 | 0.00644902 |
| TPRKB | TP53RK binding protein | 0.00644661 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.00643271 |
| TMEM106B | transmembrane protein 106B | 0.00641082 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00638994 |
| NOTCH2 | notch 2 | 0.00638115 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00638029 |
| RNFT1 | ring finger protein, transmembrane 1 | 0.00636024 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00635495 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.0062794 |
| CD163 | CD163 molecule | 0.00627856 |
| MOB4 | MOB family member 4, phocein | 0.00617775 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00617668 |
| CAV2 | caveolin 2 | 0.00614006 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00613339 |
| CD72 | CD72 molecule | 0.00612272 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.00611754 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00611334 |
| AREG | amphiregulin | 0.00610095 |
| IL7R | interleukin 7 receptor | 0.00609801 |
| VTN | vitronectin | 0.00609311 |
| TSPYL2 | TSPY-like 2 | 0.00608599 |
| ADI1 | acireductone dioxygenase 1 | 0.00608271 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00607266 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00606931 |
| TRH | thyrotropin-releasing hormone | 0.00604905 |
| INHBB | inhibin, beta B | 0.00603691 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00603053 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00602945 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00600072 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00599857 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00598554 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00596559 |
| CD52 | CD52 molecule | 0.00595049 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00594773 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00594567 |
| GLRX | glutaredoxin (thioltransferase) | 0.00593975 |
| CANX | calnexin | 0.00589947 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0058893 |
| EGR1 | early growth response 1 | 0.00588809 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00586297 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.00585388 |
| DUSP1 | dual specificity phosphatase 1 | 0.00583485 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.00582909 |
| RND3 | Rho family GTPase 3 | 0.00581274 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00579068 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00578529 |
| ASPH | aspartate beta-hydroxylase | 0.00577464 |
| ANKRD12 | ankyrin repeat domain 12 | 0.00576285 |
| S100A7 | S100 calcium binding protein A7 | 0.00575223 |
| CAMP | cathelicidin antimicrobial peptide | 0.00575023 |
| RHCG | Rh family, C glycoprotein | 0.00574572 |
| PIGG | phosphatidylinositol glycan anchor biosynthesis, class G | 0.00572799 |
| EPCAM | epithelial cell adhesion molecule | 0.00572689 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00572569 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00572058 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00572002 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00571649 |
| TRIM44 | tripartite motif containing 44 | 0.00569848 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00568708 |
| MMP7 | matrix metallopeptidase 7 | 0.00568678 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00567924 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00565448 |
| MT1M | metallothionein 1M | 0.00563399 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00562896 |
| CLDN1 | claudin 1 | 0.00561774 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.00559443 |
| HHEX | hematopoietically expressed homeobox | 0.00558408 |
| SPRR1A | small proline-rich protein 1A | 0.00558396 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00553692 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.00551054 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00550925 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00549273 |
| BAG3 | BCL2-associated athanogene 3 | 0.00545005 |
| MYO1B | myosin IB | 0.00543988 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00542983 |
| ESR1 | estrogen receptor 1 | 0.00542771 |
| MPZL2 | myelin protein zero-like 2 | 0.00542323 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00541344 |
| ZMPSTE24 | zinc metallopeptidase STE24 | 0.00540466 |
| RRAGD | Ras-related GTP binding D | 0.00540075 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.00539574 |
| ANGPTL4 | angiopoietin-like 4 | 0.00538822 |
| EMP1 | epithelial membrane protein 1 | 0.0053857 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00538416 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.00538209 |
| HIST1H2AC | histone cluster 1, H2ac | 0.005376 |
| FGB | fibrinogen beta chain | 0.00536165 |
| TSPAN13 | tetraspanin 13 | 0.00535891 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.00535751 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00535067 |
| ZFP36 | ZFP36 ring finger protein | 0.00534106 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00533846 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00532123 |
| DBN1 | drebrin 1 | 0.00530277 |
| ARMT1 | acidic residue methyltransferase 1 | 0.00530163 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | 0.0052951 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0052881 |
| YAP1 | Yes-associated protein 1 | 0.00528689 |
| TSPO | translocator protein (18kDa) | 0.00528673 |
| VEGFA | vascular endothelial growth factor A | 0.00528385 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00528057 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00528025 |
| RGS16 | regulator of G-protein signaling 16 | 0.00528007 |
| KMT5B | lysine methyltransferase 5B | 0.00524043 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00523363 |
| RTN4 | reticulon 4 | 0.00522342 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00521914 |
| ERGIC2 | ERGIC and golgi 2 | 0.00520928 |
| DUSP3 | dual specificity phosphatase 3 | 0.00520363 |
| CD96 | CD96 molecule | 0.00520319 |
| CD38 | CD38 molecule | 0.00519944 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.00519902 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00518598 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | 0.00516119 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00514373 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00513323 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.0051332 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00512935 |
| GRB14 | growth factor receptor-bound protein 14 | 0.0051245 |
| SPRR1B | small proline-rich protein 1B | 0.00511504 |
| CNPY2 | canopy FGF signaling regulator 2 | 0.00510775 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 | 0.00509674 |
| GOLGA4 | golgin A4 | 0.00509048 |
| BCL2A1 | BCL2-related protein A1 | 0.00508858 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.00508831 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00508778 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00508079 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0050424 |
| MRTFB | myocardin related transcription factor B | 0.00503456 |
| LYZ | lysozyme | 0.005026 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00502469 |
| CREM | cAMP responsive element modulator | 0.00498715 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00498706 |
| GPX2 | glutathione peroxidase 2 | 0.00498576 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00497747 |
| POR | P450 (cytochrome) oxidoreductase | 0.00496976 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.0049584 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.00493686 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00493538 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFITM1 | interferon induced transmembrane protein 1 | -0.0122977 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0112822 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0112595 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0105837 |
| ASS1 | argininosuccinate synthase 1 | -0.0102289 |
| MEN1 | multiple endocrine neoplasia I | -0.0100697 |
| FNBP1 | formin binding protein 1 | -0.0100453 |
| STMN2 | stathmin 2 | -0.00991085 |
| NPTX2 | neuronal pentraxin II | -0.0096045 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00942039 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00939159 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00938091 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00929996 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00915793 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -0.00881504 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00879736 |
| ADD3 | adducin 3 (gamma) | -0.00857059 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00844332 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00839201 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00836552 |
| GNAS | GNAS complex locus | -0.00814151 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.00813606 |
| XPO7 | exportin 7 | -0.0081225 |
| CCND2 | cyclin D2 | -0.00794234 |
| TMEM176B | transmembrane protein 176B | -0.00784328 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00776062 |
| CD99 | CD99 molecule | -0.00769582 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00768163 |
| DAPK1 | death-associated protein kinase 1 | -0.0076282 |
| ATXN1 | ataxin 1 | -0.00758264 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00751197 |
| NSG1 | neuron specific gene family member 1 | -0.00749752 |
| NPY | neuropeptide Y | -0.0074943 |
| ABHD4 | abhydrolase domain containing 4 | -0.00749083 |
| CDC42 | cell division cycle 42 | -0.00745325 |
| GAS1 | growth arrest-specific 1 | -0.00744733 |
| ADA | adenosine deaminase | -0.00743796 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.00741153 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00738464 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -0.00737666 |
| L1CAM | L1 cell adhesion molecule | -0.0073422 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.007316 |
| FGL2 | fibrinogen-like 2 | -0.00730367 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | -0.00729849 |
| SST | somatostatin | -0.00729477 |
| REEP1 | receptor accessory protein 1 | -0.00723738 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00721566 |
| NEFH | neurofilament, heavy polypeptide | -0.00720271 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00719735 |
| CCNB1 | cyclin B1 | -0.00717648 |
| RTN1 | reticulon 1 | -0.00717423 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00715332 |
| TPM2 | tropomyosin 2 (beta) | -0.00713458 |
| CALHM2 | calcium homeostasis modulator 2 | -0.00712023 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00711799 |
| PNMA8A | PNMA family member 8A | -0.00709827 |
| CHKB | choline kinase beta | -0.00709651 |
| GLO1 | glyoxalase I | -0.00709259 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00706097 |
| FASN | fatty acid synthase | -0.00689964 |
| STON1 | stonin 1 | -0.00687527 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00684876 |
| RTN2 | reticulon 2 | -0.00681892 |
| DACH1 | dachshund family transcription factor 1 | -0.00680102 |
| TRIM36 | tripartite motif containing 36 | -0.00676776 |
| OLFML2A | olfactomedin-like 2A | -0.006766 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00676118 |
| GSDME | gasdermin E | -0.00673471 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.0067281 |
| ENOPH1 | enolase-phosphatase 1 | -0.00672464 |
| VWA5A | von Willebrand factor A domain containing 5A | -0.0066859 |
| SLC17A6 | solute carrier family 17 (vesicular glutamate transporter), member 6 | -0.00667747 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00664511 |
| CLIC5 | chloride intracellular channel 5 | -0.00662205 |
| EMX2 | empty spiracles homeobox 2 | -0.00661945 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00657595 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00655113 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 | -0.00655047 |
| GPR183 | G protein-coupled receptor 183 | -0.00654454 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00651097 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00650599 |
| TSPAN15 | tetraspanin 15 | -0.00648936 |
| GPX1 | glutathione peroxidase 1 | -0.00645377 |
| CHN2 | chimerin 2 | -0.00644535 |
| KAZN | kazrin, periplakin interacting protein | -0.00644327 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0064107 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | -0.00639416 |
| C8ORF33 | chromosome 8 open reading frame 33 | -0.00638832 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00638169 |
| GAL | galanin/GMAP prepropeptide | -0.00636121 |
| OLFML3 | olfactomedin-like 3 | -0.00634984 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00631737 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00627728 |
| H2AX | H2A.X variant histone | -0.00626281 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00621649 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00621399 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00620284 |
| KIF1A | kinesin family member 1A | -0.00618555 |
| CDK19 | cyclin-dependent kinase 19 | -0.00616228 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00614689 |
| BEX4 | brain expressed, X-linked 4 | -0.0061416 |
| PRUNE1 | prune exopolyphosphatase 1 | -0.00612838 |
| PENK | proenkephalin | -0.00612684 |
| CHEK2 | checkpoint kinase 2 | -0.00611054 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00610092 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00608711 |
| MLF1 | myeloid leukemia factor 1 | -0.00607987 |
| FAR2 | fatty acyl CoA reductase 2 | -0.0060781 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00607269 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00605834 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00600402 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00598998 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00594919 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.00594841 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -0.00592973 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00590443 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0058785 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00584249 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00583444 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00582753 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00582189 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00582055 |
| NLGN4X | neuroligin 4, X-linked | -0.00580944 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0057881 |
| PTHLH | parathyroid hormone-like hormone | -0.00577171 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00574642 |
| RCAN2 | regulator of calcineurin 2 | -0.00573973 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0057362 |
| NID2 | nidogen 2 (osteonidogen) | -0.00572691 |
| OLFM1 | olfactomedin 1 | -0.00572459 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00571935 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.00569629 |
| CALCA | calcitonin-related polypeptide alpha | -0.00569256 |
| TAGLN3 | transgelin 3 | -0.00568511 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00565259 |
| CDC42SE1 | CDC42 small effector 1 | -0.00564815 |
| EIF4E | eukaryotic translation initiation factor 4E | -0.00558468 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00558411 |
| AHR | aryl hydrocarbon receptor | -0.005568 |
| LEFTY1 | left-right determination factor 1 | -0.00555603 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00555167 |
| DOK5 | docking protein 5 | -0.00554606 |
| PCNA | proliferating cell nuclear antigen | -0.00553866 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00553521 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00553457 |
| KLK6 | kallikrein-related peptidase 6 | -0.00552255 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00552151 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00550099 |
| RNF144A | ring finger protein 144A | -0.00549837 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | -0.00548597 |
| TBC1D12 | TBC1 domain family, member 12 | -0.00546725 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00546634 |
| NAGA | N-acetylgalactosaminidase, alpha- | -0.00546067 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00545509 |
| RRAS | related RAS viral (r-ras) oncogene homolog | -0.00545113 |
| PEG3 | paternally expressed 3 | -0.00544541 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00541384 |
| AHCY | adenosylhomocysteinase | -0.00540809 |
| GATA2 | GATA binding protein 2 | -0.00539471 |
| TPM4 | tropomyosin 4 | -0.0053922 |
| FNTA | farnesyltransferase, CAAX box, alpha | -0.00538484 |
| TSPAN8 | tetraspanin 8 | -0.00538268 |
| SASH3 | SAM and SH3 domain containing 3 | -0.00535489 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00534956 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.00534181 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | -0.00533208 |
| TRIM8 | tripartite motif containing 8 | -0.00531826 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00531689 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit | -0.00530898 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00530716 |
| PRMT1 | protein arginine methyltransferase 1 | -0.00530642 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00529793 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00529633 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | -0.0052925 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0052909 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00525857 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00525093 |
| LSAMP | limbic system-associated membrane protein | -0.0052411 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00522728 |
| KIAA0125 | KIAA0125 | -0.00522479 |
| MEIS1 | Meis homeobox 1 | -0.00522356 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00521807 |
| RUNX3 | runt-related transcription factor 3 | -0.0051808 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00517044 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00516753 |
| GAP43 | growth associated protein 43 | -0.00516413 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0051562 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | -0.00514797 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00514444 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00514218 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00510974 |
| GPX3 | glutathione peroxidase 3 | -0.00510857 |
| LAPTM5 | lysosomal protein transmembrane 5 | -0.00510578 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00510409 |
| KLK8 | kallikrein-related peptidase 8 | -0.00510194 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.00509809 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -0.00507611 |
| F8 | coagulation factor VIII, procoagulant component | -0.00507167 |
| LRRC49 | leucine rich repeat containing 49 | -0.00506861 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00506336 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00505282 |
| SMYD3 | SET and MYND domain containing 3 | -0.0050506 |
| TUSC3 | tumor suppressor candidate 3 | -0.00504184 |
| LIMK2 | LIM domain kinase 2 | -0.00503862 |
| PRKCA | protein kinase C, alpha | -0.00502555 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | -0.00502416 |
| TMEM176A | transmembrane protein 176A | -0.00501809 |
| NEFM | neurofilament, medium polypeptide | -0.00501685 |
| TADA2A | transcriptional adaptor 2A | -0.00499299 |
| RLN2 | relaxin 2 | -0.00498555 |
| KLK11 | kallikrein-related peptidase 11 | -0.00498362 |
| PLEK | pleckstrin | -0.00497909 |
| PNKP | polynucleotide kinase 3'-phosphatase | -0.00497816 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00497794 |
| PLAT | plasminogen activator, tissue | -0.00497698 |
| PINLYP | phospholipase A2 inhibitor and LY6/PLAUR domain containing | -0.00497015 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.00496696 |
| DSE | dermatan sulfate epimerase | -0.00496383 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0049549 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.0049529 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -0.0049408 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00490058 |
| CNOT9 | CCR4-NOT transcription complex subunit 9 | -0.00490023 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00488899 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.00488751 |
| ARG2 | arginase 2 | -0.00488068 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00487859 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00487485 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -0.00487131 |
| FTO | fat mass and obesity associated | -0.00485208 |
| MAP1A | microtubule-associated protein 1A | -0.00484142 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00483959 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | -0.00482926 |
| ACACA | acetyl-CoA carboxylase alpha | -0.00481675 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00479149 |
| LEPR | leptin receptor | -0.00478933 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.00476953 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | -0.00476694 |
| CCDC92 | coiled-coil domain containing 92 | -0.00475767 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00475513 |
| TLR4 | toll-like receptor 4 | -0.00474473 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0047327 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.0047196 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | -0.00471956 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00471924 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00471791 |
| TMEM100 | transmembrane protein 100 | -0.00471582 |
| TAC1 | tachykinin, precursor 1 | -0.00471332 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00469613 |
| SELPLG | selectin P ligand | -0.00469157 |
