P3H3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description prolyl 3-hydroxylase 3|The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 10536)
External Link https://ncbi.nlm.nih.gov/gene/10536
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Genes

497 genes differentially expressed following the P3H3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0175028
LCN2 lipocalin 2 0.0160829
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.015149
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0138139
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0137979
LGALS13 lectin, galactoside-binding, soluble, 13 0.0135483
DEFB1 defensin, beta 1 0.013384
KRT14 keratin 14, type I 0.013174
CCL20 chemokine (C-C motif) ligand 20 0.0127145
CXCL8 chemokine (C-X-C motif) ligand 8 0.0121239
KRT15 keratin 15, type I 0.0120901
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0114311
TFF1 trefoil factor 1 0.0114063
REG1A regenerating islet-derived 1 alpha 0.0112572
OLFM4 olfactomedin 4 0.0112376
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0109521
GNAS GNAS complex locus 0.0107681
KRT19 keratin 19, type I 0.0104658
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.0103622
CRABP2 cellular retinoic acid binding protein 2 0.0103582
MAGEA3 melanoma antigen family A3 0.0102108
PRAME preferentially expressed antigen in melanoma 0.0101633
XIC X chromosome inactivation center 0.0100986
ABHD6 abhydrolase domain containing 6 0.0100299
TSPAN8 tetraspanin 8 0.0098786
IFI44 interferon-induced protein 44 0.00981162
RCAN1 regulator of calcineurin 1 0.00979829
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00979608
ASS1 argininosuccinate synthase 1 0.00978374
IFI27 interferon, alpha-inducible protein 27 0.00963512
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00941898
PEG3 paternally expressed 3 0.00936729
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00922706
PI3 peptidase inhibitor 3, skin-derived 0.00905566
CES1 carboxylesterase 1 0.00890419
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00887718
FCGBP Fc fragment of IgG binding protein 0.00878268
CFB complement factor B 0.00866981
CXCL14 chemokine (C-X-C motif) ligand 14 0.00865523
PENK proenkephalin 0.00863504
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00862818
IFI6 interferon, alpha-inducible protein 6 0.00858549
PITX3 paired-like homeodomain 3 0.00857731
NPTX2 neuronal pentraxin II 0.00846964
TM4SF1 transmembrane 4 L six family member 1 0.00843214
MX1 MX dynamin-like GTPase 1 0.00841828
S100A7 S100 calcium binding protein A7 0.00831962
MX2 MX dynamin-like GTPase 2 0.00820573
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00794627
LGALS4 lectin, galactoside-binding, soluble, 4 0.00793035
IFI16 interferon, gamma-inducible protein 16 0.00790216
ADD3 adducin 3 (gamma) 0.00789873
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00786761
MDK midkine (neurite growth-promoting factor 2) 0.00782804
IFITM1 interferon induced transmembrane protein 1 0.0076818
MAGEA12 melanoma antigen family A12 0.00766792
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00764921
MXRA5 matrix-remodelling associated 5 0.00762539
PDZK1IP1 PDZK1 interacting protein 1 0.00758474
HIST1H2AC histone cluster 1, H2ac 0.00758451
NELL2 NEL-like 2 (chicken) 0.00756791
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00754371
HOXC6 homeobox C6 0.00754167
IFITM3 interferon induced transmembrane protein 3 0.00749713
STK10 serine/threonine kinase 10 0.00746908
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa 0.00745292
CSTA cystatin A (stefin A) 0.00744608
S100A12 S100 calcium binding protein A12 0.00742309
LTF lactotransferrin 0.00738834
VCAN versican 0.00737298
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00727014
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00719757
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00717166
KRT17 keratin 17, type I 0.00709951
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00705759
KLK11 kallikrein-related peptidase 11 0.00705065
ISG15 ISG15 ubiquitin-like modifier 0.00700622
AQP9 aquaporin 9 0.00699089
MSX1 msh homeobox 1 0.00692885
TMPRSS4 transmembrane protease, serine 4 0.00691259
IGFBP1 insulin-like growth factor binding protein 1 0.0068937
CHP1 calcineurin-like EF-hand protein 1 0.00688122
PROM1 prominin 1 0.00686612
SCGB2A2 secretoglobin, family 2A, member 2 0.00680132
AEBP1 AE binding protein 1 0.00678581
IL1RN interleukin 1 receptor antagonist 0.00677376
HOXB7 homeobox B7 0.00674684
NSG1 neuron specific gene family member 1 0.0067057
PTGES prostaglandin E synthase 0.00669006
MIA melanoma inhibitory activity 0.00667546
ADI1 acireductone dioxygenase 1 0.00662371
IFITM2 interferon induced transmembrane protein 2 0.00655905
S100A11 S100 calcium binding protein A11 0.00649617
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00647205
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00646978
KRT5 keratin 5, type II 0.00645054
FAM171A1 family with sequence similarity 171, member A1 0.00642529
CYTL1 cytokine-like 1 0.0063637
PNMA8A PNMA family member 8A 0.00634997
KLK10 kallikrein-related peptidase 10 0.00634878
MICB MHC class I polypeptide-related sequence B 0.00633649
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00627773
MEN1 multiple endocrine neoplasia I 0.00624058
MUC4 mucin 4, cell surface associated 0.0062184
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00618337
NUTF2 nuclear transport factor 2 0.00617277
CTSK cathepsin K 0.00616078
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00611743
C5AR1 complement component 5a receptor 1 0.00611585
PLAT plasminogen activator, tissue 0.00609048
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00608294
ANPEP alanyl (membrane) aminopeptidase 0.0060776
HOXC10 homeobox C10 0.0060665
H1-2 H1.2 linker histone, cluster member 0.00605663
IFI44L interferon-induced protein 44-like 0.00603192
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00601243
HMGA1 high mobility group AT-hook 1 0.00600941
SAMD9 sterile alpha motif domain containing 9 0.00599688
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00597661
SRPX sushi-repeat containing protein, X-linked 0.00597378
RETREG1 reticulophagy regulator 1 0.00596191
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0059545
LEF1 lymphoid enhancer-binding factor 1 0.00591423
SFRP1 secreted frizzled-related protein 1 0.00588862
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00584604
SH2B3 SH2B adaptor protein 3 0.00584599
BEX1 brain expressed, X-linked 1 0.00578121
CRYAB crystallin, alpha B 0.00576557
COMP cartilage oligomeric matrix protein 0.00575869
DAXX death-domain associated protein 0.0057524
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00574485
GREM1 gremlin 1, DAN family BMP antagonist 0.00574138
LOX lysyl oxidase 0.00572777
CALR calreticulin 0.00572703
MT1X metallothionein 1X 0.00570552
HOXB2 homeobox B2 0.00570322
COL14A1 collagen, type XIV, alpha 1 0.00570013
OASL 2'-5'-oligoadenylate synthetase-like 0.0056892
HIST1H2BK histone cluster 1, H2bk 0.00567393
FRZB frizzled-related protein 0.0056622
IL1B interleukin 1, beta 0.00565854
CXCL3 chemokine (C-X-C motif) ligand 3 0.00565664
LPAR6 lysophosphatidic acid receptor 6 0.00565
MCAM melanoma cell adhesion molecule 0.00563753
BAMBI BMP and activin membrane-bound inhibitor 0.00563496
GAS7 growth arrest-specific 7 0.00558478
PBLD phenazine biosynthesis-like protein domain containing 0.0055833
HOXB6 homeobox B6 0.00557683
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00557477
ITM2C integral membrane protein 2C 0.0055721
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00557102
NT5E 5'-nucleotidase, ecto (CD73) 0.00552815
TMEM45A transmembrane protein 45A 0.0054926
CLEC11A C-type lectin domain family 11, member A 0.00548663
RRAD Ras-related associated with diabetes 0.00548125
S100B S100 calcium binding protein B 0.00547437
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00546273
ISG20 interferon stimulated exonuclease gene 20kDa 0.0054588
CTSG cathepsin G 0.00544198
VIM vimentin 0.00543381
GPM6B glycoprotein M6B 0.00542152
AMDHD2 amidohydrolase domain containing 2 0.00542091
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00541272
IVNS1ABP influenza virus NS1A binding protein 0.0054089
IL24 interleukin 24 0.00540887
LINC00623 long intergenic non-protein coding RNA 623 0.00540625
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.0053981
SORD sorbitol dehydrogenase 0.0053767
WDR26 WD repeat domain 26 0.00537289
OLFML3 olfactomedin-like 3 0.00536469
REG3A regenerating islet-derived 3 alpha 0.00534171
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00533647
THBS4 thrombospondin 4 0.00533516
PDLIM4 PDZ and LIM domain 4 0.00533101
ANXA6 annexin A6 0.00531611
DLK1 delta-like 1 homolog (Drosophila) 0.00530398
LSP1 lymphocyte-specific protein 1 0.00530026
TFPI2 tissue factor pathway inhibitor 2 0.00529108
TUBB2B tubulin, beta 2B class IIb 0.00528033
NDN necdin, melanoma antigen (MAGE) family member 0.00527015
PRKCA protein kinase C, alpha 0.00525798
APOB apolipoprotein B 0.00525641
CCNG1 cyclin G1 0.00524891
G0S2 G0/G1 switch 2 0.0052439
PGF placental growth factor 0.0052014
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00518406
AOX1 aldehyde oxidase 1 0.00518294
CFI complement factor I 0.00517034
CFD complement factor D (adipsin) 0.0051578
EMP1 epithelial membrane protein 1 0.00514924
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.00514602
NVL nuclear VCP-like 0.00510749
DNMBP dynamin binding protein 0.00510322
RHCG Rh family, C glycoprotein 0.00508102
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00507706
ARG2 arginase 2 0.00507458
AKAP12 A kinase (PRKA) anchor protein 12 0.00507152
CDCP1 CUB domain containing protein 1 0.00507054
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00506877
MT2A metallothionein 2A 0.00504471
FABP1 fatty acid binding protein 1, liver 0.00503845
HNRNPL heterogeneous nuclear ribonucleoprotein L 0.00503788
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00503754
REG1B regenerating islet-derived 1 beta 0.00502845
MMD monocyte to macrophage differentiation-associated 0.00502542
TUBB2A tubulin, beta 2A class IIa 0.00502233
HOXC4 homeobox C4 0.00501846
CD99 CD99 molecule 0.00500423
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00498262
FOSL2 FOS-like antigen 2 0.0049745
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00496714
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00495256
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.0049489
AZU1 azurocidin 1 0.0049404
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00493251
EGFL6 EGF-like-domain, multiple 6 0.00492426
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0049217
KRT13 keratin 13, type I 0.00491892
XBP1 X-box binding protein 1 0.00491709
TP53I3 tumor protein p53 inducible protein 3 0.00491341
TGFA transforming growth factor, alpha 0.00491306
QPRT quinolinate phosphoribosyltransferase 0.00489666
HSPA2 heat shock 70kDa protein 2 0.00488075
JUND jun D proto-oncogene 0.00487137
VNN1 vanin 1 0.00485889
PRDX2 peroxiredoxin 2 0.00485806
FMOD fibromodulin 0.00485428
INHBA inhibin, beta A 0.00485294
KLK8 kallikrein-related peptidase 8 0.00484959
ALB albumin 0.00484915
TSPAN14 tetraspanin 14 0.00484844
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.0048449
CLEC2B C-type lectin domain family 2, member B 0.0048387
GOLGA8H golgin A8 family, member H 0.0048279
PARP8 poly (ADP-ribose) polymerase family, member 8 0.004827
ATF3 activating transcription factor 3 0.00479354
DEGS1 delta(4)-desaturase, sphingolipid 1 0.004786
SRPX2 sushi-repeat containing protein, X-linked 2 0.00477395
PTEN phosphatase and tensin homolog 0.00476305
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.0047618
TRIM29 tripartite motif containing 29 0.00474998
S100A2 S100 calcium binding protein A2 0.00474404
CD96 CD96 molecule 0.00473113
STAB1 stabilin 1 0.00472585
SYNM synemin, intermediate filament protein 0.00471356
GPSM3 G-protein signaling modulator 3 0.0046979
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00469332
DCN decorin 0.00469308
RTN3 reticulon 3 0.00468913

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0124947
HOPX HOP homeobox -0.0124697
MEF2C myocyte enhancer factor 2C -0.0113342
MAP7 microtubule-associated protein 7 -0.0111795
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0110364
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.010947
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0101095
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0100476
SFTPC surfactant protein C -0.0100189
CADM1 cell adhesion molecule 1 -0.00998301
MYBPC1 myosin binding protein C, slow type -0.00968607
TNS3 tensin 3 -0.00965491
PHACTR2 phosphatase and actin regulator 2 -0.00953182
GJA1 gap junction protein, alpha 1, 43kDa -0.00949166
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00932728
CLU clusterin -0.00863191
SFTPA2 surfactant protein A2 -0.0085895
SFTPB surfactant protein B -0.00847265
TBX2 T-box 2 -0.00836547
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00818923
TTN titin -0.00814565
TXNDC9 thioredoxin domain containing 9 -0.00812496
ZNF589 zinc finger protein 589 -0.00804304
NCALD neurocalcin delta -0.00762326
VEGFA vascular endothelial growth factor A -0.00753372
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00748672
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0074275
SFTPD surfactant protein D -0.00742174
HMGB3 high mobility group box 3 -0.00739044
CCNF cyclin F -0.0073854
NPR3 natriuretic peptide receptor 3 -0.00730374
SLC38A1 solute carrier family 38, member 1 -0.00724594
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00723695
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00720235
AKR1C1 aldo-keto reductase family 1, member C1 -0.00709286
TSPAN5 tetraspanin 5 -0.00708104
ALCAM activated leukocyte cell adhesion molecule -0.00705713
PDGFC platelet derived growth factor C -0.00695279
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00693678
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00692942
CA2 carbonic anhydrase II -0.00690881
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00690207
RGS1 regulator of G-protein signaling 1 -0.00690083
PLN phospholamban -0.00686311
CD200 CD200 molecule -0.00671046
CYB5A cytochrome b5 type A (microsomal) -0.00669878
AKR1C3 aldo-keto reductase family 1, member C3 -0.00668654
AKR1C2 aldo-keto reductase family 1, member C2 -0.00664343
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00661517
C4BPA complement component 4 binding protein, alpha -0.00655261
PDE8B phosphodiesterase 8B -0.00654648
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00653081
IDO1 indoleamine 2,3-dioxygenase 1 -0.00649307
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00645818
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.0064546
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00642528
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00637168
MYH11 myosin, heavy chain 11, smooth muscle -0.00635006
TFRC transferrin receptor -0.00633462
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00628778
CBX7 chromobox homolog 7 -0.00624968
FCN3 ficolin (collagen/fibrinogen domain containing) 3 -0.00622936
FRY furry homolog (Drosophila) -0.0061779
TNNC1 troponin C type 1 (slow) -0.00617191
LBH limb bud and heart development -0.00612912
EFNB2 ephrin-B2 -0.00604818
ZBTB38 zinc finger and BTB domain containing 38 -0.00602929
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00601324
PLA2G2D phospholipase A2, group IID -0.00599825
PLPP3 phospholipid phosphatase 3 -0.00594921
FZD5 frizzled class receptor 5 -0.00594738
RHOBTB2 Rho-related BTB domain containing 2 -0.00586696
FHL1 four and a half LIM domains 1 -0.00583116
NDNF neuron-derived neurotrophic factor -0.00581899
DPYSL3 dihydropyrimidinase-like 3 -0.00579788
CTSH cathepsin H -0.0057925
EPHA4 EPH receptor A4 -0.0057825
AQP4 aquaporin 4 -0.00575631
CHIT1 chitinase 1 (chitotriosidase) -0.00574775
TNNT1 troponin T type 1 (skeletal, slow) -0.00571369
C8ORF4 chromosome 8 open reading frame 4 -0.00570372
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00566861
FBP1 fructose-1,6-bisphosphatase 1 -0.00562329
ADAM28 ADAM metallopeptidase domain 28 -0.00561025
NRGN neurogranin (protein kinase C substrate, RC3) -0.00560786
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00556897
EHD2 EH-domain containing 2 -0.00555356
TACC1 transforming, acidic coiled-coil containing protein 1 -0.00554722
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.0055217
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00552122
KDM5D lysine (K)-specific demethylase 5D -0.00549899
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00549038
CUX1 cut-like homeobox 1 -0.00548276
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00546545
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00546495
NEBL nebulette -0.00544111
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00542709
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00541942
CERK ceramide kinase -0.00539871
TOX thymocyte selection-associated high mobility group box -0.00538034
AQP1 aquaporin 1 (Colton blood group) -0.00537378
MCM5 minichromosome maintenance complex component 5 -0.0053701
KLHL41 kelch-like family member 41 -0.00535936
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00534962
SLN sarcolipin -0.0053486
NCKIPSD NCK interacting protein with SH3 domain -0.00532089
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00530394
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00529143
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00523193
CRIP2 cysteine-rich protein 2 -0.00522641
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00522309
ANOS1 anosmin 1 -0.00522301
PTPRM protein tyrosine phosphatase, receptor type, M -0.00520387
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00519856
DMD dystrophin -0.0051893
METAP1 methionyl aminopeptidase 1 -0.0051822
SCGN secretagogin, EF-hand calcium binding protein -0.00517028
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00514188
VIPR1 vasoactive intestinal peptide receptor 1 -0.00514139
DIO2 deiodinase, iodothyronine, type II -0.00514107
GADD45G growth arrest and DNA-damage-inducible, gamma -0.00512841
PARM1 prostate androgen-regulated mucin-like protein 1 -0.00512156
ALPL alkaline phosphatase, liver/bone/kidney -0.00510724
NKX2-1 NK2 homeobox 1 -0.00505558
REEP1 receptor accessory protein 1 -0.00504542
CNTNAP2 contactin associated protein-like 2 -0.00502421
SYT17 synaptotagmin XVII -0.00501882
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.0050172
DOCK9 dedicator of cytokinesis 9 -0.00501346
EIF2D eukaryotic translation initiation factor 2D -0.00501089
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00499552
SETBP1 SET binding protein 1 -0.00497396
TPSAB1 tryptase alpha/beta 1 -0.00493521
ZBTB20 zinc finger and BTB domain containing 20 -0.00491873
RHOBTB3 Rho-related BTB domain containing 3 -0.00491483
NXN nucleoredoxin -0.00490284
ITM2A integral membrane protein 2A -0.00489234
RBPMS RNA binding protein with multiple splicing -0.00487741
ACD adrenocortical dysplasia homolog (mouse) -0.00487006
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00486056
CKM creatine kinase, muscle -0.00485598
MB myoglobin -0.00484033
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00482558
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.00481126
MYOT myotilin -0.00480139
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -0.00479096
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -0.00478021
SLIT2 slit homolog 2 (Drosophila) -0.00477814
SIK1 salt-inducible kinase 1 -0.00476937
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00476083
ENO1 enolase 1, (alpha) -0.00475433
DCSTAMP dendrocyte expressed seven transmembrane protein -0.00474427
P3H2 prolyl 3-hydroxylase 2 -0.00474381
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00473695
NUP58 nucleoporin 58 -0.00473472
DYNLL1 dynein, light chain, LC8-type 1 -0.00469803
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.00468422
LDOC1 leucine zipper, down-regulated in cancer 1 -0.0046736
PRKCZ protein kinase C, zeta -0.00464479
PCYOX1 prenylcysteine oxidase 1 -0.004638
RFC3 replication factor C (activator 1) 3, 38kDa -0.00463674
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -0.0046262
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -0.00462423
GPC4 glypican 4 -0.00461695
GGTLC1 gamma-glutamyltransferase light chain 1 -0.0045662
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00455596
RAP2A RAP2A, member of RAS oncogene family -0.00455324
MYH10 myosin, heavy chain 10, non-muscle -0.0045401
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00453071
TFEC transcription factor EC -0.00452065
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00451404
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00451045
ACO2 aconitase 2, mitochondrial -0.00450288
TNNI1 troponin I type 1 (skeletal, slow) -0.00449084
ACADL acyl-CoA dehydrogenase, long chain -0.00448378
PBX1 pre-B-cell leukemia homeobox 1 -0.00447887
ACTA1 actin, alpha 1, skeletal muscle -0.00447114
PRR11 proline rich 11 -0.00444233
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00443294
TMSB15A thymosin beta 15a -0.00442694
TSPO translocator protein (18kDa) -0.00442217
G6PD glucose-6-phosphate dehydrogenase -0.00442131
LRP2 low density lipoprotein receptor-related protein 2 -0.00441749
DST dystonin -0.00441282
H2AX H2A.X variant histone -0.00440626
KIF20A kinesin family member 20A -0.00439873
CLEC10A C-type lectin domain family 10, member A -0.00437061
EMX2 empty spiracles homeobox 2 -0.00436279
UNC13B unc-13 homolog B (C. elegans) -0.00435171
HLA-DOB major histocompatibility complex, class II, DO beta -0.00435016
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00434135
CENPX centromere protein X -0.00432051
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00430934
PCDH9 protocadherin 9 -0.00430419
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -0.00429652
MAOA monoamine oxidase A -0.00429515
HSPA14 heat shock 70kDa protein 14 -0.00429314
NUP85 nucleoporin 85kDa -0.00428903
FAHD2A fumarylacetoacetate hydrolase domain containing 2A -0.00427496
PTPRD protein tyrosine phosphatase, receptor type, D -0.00427305
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.00427052
MSLN mesothelin -0.00426906
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00426745
RAB33A RAB33A, member RAS oncogene family -0.00426175
NEK2 NIMA-related kinase 2 -0.00425714
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00425297
FANCL Fanconi anemia, complementation group L -0.00424611
MYLIP myosin regulatory light chain interacting protein -0.00424503
PPL periplakin -0.0042413
CLIP3 CAP-GLY domain containing linker protein 3 -0.00423965
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.0042286
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -0.00422446
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.00422271
ENDOD1 endonuclease domain containing 1 -0.00422024
C7 complement component 7 -0.00420829
MEIS2 Meis homeobox 2 -0.00420311
CLDN10 claudin 10 -0.00420164
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00417436
SIVA1 SIVA1, apoptosis-inducing factor -0.0041721
FILIP1L filamin A interacting protein 1-like -0.0041709
ACTC1 actin, alpha, cardiac muscle 1 -0.00416636
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -0.00416603
TESC tescalcin -0.00416288
ALOX15B arachidonate 15-lipoxygenase, type B -0.00415676
BNC2 basonuclin 2 -0.00414787
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00414738
SLC46A3 solute carrier family 46, member 3 -0.00414485
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -0.00414456
BDNF brain-derived neurotrophic factor -0.00414072
TEX261 testis expressed 261 -0.00414023
FGFR1 fibroblast growth factor receptor 1 -0.00413705
ZNF160 zinc finger protein 160 -0.00413283
CCNB1 cyclin B1 -0.00412796
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -0.00411291
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -0.00411244
FOXF1 forkhead box F1 -0.00410933
ZNF512B zinc finger protein 512B -0.00410722
LDB3 LIM domain binding 3 -0.00409976
ADCY9 adenylate cyclase 9 -0.0040972
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) -0.00409701
XYLT1 xylosyltransferase I -0.00408987
NDRG2 NDRG family member 2 -0.0040784
TM6SF1 transmembrane 6 superfamily member 1 -0.00407037
PLXND1 plexin D1 -0.00406978
GCLC glutamate-cysteine ligase, catalytic subunit -0.00406498
FAM172A family with sequence similarity 172, member A -0.00406302
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -0.0040625
CAMK2B calcium/calmodulin-dependent protein kinase II beta -0.0040566