| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | prolyl 4-hydroxylase, alpha polypeptide I|This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5033) |
| External Link | https://ncbi.nlm.nih.gov/gene/5033 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the P4HA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGM2 | transglutaminase 2 | 0.0144393 |
| CHGB | chromogranin B | 0.0140554 |
| WASHC4 | WASH complex subunit 4 | 0.0134709 |
| GNAS | GNAS complex locus | 0.0127058 |
| MGLL | monoglyceride lipase | 0.012631 |
| MAP7 | microtubule-associated protein 7 | 0.0121613 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0115676 |
| COL15A1 | collagen, type XV, alpha 1 | 0.0114764 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.010687 |
| BLNK | B-cell linker | 0.0106681 |
| COQ8A | coenzyme Q8A | 0.0105084 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0104996 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.010266 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.010241 |
| A2M | alpha-2-macroglobulin | 0.0101832 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0101644 |
| RGS5 | regulator of G-protein signaling 5 | 0.0101259 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0100082 |
| FGB | fibrinogen beta chain | 0.00984011 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00979657 |
| TBX2 | T-box 2 | 0.00973146 |
| MED13 | mediator complex subunit 13 | 0.00966032 |
| XPO7 | exportin 7 | 0.00949674 |
| GPATCH8 | G patch domain containing 8 | 0.00939338 |
| VSNL1 | visinin-like 1 | 0.00934604 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00931346 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00931309 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0092931 |
| PCDH9 | protocadherin 9 | 0.00928628 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0092724 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00924287 |
| L1CAM | L1 cell adhesion molecule | 0.00922547 |
| NEBL | nebulette | 0.00920628 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00911386 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00901178 |
| UBXN7 | UBX domain protein 7 | 0.00899876 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.0089715 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00890244 |
| SATB2 | SATB homeobox 2 | 0.0087498 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00862466 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.00857247 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00853234 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00849753 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00847455 |
| FGG | fibrinogen gamma chain | 0.0083875 |
| XYLT1 | xylosyltransferase I | 0.00832761 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.00830339 |
| EGR1 | early growth response 1 | 0.00828306 |
| RGCC | regulator of cell cycle | 0.00828249 |
| KIAA0355 | KIAA0355 | 0.00815225 |
| C1S | complement component 1, s subcomponent | 0.00812483 |
| TNC | tenascin C | 0.00811027 |
| PODXL | podocalyxin-like | 0.00798284 |
| SPRR3 | small proline-rich protein 3 | 0.00793425 |
| TCF4 | transcription factor 4 | 0.00781146 |
| LAMB1 | laminin, beta 1 | 0.00777592 |
| PLAU | plasminogen activator, urokinase | 0.00776084 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00769294 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00767381 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00766789 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00756267 |
| HK2 | hexokinase 2 | 0.00755969 |
| ITGA6 | integrin, alpha 6 | 0.00753488 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.0075207 |
| COL9A3 | collagen, type IX, alpha 3 | 0.00748801 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00747096 |
| FOXN3 | forkhead box N3 | 0.00745689 |
| FGA | fibrinogen alpha chain | 0.0074564 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00741987 |
| NRCAM | neuronal cell adhesion molecule | 0.00740875 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.00739043 |
| EHBP1 | EH domain binding protein 1 | 0.00734551 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00732672 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00727349 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00726912 |
| OLFM1 | olfactomedin 1 | 0.00725123 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00723666 |
| MELK | maternal embryonic leucine zipper kinase | 0.00722702 |
| G0S2 | G0/G1 switch 2 | 0.00719556 |
| TLK2 | tousled-like kinase 2 | 0.00719279 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.00708592 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00704384 |
| CA2 | carbonic anhydrase II | 0.00702044 |
| ABHD17B | abhydrolase domain containing 17B | 0.0070187 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00701618 |
| PALLD | palladin, cytoskeletal associated protein | 0.0069714 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.00696983 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00696863 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00696417 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00695553 |
| PDE8B | phosphodiesterase 8B | 0.00695427 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00695402 |
| FABP7 | fatty acid binding protein 7, brain | 0.0069504 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00693945 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00692846 |
| PRNP | prion protein | 0.00685336 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00685086 |
| NEFM | neurofilament, medium polypeptide | 0.00684372 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0068193 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00681474 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00678976 |
| LPIN1 | lipin 1 | 0.00677024 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00676409 |
| GLA | galactosidase, alpha | 0.00675397 |
| TNS3 | tensin 3 | 0.00672827 |
| IRS2 | insulin receptor substrate 2 | 0.00672645 |
| KIF14 | kinesin family member 14 | 0.00671248 |
| AEBP1 | AE binding protein 1 | 0.00670893 |
| SASH1 | SAM and SH3 domain containing 1 | 0.00670033 |
| CADM1 | cell adhesion molecule 1 | 0.00667301 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00664663 |
| RASA4 | RAS p21 protein activator 4 | 0.00663996 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00662359 |
| RB1 | retinoblastoma 1 | 0.00660629 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00659035 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00658152 |
| CLU | clusterin | 0.00657137 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00655029 |
| PAX5 | paired box 5 | 0.00650814 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.00650794 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00650569 |
| FOXD1 | forkhead box D1 | 0.00649452 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00647343 |
| MX1 | MX dynamin-like GTPase 1 | 0.00647016 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.00646782 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00646428 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.0064225 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00642188 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.00641668 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00640864 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00640591 |
| CDA | cytidine deaminase | 0.00639614 |
| MITF | microphthalmia-associated transcription factor | 0.00638261 |
| SIK1 | salt-inducible kinase 1 | 0.00637848 |
| HCRTR1 | hypocretin (orexin) receptor 1 | 0.00636954 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00632411 |
| RHCG | Rh family, C glycoprotein | 0.00631942 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00631525 |
| RNF130 | ring finger protein 130 | 0.00631298 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00630792 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00629825 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00629393 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00629365 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00627435 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00625906 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.00625705 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00625028 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00623429 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.00622191 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00620409 |
| BAG3 | BCL2-associated athanogene 3 | 0.00619582 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00616465 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00611936 |
| EMP1 | epithelial membrane protein 1 | 0.00609816 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00609659 |
| ADCY1 | adenylate cyclase 1 (brain) | 0.00607708 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00607628 |
| EPS8L2 | EPS8-like 2 | 0.00607 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00605515 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00604911 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | 0.00604339 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00603271 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00602653 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.00602571 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | 0.00602322 |
| CUX1 | cut-like homeobox 1 | 0.00599385 |
| PURA | purine-rich element binding protein A | 0.00599142 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00598789 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00598441 |
| MYLK | myosin light chain kinase | 0.00597573 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00597089 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 | 0.00596809 |
| ZYX | zyxin | 0.0059572 |
| PRDX1 | peroxiredoxin 1 | 0.00595713 |
| ACOT7 | acyl-CoA thioesterase 7 | 0.00595289 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00594925 |
| HLTF | helicase-like transcription factor | 0.00594807 |
| FMR1 | fragile X mental retardation 1 | 0.00594199 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00592948 |
| ABHD2 | abhydrolase domain containing 2 | 0.00592689 |
| KLHL21 | kelch-like family member 21 | 0.00590813 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00590743 |
| PMP22 | peripheral myelin protein 22 | 0.00589704 |
| KLF9 | Kruppel-like factor 9 | 0.00589078 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.00588099 |
| HELZ | helicase with zinc finger | 0.00587911 |
| S100A10 | S100 calcium binding protein A10 | 0.00587882 |
| NMD3 | NMD3 ribosome export adaptor | 0.00586303 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.00585318 |
| HIP1 | huntingtin interacting protein 1 | 0.00584121 |
| RTL8C | retrotransposon Gag like 8C | 0.00583726 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.00583459 |
| LYST | lysosomal trafficking regulator | 0.00582776 |
| PTCH1 | patched 1 | 0.00582245 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00581445 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00580322 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0058012 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00579116 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.00579004 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00577096 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0057664 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00576387 |
| MTF2 | metal response element binding transcription factor 2 | 0.00575841 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00575265 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 | 0.00574695 |
| TUBD1 | tubulin, delta 1 | 0.00574544 |
| ADM | adrenomedullin | 0.0057383 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00573271 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00572825 |
| CD93 | CD93 molecule | 0.00572671 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00572212 |
| TTR | transthyretin | 0.00571184 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00570574 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0056925 |
| GATA2 | GATA binding protein 2 | 0.00568897 |
| FASN | fatty acid synthase | 0.00568771 |
| STX7 | syntaxin 7 | 0.00568627 |
| VWF | von Willebrand factor | 0.0056852 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00568518 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00567956 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00567538 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00566109 |
| CANX | calnexin | 0.00565564 |
| MPDZ | multiple PDZ domain protein | 0.00564122 |
| FAM13B | family with sequence similarity 13, member B | 0.00562496 |
| ACTB | actin, beta | 0.00561913 |
| GPX3 | glutathione peroxidase 3 | 0.00561903 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00561785 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00561443 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00561387 |
| C1R | complement component 1, r subcomponent | 0.00559844 |
| HYAL1 | hyaluronoglucosaminidase 1 | 0.00559217 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00559157 |
| ESRRG | estrogen-related receptor gamma | 0.00558861 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00557692 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00556726 |
| COPS7A | COP9 signalosome subunit 7A | 0.00556639 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00556517 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00556245 |
| PLVAP | plasmalemma vesicle associated protein | 0.00555872 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00555308 |
| IRF8 | interferon regulatory factor 8 | 0.00554743 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00554551 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00554286 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00554163 |
| RAP2C | RAP2C, member of RAS oncogene family | 0.00553581 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00553433 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00553372 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00552876 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.00552763 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -0.0175332 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0161321 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.013959 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0134758 |
| NVL | nuclear VCP-like | -0.0123935 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0120653 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0116868 |
| SELENOW | selenoprotein W | -0.0113543 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0112782 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.0111756 |
| CYBRD1 | cytochrome b reductase 1 | -0.0108412 |
| COL1A2 | collagen, type I, alpha 2 | -0.0107165 |
| ADD3 | adducin 3 (gamma) | -0.0105248 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0103492 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -0.010212 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0101666 |
| LY96 | lymphocyte antigen 96 | -0.00973604 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | -0.00959584 |
| RTN2 | reticulon 2 | -0.00952371 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00944847 |
| ASRGL1 | asparaginase like 1 | -0.00942792 |
| E2F2 | E2F transcription factor 2 | -0.00932713 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00924417 |
| ADI1 | acireductone dioxygenase 1 | -0.00911537 |
| DAPK1 | death-associated protein kinase 1 | -0.00909319 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00899612 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00897567 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00893342 |
| MANSC1 | MANSC domain containing 1 | -0.0089266 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0087554 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00861657 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0085773 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00851344 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00849399 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0084517 |
| COLEC12 | collectin sub-family member 12 | -0.00842694 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00840051 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00834059 |
| ZNF593 | zinc finger protein 593 | -0.00831765 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00830089 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00823711 |
| PIP | prolactin-induced protein | -0.00822065 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00817869 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00813165 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.0080273 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00801486 |
| WBP5 | WW domain binding protein 5 | -0.0079827 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00795512 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00794492 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00792106 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00786749 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00784743 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00784667 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00783983 |
| MLPH | melanophilin | -0.00780531 |
| SST | somatostatin | -0.00780275 |
| FST | follistatin | -0.00779252 |
| ANXA3 | annexin A3 | -0.00772208 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00760792 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00757555 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00757466 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00754687 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00748364 |
| FCGBP | Fc fragment of IgG binding protein | -0.00748213 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00748049 |
| SPAG16 | sperm associated antigen 16 | -0.00744893 |
| TMEM14B | transmembrane protein 14B | -0.0074352 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00743278 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00740595 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00738505 |
| XIC | X chromosome inactivation center | -0.00737633 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.007362 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00731704 |
| MYBPC2 | myosin binding protein C, fast type | -0.0072772 |
| THYN1 | thymocyte nuclear protein 1 | -0.00712717 |
| PKP4 | plakophilin 4 | -0.00709902 |
| CHMP4A | charged multivesicular body protein 4A | -0.0070951 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00700861 |
| PYCARD | PYD and CARD domain containing | -0.00699676 |
| MYL5 | myosin, light chain 5, regulatory | -0.00698978 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00697401 |
| CLGN | calmegin | -0.0069653 |
| NSG1 | neuron specific gene family member 1 | -0.00696418 |
| PDGFC | platelet derived growth factor C | -0.00695758 |
| GCH1 | GTP cyclohydrolase 1 | -0.0069213 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00691299 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00688647 |
| NRN1 | neuritin 1 | -0.00687613 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00685489 |
| LYRM4 | LYR motif containing 4 | -0.00683746 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00682796 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00681963 |
| SIRT5 | sirtuin 5 | -0.00680993 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00680985 |
| PLA2G12A | phospholipase A2, group XIIA | -0.00680936 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00679459 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00677636 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00675056 |
| B9D1 | B9 protein domain 1 | -0.00672295 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00671967 |
| MLF1 | myeloid leukemia factor 1 | -0.00670862 |
| RESF1 | retroelement silencing factor 1 | -0.00666117 |
| CHN2 | chimerin 2 | -0.00665965 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | -0.00661912 |
| SLFN12 | schlafen family member 12 | -0.00659913 |
| VNN1 | vanin 1 | -0.0065912 |
| DCLK1 | doublecortin-like kinase 1 | -0.00657862 |
| KLK5 | kallikrein-related peptidase 5 | -0.006574 |
| NCALD | neurocalcin delta | -0.00652682 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00652407 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00650401 |
| CDC42 | cell division cycle 42 | -0.0065012 |
| UROS | uroporphyrinogen III synthase | -0.00647124 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00645821 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | -0.0064492 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00642185 |
| GMPR | guanosine monophosphate reductase | -0.00640986 |
| C3AR1 | complement component 3a receptor 1 | -0.00639597 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00638507 |
| EPCAM | epithelial cell adhesion molecule | -0.00636336 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00635925 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00634109 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00632931 |
| LRRC17 | leucine rich repeat containing 17 | -0.00631315 |
| UROD | uroporphyrinogen decarboxylase | -0.00631189 |
| TMOD1 | tropomodulin 1 | -0.00630852 |
| CD320 | CD320 molecule | -0.00630488 |
| THAP12 | THAP domain containing 12 | -0.00628648 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0062745 |
| GPC4 | glypican 4 | -0.00626649 |
| LGMN | legumain | -0.00625386 |
| CD300A | CD300a molecule | -0.00625015 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00623664 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | -0.00623054 |
| TMC5 | transmembrane channel-like 5 | -0.00622498 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00622131 |
| C11ORF49 | chromosome 11 open reading frame 49 | -0.00620943 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00619011 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00616247 |
| BID | BH3 interacting domain death agonist | -0.00616043 |
| SIX2 | SIX homeobox 2 | -0.00615736 |
| FPR1 | formyl peptide receptor 1 | -0.00614908 |
| KIF1A | kinesin family member 1A | -0.00613543 |
| TBXAS1 | thromboxane A synthase 1 (platelet) | -0.00608681 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.0060854 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00607914 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.0060654 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00602569 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | -0.00601446 |
| PSPH | phosphoserine phosphatase | -0.00600218 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | -0.00598991 |
| PFDN5 | prefoldin subunit 5 | -0.00597584 |
| TSPYL5 | TSPY-like 5 | -0.00597375 |
| GIMAP4 | GTPase, IMAP family member 4 | -0.0059703 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00596408 |
| MAP3K7CL | MAP3K7 C-terminal like | -0.00595845 |
| SRGN | serglycin | -0.0059561 |
| MYBPC1 | myosin binding protein C, slow type | -0.0059511 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00594511 |
| NINJ2 | ninjurin 2 | -0.00592675 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00591804 |
| KLF2 | Kruppel-like factor 2 | -0.00590929 |
| MEA1 | male-enhanced antigen 1 | -0.00589885 |
| APOC1 | apolipoprotein C-I | -0.00586956 |
| BCL2A1 | BCL2-related protein A1 | -0.00586736 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00586521 |
| POLR2G | polymerase (RNA) II (DNA directed) polypeptide G | -0.00586498 |
| TEX30 | testis expressed 30 | -0.00586004 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00585303 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00584339 |
| SHTN1 | shootin 1 | -0.00584014 |
| SMYD2 | SET and MYND domain containing 2 | -0.00582321 |
| IQCG | IQ motif containing G | -0.00580483 |
| CCDC28B | coiled-coil domain containing 28B | -0.00576614 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | -0.00575685 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.00574853 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | -0.00574787 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00574422 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.00574414 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00573714 |
| CLIC1 | chloride intracellular channel 1 | -0.00573164 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00572802 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00571279 |
| SMAD6 | SMAD family member 6 | -0.00569398 |
| RCAN1 | regulator of calcineurin 1 | -0.0056903 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00568852 |
| ADSL | adenylosuccinate lyase | -0.0056876 |
| LY6H | lymphocyte antigen 6 complex, locus H | -0.00568347 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | -0.00567794 |
| SCG5 | secretogranin V | -0.00567171 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0056691 |
| HPSE | heparanase | -0.00565923 |
| AAGAB | alpha- and gamma-adaptin binding protein | -0.005651 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.00564367 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00562176 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00561435 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00558849 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00556742 |
| FOXG1 | forkhead box G1 | -0.00556668 |
| NTS | neurotensin | -0.00556486 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.00554607 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00554088 |
| SMYD3 | SET and MYND domain containing 3 | -0.00554067 |
| SOX17 | SRY (sex determining region Y)-box 17 | -0.00552541 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 | -0.00552108 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00551506 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00551347 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00547887 |
| CLC | Charcot-Leyden crystal galectin | -0.00547566 |
| GPX1 | glutathione peroxidase 1 | -0.00547526 |
| GPR88 | G protein-coupled receptor 88 | -0.00545338 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00544872 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00542463 |
| HIKESHI | heat shock protein nuclear import factor hikeshi | -0.00541533 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00541416 |
| CFI | complement factor I | -0.00541283 |
| ACP3 | acid phosphatase 3 | -0.00540787 |
| MEIS2 | Meis homeobox 2 | -0.00540747 |
| ADRA2A | adrenoceptor alpha 2A | -0.00540019 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00539666 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00539659 |
| THBS1 | thrombospondin 1 | -0.00539547 |
| PENK | proenkephalin | -0.00538392 |
| MRPL11 | mitochondrial ribosomal protein L11 | -0.0053679 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00536733 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00536387 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00536077 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00535992 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.00535105 |
| EFNB2 | ephrin-B2 | -0.00533729 |
| ZNF274 | zinc finger protein 274 | -0.0053225 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 | -0.00531691 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00531254 |
| TSPAN15 | tetraspanin 15 | -0.00531203 |
| SIX1 | SIX homeobox 1 | -0.00530743 |
| HRASLS | HRAS-like suppressor | -0.00530736 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00529985 |
| RPIA | ribose 5-phosphate isomerase A | -0.005278 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00527572 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00527078 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00525283 |
| MAGED1 | melanoma antigen family D1 | -0.0052511 |
| ANO3 | anoctamin 3 | -0.0052451 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00524224 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00523951 |
| SNAP23 | synaptosomal-associated protein, 23kDa | -0.00522502 |
| MED7 | mediator complex subunit 7 | -0.00521312 |
| TMEM106C | transmembrane protein 106C | -0.00520824 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00519934 |
| LST1 | leukocyte specific transcript 1 | -0.00518683 |
