P4HA1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description prolyl 4-hydroxylase, alpha polypeptide I|This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5033)
External Link http://www.ncbi.nlm.nih.gov/gene/5033
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Genes

374 interacting proteins for P4HA1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
AASS aminoadipate-semialdehyde synthase
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACOT8 acyl-CoA thioesterase 8
ACP2 acid phosphatase 2, lysosomal
ACTL6A actin-like 6A
ADGRE5 adhesion G protein-coupled receptor E5
ADNP activity-dependent neuroprotector homeobox
AIP aryl hydrocarbon receptor interacting protein
AKAP8 A kinase (PRKA) anchor protein 8
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
APMAP adipocyte plasma membrane associated protein
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARF4 ADP-ribosylation factor 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL1 ADP-ribosylation factor-like 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASS1 argininosuccinate synthase 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BCR breakpoint cluster region
BIN1 bridging integrator 1
BSG basigin (Ok blood group)
BTD biotinidase
BTN2A1 butyrophilin, subfamily 2, member A1
C1QBP complement component 1, q subcomponent binding protein
CACYBP calcyclin binding protein
CALU calumenin
CCDC47 coiled-coil domain containing 47
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD109 CD109 molecule
CD276 CD276 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CDK1 cyclin-dependent kinase 1
CDK9 cyclin-dependent kinase 9
CEPT1 choline/ethanolamine phosphotransferase 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHD4 chromodomain helicase DNA binding protein 4
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CLN5 ceroid-lipofuscinosis, neuronal 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLU clusterin
COL5A1 collagen, type V, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COPB1 coatomer protein complex, subunit beta 1
COPG1 coatomer protein complex, subunit gamma 1
COPG2 coatomer protein complex, subunit gamma 2
CRTAP cartilage associated protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSB cathepsin B
CTSD cathepsin D
CUL3 cullin 3
CYR61 cysteine-rich, angiogenic inducer, 61
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNASE2 deoxyribonuclease II, lysosomal
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPP7 dipeptidyl-peptidase 7
DSG1 desmoglein 1
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
ECE1 endothelin converting enzyme 1
EEF1G eukaryotic translation elongation factor 1 gamma
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELAVL1 ELAV like RNA binding protein 1
EMC1 ER membrane protein complex subunit 1
EP400 E1A binding protein p400
ERCC3 excision repair cross-complementation group 3
ERO1L ERO1-like (S. cerevisiae)
ETFA electron-transfer-flavoprotein, alpha polypeptide
EYS eyes shut homolog (Drosophila)
FAM27E3 family with sequence similarity 27, member E3
FANCD2 Fanconi anemia, complementation group D2
FBL fibrillarin
FBN1 fibrillin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FKBP9 FK506 binding protein 9, 63 kDa
FOLR1 folate receptor 1 (adult)
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GAA glucosidase, alpha; acid
GANAB glucosidase, alpha; neutral AB
GBA glucosidase, beta, acid
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCDH glutaryl-CoA dehydrogenase
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GLMP glycosylated lysosomal membrane protein
GNS glucosamine (N-acetyl)-6-sulfatase
GPRASP2 G protein-coupled receptor associated sorting protein 2
GSG2 germ cell associated 2 (haspin)
GTF2I general transcription factor IIi
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
GUSB glucuronidase, beta
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HDAC1 histone deacetylase 1
HDAC10 histone deacetylase 10
HDAC2 histone deacetylase 2
HELLS helicase, lymphoid-specific
HEXA hexosaminidase A (alpha polypeptide)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIST1H2BL histone cluster 1, H2bl
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSPA13 heat shock protein 70kDa family, member 13
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
HYOU1 hypoxia up-regulated 1
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2R insulin-like growth factor 2 receptor
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ILVBL ilvB (bacterial acetolactate synthase)-like
IPO13 importin 13
IPO4 importin 4
IPO7 importin 7
IPO9 importin 9
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
IQSEC1 IQ motif and Sec7 domain 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRF7 interferon regulatory factor 7
IRS4 insulin receptor substrate 4
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
L1CAM L1 cell adhesion molecule
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNA lamin A/C
LNPEP leucyl/cystinyl aminopeptidase
LONP1 lon peptidase 1, mitochondrial
LRPPRC leucine-rich pentatricopeptide repeat containing
LTN1 listerin E3 ubiquitin protein ligase 1
M6PR mannose-6-phosphate receptor (cation dependent)
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MAN2B1 mannosidase, alpha, class 2B, member 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARS methionyl-tRNA synthetase
MAX MYC associated factor X
MCM7 minichromosome maintenance complex component 7
MLF2 myeloid leukemia factor 2
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MOGS mannosyl-oligosaccharide glucosidase
MRPS22 mitochondrial ribosomal protein S22
MRPS34 mitochondrial ribosomal protein S34
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
MYO9A myosin IXA
MYO9B myosin IXB
NCEH1 neutral cholesterol ester hydrolase 1
NCSTN nicastrin
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NEK9 NIMA-related kinase 9
NISCH nischarin
NOMO1 NODAL modulator 1
NONO non-POU domain containing, octamer-binding
NOP56 NOP56 ribonucleoprotein
NPC1 Niemann-Pick disease, type C1
NRF1 nuclear respiratory factor 1
NUCLEOLIN nucleolin multifunctional protein
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP210 nucleoporin 210kDa
OAT ornithine aminotransferase
P3H1 prolyl 3-hydroxylase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PALD1 phosphatase domain containing, paladin 1
PCBP1 poly(rC) binding protein 1
PCYOX1 prenylcysteine oxidase 1
PDIA3 protein disulfide isomerase family A, member 3
PELO pelota homolog (Drosophila)
PIGR polymeric immunoglobulin receptor
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLA2G15 phospholipase A2, group XV
PLK1 polo-like kinase 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXNB2 plexin B2
PODXL2 podocalyxin-like 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPF6 pre-mRNA processing factor 6
PSAP prosaposin
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSME4 proteasome (prosome, macropain) activator subunit 4
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PXN paxillin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP2 RAN binding protein 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNGTT RNA guanylyltransferase and 5'-phosphatase
RNH1 ribonuclease/angiogenin inhibitor 1
RPN1 ribophorin I
RPN2 ribophorin II
RPP30 ribonuclease P/MRP 30kDa subunit
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SARS seryl-tRNA synthetase
SCARB1 scavenger receptor class B, member 1
SCARB2 scavenger receptor class B, member 2
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETD3 SET domain containing 3
SGSH N-sulfoglucosamine sulfohydrolase
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIAE sialic acid acetylesterase
SKP1 S-phase kinase-associated protein 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLIT2 slit homolog 2 (Drosophila)
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC2 structural maintenance of chromosomes 2
SMC4 structural maintenance of chromosomes 4
SMN2 survival of motor neuron 2, centromeric
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQRDL sulfide quinone reductase-like (yeast)
SQSTM1 sequestosome 1
SSR1 signal sequence receptor, alpha
SSR4 signal sequence receptor, delta
STOM stomatin
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUCLG1 succinate-CoA ligase, alpha subunit
SUMF1 sulfatase modifying factor 1
SUN2 Sad1 and UNC84 domain containing 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCP1 t-complex 1
TFRC transferrin receptor
TLK2 tousled-like kinase 2
TMPO thymopoietin
TMX3 thioredoxin-related transmembrane protein 3
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TPBG trophoblast glycoprotein
TPP1 tripeptidyl peptidase I
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM28 tripartite motif containing 28
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRMT61B tRNA methyltransferase 61B
TRRAP transformation/transcription domain-associated protein
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC27 tetratricopeptide repeat domain 27
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TUBB6 tubulin, beta 6 class V
TUBG1 tubulin, gamma 1
TUBGCP2 tubulin, gamma complex associated protein 2
TXNDC15 thioredoxin domain containing 15
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
U2SURP U2 snRNP-associated SURP domain containing
UBC ubiquitin C
UBE3C ubiquitin protein ligase E3C
UBL4A ubiquitin-like 4A
UBR2 ubiquitin protein ligase E3 component n-recognin 2
USP9X ubiquitin specific peptidase 9, X-linked
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
WDR6 WD repeat domain 6
WDR77 WD repeat domain 77
WWOX WW domain containing oxidoreductase
XPO1 exportin 1
XPO5 exportin 5
XPOT exportin, tRNA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN1 5'-3' exoribonuclease 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF121 zinc finger protein 121
ZNF281 zinc finger protein 281