| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | prolyl 4-hydroxylase, alpha polypeptide II|This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8974) |
| External Link | https://ncbi.nlm.nih.gov/gene/8974 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the P4HA2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 0.0146467 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0114045 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.0101589 |
| CLU | clusterin | 0.00819733 |
| LTF | lactotransferrin | 0.00801571 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00724001 |
| NRCAM | neuronal cell adhesion molecule | 0.00694135 |
| ATF3 | activating transcription factor 3 | 0.0069044 |
| S100A8 | S100 calcium binding protein A8 | 0.00682403 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00655117 |
| MAP7 | microtubule-associated protein 7 | 0.00649193 |
| MMP9 | matrix metallopeptidase 9 | 0.00637862 |
| MAGEA3 | melanoma antigen family A3 | 0.00633824 |
| XIC | X chromosome inactivation center | 0.00629545 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00611256 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00604365 |
| PEG10 | paternally expressed 10 | 0.0059401 |
| S100A9 | S100 calcium binding protein A9 | 0.00588694 |
| KLHL24 | kelch-like family member 24 | 0.00577916 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00571672 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00566678 |
| CD9 | CD9 molecule | 0.0056549 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00564937 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00560802 |
| CORO1A | coronin, actin binding protein, 1A | 0.0055469 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00551101 |
| HMOX1 | heme oxygenase 1 | 0.00548321 |
| PSAP | prosaposin | 0.00541601 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.0053446 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00533448 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00530518 |
| PLPP3 | phospholipid phosphatase 3 | 0.00530105 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00529695 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00528039 |
| MCL1 | myeloid cell leukemia 1 | 0.00523099 |
| PCDH9 | protocadherin 9 | 0.00521405 |
| NEFM | neurofilament, medium polypeptide | 0.00520813 |
| DACH1 | dachshund family transcription factor 1 | 0.00518126 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00515659 |
| PCP4 | Purkinje cell protein 4 | 0.00513068 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00512098 |
| PLBD1 | phospholipase B domain containing 1 | 0.00503724 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00500667 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00498958 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00496521 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00493754 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00492123 |
| CLDN4 | claudin 4 | 0.00489824 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00486674 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00482949 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00478556 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00477786 |
| IDS | iduronate 2-sulfatase | 0.00474242 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00473143 |
| RND3 | Rho family GTPase 3 | 0.00469849 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00469423 |
| CSTA | cystatin A (stefin A) | 0.00469037 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00468122 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 | 0.00467972 |
| SGCE | sarcoglycan, epsilon | 0.00465701 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | 0.00459454 |
| CLDN7 | claudin 7 | 0.00457027 |
| PERP | PERP, TP53 apoptosis effector | 0.00455781 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00454719 |
| BTG2 | BTG family, member 2 | 0.00449824 |
| CLDN3 | claudin 3 | 0.00449644 |
| ASS1 | argininosuccinate synthase 1 | 0.00449442 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00448387 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00447897 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00446997 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00446177 |
| G0S2 | G0/G1 switch 2 | 0.00441747 |
| KRT23 | keratin 23, type I | 0.00439439 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0043774 |
| ZNF91 | zinc finger protein 91 | 0.00434648 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00434127 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00433873 |
| EFNB2 | ephrin-B2 | 0.00430343 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00428087 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.00426799 |
| MMD | monocyte to macrophage differentiation-associated | 0.0042491 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00423571 |
| NCBP2 | nuclear cap binding protein subunit 2, 20kDa | 0.00422478 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00421329 |
| LCN2 | lipocalin 2 | 0.00419758 |
| STAB1 | stabilin 1 | 0.00419375 |
| RIN2 | Ras and Rab interactor 2 | 0.00417316 |
| MVP | major vault protein | 0.00416221 |
| JUNB | jun B proto-oncogene | 0.00414878 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0041454 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.00414113 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00413684 |
| TBX3 | T-box 3 | 0.0041181 |
| BEX4 | brain expressed, X-linked 4 | 0.00410672 |
| NEBL | nebulette | 0.00409656 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.00409491 |
| CD52 | CD52 molecule | 0.0040948 |
| CD163 | CD163 molecule | 0.00408842 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00408243 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00408238 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00407801 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00406934 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00406397 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00405899 |
| DUSP5 | dual specificity phosphatase 5 | 0.00405349 |
| DNM1L | dynamin 1-like | 0.00404158 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00403536 |
| ACKR3 | atypical chemokine receptor 3 | 0.00400343 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00400143 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00396953 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00393994 |
| ANGPT1 | angiopoietin 1 | 0.00392435 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00391072 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.00390488 |
| FRMD4B | FERM domain containing 4B | 0.00390357 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00389527 |
| PRSS3 | protease, serine, 3 | 0.00389336 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00389036 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00388464 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00384647 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00384301 |
| CCDC6 | coiled-coil domain containing 6 | 0.00383433 |
| RIT1 | Ras-like without CAAX 1 | 0.00382851 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0038127 |
| ANK2 | ankyrin 2, neuronal | 0.00380991 |
| CAST | calpastatin | 0.00380388 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.00379885 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00379849 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0037964 |
| PDE8B | phosphodiesterase 8B | 0.00378585 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00375544 |
| CCNA2 | cyclin A2 | 0.0037412 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00373631 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00373288 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00373153 |
| TSPYL5 | TSPY-like 5 | 0.0037173 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00371077 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.003707 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | 0.00370666 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00369856 |
| PRPF18 | pre-mRNA processing factor 18 | 0.00369815 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00369415 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00368757 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00368483 |
| PTHLH | parathyroid hormone-like hormone | 0.00368388 |
| ADIRF | adipogenesis regulatory factor | 0.00367187 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.00366773 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00366576 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00366242 |
| INTS6 | integrator complex subunit 6 | 0.00365646 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.00365347 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) | 0.0036356 |
| DPEP1 | dipeptidase 1 (renal) | 0.00362205 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00361431 |
| KRT14 | keratin 14, type I | 0.00360531 |
| SORT1 | sortilin 1 | 0.00360032 |
| ARF3 | ADP-ribosylation factor 3 | 0.00358338 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00358156 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00357725 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00357541 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00357151 |
| CHI3L2 | chitinase 3-like 2 | 0.00356829 |
| LYPLA1 | lysophospholipase I | 0.00356753 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00356316 |
| GSDMB | gasdermin B | 0.00356057 |
| SELE | selectin E | 0.00354952 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.00354902 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0035478 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.00354689 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00354518 |
| FGL2 | fibrinogen-like 2 | 0.00352583 |
| ICAM2 | intercellular adhesion molecule 2 | 0.003518 |
| GCH1 | GTP cyclohydrolase 1 | 0.00351793 |
| INHBB | inhibin, beta B | 0.00351322 |
| DDA1 | DET1 and DDB1 associated 1 | 0.00350653 |
| CALB1 | calbindin 1, 28kDa | 0.00350029 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | 0.00350025 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 0.00348887 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00348382 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00348017 |
| ZNF430 | zinc finger protein 430 | 0.00347423 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00347123 |
| RCAN2 | regulator of calcineurin 2 | 0.00346661 |
| AUTS2 | autism susceptibility candidate 2 | 0.00346217 |
| ABHD11 | abhydrolase domain containing 11 | 0.00343895 |
| SVIL | supervillin | 0.00343633 |
| NXN | nucleoredoxin | 0.00342813 |
| KLF6 | Kruppel-like factor 6 | 0.0034226 |
| ZIC1 | Zic family member 1 | 0.00342214 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00341862 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00341461 |
| FST | follistatin | 0.00340112 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00339262 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0033895 |
| RGS16 | regulator of G-protein signaling 16 | 0.00338806 |
| GPATCH2 | G patch domain containing 2 | 0.00338299 |
| EGR1 | early growth response 1 | 0.00338178 |
| KLF11 | Kruppel-like factor 11 | 0.00338148 |
| UPP1 | uridine phosphorylase 1 | 0.00338143 |
| ZNF117 | zinc finger protein 117 | 0.00337506 |
| TLK2 | tousled-like kinase 2 | 0.00336859 |
| OGA | O-GlcNAcase | 0.00336652 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00336564 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00336437 |
| ABHD4 | abhydrolase domain containing 4 | 0.00336374 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00335941 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00335784 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00334718 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.00334186 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00332785 |
| TSPAN15 | tetraspanin 15 | 0.00332257 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0033205 |
| PON2 | paraoxonase 2 | 0.00331418 |
| ZNF43 | zinc finger protein 43 | 0.00331128 |
| VWF | von Willebrand factor | 0.00330454 |
| HTRA1 | HtrA serine peptidase 1 | 0.00330166 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00329311 |
| CHODL | chondrolectin | 0.00328356 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00328265 |
| MT1M | metallothionein 1M | 0.00327538 |
| WLS | wntless Wnt ligand secretion mediator | 0.00327196 |
| SRPK2 | SRSF protein kinase 2 | 0.00327005 |
| CCNG2 | cyclin G2 | 0.00326918 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00326742 |
| MAX | MYC associated factor X | 0.00326527 |
| MEF2C | myocyte enhancer factor 2C | 0.00326126 |
| SRGN | serglycin | 0.00325085 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00324859 |
| NCDN | neurochondrin | 0.00324204 |
| AREG | amphiregulin | 0.00324025 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00323237 |
| RNF19B | ring finger protein 19B | 0.00323127 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00322104 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00321974 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.0032175 |
| TYMP | thymidine phosphorylase | 0.00321329 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00320643 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00319788 |
| TAC1 | tachykinin, precursor 1 | 0.00319557 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 0.00319244 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00318601 |
| PENK | proenkephalin | 0.00316811 |
| CGGBP1 | CGG triplet repeat binding protein 1 | 0.00316729 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00316041 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00315901 |
| CTSB | cathepsin B | 0.00315298 |
| EVI2A | ecotropic viral integration site 2A | 0.00315258 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.00315072 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0111202 |
| KIF20A | kinesin family member 20A | -0.00716982 |
| NPTX2 | neuronal pentraxin II | -0.00653618 |
| ANOS1 | anosmin 1 | -0.00636671 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.0062908 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00617417 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00593763 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00573756 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00570179 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00554747 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00552764 |
| MDFIC | MyoD family inhibitor domain containing | -0.00542458 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0054162 |
| TGM2 | transglutaminase 2 | -0.005384 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00533712 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00532537 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00526615 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00510935 |
| RNF130 | ring finger protein 130 | -0.00509001 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00496921 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0049477 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00492974 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0049263 |
| AXL | AXL receptor tyrosine kinase | -0.00484563 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00484519 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.00482301 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.00481141 |
| MFAP5 | microfibrillar associated protein 5 | -0.00462213 |
| TLCD3A | TLC domain containing 3A | -0.00458427 |
| COPS7A | COP9 signalosome subunit 7A | -0.00449066 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00447642 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00446718 |
| TNC | tenascin C | -0.00445982 |
| OIP5 | Opa interacting protein 5 | -0.00444737 |
| SFTPA2 | surfactant protein A2 | -0.00443694 |
| MYO5C | myosin VC | -0.00438307 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00435851 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00434373 |
| PIH1D1 | PIH1 domain containing 1 | -0.00433864 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.00432708 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00429788 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | -0.00427037 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.00427003 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00424764 |
| GAS1 | growth arrest-specific 1 | -0.00422994 |
| C4BPA | complement component 4 binding protein, alpha | -0.00422938 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00422423 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00421734 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0042022 |
| SFTPD | surfactant protein D | -0.00419291 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00417328 |
| MLH1 | mutL homolog 1 | -0.00417189 |
| SEPTIN10 | septin 10 | -0.00411737 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00406643 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00405407 |
| RNASET2 | ribonuclease T2 | -0.00402957 |
| LOX | lysyl oxidase | -0.00400179 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00396216 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00396097 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00395537 |
| PHB2 | prohibitin 2 | -0.00394187 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00393248 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00393036 |
| PCNA | proliferating cell nuclear antigen | -0.00391437 |
| NLGN4X | neuroligin 4, X-linked | -0.00390851 |
| PURA | purine-rich element binding protein A | -0.00390644 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00389884 |
| CA9 | carbonic anhydrase IX | -0.00389039 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.00381778 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0038116 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00380782 |
| DAPK1 | death-associated protein kinase 1 | -0.00380576 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00380059 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00379216 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.0037912 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00378865 |
| NDNF | neuron-derived neurotrophic factor | -0.00378279 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00378107 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | -0.0037383 |
| CDC25C | cell division cycle 25C | -0.00373764 |
| MNS1 | meiosis-specific nuclear structural 1 | -0.00373654 |
| CCNG1 | cyclin G1 | -0.00373506 |
| CLDN10 | claudin 10 | -0.00371989 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00371708 |
| PLK1 | polo-like kinase 1 | -0.00371663 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | -0.00370783 |
| STK10 | serine/threonine kinase 10 | -0.00369649 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00368506 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00368425 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00368191 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -0.00367082 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00365828 |
| FAM3C | family with sequence similarity 3, member C | -0.00364989 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | -0.00364863 |
| APEH | acylaminoacyl-peptide hydrolase | -0.00362461 |
| SNX24 | sorting nexin 24 | -0.00361152 |
| HDAC3 | histone deacetylase 3 | -0.00360966 |
| DOK5 | docking protein 5 | -0.00359688 |
| COMP | cartilage oligomeric matrix protein | -0.0035936 |
| TOX3 | TOX high mobility group box family member 3 | -0.00358993 |
| KIF23 | kinesin family member 23 | -0.00358521 |
| HDAC6 | histone deacetylase 6 | -0.00357257 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0035621 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00356013 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00355052 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00353679 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.00352033 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00351412 |
| ANXA10 | annexin A10 | -0.00348392 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.00348022 |
| INSIG2 | insulin induced gene 2 | -0.00347171 |
| CDCA3 | cell division cycle associated 3 | -0.00346829 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00346763 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00345544 |
| CP | ceruloplasmin (ferroxidase) | -0.00345359 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | -0.00344744 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 | -0.00344722 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | -0.00344533 |
| WT1 | Wilms tumor 1 | -0.00344021 |
| SDC2 | syndecan 2 | -0.00343675 |
| PIMREG | PICALM interacting mitotic regulator | -0.00343574 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.00342166 |
| TMEM255A | transmembrane protein 255A | -0.00341991 |
| CRYM | crystallin, mu | -0.00341494 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00341465 |
| PGC | progastricsin (pepsinogen C) | -0.00340953 |
| FTSJ1 | FtsJ RNA methyltransferase homolog 1 (E. coli) | -0.00340749 |
| TCTN1 | tectonic family member 1 | -0.00340702 |
| TLR4 | toll-like receptor 4 | -0.00340367 |
| SFTPB | surfactant protein B | -0.00338552 |
| B3GNT1 | -0.00338352 | |
| CBFB | core-binding factor, beta subunit | -0.00338154 |
| ETV5 | ets variant 5 | -0.00336701 |
| KIF15 | kinesin family member 15 | -0.0033622 |
| PRKD3 | protein kinase D3 | -0.00335594 |
| CDH13 | cadherin 13 | -0.00335563 |
| C3 | complement component 3 | -0.00335413 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00334821 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.00334496 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00333943 |
| TMSB15A | thymosin beta 15a | -0.00333638 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00333518 |
| XYLT1 | xylosyltransferase I | -0.00333493 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00333182 |
| UBL3 | ubiquitin-like 3 | -0.00332053 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.0033131 |
| ESR1 | estrogen receptor 1 | -0.0033125 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00329887 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | -0.00328964 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.00327547 |
| DCK | deoxycytidine kinase | -0.00326886 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00326647 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00326 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0032577 |
| MSRA | methionine sulfoxide reductase A | -0.00324515 |
| CFI | complement factor I | -0.00324154 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -0.00323308 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00323186 |
| CTSE | cathepsin E | -0.00322401 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00321955 |
| SRSF6 | serine/arginine-rich splicing factor 6 | -0.00321738 |
| MIA3 | melanoma inhibitory activity family, member 3 | -0.00321393 |
| MYD88 | myeloid differentiation primary response 88 | -0.00321055 |
| DIAPH1 | diaphanous-related formin 1 | -0.00321031 |
| ODAM | odontogenic, ameloblast asssociated | -0.00320741 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00320406 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00319899 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00319832 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00319745 |
| CDC45 | cell division cycle 45 | -0.00317832 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00317737 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00317049 |
| FBXO5 | F-box protein 5 | -0.00316974 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.00316943 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | -0.00316649 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00315792 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00314284 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00313696 |
| TMCO6 | transmembrane and coiled-coil domains 6 | -0.00313217 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00313114 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.00312839 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.00312403 |
| KARS1 | lysyl-tRNA synthetase 1 | -0.00312397 |
| FTO | fat mass and obesity associated | -0.00311352 |
| GLO1 | glyoxalase I | -0.00310926 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00310533 |
| MAST2 | microtubule associated serine/threonine kinase 2 | -0.0031018 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.0031009 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00309478 |
| FERMT1 | fermitin family member 1 | -0.00309361 |
| UNC13B | unc-13 homolog B (C. elegans) | -0.00309134 |
| KRT18 | keratin 18, type I | -0.00308956 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00308916 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.0030789 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.00307683 |
| RRM1 | ribonucleotide reductase M1 | -0.00307058 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00305712 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00305702 |
| RPL29 | ribosomal protein L29 | -0.00305658 |
| DPP8 | dipeptidyl-peptidase 8 | -0.00305636 |
| ATP10D | ATPase, class V, type 10D | -0.00305607 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.00305179 |
| FGF9 | fibroblast growth factor 9 | -0.00304731 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.00304358 |
| EPYC | epiphycan | -0.00303815 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -0.00303791 |
| LTA4H | leukotriene A4 hydrolase | -0.00302999 |
| FBL | fibrillarin | -0.00302005 |
| HOXC10 | homeobox C10 | -0.00301761 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00301736 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00301623 |
| TMEM131 | transmembrane protein 131 | -0.00301289 |
| FGG | fibrinogen gamma chain | -0.00301065 |
| HYAL1 | hyaluronoglucosaminidase 1 | -0.00300639 |
| HELLS | helicase, lymphoid-specific | -0.00300007 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00299874 |
| VBP1 | von Hippel-Lindau binding protein 1 | -0.00299346 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00299257 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00299067 |
| SLC2A4RG | SLC2A4 regulator | -0.00298386 |
| DHPS | deoxyhypusine synthase | -0.00298181 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00297406 |
| CA2 | carbonic anhydrase II | -0.00296908 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.00296805 |
| CENPE | centromere protein E, 312kDa | -0.00296282 |
| PRKCB | protein kinase C, beta | -0.00296173 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.00295999 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00295757 |
| LACTB2 | lactamase, beta 2 | -0.00295081 |
| HP | haptoglobin | -0.00294648 |
| KIF18B | kinesin family member 18B | -0.00293751 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00293555 |
| UNG | uracil-DNA glycosylase | -0.00292813 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00292733 |
| NCAPG | non-SMC condensin I complex, subunit G | -0.00292629 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.0029259 |
| BEX1 | brain expressed, X-linked 1 | -0.00292351 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00291631 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00291195 |
| RPL10 | ribosomal protein L10 | -0.00290901 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 | -0.00289971 |
| TP53 | tumor protein p53 | -0.00289205 |
| MKKS | McKusick-Kaufman syndrome | -0.00288712 |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) | -0.00288459 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 | -0.00288336 |
| SLAMF7 | SLAM family member 7 | -0.00288016 |
| PRTN3 | proteinase 3 | -0.00287378 |
| TARDBP | TAR DNA binding protein | -0.00286991 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.00286531 |
| NCAPH | non-SMC condensin I complex, subunit H | -0.00286275 |
