P4HA2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description prolyl 4-hydroxylase, alpha polypeptide II|This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8974)
External Link http://www.ncbi.nlm.nih.gov/gene/8974
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Genes

271 interacting proteins for P4HA2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABHD10 abhydrolase domain containing 10
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ALB albumin
ALDOA aldolase A, fructose-bisphosphate
ALYREF Aly/REF export factor
ANXA2 annexin A2
ANXA5 annexin A5
APOA1BP apolipoprotein A-I binding protein
BAG2 BCL2-associated athanogene 2
BIN1 bridging integrator 1
BTF3 basic transcription factor 3
CACYBP calcyclin binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CALU calumenin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDC37 cell division cycle 37
CDK1 cyclin-dependent kinase 1
CFL1 cofilin 1 (non-muscle)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CLTC clathrin, heavy chain (Hc)
CLU clusterin
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB3 cAMP responsive element binding protein 3
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSB cathepsin B
CTSD cathepsin D
DARS aspartyl-tRNA synthetase
DCXR dicarbonyl/L-xylulose reductase
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DMWD dystrophia myotonica, WD repeat containing
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EEF1B2 eukaryotic translation elongation factor 1 beta 2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4A1 eukaryotic translation initiation factor 4A1
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
EPRS glutamyl-prolyl-tRNA synthetase
ERO1L ERO1-like (S. cerevisiae)
ERP29 endoplasmic reticulum protein 29
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM27E3 family with sequence similarity 27, member E3
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FLNA filamin A, alpha
FLNC filamin C, gamma
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
GALK1 galactokinase 1
GANAB glucosidase, alpha; neutral AB
GBAS glioblastoma amplified sequence
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GLB1 galactosidase, beta 1
GLUD1 glutamate dehydrogenase 1
GPRASP2 G protein-coupled receptor associated sorting protein 2
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GUSB glucuronidase, beta
H1FX H1 histone family, member X
H2AFX H2A histone family, member X
HAX1 HCLS1 associated protein X-1
HBB hemoglobin, beta
HEXA hexosaminidase A (alpha polypeptide)
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HIST1H1D histone cluster 1, H1d
HIST1H2BF histone cluster 1, H2bf
HIST1H4F histone cluster 1, H4f
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HNRNPCL1 heterogeneous nuclear ribonucleoprotein C-like 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1B heat shock 70kDa protein 1B
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HYOU1 hypoxia up-regulated 1
IARS isoleucyl-tRNA synthetase
ICAM1 intercellular adhesion molecule 1
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
IQGAP2 IQ motif containing GTPase activating protein 2
IRS4 insulin receptor substrate 4
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LDHB lactate dehydrogenase B
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMNA lamin A/C
LRPPRC leucine-rich pentatricopeptide repeat containing
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MATR3 matrin 3
MLF2 myeloid leukemia factor 2
MSI2 musashi RNA-binding protein 2
MSN moesin
NACA nascent polypeptide-associated complex alpha subunit
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NISCH nischarin
NONO non-POU domain containing, octamer-binding
NPEPPS aminopeptidase puromycin sensitive
NUCLEOLIN nucleolin multifunctional protein
NUP155 nucleoporin 155kDa
NUP93 nucleoporin 93kDa
OAT ornithine aminotransferase
P3H1 prolyl 3-hydroxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HB prolyl 4-hydroxylase, beta polypeptide
PABPC1 poly(A) binding protein, cytoplasmic 1
PARP1 poly (ADP-ribose) polymerase 1
PCBP2 poly(rC) binding protein 2
PCCA propionyl CoA carboxylase, alpha polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PDCD6 programmed cell death 6
PDIA4 protein disulfide isomerase family A, member 4
PDIA6 protein disulfide isomerase family A, member 6
PEF1 penta-EF-hand domain containing 1
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PKM pyruvate kinase, muscle
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POFUT1 protein O-fucosyltransferase 1
PON2 paraoxonase 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP5C protein phosphatase 5, catalytic subunit
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRDX6 peroxiredoxin 6
PRKCSH protein kinase C substrate 80K-H
PRPF8 pre-mRNA processing factor 8
PRRC2A proline-rich coiled-coil 2A
PSAP prosaposin
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTBP1 polypyrimidine tract binding protein 1
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
QARS glutaminyl-tRNA synthetase
RAB11B RAB11B, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RFC3 replication factor C (activator 1) 3, 38kDa
RMDN1 regulator of microtubule dynamics 1
RPL10 ribosomal protein L10
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL17 ribosomal protein L17
RPL18 ribosomal protein L18
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL24 ribosomal protein L24
RPL31 ribosomal protein L31
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPLP2 ribosomal protein, large, P2
RPN2 ribophorin II
RPS10 ribosomal protein S10
RPS13 ribosomal protein S13
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS2 ribosomal protein S2
RPS23 ribosomal protein S23
RPS3A ribosomal protein S3A
RPS6 ribosomal protein S6
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RSL1D1 ribosomal L1 domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCRIB scribbled planar cell polarity protein
SDF2 stromal cell-derived factor 2
SDF2L1 stromal cell-derived factor 2-like 1
SDF4 stromal cell derived factor 4
SEC13 SEC13 homolog (S. cerevisiae)
SEC16A SEC16 homolog A (S. cerevisiae)
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SF3B1 splicing factor 3b, subunit 1, 155kDa
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFPQ splicing factor proline/glutamine-rich
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SOD2 superoxide dismutase 2, mitochondrial
SRM spermidine synthase
SRSF1 serine/arginine-rich splicing factor 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SUMF2 sulfatase modifying factor 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAGLN2 transgelin 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TKT transketolase
TOR1A torsin family 1, member A (torsin A)
TOR1B torsin family 1, member B (torsin B)
TRAP1 TNF receptor-associated protein 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSNAX translin-associated factor X
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TUBB6 tubulin, beta 6 class V
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum)
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP12 ubiquitin specific peptidase 12
USP46 ubiquitin specific peptidase 46
USP9X ubiquitin specific peptidase 9, X-linked
VARS valyl-tRNA synthetase
VAT1 vesicle amine transport 1
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR48 WD repeat domain 48
WDR6 WD repeat domain 6
WDR77 WD repeat domain 77
XPOT exportin, tRNA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta