| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | prolyl 4-hydroxylase, beta polypeptide|This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5034) |
| External Link | https://ncbi.nlm.nih.gov/gene/5034 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the P4HB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI44L | interferon-induced protein 44-like | 0.0126495 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0123467 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0123035 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0107139 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0106382 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0103653 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.0100941 |
| CD320 | CD320 molecule | 0.0095791 |
| GLS | glutaminase | 0.00945324 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00943478 |
| NIBAN1 | niban apoptosis regulator 1 | 0.009379 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00927477 |
| MAGEA3 | melanoma antigen family A3 | 0.00918618 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00892197 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00887163 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00884898 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00882023 |
| MX1 | MX dynamin-like GTPase 1 | 0.0088077 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00875945 |
| MCOLN1 | mucolipin 1 | 0.00864567 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.0085866 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0085783 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.00834071 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00827451 |
| TXNIP | thioredoxin interacting protein | 0.00826373 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00822638 |
| ATP13A3 | ATPase type 13A3 | 0.00819986 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00812322 |
| CADM1 | cell adhesion molecule 1 | 0.00811402 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00809901 |
| CEP170 | centrosomal protein 170kDa | 0.00798212 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00797273 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00789162 |
| SMAD7 | SMAD family member 7 | 0.00782066 |
| KIF5B | kinesin family member 5B | 0.00779104 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00778833 |
| MAP1B | microtubule-associated protein 1B | 0.0077157 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00771405 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00767737 |
| PDGFC | platelet derived growth factor C | 0.00767736 |
| ZIC1 | Zic family member 1 | 0.00759429 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00751357 |
| ZNF148 | zinc finger protein 148 | 0.00749558 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00748818 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.00746849 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.00745957 |
| KMT5B | lysine methyltransferase 5B | 0.00745404 |
| HAT1 | histone acetyltransferase 1 | 0.00745148 |
| NFIB | nuclear factor I/B | 0.00742559 |
| POSTN | periostin, osteoblast specific factor | 0.00740078 |
| IL7R | interleukin 7 receptor | 0.00739557 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00739466 |
| TMEM106B | transmembrane protein 106B | 0.00739109 |
| NOTCH2 | notch 2 | 0.00738636 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00737805 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00736406 |
| TYMP | thymidine phosphorylase | 0.00728042 |
| ITM2A | integral membrane protein 2A | 0.00725924 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00719046 |
| CFB | complement factor B | 0.00718458 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00714265 |
| TLE2 | transducin-like enhancer of split 2 | 0.00713476 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00712767 |
| CD2 | CD2 molecule | 0.00712647 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00712387 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00709979 |
| PCP4 | Purkinje cell protein 4 | 0.00706965 |
| IFI44 | interferon-induced protein 44 | 0.0070602 |
| XAF1 | XIAP associated factor 1 | 0.00703188 |
| FOLR1 | folate receptor 1 (adult) | 0.00702851 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00702693 |
| MAML1 | mastermind-like 1 (Drosophila) | 0.00700659 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.00696083 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00691776 |
| HCP5 | HLA complex P5 (non-protein coding) | 0.00684231 |
| IRF9 | interferon regulatory factor 9 | 0.00680403 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.006799 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 0.00678664 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00676227 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00674543 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00673567 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00667452 |
| WT1 | Wilms tumor 1 | 0.00661642 |
| SYNM | synemin, intermediate filament protein | 0.00657412 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00655256 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00650823 |
| ZNF91 | zinc finger protein 91 | 0.00650361 |
| CTPS1 | CTP synthase 1 | 0.00649946 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00649768 |
| SFTPB | surfactant protein B | 0.00645405 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.00645196 |
| ADNP | activity-dependent neuroprotector homeobox | 0.00645042 |
| NCKAP1 | NCK-associated protein 1 | 0.00644191 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00643347 |
| C4BPA | complement component 4 binding protein, alpha | 0.00642908 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00642834 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00642361 |
| TGOLN2 | trans-golgi network protein 2 | 0.00637051 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00636557 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00636348 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00635548 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0063491 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.00634556 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00631904 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.00630707 |
| CDK19 | cyclin-dependent kinase 19 | 0.00630587 |
| SACS | sacsin molecular chaperone | 0.0062995 |
| USP1 | ubiquitin specific peptidase 1 | 0.00629545 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.00629335 |
| RAP2A | RAP2A, member of RAS oncogene family | 0.00628608 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.00628359 |
| NCOA2 | nuclear receptor coactivator 2 | 0.00626983 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.00626318 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.0062523 |
| AZF1 | azoospermia factor 1 | 0.00624655 |
| BCL7B | B-cell CLL/lymphoma 7B | 0.00624366 |
| GOLIM4 | golgi integral membrane protein 4 | 0.00622815 |
| NUP133 | nucleoporin 133kDa | 0.00620041 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00619506 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.00616092 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.00615521 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.0061507 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00614362 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00611958 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.00611049 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | 0.0061102 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00609367 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00609318 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00609189 |
| TOR1AIP1 | torsin A interacting protein 1 | 0.00608342 |
| PCDH9 | protocadherin 9 | 0.00607864 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.00607863 |
| RBM15 | RNA binding motif protein 15 | 0.00606909 |
| SOCS5 | suppressor of cytokine signaling 5 | 0.00605158 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0060505 |
| PTN | pleiotrophin | 0.00604455 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00604043 |
| ZMPSTE24 | zinc metallopeptidase STE24 | 0.00602373 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00600822 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00600652 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.00600383 |
| STK25 | serine/threonine kinase 25 | 0.00599954 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00598235 |
| CDK17 | cyclin-dependent kinase 17 | 0.00597742 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00597341 |
| IPO5 | importin 5 | 0.00596181 |
| HSPA14 | heat shock 70kDa protein 14 | 0.00594466 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00593786 |
| METTL7A | methyltransferase like 7A | 0.00592771 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00592223 |
| DCLK1 | doublecortin-like kinase 1 | 0.00591908 |
| CPM | carboxypeptidase M | 0.00590015 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0058853 |
| STAG2 | stromal antigen 2 | 0.00587495 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00586832 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00586743 |
| KLHL23 | kelch-like family member 23 | 0.00585655 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00585446 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00585435 |
| S100A2 | S100 calcium binding protein A2 | 0.00584051 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00583756 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00583638 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00581736 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00580792 |
| INSIG1 | insulin induced gene 1 | 0.00579846 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00579416 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00577999 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 0.00576271 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.00576018 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00575467 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00575333 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00574617 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00574125 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.00573262 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00571857 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00570868 |
| USP47 | ubiquitin specific peptidase 47 | 0.00570662 |
| TCERG1 | transcription elongation regulator 1 | 0.00569701 |
| TMEM109 | transmembrane protein 109 | 0.00569537 |
| TUT7 | terminal uridylyl transferase 7 | 0.0056946 |
| LUM | lumican | 0.00568698 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00568086 |
| TTC37 | tetratricopeptide repeat domain 37 | 0.00565697 |
| TLR4 | toll-like receptor 4 | 0.00565374 |
| PRF1 | perforin 1 (pore forming protein) | 0.00564663 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.00562992 |
| SMC2 | structural maintenance of chromosomes 2 | 0.00562777 |
| MPDZ | multiple PDZ domain protein | 0.00562498 |
| CREB1 | cAMP responsive element binding protein 1 | 0.00561935 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.00560972 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00560172 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00560096 |
| TRIM22 | tripartite motif containing 22 | 0.00559591 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.0055661 |
| ATMIN | ATM interactor | 0.00556241 |
| IPO9 | importin 9 | 0.00555441 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0055359 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.00553296 |
| FAAH | fatty acid amide hydrolase | 0.00553066 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00553 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.00552849 |
| IL2RB | interleukin 2 receptor, beta | 0.00552648 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.00552511 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | 0.00551243 |
| BCHE | butyrylcholinesterase | 0.00550107 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.00549617 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00544953 |
| CD151 | CD151 molecule (Raph blood group) | 0.00544344 |
| STK26 | serine/threonine protein kinase 26 | 0.00542874 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0054176 |
| TSFM | Ts translation elongation factor, mitochondrial | 0.00541445 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.00541298 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00539671 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 | 0.00539452 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00539393 |
| NAV2 | neuron navigator 2 | 0.00538864 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00538756 |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) | 0.00537981 |
| MFGE8 | milk fat globule-EGF factor 8 protein | 0.00537749 |
| MAGEA12 | melanoma antigen family A12 | 0.00537712 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00535424 |
| WWC3 | WWC family member 3 | 0.00535137 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.00534465 |
| LBH | limb bud and heart development | 0.00534323 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.00533258 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00532384 |
| SOCS3 | suppressor of cytokine signaling 3 | 0.00531875 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.00531354 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00530975 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00530401 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00530188 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.00529871 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00529456 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.00529002 |
| GLRX2 | glutaredoxin 2 | 0.00528328 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00527187 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.0052708 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00525238 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00524013 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.00523278 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.00523034 |
| DVL1 | dishevelled segment polarity protein 1 | 0.00522448 |
| FBLN1 | fibulin 1 | 0.00521432 |
| SCG5 | secretogranin V | 0.00520684 |
| AIFM1 | apoptosis-inducing factor, mitochondrion-associated, 1 | 0.00520617 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | 0.00520035 |
| RNF144A | ring finger protein 144A | 0.00519794 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00519785 |
| ELN | elastin | 0.00519758 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | -0.0173545 |
| RGCC | regulator of cell cycle | -0.0155485 |
| KRT19 | keratin 19, type I | -0.014172 |
| CDC42 | cell division cycle 42 | -0.014004 |
| S100A10 | S100 calcium binding protein A10 | -0.0138884 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0135701 |
| CSTA | cystatin A (stefin A) | -0.013118 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0126835 |
| PEG3 | paternally expressed 3 | -0.0125604 |
| XIC | X chromosome inactivation center | -0.0124812 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | -0.0124097 |
| RAB25 | RAB25, member RAS oncogene family | -0.0120323 |
| GRB7 | growth factor receptor-bound protein 7 | -0.011682 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.0111784 |
| GUCY2C | guanylate cyclase 2C | -0.0111064 |
| YBX3 | Y box binding protein 3 | -0.0109479 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0108088 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.010734 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.01051 |
| SMAD3 | SMAD family member 3 | -0.0104785 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0104768 |
| S100P | S100 calcium binding protein P | -0.0103897 |
| FN1 | fibronectin 1 | -0.0103602 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0103292 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0102297 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0101428 |
| CLEC11A | C-type lectin domain family 11, member A | -0.0101359 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0101078 |
| S100A14 | S100 calcium binding protein A14 | -0.0100347 |
| CLDN7 | claudin 7 | -0.00992455 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00985768 |
| PITX1 | paired-like homeodomain 1 | -0.00982756 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00980102 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.009699 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00969145 |
| KLK10 | kallikrein-related peptidase 10 | -0.00966173 |
| AHCY | adenosylhomocysteinase | -0.00963803 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.0095794 |
| SST | somatostatin | -0.00954878 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00951272 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.00949768 |
| ANXA6 | annexin A6 | -0.0093622 |
| H1-10 | H1.10 linker histone | -0.00932878 |
| AHNAK | AHNAK nucleoprotein | -0.00931167 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00930177 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00928126 |
| BAX | BCL2-associated X protein | -0.00906553 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.00897379 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00894883 |
| DEFB1 | defensin, beta 1 | -0.00893047 |
| HMGA1 | high mobility group AT-hook 1 | -0.0088935 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00887103 |
| S100A7 | S100 calcium binding protein A7 | -0.0088286 |
| GSTZ1 | glutathione S-transferase zeta 1 | -0.00880699 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00880468 |
| PLIN3 | perilipin 3 | -0.00877743 |
| PLLP | plasmolipin | -0.0087107 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00870699 |
| ADM | adrenomedullin | -0.00867879 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00867569 |
| ANXA2 | annexin A2 | -0.00863071 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00860828 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -0.00858145 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00856138 |
| CLDN10 | claudin 10 | -0.00853943 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00850004 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00847629 |
| RPL14 | ribosomal protein L14 | -0.00845059 |
| AGR2 | anterior gradient 2 | -0.00835625 |
| INAVA | innate immunity activator | -0.0082855 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00819527 |
| FLNA | filamin A, alpha | -0.00818956 |
| CFD | complement factor D (adipsin) | -0.00816474 |
| FERMT1 | fermitin family member 1 | -0.00813274 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -0.00812042 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | -0.00805998 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00804805 |
| CST1 | cystatin SN | -0.00803327 |
| KRT13 | keratin 13, type I | -0.00798448 |
| PYCARD | PYD and CARD domain containing | -0.00796702 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00787308 |
| ADIRF | adipogenesis regulatory factor | -0.00785905 |
| PXDN | peroxidasin | -0.00779277 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00775187 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00774015 |
| HTRA1 | HtrA serine peptidase 1 | -0.00771507 |
| CLDN8 | claudin 8 | -0.00768945 |
| ATF4 | activating transcription factor 4 | -0.00768664 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00765591 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00765573 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00758482 |
| ELANE | elastase, neutrophil expressed | -0.00757049 |
| OLFML3 | olfactomedin-like 3 | -0.0075222 |
| THBS1 | thrombospondin 1 | -0.00751337 |
| ITM2C | integral membrane protein 2C | -0.0075068 |
| KLF6 | Kruppel-like factor 6 | -0.00749246 |
| ABLIM1 | actin binding LIM protein 1 | -0.00748622 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00744808 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00743684 |
| EPCAM | epithelial cell adhesion molecule | -0.0074167 |
| COPS7A | COP9 signalosome subunit 7A | -0.00740994 |
| GPX2 | glutathione peroxidase 2 | -0.00737933 |
| CST6 | cystatin E/M | -0.00735121 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.0073349 |
| WDR61 | WD repeat domain 61 | -0.00733331 |
| PLK1 | polo-like kinase 1 | -0.00729968 |
| FA2H | fatty acid 2-hydroxylase | -0.00729396 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0072401 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00722496 |
| ATF3 | activating transcription factor 3 | -0.0071845 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.00715705 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.00715291 |
| EZR | ezrin | -0.00712919 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00711446 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00710297 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00709752 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00709381 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00706254 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00706189 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00705585 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00698624 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00695821 |
| HOXB7 | homeobox B7 | -0.0069513 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00687058 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00686852 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00686827 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -0.00686782 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00682931 |
| GSDMB | gasdermin B | -0.00679773 |
| IRF8 | interferon regulatory factor 8 | -0.00677992 |
| CD9 | CD9 molecule | -0.00673679 |
| APH1A | APH1A gamma secretase subunit | -0.00672162 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00671768 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00670063 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) | -0.00668599 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.00666309 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00665736 |
| HEBP2 | heme binding protein 2 | -0.00665679 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.00664837 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0066474 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00664724 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00660658 |
| IL10RB | interleukin 10 receptor, beta | -0.00660191 |
| LCN2 | lipocalin 2 | -0.006601 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00657488 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00657009 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | -0.00655918 |
| HOXC6 | homeobox C6 | -0.00652767 |
| KLK8 | kallikrein-related peptidase 8 | -0.00652752 |
| RAB5C | RAB5C, member RAS oncogene family | -0.006481 |
| RPS9 | ribosomal protein S9 | -0.00647228 |
| RHOA | ras homolog family member A | -0.00647208 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00645299 |
| GDF15 | growth differentiation factor 15 | -0.00645254 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00642842 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00642613 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00642122 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00641182 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | -0.00640772 |
| RIMBP2 | RIMS binding protein 2 | -0.00638175 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00636469 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00634253 |
| KRT23 | keratin 23, type I | -0.00633653 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00631968 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.0062966 |
| NEBL | nebulette | -0.00629284 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00628352 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00627754 |
| MYRF | myelin regulatory factor | -0.00627609 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00626441 |
| GRAMD1C | GRAM domain containing 1C | -0.00626161 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | -0.00623961 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00623114 |
| C6ORF48 | chromosome 6 open reading frame 48 | -0.00621322 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00620219 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00619187 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00618778 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | -0.00617001 |
| CALML5 | calmodulin-like 5 | -0.00616298 |
| H1-2 | H1.2 linker histone, cluster member | -0.0061552 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00614828 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00613448 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -0.00612511 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00611704 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00611325 |
| MPO | myeloperoxidase | -0.00609449 |
| AMZ2 | archaelysin family metallopeptidase 2 | -0.0060878 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00607253 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | -0.00606232 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00606108 |
| FLNB | filamin B, beta | -0.00604695 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | -0.00604266 |
| C21ORF33 | chromosome 21 open reading frame 33 | -0.00604215 |
| ARSL | arylsulfatase L | -0.00603464 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00601401 |
| ASRGL1 | asparaginase like 1 | -0.00601172 |
| SET | SET nuclear proto-oncogene | -0.0060069 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.00600551 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.00597537 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00597222 |
| LOXL2 | lysyl oxidase-like 2 | -0.00595937 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00595039 |
| TSPAN8 | tetraspanin 8 | -0.00593757 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0059349 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.005933 |
| SMAGP | small cell adhesion glycoprotein | -0.00593229 |
| PRPF4 | pre-mRNA processing factor 4 | -0.00592968 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00591606 |
| LTA4H | leukotriene A4 hydrolase | -0.00591035 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00590537 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.00590368 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.00588764 |
| COLEC11 | collectin sub-family member 11 | -0.00588639 |
| CD200 | CD200 molecule | -0.00587012 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00586304 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00585201 |
| SNCAIP | synuclein, alpha interacting protein | -0.00584214 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | -0.00582247 |
| EDN3 | endothelin 3 | -0.00582138 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | -0.00580415 |
| COG7 | component of oligomeric golgi complex 7 | -0.0058027 |
| EMX2 | empty spiracles homeobox 2 | -0.00579174 |
| LASP1 | LIM and SH3 protein 1 | -0.00579119 |
| EPS8L1 | EPS8-like 1 | -0.0057902 |
| LIAS | lipoic acid synthetase | -0.00578887 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00578223 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0057707 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00575684 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00575547 |
| C1ORF54 | chromosome 1 open reading frame 54 | -0.00574586 |
| SDC1 | syndecan 1 | -0.0057397 |
| RHOC | ras homolog family member C | -0.00572961 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0057281 |
| MME | membrane metallo-endopeptidase | -0.0057262 |
| NOTCH1 | notch 1 | -0.00572404 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00571333 |
| ERVMER34-1 | endogenous retrovirus group MER34, member 1 | -0.00570685 |
| MAOB | monoamine oxidase B | -0.00570359 |
| NPTX2 | neuronal pentraxin II | -0.00568344 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -0.00567676 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00566811 |
| PRKCA | protein kinase C, alpha | -0.00566178 |
| CYB561 | cytochrome b561 | -0.00565984 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00565555 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.00565352 |
| TPM2 | tropomyosin 2 (beta) | -0.00565247 |
| CLCA4 | chloride channel accessory 4 | -0.00565048 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | -0.00564596 |
| TAGLN2 | transgelin 2 | -0.00564131 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -0.00563115 |
