PA-1 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human ovary ascites teratocarcinoma cell line. The line was established from cells taken from ascitic fluid. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001591)
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Genes

397 genes mutated in the PA-1 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACAD10 acyl-CoA dehydrogenase family, member 10
ACBD5 acyl-CoA binding domain containing 5
ACTG1 actin gamma 1
ACVR2A activin A receptor, type IIA
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAMTSL2 ADAMTS-like 2
ADCK1 aarF domain containing kinase 1
ADCY10 adenylate cyclase 10 (soluble)
ADGRE2 adhesion G protein-coupled receptor E2
AFTPH aftiphilin
AHCTF1 AT hook containing transcription factor 1
AKR1E2 aldo-keto reductase family 1, member E2
ALG8 ALG8, alpha-1,3-glucosyltransferase
AMD1 adenosylmethionine decarboxylase 1
ANKHD1 ankyrin repeat and KH domain containing 1
ANKHD1-EIF4EBP3 ANKHD1-EIF4EBP3 readthrough
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD36C ankyrin repeat domain 36C
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APH1B APH1B gamma secretase subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASF1A anti-silencing function 1A histone chaperone
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
AVPR2 arginine vasopressin receptor 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BEST3 bestrophin 3
BROX BRO1 domain and CAAX motif containing
BTG3 BTG family, member 3
CA4 carbonic anhydrase IV
CACFD1 calcium channel flower domain containing 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALR3 calreticulin 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCDC89 coiled-coil domain containing 89
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD180 CD180 molecule
CDH16 cadherin 16, KSP-cadherin
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKL4 cyclin-dependent kinase-like 4
CENPE centromere protein E, 312kDa
CEP162 centrosomal protein 162kDa
CEP68 centrosomal protein 68kDa
CERKL ceramide kinase-like
CFAP58 cilia and flagella associated protein 58
CFAP97 cilia and flagella associated protein 97
CGNL1 cingulin-like 1
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5
CHD7 chromodomain helicase DNA binding protein 7
CHRND cholinergic receptor, nicotinic, delta (muscle)
CLEC1B C-type lectin domain family 1, member B
CLSTN1 calsyntenin 1
CLUH clustered mitochondria (cluA/CLU1) homolog
COL24A1 collagen, type XXIV, alpha 1
COL25A1 collagen, type XXV, alpha 1
COL27A1 collagen, type XXVII, alpha 1
COL6A1 collagen, type VI, alpha 1
CPZ carboxypeptidase Z
CREBBP CREB binding protein
CSRNP2 cysteine-serine-rich nuclear protein 2
CT45A5 cancer/testis antigen family 45, member A5
CTC1 CTS telomere maintenance complex component 1
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL16 chemokine (C-X-C motif) ligand 16
CXXC4 CXXC finger protein 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND5B DENN/MADD domain containing 5B
DERL1 derlin 1
DGKB diacylglycerol kinase, beta 90kDa
DIDO1 death inducer-obliterator 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DMXL2 Dmx-like 2
DNAL1 dynein, axonemal, light chain 1
DTX3 deltex 3, E3 ubiquitin ligase
DUSP28 dual specificity phosphatase 28
DZIP3 DAZ interacting zinc finger protein 3
EFR3A EFR3 homolog A (S. cerevisiae)
EHBP1L1 EH domain binding protein 1-like 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EML1 echinoderm microtubule associated protein like 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EP400 E1A binding protein p400
EPB42 erythrocyte membrane protein band 4.2
EPPK1 epiplakin 1
ERCC6L2 excision repair cross-complementation group 6-like 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETFDH electron-transferring-flavoprotein dehydrogenase
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
FAM105A family with sequence similarity 105, member A
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM134B family with sequence similarity 134, member B
FAM193A family with sequence similarity 193, member A
FAM196B family with sequence similarity 196, member B
FAM9A family with sequence similarity 9, member A
FANCA Fanconi anemia, complementation group A
FANCD2 Fanconi anemia, complementation group D2
FASTK Fas-activated serine/threonine kinase
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FLNA filamin A, alpha
FRMPD1 FERM and PDZ domain containing 1
GAA glucosidase, alpha; acid
GAB4 GRB2-associated binding protein family, member 4
GALC galactosylceramidase
GAS2L3 growth arrest-specific 2 like 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBA glucosidase, beta, acid
GDF9 growth differentiation factor 9
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GHITM growth hormone inducible transmembrane protein
GJB1 gap junction protein, beta 1, 32kDa
GLTSCR1L GLTSCR1-like
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GOLGA6C golgin A6 family, member C
GP2 glycoprotein 2 (zymogen granule membrane)
GREB1 growth regulation by estrogen in breast cancer 1
GRM7 glutamate receptor, metabotropic 7
GRM8 glutamate receptor, metabotropic 8
GTSE1 G-2 and S-phase expressed 1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HK3 hexokinase 3 (white cell)
HKDC1 hexokinase domain containing 1
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGXB3 HMG box domain containing 3
HOXC5 homeobox C5
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSF2 heat shock transcription factor 2
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic
HTT huntingtin
HUS1 HUS1 checkpoint homolog (S. pombe)
IFITM1 interferon induced transmembrane protein 1
IFNE interferon, epsilon
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL5RA interleukin 5 receptor, alpha
IL6ST interleukin 6 signal transducer
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
ING1 inhibitor of growth family, member 1
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IQCF3 IQ motif containing F3
IQUB IQ motif and ubiquitin domain containing
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
JARID2 jumonji, AT rich interactive domain 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCTD16 potassium channel tetramerization domain containing 16
KDM5C lysine (K)-specific demethylase 5C
KIAA1456 KIAA1456
KIAA1614 KIAA1614
KIAA1671 KIAA1671
KLHL24 kelch-like family member 24
KLHL36 kelch-like family member 36
KMT2D lysine (K)-specific methyltransferase 2D
KRT7 keratin 7, type II
LEPR leptin receptor
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LGSN lengsin, lens protein with glutamine synthetase domain
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LIM2 lens intrinsic membrane protein 2, 19kDa
LINGO4 leucine rich repeat and Ig domain containing 4
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRP2 low density lipoprotein receptor-related protein 2
LRRC34 leucine rich repeat containing 34
LRRIQ1 leucine-rich repeats and IQ motif containing 1
LRRK2 leucine-rich repeat kinase 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
MAGEE1 melanoma antigen family E1
MAMDC2 MAM domain containing 2
MAP1B microtubule-associated protein 1B
MAP2K2 mitogen-activated protein kinase kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MED23 mediator complex subunit 23
METAP2 methionyl aminopeptidase 2
MFN2 mitofusin 2
MFSD1 major facilitator superfamily domain containing 1
MIA3 melanoma inhibitory activity family, member 3
MKL1 megakaryoblastic leukemia (translocation) 1
MSI1 musashi RNA-binding protein 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MTTP microsomal triglyceride transfer protein
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH9 myosin, heavy chain 9, non-muscle
MYLK myosin light chain kinase
MYO5A myosin VA (heavy chain 12, myoxin)
MYO6 myosin VI
NBPF10 neuroblastoma breakpoint family, member 10
NCKAP5L NCK-associated protein 5-like
NCS1 neuronal calcium sensor 1
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NEK1 NIMA-related kinase 1
NELL1 NEL-like 1 (chicken)
NEO1 neogenin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NINL ninein-like
NKD2 naked cuticle homolog 2 (Drosophila)
NLGN4X neuroligin 4, X-linked
NOAZFP nucleolar atypical zinc finger
NOD1 nucleotide-binding oligomerization domain containing 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPY4R neuropeptide Y receptor Y4
NRAP nebulin-related anchoring protein
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTNG2 netrin G2
NUCLEOLIN nucleolin multifunctional protein
NUP93 nucleoporin 93kDa
NWD1 NACHT and WD repeat domain containing 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OFCC1 orofacial cleft 1 candidate 1
OFD1 oral-facial-digital syndrome 1
OPRM1 opioid receptor, mu 1
OR10A7 olfactory receptor, family 10, subfamily A, member 7
OR13A1 olfactory receptor, family 13, subfamily A, member 1
OR51I1 olfactory receptor, family 51, subfamily I, member 1
OR5H15 olfactory receptor, family 5, subfamily H, member 15
OR5P2 olfactory receptor, family 5, subfamily P, member 2
OTOG otogelin
PAH phenylalanine hydroxylase
PARD6B par-6 family cell polarity regulator beta
PCDHB7 protocadherin beta 7
PCLO piccolo presynaptic cytomatrix protein
PCNXL2 pecanex-like 2 (Drosophila)
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDE7B phosphodiesterase 7B
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PEG3 paternally expressed 3
PGM5 phosphoglucomutase 5
PGR progesterone receptor
PHC1P1 polyhomeotic homolog 1 (Drosophila) pseudogene 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKDREJ polycystin (PKD) family receptor for egg jelly
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLBD1 phospholipase B domain containing 1
PLBD2 phospholipase B domain containing 2
PLEK2 pleckstrin 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLXNB3 plexin B3
POC1B POC1 centriolar protein B
PODN podocan
POM121L4P POM121 transmembrane nucleoporin-like 4 pseudogene
POTEI POTE ankyrin domain family, member I
PPARA peroxisome proliferator-activated receptor alpha
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PQLC2 PQ loop repeat containing 2
PREP prolyl endopeptidase
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB20 RAB20, member RAS oncogene family
RAB34 RAB34, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAI1 retinoic acid induced 1
RANBP6 RAN binding protein 6
RASD2 RASD family, member 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASIP1 Ras interacting protein 1
RBM15B RNA binding motif protein 15B
RBMXL3 RNA binding motif protein, X-linked-like 3
RHOT2 ras homolog family member T2
RIC1 RAB6A GEF complex partner 1
RIF1 replication timing regulatory factor 1
RND3 Rho family GTPase 3
RNF123 ring finger protein 123
RNF185 ring finger protein 185
RSPH3 radial spoke 3 homolog (Chlamydomonas)
RXFP2 relaxin/insulin-like family peptide receptor 2
RYR1 ryanodine receptor 1 (skeletal)
SALL3 spalt-like transcription factor 3
SCML1 sex comb on midleg-like 1 (Drosophila)
SCN7A sodium channel, voltage gated, type VII alpha subunit
SEC16A SEC16 homolog A (S. cerevisiae)
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SETBP1 SET binding protein 1
SEZ6 seizure related 6 homolog (mouse)
SGSM2 small G protein signaling modulator 2
SIGLEC9 sialic acid binding Ig-like lectin 9
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A45 solute carrier family 25, member 45
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC38A9 solute carrier family 38, member 9
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SNCAIP synuclein, alpha interacting protein
SNX6 sorting nexin 6
SNX8 sorting nexin 8
SORCS2 sortilin-related VPS10 domain containing receptor 2
SORCS3 sortilin-related VPS10 domain containing receptor 3
SP5 Sp5 transcription factor
SPATA20 spermatogenesis associated 20
SPATA3 spermatogenesis associated 3
SQLE squalene epoxidase
SRPRB signal recognition particle receptor, B subunit
STK26 serine/threonine protein kinase 26
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNPO2 synaptopodin 2
SYP synaptophysin
TAGAP T-cell activation RhoGTPase activating protein
TAS2R31 taste receptor, type 2, member 31
TBC1D2B TBC1 domain family, member 2B
TBCCD1 TBCC domain containing 1
TBL2 transducin (beta)-like 2
TBRG4 transforming growth factor beta regulator 4
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCF25 transcription factor 25 (basic helix-loop-helix)
TCP11 t-complex 11, testis-specific
TEKT5 tektin 5
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TINAG tubulointerstitial nephritis antigen
TLR6 toll-like receptor 6
TMCO2 transmembrane and coiled-coil domains 2
TMEM132C transmembrane protein 132C
TMEM156 transmembrane protein 156
TMEM57 transmembrane protein 57
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TPST1 tyrosylprotein sulfotransferase 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM64C tripartite motif containing 64C
TRIP11 thyroid hormone receptor interactor 11
TSLIG3C tRNA splicing ligase complex subunit 3C
TTLL3 tubulin tyrosine ligase-like family member 3
TTN titin
TULP1 tubby like protein 1
TWF2 twinfilin actin binding protein 2
UBN1 ubinuclein 1
UFD1L ubiquitin fusion degradation 1 like (yeast)
USHBP1 Usher syndrome 1C binding protein 1
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
VCAN versican
VIM vimentin
VWA8 von Willebrand factor A domain containing 8
WBSCR27 Williams Beuren syndrome chromosome region 27
WDR7 WD repeat domain 7
WDR93 WD repeat domain 93
WNK3 WNK lysine deficient protein kinase 3
WNT2 wingless-type MMTV integration site family member 2
WNT7A wingless-type MMTV integration site family, member 7A
WSB2 WD repeat and SOCS box containing 2
XAF1 XIAP associated factor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZC3H11A zinc finger CCCH-type containing 11A
ZC3H14 zinc finger CCCH-type containing 14
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZCCHC14 zinc finger, CCHC domain containing 14
ZDHHC23 zinc finger, DHHC-type containing 23
ZER1 zyg-11 related, cell cycle regulator
ZFYVE28 zinc finger, FYVE domain containing 28
ZHX3 zinc fingers and homeoboxes 3
ZIM2 zinc finger, imprinted 2
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF177 zinc finger protein 177
ZNF185 zinc finger protein 185 (LIM domain)
ZNF239 zinc finger protein 239
ZNF253 zinc finger protein 253
ZNF257 zinc finger protein 257
ZNF28 zinc finger protein 28
ZNF292 zinc finger protein 292
ZNF358 zinc finger protein 358
ZNF43 zinc finger protein 43
ZNF486 zinc finger protein 486
ZNF627 zinc finger protein 627
ZNF714 zinc finger protein 714
ZNF729 zinc finger protein 729
ZNF747 zinc finger protein 747
ZNF836 zinc finger protein 836
ZNF878 zinc finger protein 878
ZUFSP zinc finger with UFM1-specific peptidase domain