PADI4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description peptidyl arginine deiminase, type IV|This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 23569)
External Link https://ncbi.nlm.nih.gov/gene/23569
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Genes

500 genes differentially expressed following the PADI4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A 0.029596
TOX thymocyte selection-associated high mobility group box 0.0133537
MSLN mesothelin 0.0130442
SDC1 syndecan 1 0.0127871
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.0125002
INAVA innate immunity activator 0.0124362
ACTN1 actinin, alpha 1 0.0124204
PNMA2 paraneoplastic Ma antigen 2 0.0124174
XPO7 exportin 7 0.012267
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.0121835
C1R complement component 1, r subcomponent 0.0117784
BHLHE41 basic helix-loop-helix family, member e41 0.0115342
CLEC11A C-type lectin domain family 11, member A 0.0114694
FGFR3 fibroblast growth factor receptor 3 0.0114237
AQP3 aquaporin 3 (Gill blood group) 0.0113125
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0113079
GNAS GNAS complex locus 0.0111779
ABHD4 abhydrolase domain containing 4 0.011163
GAS1 growth arrest-specific 1 0.0111613
CA2 carbonic anhydrase II 0.0111007
CXCL12 chemokine (C-X-C motif) ligand 12 0.0107505
AUTS2 autism susceptibility candidate 2 0.0104076
S100A8 S100 calcium binding protein A8 0.0103398
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0102529
INSR insulin receptor 0.0102289
ASPN asporin 0.0102084
PUF60 poly-U binding splicing factor 60KDa 0.0101161
TNS3 tensin 3 0.0100059
CRABP2 cellular retinoic acid binding protein 2 0.00999662
CXCL14 chemokine (C-X-C motif) ligand 14 0.00988877
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.00986538
MXRA5 matrix-remodelling associated 5 0.00985817
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00981694
BMP2 bone morphogenetic protein 2 0.00974492
ITGB4 integrin, beta 4 0.00965668
PRKCA protein kinase C, alpha 0.00956127
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00942245
CD81 CD81 molecule 0.00941923
PXDN peroxidasin 0.00940596
CLIC5 chloride intracellular channel 5 0.00920248
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00911376
CDC20 cell division cycle 20 0.00910021
CYCS cytochrome c, somatic 0.0090879
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00905542
UNG uracil-DNA glycosylase 0.00904496
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00894283
TSPAN8 tetraspanin 8 0.00882253
GSPT2 G1 to S phase transition 2 0.00881802
NDRG1 N-myc downstream regulated 1 0.00879811
TRIM14 tripartite motif containing 14 0.00878688
TLE4 transducin-like enhancer of split 4 0.00870559
LY6E lymphocyte antigen 6 complex, locus E 0.00867626
FERMT1 fermitin family member 1 0.00865781
RAD23A RAD23 homolog A (S. cerevisiae) 0.00860357
ADIRF adipogenesis regulatory factor 0.00850111
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00849487
IFITM1 interferon induced transmembrane protein 1 0.00848665
C1S complement component 1, s subcomponent 0.00845201
MFAP5 microfibrillar associated protein 5 0.00844649
LGALS13 lectin, galactoside-binding, soluble, 13 0.00838122
TRIM29 tripartite motif containing 29 0.00834417
MGLL monoglyceride lipase 0.00833046
FSTL1 follistatin-like 1 0.00830221
RBM34 RNA binding motif protein 34 0.00825695
HOPX HOP homeobox 0.00825086
UBE2S ubiquitin-conjugating enzyme E2S 0.00824947
TMEM45A transmembrane protein 45A 0.00821924
SCRIB scribbled planar cell polarity protein 0.00821167
KLF5 Kruppel-like factor 5 (intestinal) 0.00817098
ITM2C integral membrane protein 2C 0.00811172
PDLIM2 PDZ and LIM domain 2 (mystique) 0.00808627
DTX4 deltex 4, E3 ubiquitin ligase 0.0080635
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00799828
SLPI secretory leukocyte peptidase inhibitor 0.00799285
ADGRG2 adhesion G protein-coupled receptor G2 0.00797415
OLFM4 olfactomedin 4 0.00797333
NFASC neurofascin 0.00793962
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00792476
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00791462
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00790548
THY1 Thy-1 cell surface antigen 0.00787991
ACTN4 actinin, alpha 4 0.00787612
HEPH hephaestin 0.00787398
CRYBG1 crystallin beta-gamma domain containing 1 0.00786034
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.0078233
C7 complement component 7 0.00781809
PRODH proline dehydrogenase (oxidase) 1 0.00779454
LOXL1 lysyl oxidase-like 1 0.00778014
FGFBP1 fibroblast growth factor binding protein 1 0.00775656
NAP1L3 nucleosome assembly protein 1-like 3 0.00770048
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00768426
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00766624
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00766025
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.00764123
DPYSL2 dihydropyrimidinase-like 2 0.00757299
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00756445
ARHGAP32 Rho GTPase activating protein 32 0.00756282
TYRP1 tyrosinase-related protein 1 0.00755341
L1TD1 LINE-1 type transposase domain containing 1 0.00747604
GSTP1 glutathione S-transferase pi 1 0.00740012
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.00737554
PRKD3 protein kinase D3 0.00735839
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00733483
EMX2 empty spiracles homeobox 2 0.00731162
CHRDL1 chordin-like 1 0.00730382
ABLIM1 actin binding LIM protein 1 0.00729878
MOXD1 monooxygenase, DBH-like 1 0.0072922
DUSP7 dual specificity phosphatase 7 0.00728721
RFC2 replication factor C (activator 1) 2, 40kDa 0.00727586
COL11A1 collagen, type XI, alpha 1 0.00725361
SRSF1 serine/arginine-rich splicing factor 1 0.00722388
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.00720601
LOXL2 lysyl oxidase-like 2 0.00719648
FNBP1 formin binding protein 1 0.00716868
ADAR adenosine deaminase, RNA-specific 0.00716462
ANKRD11 ankyrin repeat domain 11 0.00715602
PRUNE2 prune homolog 2 (Drosophila) 0.0071444
MCM2 minichromosome maintenance complex component 2 0.00709302
ELANE elastase, neutrophil expressed 0.00708726
MEN1 multiple endocrine neoplasia I 0.00708446
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00708345
VCL vinculin 0.00706596
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 0.00705632
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.0070494
PTBP1 polypyrimidine tract binding protein 1 0.00700935
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00699361
FSCN1 fascin actin-bundling protein 1 0.00698403
LIG1 ligase I, DNA, ATP-dependent 0.00696217
TMBIM6 transmembrane BAX inhibitor motif containing 6 0.00695222
SRSF5 serine/arginine-rich splicing factor 5 0.00693744
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00692589
MTA1 metastasis associated 1 0.00692072
IGFBP6 insulin-like growth factor binding protein 6 0.00691591
GOLGA8H golgin A8 family, member H 0.00689137
CLDN10 claudin 10 0.00685136
EMILIN1 elastin microfibril interfacer 1 0.00684692
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.00684001
ZW10 zw10 kinetochore protein 0.00683231
LBH limb bud and heart development 0.00683097
FLNA filamin A, alpha 0.00682229
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.00681311
OLFML3 olfactomedin-like 3 0.00680293
RIMBP2 RIMS binding protein 2 0.00679394
ZFP36L2 ZFP36 ring finger protein-like 2 0.00676683
SPRY4 sprouty homolog 4 (Drosophila) 0.00676191
GAL galanin/GMAP prepropeptide 0.00673882
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00672993
C14ORF132 chromosome 14 open reading frame 132 0.00671114
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00670689
MDFIC MyoD family inhibitor domain containing 0.00669491
PRDX2 peroxiredoxin 2 0.00669404
FBLN5 fibulin 5 0.00669248
KHSRP KH-type splicing regulatory protein 0.00668898
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00665776
JADE2 jade family PHD finger 2 0.00665685
CLC Charcot-Leyden crystal galectin 0.00665327
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00661445
GLG1 golgi glycoprotein 1 0.00661357
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00661303
GPI glucose-6-phosphate isomerase 0.00661288
ADORA2B adenosine A2b receptor 0.0065922
KANK2 KN motif and ankyrin repeat domains 2 0.00658259
FABP1 fatty acid binding protein 1, liver 0.00658177
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00656878
HEATR1 HEAT repeat containing 1 0.00655914
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00655341
RUNX3 runt-related transcription factor 3 0.00655265
ASRGL1 asparaginase like 1 0.00654856
GOLGA8A golgin A8 family, member A 0.00654144
SMAD7 SMAD family member 7 0.00650255
ZBED2 zinc finger, BED-type containing 2 0.00647665
CTSE cathepsin E 0.00646645
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00646473
MFSD10 major facilitator superfamily domain containing 10 0.00644459
TOR1A torsin family 1, member A (torsin A) 0.00643862
MRC2 mannose receptor, C type 2 0.00641674
AEBP1 AE binding protein 1 0.00641583
VCP valosin containing protein 0.00640919
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00640808
LIMCH1 LIM and calponin homology domains 1 0.00640635
ETV5 ets variant 5 0.00639732
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00639499
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00639281
CRISP3 cysteine-rich secretory protein 3 0.0063921
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00638118
CARD10 caspase recruitment domain family, member 10 0.00637848
TMEM176B transmembrane protein 176B 0.0063425
SRRT serrate, RNA effector molecule 0.00633551
BEX1 brain expressed, X-linked 1 0.00633013
PCNA proliferating cell nuclear antigen 0.00632161
VCAM1 vascular cell adhesion molecule 1 0.00629468
GEMIN4 gem (nuclear organelle) associated protein 4 0.00628293
SRPX2 sushi-repeat containing protein, X-linked 2 0.00626767
FCGBP Fc fragment of IgG binding protein 0.0062606
LAD1 ladinin 1 0.00625305
SOWAHC sosondowah ankyrin repeat domain family member C 0.00625216
SH3YL1 SH3 and SYLF domain containing 1 0.00624643
PLAU plasminogen activator, urokinase 0.00623546
CPT1A carnitine palmitoyltransferase 1A (liver) 0.0062321
SAP18 Sin3A-associated protein, 18kDa 0.00622342
BFAR bifunctional apoptosis regulator 0.00620188
PLXNA1 plexin A1 0.00617734
AMPH amphiphysin 0.0061741
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00617234
CSNK1E casein kinase 1, epsilon 0.00616625
MCM5 minichromosome maintenance complex component 5 0.00614533
DUSP6 dual specificity phosphatase 6 0.0061452
ADAM12 ADAM metallopeptidase domain 12 0.00613215
PDZD2 PDZ domain containing 2 0.00612251
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00610477
NPAS2 neuronal PAS domain protein 2 0.00608952
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.00608896
MMP28 matrix metallopeptidase 28 0.0060539
FXYD3 FXYD domain containing ion transport regulator 3 0.00605344
SPRY2 sprouty homolog 2 (Drosophila) 0.00601686
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00601509
FAM102A family with sequence similarity 102, member A 0.00599922
SPRR1B small proline-rich protein 1B 0.00599719
CARM1 coactivator-associated arginine methyltransferase 1 0.00599615
GMDS GDP-mannose 4,6-dehydratase 0.00594965
DCAF7 DDB1 and CUL4 associated factor 7 0.00594184
ZNF264 zinc finger protein 264 0.00594008
F2R coagulation factor II (thrombin) receptor 0.00593608
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.00593576
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00593492
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00593407
STK17A serine/threonine kinase 17a 0.00593177
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00592007
SELENBP1 selenium binding protein 1 0.00591932
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.00589878
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00589727
GPM6B glycoprotein M6B 0.0058859
PRKCQ protein kinase C, theta 0.00586438
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.00586435
EPHB3 EPH receptor B3 0.00586126
LMNB2 lamin B2 0.00584495
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00584198
LEFTY1 left-right determination factor 1 0.00583
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.00582156
UBXN7 UBX domain protein 7 0.00581907
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.0057969
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00579384
AHNAK2 AHNAK nucleoprotein 2 0.00578729
CEMIP cell migration inducing protein, hyaluronan binding 0.00578148
CA12 carbonic anhydrase XII 0.00577543
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00576634
BGN biglycan 0.00576329
PRMT1 protein arginine methyltransferase 1 0.00575526
ENGASE endo-beta-N-acetylglucosaminidase 0.00573603
USP11 ubiquitin specific peptidase 11 0.00573096

decreased expression

Symbol Name Standardized Value
RB1 retinoblastoma 1 -0.0252446
HIST1H2AC histone cluster 1, H2ac -0.0136522
TM4SF1 transmembrane 4 L six family member 1 -0.0129985
NIBAN1 niban apoptosis regulator 1 -0.0128809
SPTSSA serine palmitoyltransferase, small subunit A -0.0127854
SVIL supervillin -0.0126539
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0125269
TFPI2 tissue factor pathway inhibitor 2 -0.0122749
H1-2 H1.2 linker histone, cluster member -0.0120382
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.0119397
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.0116674
RGCC regulator of cell cycle -0.0116454
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.0108019
SHTN1 shootin 1 -0.0106862
ADAM9 ADAM metallopeptidase domain 9 -0.0106027
LGALS2 lectin, galactoside-binding, soluble, 2 -0.0103822
LPAR6 lysophosphatidic acid receptor 6 -0.0103725
ZBTB18 zinc finger and BTB domain containing 18 -0.0101491
TSC22D1 TSC22 domain family, member 1 -0.0100463
KYNU kynureninase -0.00989774
CPB1 carboxypeptidase B1 (tissue) -0.00985546
SNAP29 synaptosomal-associated protein, 29kDa -0.0096459
AREG amphiregulin -0.00959045
HAT1 histone acetyltransferase 1 -0.00956336
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00949461
STC2 stanniocalcin 2 -0.00948902
ARHGAP29 Rho GTPase activating protein 29 -0.00947637
HIST1H2BK histone cluster 1, H2bk -0.00935452
CD36 CD36 molecule (thrombospondin receptor) -0.00934908
KDM5A lysine (K)-specific demethylase 5A -0.00901135
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00897483
VNN1 vanin 1 -0.00895056
RELN reelin -0.00894283
COL15A1 collagen, type XV, alpha 1 -0.00892147
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00890107
SLC16A6 solute carrier family 16, member 6 -0.00888783
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00884608
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00883878
HSBP1 heat shock factor binding protein 1 -0.00876633
APOLD1 apolipoprotein L domain containing 1 -0.00872381
TMEM14B transmembrane protein 14B -0.00868184
INHBB inhibin, beta B -0.0086437
C3AR1 complement component 3a receptor 1 -0.00859894
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00855468
NID2 nidogen 2 (osteonidogen) -0.00854247
ZEB1 zinc finger E-box binding homeobox 1 -0.00843201
WSB1 WD repeat and SOCS box containing 1 -0.0084236
ACOT9 acyl-CoA thioesterase 9 -0.00839811
GSTM3 glutathione S-transferase mu 3 (brain) -0.00834665
ELOVL5 ELOVL fatty acid elongase 5 -0.00831754
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00829935
SRGN serglycin -0.00820043
ESM1 endothelial cell-specific molecule 1 -0.0080991
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0080654
DYSF dysferlin -0.00804722
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.0079698
RIN2 Ras and Rab interactor 2 -0.00795752
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00795564
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00794081
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00791391
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00790131
SGK1 serum/glucocorticoid regulated kinase 1 -0.00787674
MARCHF6 membrane associated ring-CH-type finger 6 -0.00783744
NOTCH2 notch 2 -0.00780054
PLPP3 phospholipid phosphatase 3 -0.00777438
APOB apolipoprotein B -0.00774704
JCHAIN joining chain of multimeric IgA and IgM -0.00770306
DLK1 delta-like 1 homolog (Drosophila) -0.00769545
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00767112
EVI2A ecotropic viral integration site 2A -0.00763644
ACP3 acid phosphatase 3 -0.00763295
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00762223
CCNG2 cyclin G2 -0.0075996
TXNIP thioredoxin interacting protein -0.00759918
MAOA monoamine oxidase A -0.00759498
SAR1B secretion associated, Ras related GTPase 1B -0.00758401
CHIC2 cysteine-rich hydrophobic domain 2 -0.00757075
METTL5 methyltransferase like 5 -0.0074983
NDFIP1 Nedd4 family interacting protein 1 -0.00747215
OGFRL1 opioid growth factor receptor-like 1 -0.00746136
SCD5 stearoyl-CoA desaturase 5 -0.0073923
GLRX2 glutaredoxin 2 -0.00738234
RNF13 ring finger protein 13 -0.00737608
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -0.00736919
PER1 period circadian clock 1 -0.00736073
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00733975
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -0.00733806
GYG1 glycogenin 1 -0.00730755
ACVR1 activin A receptor, type I -0.00724754
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00719516
PIP prolactin-induced protein -0.00717963
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -0.00716024
USP3 ubiquitin specific peptidase 3 -0.00715684
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00715151
BBIP1 BBSome interacting protein 1 -0.00714695
VEGFC vascular endothelial growth factor C -0.00712702
VWF von Willebrand factor -0.00710762
BTBD3 BTB (POZ) domain containing 3 -0.00710227
COL4A5 collagen, type IV, alpha 5 -0.00707388
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -0.00705681
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00702593
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00702279
SC5D sterol-C5-desaturase -0.00702196
HK2 hexokinase 2 -0.00702117
APOD apolipoprotein D -0.0070203
CLEC2B C-type lectin domain family 2, member B -0.00701207
SELENOF selenoprotein F -0.00699347
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00696333
WWTR1 WW domain containing transcription regulator 1 -0.00695483
FN1 fibronectin 1 -0.00694014
IGFBP1 insulin-like growth factor binding protein 1 -0.00692399
HSPB8 heat shock 22kDa protein 8 -0.00691631
CREM cAMP responsive element modulator -0.00689926
SOCS5 suppressor of cytokine signaling 5 -0.00688571
MOB4 MOB family member 4, phocein -0.00688034
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00687717
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00685148
NEU1 sialidase 1 (lysosomal sialidase) -0.00684843
C1QA complement component 1, q subcomponent, A chain -0.0068419
FBXL5 F-box and leucine-rich repeat protein 5 -0.00682712
MRPL40 mitochondrial ribosomal protein L40 -0.00679717
MCFD2 multiple coagulation factor deficiency 2 -0.00679041
NCKAP1 NCK-associated protein 1 -0.00678887
CCL8 chemokine (C-C motif) ligand 8 -0.00677439
HPSE heparanase -0.00676189
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit -0.0067549
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00673183
NAV3 neuron navigator 3 -0.00672974
LAMP2 lysosomal-associated membrane protein 2 -0.00672959
MET MET proto-oncogene, receptor tyrosine kinase -0.00672187
HHEX hematopoietically expressed homeobox -0.00669556
CCNH cyclin H -0.00669489
PRAME preferentially expressed antigen in melanoma -0.00667869
HIST1H2BD histone cluster 1, H2bd -0.0066681
FAM198B family with sequence similarity 198, member B -0.0066207
NAMPT nicotinamide phosphoribosyltransferase -0.00661681
ARMT1 acidic residue methyltransferase 1 -0.00661541
RHOB ras homolog family member B -0.00661485
VAMP7 vesicle-associated membrane protein 7 -0.006588
ARG2 arginase 2 -0.00657205
FNDC3A fibronectin type III domain containing 3A -0.00656076
KLHL24 kelch-like family member 24 -0.00652978
TRIM13 tripartite motif containing 13 -0.00652132
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00651607
BEX4 brain expressed, X-linked 4 -0.00650715
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00649387
HSPB6 heat shock protein, alpha-crystallin-related, B6 -0.00648187
CLEC7A C-type lectin domain family 7, member A -0.00647453
SSX1 synovial sarcoma, X breakpoint 1 -0.00644919
NFU1 NFU1 iron-sulfur cluster scaffold -0.00643188
AKR1C1 aldo-keto reductase family 1, member C1 -0.00642362
IRS1 insulin receptor substrate 1 -0.00641109
EAPP E2F-associated phosphoprotein -0.0063961
STX12 syntaxin 12 -0.00639503
TMEM165 transmembrane protein 165 -0.00639396
MAGEA3 melanoma antigen family A3 -0.0063931
KLHL21 kelch-like family member 21 -0.0063795
PFN2 profilin 2 -0.00637873
GDF15 growth differentiation factor 15 -0.00635731
EPCAM epithelial cell adhesion molecule -0.00635444
IFRD1 interferon-related developmental regulator 1 -0.00635344
SCARB2 scavenger receptor class B, member 2 -0.00634501
UBE2B ubiquitin-conjugating enzyme E2B -0.00631384
NPM3 nucleophosmin/nucleoplasmin 3 -0.00631003
NMU neuromedin U -0.00629523
NOTCH2NL notch 2 N-terminal like -0.0062944
C1D C1D nuclear receptor corepressor -0.00628803
NRIP3 nuclear receptor interacting protein 3 -0.00628254
MB myoglobin -0.00627937
ADGRL4 adhesion G protein-coupled receptor L4 -0.00627217
PLIN1 perilipin 1 -0.00627071
GOLT1B golgi transport 1B -0.00626808
PXDC1 PX domain containing 1 -0.00626559
RAB7A RAB7A, member RAS oncogene family -0.00626558
KIF1B kinesin family member 1B -0.00625835
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00624572
HBZ hemoglobin, zeta -0.00624493
PDCD10 programmed cell death 10 -0.00623911
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00623394
AQP9 aquaporin 9 -0.00622808
ARL4A ADP-ribosylation factor-like 4A -0.00622609
MYO1B myosin IB -0.00622315
YAP1 Yes-associated protein 1 -0.00621904
MED7 mediator complex subunit 7 -0.00621118
PHYH phytanoyl-CoA 2-hydroxylase -0.00620705
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -0.0062006
ERBIN erbb2 interacting protein -0.00618584
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00618111
IFT57 intraflagellar transport 57 -0.00617841
SGMS1 sphingomyelin synthase 1 -0.00617143
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.006171
FRMD4B FERM domain containing 4B -0.00616937
PTBP2 polypyrimidine tract binding protein 2 -0.00615007
SEC23A Sec23 homolog A (S. cerevisiae) -0.00613769
CAV2 caveolin 2 -0.00612925
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00611731
GSTO1 glutathione S-transferase omega 1 -0.00611603
GIMAP4 GTPase, IMAP family member 4 -0.00611461
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00610256
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00609739
DUSP14 dual specificity phosphatase 14 -0.00608373
ORM1 orosomucoid 1 -0.00606077
SMS spermine synthase -0.00605507
ODR4 odr-4 GPCR localization factor homolog -0.0060535
ANKRD28 ankyrin repeat domain 28 -0.00605111
ATP7A ATPase, Cu++ transporting, alpha polypeptide -0.00603718
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -0.00602909
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00602539
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00601796
PFDN4 prefoldin subunit 4 -0.00601544
ASB13 ankyrin repeat and SOCS box containing 13 -0.00601343
TM7SF2 transmembrane 7 superfamily member 2 -0.00598501
IL6ST interleukin 6 signal transducer -0.00598467
UFD1 ubiquitin recognition factor in ER associated degradation 1 -0.0059775
CCL20 chemokine (C-C motif) ligand 20 -0.00597543
GLRX glutaredoxin (thioltransferase) -0.00596483
SORD sorbitol dehydrogenase -0.00596019
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00595672
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -0.00595563
ENO3 enolase 3 (beta, muscle) -0.00595538
TLK1 tousled-like kinase 1 -0.00594972
LRP2 low density lipoprotein receptor-related protein 2 -0.00593597
NPTX1 neuronal pentraxin I -0.00591201
RPL23AP7 ribosomal protein L23a pseudogene 7 -0.00590912
ADK adenosine kinase -0.00590314
TWF1 twinfilin actin binding protein 1 -0.0058905
C6ORF48 chromosome 6 open reading frame 48 -0.00587812
AKR1C2 aldo-keto reductase family 1, member C2 -0.00587574
SNRPG small nuclear ribonucleoprotein polypeptide G -0.00586423
SPARCL1 SPARC-like 1 (hevin) -0.00585035
RDX radixin -0.00584978
WFDC2 WAP four-disulfide core domain 2 -0.00584807
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00584267
AADAC arylacetamide deacetylase -0.0058333
CIDEC cell death-inducing DFFA-like effector c -0.0058311
DHDDS dehydrodolichyl diphosphate synthase -0.00582426
CCDC85B coiled-coil domain containing 85B -0.00579241
NFE2 nuclear factor, erythroid 2 -0.00578944
PRCP prolylcarboxypeptidase (angiotensinase C) -0.00578088
HIST1H2AE histone cluster 1, H2ae -0.00575401
C5ORF28 chromosome 5 open reading frame 28 -0.00575016
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -0.0057498
CD9 CD9 molecule -0.00573998
PALMD palmdelphin -0.00573804
UBB ubiquitin B -0.00573422
C1ORF115 chromosome 1 open reading frame 115 -0.00572542
IL1R2 interleukin 1 receptor, type II -0.00572121
CYBRD1 cytochrome b reductase 1 -0.00566652
NGRN neugrin, neurite outgrowth associated -0.00566316
TPRKB TP53RK binding protein -0.00565655