PAIP1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description poly(A) binding protein interacting protein 1|The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10605)
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Genes

279 genes differentially expressed following the PAIP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TAS2R3 taste receptor, type 2, member 3 2.43117
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.43117
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.43117
FRK fyn-related Src family tyrosine kinase 2.43117
TAS1R1 taste receptor, type 1, member 1 2.43117
NRAP nebulin-related anchoring protein 2.43117
THSD1 thrombospondin, type I, domain containing 1 2.43117
ATP11C ATPase, class VI, type 11C 2.43117
PLVAP plasmalemma vesicle associated protein 2.43117
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.43117
HSPB2 heat shock 27kDa protein 2 2.43117
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.43117
OR6F1 olfactory receptor, family 6, subfamily F, member 1 2.43117
SYTL4 synaptotagmin-like 4 2.43117
RHEX regulator of hemoglobinization and erythroid cell expansion 2.43117
ZNF804A zinc finger protein 804A 2.43117
MOBP myelin-associated oligodendrocyte basic protein 2.43117
GJB6 gap junction protein, beta 6, 30kDa 2.43117
FAM240C family with sequence similarity 240 member C 2.43117
SCGN secretagogin, EF-hand calcium binding protein 2.35661
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 2.35661
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.35661
SCGB3A1 secretoglobin, family 3A, member 1 2.35661
PDIA2 protein disulfide isomerase family A, member 2 2.35661
WNT8B wingless-type MMTV integration site family, member 8B 2.35661
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 2.35661
SRPX2 sushi-repeat containing protein, X-linked 2 2.35661
SIX2 SIX homeobox 2 2.35661
HLF hepatic leukemia factor 2.35661
ZACN zinc activated ligand-gated ion channel 2.35661
TMEM52B transmembrane protein 52B 2.35661
TMCO5A transmembrane and coiled-coil domains 5A 2.35661
HBZ hemoglobin, zeta 2.35661
ZNF19 zinc finger protein 19 2.35661
ZNF669 zinc finger protein 669 2.35661
ZNF668 zinc finger protein 668 2.35661
HORMAD1 HORMA domain containing 1 2.35661
TMEM72 transmembrane protein 72 2.35661
TDRD6 tudor domain containing 6 2.35661
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.35661
H2BW2 H2B.W histone 2 2.35661
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.35661
MYBPC3 myosin binding protein C, cardiac 2.35661
AVPR2 arginine vasopressin receptor 2 2.35661
TRIM42 tripartite motif containing 42 2.35661
RFPL2 ret finger protein-like 2 2.35661
MYOM2 myomesin 2 2.35661
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.35661
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 2.35661
GSTM5 glutathione S-transferase mu 5 2.35661
TCP11 t-complex 11, testis-specific 2.35661
SH2D6 SH2 domain containing 6 2.35661
PDZD9 PDZ domain containing 9 2.35661
DLL4 delta-like 4 (Drosophila) 2.35661
ARRDC5 arrestin domain containing 5 2.35661
LOC124903317 uncharacterized LOC124903317 2.35661
VSIR V-set immunoregulatory receptor 2.35661
CAPN9 calpain 9 2.35661
STMN4 stathmin-like 4 2.35661
IGSF22 immunoglobulin superfamily, member 22 2.35661
OR1C1 olfactory receptor, family 1, subfamily C, member 1 2.35661
MYPN myopalladin 2.35661
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.35661
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 2.35661
RTL9 retrotransposon Gag like 9 2.35661
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 2.35661
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.35661
SPATA31G1 SPATA31 subfamily G member 1 2.35661
OR56B2 olfactory receptor family 56 subfamily B member 2 2.35661
SPMIP3 sperm microtubule inner protein 3 2.35661
EZHIP EZH inhibitory protein 2.35661
CFAP276 cilia and flagella associated protein 276 2.35661
CPHXL cytoplasmic polyadenylated homeobox like 2.35661
H2BC3 H2B clustered histone 3 2.35661
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 2.35661
LRRN4CL LRRN4 C-terminal like 2.35661
LTF lactotransferrin 2.35661
DEFB1 defensin, beta 1 2.35661
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.35661
SLFN14 schlafen family member 14 2.35661
OR2A2 olfactory receptor, family 2, subfamily A, member 2 2.35661
CPNE6 copine VI (neuronal) 2.35661
FPR2 formyl peptide receptor 2 2.35661
SYCP1 synaptonemal complex protein 1 2.35661
TAS2R9 taste receptor, type 2, member 9 2.35661
GHSR growth hormone secretagogue receptor 2.35661
LIX1 Lix1 homolog (chicken) 2.35661
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.35661
FGFBP2 fibroblast growth factor binding protein 2 2.35661
STARD6 StAR-related lipid transfer (START) domain containing 6 2.35661
BLNK B-cell linker 2.35661
CLDN24 claudin 24 2.35661
ARMS2 age-related maculopathy susceptibility 2 2.35661
CFAP45 cilia and flagella associated protein 45 2.35661
GOLGA7B golgin A7 family, member B 2.35661
GPR4 G protein-coupled receptor 4 2.35661
HHIPL2 HHIP-like 2 2.35661
HHATL hedgehog acyltransferase-like 2.35661
STK38L serine/threonine kinase 38 like 2.35661
SMIM24 small integral membrane protein 24 2.35661
IER3IP1 immediate early response 3 interacting protein 1 2.35661
EMX2 empty spiracles homeobox 2 2.35661
BPIFB3 BPI fold containing family B, member 3 2.35661
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 2.35661
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 2.35661
EHF ets homologous factor 2.35661
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.35661
POF1B premature ovarian failure, 1B 2.35661
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.35661
LST1 leukocyte specific transcript 1 2.35661
DBX2 developing brain homeobox 2 2.35661
HAMP hepcidin antimicrobial peptide 2.35661
CT55 cancer/testis antigen 55 2.35661
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.35661
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 2.35661
CST1 cystatin SN 2.35661
TRIM50 tripartite motif containing 50 2.35661
ODF4 outer dense fiber of sperm tails 4 2.35661
IGLL1 immunoglobulin lambda-like polypeptide 1 2.35661
GOLGA8M golgin A8 family, member M 2.35661
DCN decorin 2.35661
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 2.35661
RBBP8NL RBBP8 N-terminal like 2.35661
RAB6C RAB6C, member RAS oncogene family 2.35661
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.35661
TM4SF19 transmembrane 4 L six family member 19 2.35661
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 2.35661
AFF4 AF4/FMR2 family, member 4 2.35661
OR14J1 olfactory receptor, family 14, subfamily J, member 1 2.35661
DHH desert hedgehog 2.35661
EGR3 early growth response 3 2.35661
NTSR2 neurotensin receptor 2 2.35661
KLK6 kallikrein-related peptidase 6 2.35661
TRAPPC9 trafficking protein particle complex 9 2.35661
PRR35 proline rich 35 2.35661
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.35661
DLX2 distal-less homeobox 2 2.35661
C22ORF31 chromosome 22 open reading frame 31 2.35661
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.35661
TAS2R43 taste receptor, type 2, member 43 2.35661
ZPLD1 zona pellucida-like domain containing 1 2.35661
RBP4 retinol binding protein 4, plasma 2.35661
ANXA1 annexin A1 2.35661
THEMIS thymocyte selection associated 2.35661
STEAP4 STEAP family member 4 2.35661
FAM9C family with sequence similarity 9, member C 2.35661
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 2.35661
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 2.35661
OR51I2 olfactory receptor, family 51, subfamily I, member 2 2.35661
SENP7 SUMO1/sentrin specific peptidase 7 2.35661
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.35661
NRGN neurogranin (protein kinase C substrate, RC3) 2.35661
R3HDML R3H domain containing-like 2.35661
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.35661
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 2.35661
MEIG1 meiosis/spermiogenesis associated 1 2.35661
ACY3 aminoacylase 3 2.35661
C2ORF78 chromosome 2 open reading frame 78 2.35661
CCNO cyclin O 2.35661
TMPRSS13 transmembrane protease, serine 13 2.35661
HMX3 H6 family homeobox 3 2.35661
CCDC166 coiled-coil domain containing 166 2.35661
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.35661
SPACA3 sperm acrosome associated 3 2.35661
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.35661
CD8A CD8a molecule 2.35661
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 2.35661
ZNF638 zinc finger protein 638 2.32821
TPPP tubulin polymerization promoting protein 2.27061
RGS8 regulator of G-protein signaling 8 2.27061
NXPH3 neurexophilin 3 2.27061
CELF6 CUGBP, Elav-like family member 6 2.27061
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.27061
CACFD1 calcium channel flower domain containing 1 2.26088
SPX spexin hormone 2.24655
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 2.24655
DHRS4 dehydrogenase/reductase (SDR family) member 4 2.24651
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 2.23771
CFAP68 cilia and flagella associated protein 68 2.21747
IGIP IgA-inducing protein 2.21614
COPS2 COP9 signalosome subunit 2 2.2117
GLRA1 glycine receptor, alpha 1 2.19154
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.18582
YTHDC2 YTH domain containing 2 2.17904
TBC1D28 TBC1 domain family, member 28 2.17904
FAAP100 FA core complex associated protein 100 2.15217
LENG9 leukocyte receptor cluster (LRC) member 9 2.13584
CCPG1 cell cycle progression 1 2.1086
RPL7L1 ribosomal protein L7-like 1 2.1086
PRMT7 protein arginine methyltransferase 7 2.1005
UBQLN1 ubiquilin 1 2.0946
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 2.09449
CNOT6 CCR4-NOT transcription complex, subunit 6 2.07951
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 2.06188
SMTNL2 smoothelin-like 2 2.06188
MST1R macrophage stimulating 1 receptor 2.04288
MLYCD malonyl-CoA decarboxylase 2.02777
ZNF665 zinc finger protein 665 2.00146

decreased expression

Symbol Name Standardized Value
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 -2.43117
TMEM229A transmembrane protein 229A -2.43117
SHISA7 shisa family member 7 -2.43117
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 -2.43117
SF3A2 splicing factor 3a, subunit 2, 66kDa -2.43117
PLGLB1 plasminogen-like B1 -2.43117
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -2.43117
TSC22D1 TSC22 domain family, member 1 -2.35661
LDHC lactate dehydrogenase C -2.35661
C1ORF146 chromosome 1 open reading frame 146 -2.35661
TMC3 transmembrane channel-like 3 -2.35661
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 -2.35661
DYNAP dynactin associated protein -2.35661
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -2.35661
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) -2.35661
HAS1 hyaluronan synthase 1 -2.35661
LRG1 leucine-rich alpha-2-glycoprotein 1 -2.35661
AJM1 apical junction component 1 homolog -2.35661
CFAP119 cilia and flagella associated protein 119 -2.35661
PLAAT2 phospholipase A and acyltransferase 2 -2.35661
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 -2.35661
LOC112694756 uncharaterized LOC112694756 -2.35661
PDF peptide deformylase (mitochondrial) -2.35661
OOSP1 oocyte secreted protein 1, pseudogene -2.35661
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 -2.35661
INKA2 inka box actin regulator 2 -2.35661
PTPRH protein tyrosine phosphatase, receptor type, H -2.35661
FOXD1 forkhead box D1 -2.35661
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 -2.35661
MYL5 myosin, light chain 5, regulatory -2.35661
SPON2 spondin 2, extracellular matrix protein -2.35661
ANKRD37 ankyrin repeat domain 37 -2.35661
EMP1 epithelial membrane protein 1 -2.35661
LCNL1 lipocalin-like 1 -2.35661
RNFT1 ring finger protein, transmembrane 1 -2.35661
IFI35 interferon-induced protein 35 -2.35661
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.35661
PDCD1LG2 programmed cell death 1 ligand 2 -2.35661
CHKB choline kinase beta -2.35661
EGR2 early growth response 2 -2.35661
CNR2 cannabinoid receptor 2 (macrophage) -2.35661
FNDC8 fibronectin type III domain containing 8 -2.35661
HSPB8 heat shock 22kDa protein 8 -2.35661
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -2.35661
SNAP91 synaptosomal-associated protein, 91kDa -2.35661
SMCO2 single-pass membrane protein with coiled-coil domains 2 -2.35661
PAIP1 poly(A) binding protein interacting protein 1 -2.35661
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 -2.35661
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 -2.31077
RAB23 RAB23, member RAS oncogene family -2.31077
TUT4 terminal uridylyl transferase 4 -2.28524
C10ORF88 chromosome 10 open reading frame 88 -2.27061
ZIC3 Zic family member 3 -2.27061
TRAM1L1 translocation associated membrane protein 1-like 1 -2.24835
KEAP1 kelch-like ECH-associated protein 1 -2.24512
SREBF1 sterol regulatory element binding transcription factor 1 -2.24512
PRR19 proline rich 19 -2.21502
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.21369
XRRA1 X-ray radiation resistance associated 1 -2.21126
WIPF3 WAS/WASL interacting protein family, member 3 -2.19683
VWCE von Willebrand factor C and EGF domains -2.19683
MAST2 microtubule associated serine/threonine kinase 2 -2.18795
DNAI2 dynein, axonemal, intermediate chain 2 -2.16398
KLHDC10 kelch domain containing 10 -2.14361
MTMR7 myotubularin related protein 7 -2.12357
GRB2 growth factor receptor-bound protein 2 -2.1086
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -2.10819
OR2A7 olfactory receptor, family 2, subfamily A, member 7 -2.09582
MYO18B myosin XVIIIB -2.09582
RAG2 recombination activating gene 2 -2.09582
ZNF704 zinc finger protein 704 -2.0946
OLFM2 olfactomedin 2 -2.07969
CNGA1 cyclic nucleotide gated channel alpha 1 -2.07672
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -2.0713
RNF157 ring finger protein 157 -2.06517
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -2.06226
MMP16 matrix metallopeptidase 16 (membrane-inserted) -2.06188
MMP28 matrix metallopeptidase 28 -2.05203
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -2.01896
RELT RELT tumor necrosis factor receptor -2.00146
WDR19 WD repeat domain 19 -2.00146