| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | poly(A) binding protein interacting protein 2B|Most mRNAs, except for histones, contain a 3-prime poly(A) tail. Poly(A)-binding protein (PABP; see MIM 604679) enhances translation by circularizing mRNA through its interaction with the translation initiation factor EIF4G1 (MIM 600495) and the poly(A) tail. Various PABP-binding proteins regulate PABP activity, including PAIP1 (MIM 605184), a translational stimulator, and PAIP2A (MIM 605604) and PAIP2B, translational inhibitors (Derry et al., 2006 [PubMed 17381337]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 400961) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/400961 |
| Similar Terms | |
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2 interacting proteins for PAIP2B from the Pathway Commons Protein-Protein Interactions dataset.
