PAK1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description p21 protein (Cdc42/Rac)-activated kinase 1|This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] (NCBI Entrez Gene Database, 5058)
Similar Terms
Downloads & Tools

Genes

425 genes differentially expressed following the PAK1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 2.96702
PDYN prodynorphin 2.96702
HES4 hes family bHLH transcription factor 4 2.96702
OSGIN1 oxidative stress induced growth inhibitor 1 2.96702
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.96702
CCDC63 coiled-coil domain containing 63 2.96702
EPB42 erythrocyte membrane protein band 4.2 2.96702
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.96702
PAX3 paired box 3 2.96702
SLC15A5 solute carrier family 15, member 5 2.96702
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.96702
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.96702
SSMEM1 serine-rich single-pass membrane protein 1 2.96702
XCL1 chemokine (C motif) ligand 1 2.96702
CELA3A chymotrypsin-like elastase family, member 3A 2.96702
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.96702
CD160 CD160 molecule 2.96702
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.96702
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 2.96702
CLEC12A C-type lectin domain family 12, member A 2.96702
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.96702
NPPC natriuretic peptide C 2.96702
SLC46A2 solute carrier family 46, member 2 2.96702
IGFL3 IGF-like family member 3 2.96702
CD1D CD1d molecule 2.96702
TMEM176A transmembrane protein 176A 2.96702
SCGB3A1 secretoglobin, family 3A, member 1 2.96702
BTC betacellulin 2.96702
TRIM15 tripartite motif containing 15 2.96702
CD163 CD163 molecule 2.96702
TUBB1 tubulin, beta 1 class VI 2.96702
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.96702
SNAP25 synaptosomal-associated protein, 25kDa 2.96702
HARBI1 harbinger transposase derived 1 2.96702
HES2 hes family bHLH transcription factor 2 2.96702
EPHB3 EPH receptor B3 2.96702
NKD2 naked cuticle homolog 2 (Drosophila) 2.96702
BTBD18 BTB (POZ) domain containing 18 2.96702
MARVELD3 MARVEL domain containing 3 2.96702
METTL21C methyltransferase like 21C 2.96702
TMEM184A transmembrane protein 184A 2.96702
MEIG1 meiosis/spermiogenesis associated 1 2.96702
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 2.96702
GALP galanin-like peptide 2.96702
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.96702
IRX5 iroquois homeobox 5 2.96702
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 2.96702
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.96702
FAM110D family with sequence similarity 110, member D 2.96702
GPR20 G protein-coupled receptor 20 2.96702
FRA10AC1 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 2.96702
SERF1B small EDRK-rich factor 1B (centromeric) 2.96702
RFPL3 ret finger protein-like 3 2.96702
ASMT acetylserotonin O-methyltransferase 2.96702
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.96702
PARP10 poly (ADP-ribose) polymerase family, member 10 2.96702
NEUROG3 neurogenin 3 2.96702
GMNC geminin coiled-coil domain containing 2.96702
SHD Src homology 2 domain containing transforming protein D 2.96702
S100A5 S100 calcium binding protein A5 2.96702
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.96702
MMP20 matrix metallopeptidase 20 2.96702
SGK2 serum/glucocorticoid regulated kinase 2 2.96702
CPNE8-AS1 CPNE8 antisense RNA 1 2.96702
CXCL13 chemokine (C-X-C motif) ligand 13 2.96702
BNC1 basonuclin 1 2.96702
DUSP9 dual specificity phosphatase 9 2.96702
STX11 syntaxin 11 2.96702
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.96702
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 2.96702
TMPRSS6 transmembrane protease, serine 6 2.96702
TSPAN8 tetraspanin 8 2.96702
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.96702
SPATA25 spermatogenesis associated 25 2.96702
GPR37L1 G protein-coupled receptor 37 like 1 2.96702
F5 coagulation factor V (proaccelerin, labile factor) 2.96702
GATA3 GATA binding protein 3 2.96702
PNLIPRP1 pancreatic lipase-related protein 1 2.96702
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.96702
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.96702
LOC124900467 uncharacterized LOC124900467 2.96702
LOC124906010 uncharacterized LOC124906010 2.96702
SMIM43 small integral membrane protein 43 2.96702
H3C14 H3 clustered histone 14 2.96702
LY6L lymphocyte antigen 6 family member L 2.96702
CFAP141 cilia and flagella associated protein 141 2.96702
WDR97 WD repeat domain 97 2.96702
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.96702
CLXN calaxin 2.96702
CCDC198 coiled-coil domain containing 198 2.96702
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.96702
CCN5 cellular communication network factor 5 2.96702
SMIM41 small integral membrane protein 41 2.96702
GATA6 GATA binding protein 6 2.96702
RNF186 ring finger protein 186 2.96702
DLK1 delta-like 1 homolog (Drosophila) 2.96702
CCR6 chemokine (C-C motif) receptor 6 2.96702
AMBP alpha-1-microglobulin/bikunin precursor 2.96702
IRF8 interferon regulatory factor 8 2.96702
IRF5 interferon regulatory factor 5 2.96702
PCDHB13 protocadherin beta 13 2.96702
ISG15 ISG15 ubiquitin-like modifier 2.96702
PCDHA6 protocadherin alpha 6 2.96702
TMEM229A transmembrane protein 229A 2.96702
ATP13A4 ATPase type 13A4 2.96702
NRN1 neuritin 1 2.96702
PLVAP plasmalemma vesicle associated protein 2.96702
TMPRSS11B transmembrane protease, serine 11B 2.96702
TMPRSS11A transmembrane protease, serine 11A 2.96702
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.96702
COL6A6 collagen, type VI, alpha 6 2.96702
CD79A CD79a molecule, immunoglobulin-associated alpha 2.96702
ASIC3 acid sensing (proton gated) ion channel 3 2.96702
GPR137 G protein-coupled receptor 137 2.96702
FGFBP2 fibroblast growth factor binding protein 2 2.96702
SAA4 serum amyloid A4, constitutive 2.96702
PGLYRP1 peptidoglycan recognition protein 1 2.96702
PGLYRP2 peptidoglycan recognition protein 2 2.96702
OVOL1 ovo-like zinc finger 1 2.96702
CFAP45 cilia and flagella associated protein 45 2.96702
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.96702
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.96702
TPTE transmembrane phosphatase with tensin homology 2.96702
TLR5 toll-like receptor 5 2.96702
HLA-DRA major histocompatibility complex, class II, DR alpha 2.96702
FOLR1 folate receptor 1 (adult) 2.96702
NEUROD1 neuronal differentiation 1 2.96702
TBC1D28 TBC1 domain family, member 28 2.96702
C11ORF91 chromosome 11 open reading frame 91 2.96702
KRT222 keratin 222, type II 2.96702
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.96702
CDHR4 cadherin-related family member 4 2.96702
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.96702
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 2.96702
PLET1 placenta expressed transcript 1 2.96702
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 2.96702
SPATA3 spermatogenesis associated 3 2.96702
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.96702
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 2.96702
S100A14 S100 calcium binding protein A14 2.96702
ADGRA1 adhesion G protein-coupled receptor A1 2.96702
UBQLNL ubiquilin-like 2.96702
SHOX short stature homeobox 2.96702
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 2.96702
DYTN dystrotelin 2.96702
RPA4 replication protein A4, 30kDa 2.96702
FNDC1 fibronectin type III domain containing 1 2.96702
FNDC9 fibronectin type III domain containing 9 2.96702
RSAD2 radical S-adenosyl methionine domain containing 2 2.96702
SOWAHA sosondowah ankyrin repeat domain family member A 2.96702
RNF112 ring finger protein 112 2.96702
EDN1 endothelin 1 2.96702
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.96702
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.96702
LMOD2 leiomodin 2 (cardiac) 2.96702
CER1 cerberus 1, DAN family BMP antagonist 2.96702
PGR progesterone receptor 2.96702
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.96702
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.96702
MEIS1 Meis homeobox 1 2.96702
HLA-DMB major histocompatibility complex, class II, DM beta 2.96702
CCDC78 coiled-coil domain containing 78 2.96702
ZNF835 zinc finger protein 835 2.96702
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 2.96702
GJC2 gap junction protein, gamma 2, 47kDa 2.96702
BTG4 B-cell translocation gene 4 2.96702
GOLGA8N golgin A8 family, member N 2.96702
DND1 DND microRNA-mediated repression inhibitor 1 2.96702
DAW1 dynein assembly factor with WDR repeat domains 1 2.96702
PENK proenkephalin 2.96702
SCARF1 scavenger receptor class F, member 1 2.96702
SLC22A24 solute carrier family 22, member 24 2.96702
KLK7 kallikrein-related peptidase 7 2.96702
CHIT1 chitinase 1 (chitotriosidase) 2.96702
HLA-DOB major histocompatibility complex, class II, DO beta 2.96702
ITGB7 integrin, beta 7 2.96702
RBM24 RNA binding motif protein 24 2.96702
AMN amnion associated transmembrane protein 2.96702
AMH anti-Mullerian hormone 2.96702
SCNN1B sodium channel, non voltage gated 1 beta subunit 2.96702
GPR62 G protein-coupled receptor 62 2.96702
NPPA natriuretic peptide A 2.96702
LRRC31 leucine rich repeat containing 31 2.96702
NTNG2 netrin G2 2.96702
PTCRA pre T-cell antigen receptor alpha 2.96702
PADI6 peptidyl arginine deiminase, type VI 2.96702
TGM5 transglutaminase 5 2.96702
SLITRK6 SLIT and NTRK-like family, member 6 2.96702
TGM4 transglutaminase 4 2.96702
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.96702
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.96702
PXT1 peroxisomal, testis specific 1 2.96702
SCN3B sodium channel, voltage gated, type III beta subunit 2.96702
ZNF737 zinc finger protein 737 2.96702
TGM2 transglutaminase 2 2.96702
APOL6 apolipoprotein L, 6 2.96702
TMEM86B transmembrane protein 86B 2.96702
IFNE interferon, epsilon 2.96702
GPNMB glycoprotein (transmembrane) nmb 2.96702
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 2.96702
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.96702
ZNF774 zinc finger protein 774 2.96702
IL37 interleukin 37 2.96702
DNAH8 dynein, axonemal, heavy chain 8 2.96702
PLGLB2 plasminogen-like B2 2.96702
GPR179 G protein-coupled receptor 179 2.96702
TMEM88 transmembrane protein 88 2.96702
ZNF396 zinc finger protein 396 2.96702
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.96702
STMND1 stathmin domain containing 1 2.96702
ADIRF adipogenesis regulatory factor 2.96702
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 2.96702
AHSG alpha-2-HS-glycoprotein 2.96702
NUTM2G NUT family member 2G 2.96702
H2AC8 H2A clustered histone 8 2.8891
KIFC2 kinesin family member C2 2.88443
GUCA1B guanylate cyclase activator 1B (retina) 2.88443
RPL24 ribosomal protein L24 2.87986
CLN3 ceroid-lipofuscinosis, neuronal 3 2.81601
BAG1 BCL2-associated athanogene 2.81601
RGS14 regulator of G-protein signaling 14 2.79319
RPL28 ribosomal protein L28 2.76611
OLFM1 olfactomedin 1 2.76611
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 2.75384
CXORF38 chromosome X open reading frame 38 2.69704
LYSMD1 LysM, putative peptidoglycan-binding, domain containing 1 2.67965
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.63813
TRIM7 tripartite motif containing 7 2.63813
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 2.62667
LYPLA1 lysophospholipase I 2.6247
STUM stum, mechanosensory transduction mediator homolog 2.61837
NDFIP1 Nedd4 family interacting protein 1 2.59414
ZBTB4 zinc finger and BTB domain containing 4 2.5937
TFEB transcription factor EB 2.57902
LTA4H leukotriene A4 hydrolase 2.53062
FRMD6 FERM domain containing 6 2.53062
LNP1 leukemia NUP98 fusion partner 1 2.48684
CYB5D2 cytochrome b5 domain containing 2 2.46294
HPD 4-hydroxyphenylpyruvate dioxygenase 2.45265
GJB5 gap junction protein, beta 5, 31.1kDa 2.45265
DUSP29 dual specificity phosphatase 29 2.45265
KHSRP KH-type splicing regulatory protein 2.4352
DDB2 damage-specific DNA binding protein 2, 48kDa 2.42051
POLB polymerase (DNA directed), beta 2.40861
RPL12 ribosomal protein L12 2.40034
PRAM1 PML-RARA regulated adaptor molecule 1 2.40034
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.40034
PTMA prothymosin, alpha 2.35212
B3GAT2 beta-1,3-glucuronyltransferase 2 2.35088
DOK4 docking protein 4 2.35063
ADCY3 adenylate cyclase 3 2.33941
INTS6 integrator complex subunit 6 2.31739
RPS27L ribosomal protein S27-like 2.3168
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 2.27651
CATSPERG catsper channel auxiliary subunit gamma 2.25977
STXBP5 syntaxin binding protein 5 (tomosyn) 2.24791
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.22974
TMLHE trimethyllysine hydroxylase, epsilon 2.2237
NMU neuromedin U 2.22258
AMER1 APC membrane recruitment protein 1 2.19843
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 2.18595
KRT8 keratin 8, type II 2.18595
TSPYL5 TSPY-like 5 2.18595
MEF2B myocyte enhancer factor 2B 2.18542
POLG polymerase (DNA directed), gamma 2.1854
MCM8 minichromosome maintenance complex component 8 2.1854
EXTL2 exostosin-like glycosyltransferase 2 2.18264
H2BC5 H2B clustered histone 5 2.17798
SEC24B SEC24 family member B 2.16603
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 2.15754
RIOK3 RIO kinase 3 2.14502
SGK1 serum/glucocorticoid regulated kinase 1 2.14464
MSMO1 methylsterol monooxygenase 1 2.12586
ATP5F1D ATP synthase F1 subunit delta 2.12298
MSH5 mutS homolog 5 2.10851
TFPI2 tissue factor pathway inhibitor 2 2.10489
MTFP1 mitochondrial fission process 1 2.0982
RUVBL2 RuvB-like AAA ATPase 2 2.08956
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.08953
ABHD6 abhydrolase domain containing 6 2.07996
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.07885
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.06723
KCNIP1 Kv channel interacting protein 1 2.06242
ARHGAP44 Rho GTPase activating protein 44 2.06206
ARMC1 armadillo repeat containing 1 2.06206
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 2.06206
MAN2A2 mannosidase, alpha, class 2A, member 2 2.06206
RPS6 ribosomal protein S6 2.06206
COG7 component of oligomeric golgi complex 7 2.06206
TMEM254 transmembrane protein 254 2.04708
ZNF217 zinc finger protein 217 2.04186
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.03191
MTUS2 microtubule associated tumor suppressor candidate 2 2.02995
TAGLN2 transgelin 2 2.02995
TRIM52 tripartite motif containing 52 2.02148
PLS3 plastin 3 2.02031
LRRC1 leucine rich repeat containing 1 2.01916
ADRA2C adrenoceptor alpha 2C 2.01394
FHOD1 formin homology 2 domain containing 1 2.01316
NOL12 nucleolar protein 12 2.00417

decreased expression

Symbol Name Standardized Value
KRT7 keratin 7, type II -2.96702
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.96702
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.96702
PRIMPOL primase and polymerase (DNA-directed) -2.96702
RNFT1 ring finger protein, transmembrane 1 -2.96702
CCDC28B coiled-coil domain containing 28B -2.96702
ZNF324B zinc finger protein 324B -2.96702
FAM53A family with sequence similarity 53, member A -2.96702
ASB14 ankyrin repeat and SOCS box containing 14 -2.96702
ENDOD1 endonuclease domain containing 1 -2.96702
HYKK hydroxylysine kinase -2.96702
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -2.96702
CEPT1 choline/ethanolamine phosphotransferase 1 -2.96702
CATSPER2 cation channel, sperm associated 2 -2.96702
PEPD peptidase D -2.96702
TRUB2 TruB pseudouridine (psi) synthase family member 2 -2.96702
CFAP300 cilia and flagella associated protein 300 -2.96702
CFAP418 cilia and flagella associated protein 418 -2.96702
TTC23L tetratricopeptide repeat domain 23-like -2.96702
MOG myelin oligodendrocyte glycoprotein -2.96702
CEP85 centrosomal protein 85kDa -2.96702
NTSR1 neurotensin receptor 1 (high affinity) -2.96702
LGALS1 lectin, galactoside-binding, soluble, 1 -2.96702
PLEKHA5 pleckstrin homology domain containing, family A member 5 -2.96702
PDHX pyruvate dehydrogenase complex, component X -2.96702
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 -2.96702
SNRK SNF related kinase -2.96702
LIPG lipase, endothelial -2.94266
WASHC1 WASH complex subunit 1 -2.93622
ABI3BP ABI family, member 3 (NESH) binding protein -2.8891
USP50 ubiquitin specific peptidase 50 -2.8891
CPB2 carboxypeptidase B2 (plasma) -2.8891
PMP22 peripheral myelin protein 22 -2.8891
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.8891
CA4 carbonic anhydrase IV -2.8891
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.8891
FLT3LG fms-related tyrosine kinase 3 ligand -2.8891
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic -2.8891
LINC02798 long intergenic non-protein coding RNA 2798 -2.8891
LTBP2 latent transforming growth factor beta binding protein 2 -2.8891
TAS2R30 taste receptor, type 2, member 30 -2.8891
CHRNG cholinergic receptor, nicotinic, gamma (muscle) -2.8891
ZBTB42 zinc finger and BTB domain containing 42 -2.8891
NPSR1 neuropeptide S receptor 1 -2.8891
CC2D2B coiled-coil and C2 domain containing 2B -2.8891
LEKR1 leucine, glutamate and lysine rich 1 -2.8891
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.8891
LIF leukemia inhibitory factor -2.8891
ANKRD53 ankyrin repeat domain 53 -2.8891
CLEC4A C-type lectin domain family 4, member A -2.8891
ANKRD65 ankyrin repeat domain 65 -2.8891
POU3F4 POU class 3 homeobox 4 -2.8891
POC1A POC1 centriolar protein A -2.8891
GBX1 gastrulation brain homeobox 1 -2.8891
S100Z S100 calcium binding protein Z -2.8891
CLIC2 chloride intracellular channel 2 -2.8891
FBN1 fibrillin 1 -2.83105
PALM3 paralemmin 3 -2.7812
IFI27 interferon, alpha-inducible protein 27 -2.7765
THOC7 THO complex 7 -2.77051
LIN7A lin-7 homolog A (C. elegans) -2.76125
AMBRA1 autophagy/beclin-1 regulator 1 -2.76007
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -2.71375
TVP23C trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) -2.69577
RBL1 retinoblastoma-like 1 -2.68153
CDK16 cyclin-dependent kinase 16 -2.66563
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -2.6247
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -2.59414
REC8 REC8 meiotic recombination protein -2.5937
ORAI3 ORAI calcium release-activated calcium modulator 3 -2.5937
NRF1 nuclear respiratory factor 1 -2.54378
KEAP1 kelch-like ECH-associated protein 1 -2.52197
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -2.51288
YEATS4 YEATS domain containing 4 -2.50491
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.46471
PNPLA5 patatin-like phospholipase domain containing 5 -2.45265
CHD1L chromodomain helicase DNA binding protein 1-like -2.4352
APP amyloid beta (A4) precursor protein -2.43057
NBPF15 neuroblastoma breakpoint family, member 15 -2.41052
CPTP ceramide-1-phosphate transfer protein -2.39759
WNT3 wingless-type MMTV integration site family, member 3 -2.39759
BNIPL BCL2/adenovirus E1B 19kD interacting protein like -2.39759
ZEB1 zinc finger E-box binding homeobox 1 -2.39759
RENBP renin binding protein -2.39759
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa -2.38624
TMEM183A transmembrane protein 183A -2.37228
CBR4 carbonyl reductase 4 -2.35272
FAM149A family with sequence similarity 149, member A -2.31427
NPR2 natriuretic peptide receptor 2 -2.27965
DCDC1 doublecortin domain containing 1 -2.27965
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -2.26425
ECHDC2 enoyl CoA hydratase domain containing 2 -2.25819
ATG4C autophagy related 4C, cysteine peptidase -2.22859
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.21324
STIM1 stromal interaction molecule 1 -2.2
STRIP2 striatin interacting protein 2 -2.2
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.19843
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -2.19271
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 -2.18264
ADAM33 ADAM metallopeptidase domain 33 -2.18264
EID2B EP300 interacting inhibitor of differentiation 2B -2.15679
LURAP1 leucine rich adaptor protein 1 -2.13911
GPX7 glutathione peroxidase 7 -2.121
TMEM177 transmembrane protein 177 -2.1159
STRADA STE20-related kinase adaptor alpha -2.10582
FSIP1 fibrous sheath interacting protein 1 -2.10534
MAML2 mastermind-like 2 (Drosophila) -2.0982
IFT27 intraflagellar transport 27 -2.08953
GAB1 GRB2-associated binding protein 1 -2.08839
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.0856
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 -2.0856
RBM42 RNA binding motif protein 42 -2.08183
TEN1 TEN1 CST complex subunit -2.07996
MEAK7 MTOR associated protein, eak-7 homolog -2.06206
SDE2 SDE2 telomere maintenance homolog (S. pombe) -2.05245
HSPA9 heat shock 70kDa protein 9 (mortalin) -2.04844
SNX24 sorting nexin 24 -2.04648
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -2.02995
POM121C POM121 transmembrane nucleoporin C -2.02148
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 -2.02148
ASCC1 activating signal cointegrator 1 complex subunit 1 -2.01916
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -2.01719
LRTM1 leucine-rich repeats and transmembrane domains 1 -2.01719
PROSER2 proline and serine rich 2 -2.01213
NLGN1 neuroligin 1 -2.00588