| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | p21 protein (Cdc42/Rac)-activated kinase 2|The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5062) |
| External Link | https://ncbi.nlm.nih.gov/gene/5062 |
| Similar Terms | |
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499 genes differentially expressed following the PAK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZW10 | zw10 kinetochore protein | 0.0159657 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0150808 |
| THBS1 | thrombospondin 1 | 0.0141193 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0134963 |
| COLEC12 | collectin sub-family member 12 | 0.012315 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0122601 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0121737 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0121396 |
| THBS2 | thrombospondin 2 | 0.0119094 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0118396 |
| STK10 | serine/threonine kinase 10 | 0.0118081 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0116049 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.0115099 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0114931 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0113201 |
| DIPK1A | divergent protein kinase domain 1A | 0.0112768 |
| TRIB2 | tribbles pseudokinase 2 | 0.0111834 |
| NDRG4 | NDRG family member 4 | 0.0110949 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0110664 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.0109317 |
| C7 | complement component 7 | 0.0108458 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0107091 |
| AEBP1 | AE binding protein 1 | 0.01052 |
| LAMB1 | laminin, beta 1 | 0.0104245 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.0102093 |
| COMP | cartilage oligomeric matrix protein | 0.0101494 |
| PLAT | plasminogen activator, tissue | 0.0100925 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00996758 |
| PRKCA | protein kinase C, alpha | 0.00992865 |
| C1RL | complement component 1, r subcomponent-like | 0.00967064 |
| COG7 | component of oligomeric golgi complex 7 | 0.00963982 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00942823 |
| MAL | mal, T-cell differentiation protein | 0.00931717 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00915135 |
| CCNB1 | cyclin B1 | 0.00911852 |
| GATA6 | GATA binding protein 6 | 0.00899692 |
| AUTS2 | autism susceptibility candidate 2 | 0.00896483 |
| COL10A1 | collagen, type X, alpha 1 | 0.00894722 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.0089465 |
| ECM1 | extracellular matrix protein 1 | 0.00887256 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00886349 |
| S100A10 | S100 calcium binding protein A10 | 0.00880178 |
| RAI14 | retinoic acid induced 14 | 0.0087925 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00875508 |
| MMP10 | matrix metallopeptidase 10 | 0.00869155 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00865915 |
| TMEM100 | transmembrane protein 100 | 0.00859321 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00855404 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00852244 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00844581 |
| PLLP | plasmolipin | 0.00843098 |
| CCN2 | cellular communication network factor 2 | 0.00841711 |
| OLFML2A | olfactomedin-like 2A | 0.00836122 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00835018 |
| MEIS1 | Meis homeobox 1 | 0.00834123 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.00829744 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | 0.00815693 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00811697 |
| MSLN | mesothelin | 0.0080513 |
| SDC1 | syndecan 1 | 0.00799542 |
| FBLN5 | fibulin 5 | 0.00796181 |
| CFI | complement factor I | 0.00793931 |
| MIA | melanoma inhibitory activity | 0.00793233 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00785936 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00785193 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00783575 |
| HEATR1 | HEAT repeat containing 1 | 0.00782817 |
| TUBA1A | tubulin, alpha 1a | 0.00781482 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00780896 |
| AMACR | alpha-methylacyl-CoA racemase | 0.00780516 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.0077955 |
| S100A2 | S100 calcium binding protein A2 | 0.00779063 |
| FERMT1 | fermitin family member 1 | 0.00778216 |
| PCTP | phosphatidylcholine transfer protein | 0.00777503 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.0077666 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0077473 |
| GLO1 | glyoxalase I | 0.00770677 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0076864 |
| FXN | frataxin | 0.00765 |
| GAS1 | growth arrest-specific 1 | 0.00764059 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00760095 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00759349 |
| EPYC | epiphycan | 0.00756297 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00753253 |
| SMAD3 | SMAD family member 3 | 0.00752639 |
| PODXL | podocalyxin-like | 0.00750729 |
| VCAN | versican | 0.00750268 |
| SLIT1 | slit homolog 1 (Drosophila) | 0.0074719 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00746353 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00744529 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00741656 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | 0.00740335 |
| TNS3 | tensin 3 | 0.00739953 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.0073947 |
| PTCH1 | patched 1 | 0.00732777 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00732084 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00717662 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00717148 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00711863 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00711836 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00707504 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00704758 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 | 0.00704041 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00703844 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | 0.00702811 |
| DAPK1 | death-associated protein kinase 1 | 0.00699181 |
| LRRC32 | leucine rich repeat containing 32 | 0.00697212 |
| BLMH | bleomycin hydrolase | 0.00695375 |
| TRIM22 | tripartite motif containing 22 | 0.00694647 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00691738 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00691259 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00690951 |
| TFF1 | trefoil factor 1 | 0.00689834 |
| ADA | adenosine deaminase | 0.00688659 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | 0.00688172 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00687234 |
| CHEK1 | checkpoint kinase 1 | 0.00687175 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00686645 |
| CYB561 | cytochrome b561 | 0.00686023 |
| DCHS1 | dachsous cadherin-related 1 | 0.00685856 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00681239 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.0068015 |
| CBFB | core-binding factor, beta subunit | 0.00679728 |
| ASRGL1 | asparaginase like 1 | 0.00675422 |
| LTA4H | leukotriene A4 hydrolase | 0.00673113 |
| PRR5 | proline rich 5 (renal) | 0.00672868 |
| TKTL1 | transketolase-like 1 | 0.00671724 |
| COPS7A | COP9 signalosome subunit 7A | 0.00668924 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0066892 |
| TYRP1 | tyrosinase-related protein 1 | 0.00668391 |
| MXRA7 | matrix-remodelling associated 7 | 0.00668321 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00667701 |
| MUC16 | mucin 16, cell surface associated | 0.0066708 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00664296 |
| MEN1 | multiple endocrine neoplasia I | 0.00663646 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00663254 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00661491 |
| LAMA4 | laminin, alpha 4 | 0.00658839 |
| SYNPO | synaptopodin | 0.00654827 |
| PLP1 | proteolipid protein 1 | 0.00654184 |
| HSPA12A | heat shock 70kDa protein 12A | 0.00652812 |
| TPM2 | tropomyosin 2 (beta) | 0.00652544 |
| SASH3 | SAM and SH3 domain containing 3 | 0.00649683 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00648667 |
| PXDN | peroxidasin | 0.00648323 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00648141 |
| ATP10A | ATPase, class V, type 10A | 0.0064491 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00644818 |
| SMAD6 | SMAD family member 6 | 0.00643271 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00640022 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00639509 |
| F2R | coagulation factor II (thrombin) receptor | 0.00638872 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00638165 |
| NPR3 | natriuretic peptide receptor 3 | 0.00637069 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00636516 |
| SIRT3 | sirtuin 3 | 0.00635158 |
| XPO7 | exportin 7 | 0.00635 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.00632703 |
| ZFHX4 | zinc finger homeobox 4 | 0.00631275 |
| ATP10B | ATPase, class V, type 10B | 0.00627782 |
| NEK9 | NIMA-related kinase 9 | 0.00626371 |
| INSM1 | insulinoma-associated 1 | 0.00625668 |
| HOXA5 | homeobox A5 | 0.00625634 |
| PDZD2 | PDZ domain containing 2 | 0.00624835 |
| MEG3 | maternally expressed 3 (non-protein coding) | 0.00624197 |
| IRF6 | interferon regulatory factor 6 | 0.00623655 |
| KRT13 | keratin 13, type I | 0.00622987 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0061804 |
| CD93 | CD93 molecule | 0.00617486 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00615585 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00615004 |
| NSG1 | neuron specific gene family member 1 | 0.00614228 |
| LEFTY1 | left-right determination factor 1 | 0.00614036 |
| UNG | uracil-DNA glycosylase | 0.00613634 |
| MLPH | melanophilin | 0.00611028 |
| ABLIM1 | actin binding LIM protein 1 | 0.00610251 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00610104 |
| RGS4 | regulator of G-protein signaling 4 | 0.00609839 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00609477 |
| APH1A | APH1A gamma secretase subunit | 0.00608924 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00608613 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00608603 |
| LPXN | leupaxin | 0.00608115 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00604761 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00604283 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00604048 |
| PDGFD | platelet derived growth factor D | 0.0060383 |
| MECOM | MDS1 and EVI1 complex locus | 0.00602948 |
| SFTPC | surfactant protein C | 0.00602543 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00602517 |
| EDNRB | endothelin receptor type B | 0.0060206 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00601334 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00600996 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0059964 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00598543 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00598295 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00597503 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00597452 |
| SEPTIN9 | septin 9 | 0.00597 |
| ADCY7 | adenylate cyclase 7 | 0.00595578 |
| TSPAN8 | tetraspanin 8 | 0.00594846 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00594478 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00593668 |
| EMP1 | epithelial membrane protein 1 | 0.00591746 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00591001 |
| KRT6A | keratin 6A, type II | 0.00590821 |
| FASTKD5 | FAST kinase domains 5 | 0.00590673 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00589536 |
| YLPM1 | YLP motif containing 1 | 0.00589318 |
| LDB2 | LIM domain binding 2 | 0.00588323 |
| EHD3 | EH-domain containing 3 | 0.00587906 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00587631 |
| NDNF | neuron-derived neurotrophic factor | 0.00587387 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | 0.00584426 |
| TSPAN1 | tetraspanin 1 | 0.00584379 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0058382 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | 0.00583469 |
| GPM6B | glycoprotein M6B | 0.00583119 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00582978 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.00582612 |
| SMC6 | structural maintenance of chromosomes 6 | 0.00582067 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00581163 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00578849 |
| ANOS1 | anosmin 1 | 0.00578368 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.0057771 |
| VPREB1 | pre-B lymphocyte 1 | 0.00575106 |
| PALLD | palladin, cytoskeletal associated protein | 0.00574605 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.00573 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.0057151 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00570966 |
| SST | somatostatin | 0.00570109 |
| RCAN1 | regulator of calcineurin 1 | 0.0056886 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00568357 |
| RHOA | ras homolog family member A | 0.00568209 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.00567269 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 0.00566958 |
| LAMC2 | laminin, gamma 2 | 0.00566724 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.00566311 |
| KLF6 | Kruppel-like factor 6 | 0.00565537 |
| TCF21 | transcription factor 21 | 0.00565065 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00564555 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00564466 |
| PEX11B | peroxisomal biogenesis factor 11 beta | 0.0056327 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.005619 |
| CH25H | cholesterol 25-hydroxylase | 0.00561839 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.00560804 |
| MEIS2 | Meis homeobox 2 | 0.00559008 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00558391 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00558294 |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 | 0.00557836 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | -0.0199053 |
| MAGEA3 | melanoma antigen family A3 | -0.0167613 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0142928 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0134759 |
| HHEX | hematopoietically expressed homeobox | -0.013368 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0131042 |
| CLU | clusterin | -0.0128606 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0126859 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.012526 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.0124612 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.0123727 |
| G0S2 | G0/G1 switch 2 | -0.0121555 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.0119899 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.011676 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0111394 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0109975 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0107945 |
| KRT23 | keratin 23, type I | -0.0107922 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0105094 |
| BRD4 | bromodomain containing 4 | -0.0104139 |
| CLC | Charcot-Leyden crystal galectin | -0.0102016 |
| HBD | hemoglobin, delta | -0.0102013 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00994807 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00990426 |
| TSPO | translocator protein (18kDa) | -0.0096879 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00963875 |
| S100A8 | S100 calcium binding protein A8 | -0.00954844 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.00950139 |
| PERP | PERP, TP53 apoptosis effector | -0.00942644 |
| MT1G | metallothionein 1G | -0.00942057 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00933278 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00927715 |
| MT1F | metallothionein 1F | -0.0092695 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00926291 |
| MT1M | metallothionein 1M | -0.00922462 |
| ZNF91 | zinc finger protein 91 | -0.00917672 |
| LY96 | lymphocyte antigen 96 | -0.00913098 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0091191 |
| RAP1GAP | RAP1 GTPase activating protein | -0.00909679 |
| PFDN4 | prefoldin subunit 4 | -0.00907344 |
| CLGN | calmegin | -0.00894364 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.0089133 |
| REEP5 | receptor accessory protein 5 | -0.00885851 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00875196 |
| TMEM106B | transmembrane protein 106B | -0.00859959 |
| NIT1 | nitrilase 1 | -0.00858514 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00855315 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00854734 |
| TMEM87A | transmembrane protein 87A | -0.00853689 |
| TPD52L1 | tumor protein D52-like 1 | -0.00852664 |
| ZNF148 | zinc finger protein 148 | -0.00852139 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00849848 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00841793 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00838538 |
| S100A9 | S100 calcium binding protein A9 | -0.00837858 |
| MT1X | metallothionein 1X | -0.00836864 |
| CST3 | cystatin C | -0.00834623 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00834144 |
| CHI3L2 | chitinase 3-like 2 | -0.00833761 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00829664 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00827625 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00826319 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00822271 |
| AIM2 | absent in melanoma 2 | -0.00819089 |
| TRIB3 | tribbles pseudokinase 3 | -0.00807352 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00798896 |
| RWDD1 | RWD domain containing 1 | -0.00796913 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00796044 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00795688 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00794977 |
| HSPA13 | heat shock protein 70kDa family, member 13 | -0.00789425 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00789132 |
| STC2 | stanniocalcin 2 | -0.00788557 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00777023 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00775983 |
| H1-2 | H1.2 linker histone, cluster member | -0.00775412 |
| BID | BH3 interacting domain death agonist | -0.00771478 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00770313 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | -0.00770142 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00770085 |
| CTSG | cathepsin G | -0.00769968 |
| RAB32 | RAB32, member RAS oncogene family | -0.0076569 |
| NUCB2 | nucleobindin 2 | -0.00765229 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -0.00759674 |
| DUSP5 | dual specificity phosphatase 5 | -0.00758481 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00753255 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00753008 |
| SCAND1 | SCAN domain containing 1 | -0.00752417 |
| TMEM126B | transmembrane protein 126B | -0.00748799 |
| APOD | apolipoprotein D | -0.00744742 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00743085 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00741041 |
| CDC34 | cell division cycle 34 | -0.00740777 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -0.00740264 |
| NUP58 | nucleoporin 58 | -0.00739979 |
| PLPP3 | phospholipid phosphatase 3 | -0.0073934 |
| MT1H | metallothionein 1H | -0.00738724 |
| ELANE | elastase, neutrophil expressed | -0.00738102 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.0073793 |
| BDNF | brain-derived neurotrophic factor | -0.00736171 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00734423 |
| CTSL | cathepsin L | -0.00734021 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00732849 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0073163 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00729067 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00727827 |
| LST1 | leukocyte specific transcript 1 | -0.00726565 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00721724 |
| CAV2 | caveolin 2 | -0.00715338 |
| ACYP2 | acylphosphatase 2, muscle type | -0.00713476 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00712537 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.0071236 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00711277 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0071089 |
| FGL2 | fibrinogen-like 2 | -0.00710378 |
| S100A12 | S100 calcium binding protein A12 | -0.00707849 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00707833 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00704289 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00702256 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0070224 |
| FZD6 | frizzled class receptor 6 | -0.00702213 |
| CLDN1 | claudin 1 | -0.00700686 |
| MICU2 | mitochondrial calcium uptake 2 | -0.00700621 |
| ZNF43 | zinc finger protein 43 | -0.00699059 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -0.00698919 |
| SNX13 | sorting nexin 13 | -0.006978 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.00696191 |
| CPE | carboxypeptidase E | -0.00696058 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00694923 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00692867 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00691828 |
| POP7 | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) | -0.00684862 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00684827 |
| ZNF430 | zinc finger protein 430 | -0.00683148 |
| MT1E | metallothionein 1E | -0.00682661 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00682271 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00680625 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00679275 |
| RPS17 | ribosomal protein S17 | -0.00678819 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00678285 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00676976 |
| WTAP | Wilms tumor 1 associated protein | -0.0067641 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00676244 |
| SNAP23 | synaptosomal-associated protein, 23kDa | -0.00674704 |
| CSTA | cystatin A (stefin A) | -0.00673793 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00673122 |
| GLRX2 | glutaredoxin 2 | -0.00672468 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic | -0.00671429 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00671378 |
| BSG | basigin (Ok blood group) | -0.00669884 |
| BLVRB | biliverdin reductase B | -0.00669863 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00669041 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00667938 |
| TMEM14B | transmembrane protein 14B | -0.00667909 |
| FPR1 | formyl peptide receptor 1 | -0.00667892 |
| MMP9 | matrix metallopeptidase 9 | -0.006666 |
| BCL2L1 | BCL2-like 1 | -0.00663993 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00663872 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00663736 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.00662786 |
| ATP5IF1 | ATP synthase inhibitory factor subunit 1 | -0.0066247 |
| PF4 | platelet factor 4 | -0.00661487 |
| SDF4 | stromal cell derived factor 4 | -0.00661452 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00661112 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00659702 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00659569 |
| PELO | pelota homolog (Drosophila) | -0.00659034 |
| TEX30 | testis expressed 30 | -0.00658334 |
| YAP1 | Yes-associated protein 1 | -0.00658051 |
| RNF115 | ring finger protein 115 | -0.00657361 |
| BBX | bobby sox homolog (Drosophila) | -0.00657163 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0065676 |
| MAOA | monoamine oxidase A | -0.0065562 |
| GOLGA8A | golgin A8 family, member A | -0.00655422 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00653062 |
| MED28 | mediator complex subunit 28 | -0.00652716 |
| PDGFC | platelet derived growth factor C | -0.00652334 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00652241 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00650726 |
| RAP2A | RAP2A, member of RAS oncogene family | -0.00650378 |
| WDR45 | WD repeat domain 45 | -0.00648591 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00646847 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00646515 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0064557 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00645427 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00644832 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00644235 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.0064201 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00641863 |
| WDR13 | WD repeat domain 13 | -0.00640833 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00639653 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00639593 |
| USP15 | ubiquitin specific peptidase 15 | -0.00637703 |
| DCLK1 | doublecortin-like kinase 1 | -0.00636189 |
| SEC61G | Sec61 gamma subunit | -0.00635772 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00635449 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 | -0.00634015 |
| ORC1 | origin recognition complex, subunit 1 | -0.00633974 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.00633849 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00631499 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00630874 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | -0.00629759 |
| MGAM | maltase-glucoamylase | -0.00628639 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.0062373 |
| ECI1 | enoyl-CoA delta isomerase 1 | -0.00623481 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00623273 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 | -0.00622826 |
| CHN1 | chimerin 1 | -0.00618854 |
| ZNF580 | zinc finger protein 580 | -0.00618845 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00615605 |
| HOXA10 | homeobox A10 | -0.00613935 |
| HSPB11 | heat shock protein family B (small), member 11 | -0.00612991 |
| GLA | galactosidase, alpha | -0.00612168 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00611931 |
| MAGEA12 | melanoma antigen family A12 | -0.0061167 |
| KYAT3 | kynurenine aminotransferase 3 | -0.00611441 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00611376 |
| METTL5 | methyltransferase like 5 | -0.00608723 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00608519 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00606533 |
| GRN | granulin | -0.00606085 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.00606057 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00605755 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.0060546 |
| LTF | lactotransferrin | -0.00605397 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00605153 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00603531 |
| HNMT | histamine N-methyltransferase | -0.00603226 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.00602953 |
| ORC4 | origin recognition complex, subunit 4 | -0.00602602 |
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | -0.00600911 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00600879 |
| TMEM45A | transmembrane protein 45A | -0.00596949 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0059568 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0059385 |
| BBIP1 | BBSome interacting protein 1 | -0.00593646 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00592639 |
| PLIN2 | perilipin 2 | -0.00591476 |
| GMPR | guanosine monophosphate reductase | -0.00591191 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00591003 |
| FASTKD3 | FAST kinase domains 3 | -0.00590697 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00589461 |
| ABHD3 | abhydrolase domain containing 3 | -0.00589118 |
| ATP5MG | ATP synthase membrane subunit g | -0.00588132 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.0058701 |
| GMFG | glia maturation factor, gamma | -0.00585351 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00585021 |
| CTSH | cathepsin H | -0.00583597 |
| PSPC1 | paraspeckle component 1 | -0.0058339 |
