PAK2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description p21 protein (Cdc42/Rac)-activated kinase 2|The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5062)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_PAK2
Similar Terms
Downloads & Tools

Genes

28 co-expressed genes for PAK2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CD53 CD53 molecule
CNOT8 CCR4-NOT transcription complex, subunit 8
DOCK2 dedicator of cytokinesis 2
ELF4 E74-like factor 4 (ets domain transcription factor)
FMNL1 formin-like 1
GMFG glia maturation factor, gamma
HCLS1 hematopoietic cell-specific Lyn substrate 1
MYD88 myeloid differentiation primary response 88
OSBPL8 oxysterol binding protein-like 8
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PHF21A PHD finger protein 21A
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SELL selectin L
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TYK2 tyrosine kinase 2
USP3 ubiquitin specific peptidase 3
VAV1 vav 1 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
ZCCHC6 zinc finger, CCHC domain containing 6