| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | peptidylglycine alpha-amidating monooxygenase|This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5066) |
| External Link | https://ncbi.nlm.nih.gov/gene/5066 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PAM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.0265855 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0182591 |
| ITM2A | integral membrane protein 2A | 0.0161237 |
| CDCA4 | cell division cycle associated 4 | 0.0158627 |
| MAP7 | microtubule-associated protein 7 | 0.0153245 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0146195 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0141271 |
| NRN1 | neuritin 1 | 0.0125201 |
| CST7 | cystatin F (leukocystatin) | 0.012492 |
| CD200 | CD200 molecule | 0.0118137 |
| RPS5 | ribosomal protein S5 | 0.011279 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.0112388 |
| CD53 | CD53 molecule | 0.0111537 |
| MPO | myeloperoxidase | 0.0110786 |
| PCNA | proliferating cell nuclear antigen | 0.0110778 |
| H2AX | H2A.X variant histone | 0.0109028 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0108185 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0108021 |
| FYB1 | FYN binding protein 1 | 0.0106832 |
| SIRT3 | sirtuin 3 | 0.0106401 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0105983 |
| METRN | meteorin, glial cell differentiation regulator | 0.0105614 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.0105492 |
| LTF | lactotransferrin | 0.0104951 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0104518 |
| CAMP | cathelicidin antimicrobial peptide | 0.0104224 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.0102482 |
| AIF1 | allograft inflammatory factor 1 | 0.0101643 |
| HOPX | HOP homeobox | 0.0100754 |
| ZNF589 | zinc finger protein 589 | 0.0100467 |
| SELL | selectin L | 0.0100224 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00990321 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 0.00985086 |
| TADA2A | transcriptional adaptor 2A | 0.00980428 |
| CD8A | CD8a molecule | 0.00975165 |
| MMP9 | matrix metallopeptidase 9 | 0.00933729 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.0093292 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00932441 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00931915 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00922942 |
| PRF1 | perforin 1 (pore forming protein) | 0.00921231 |
| LYZ | lysozyme | 0.00912711 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00907986 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00900829 |
| CD48 | CD48 molecule | 0.00888756 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00884915 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00884477 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00880775 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.0087804 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00876381 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00871213 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00863891 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00855107 |
| CD99 | CD99 molecule | 0.00854984 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00848852 |
| SLA | Src-like-adaptor | 0.00848157 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00846037 |
| AGR2 | anterior gradient 2 | 0.00844193 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00844111 |
| CD14 | CD14 molecule | 0.00842274 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00837303 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.0083687 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0083432 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00832952 |
| GPR171 | G protein-coupled receptor 171 | 0.00827465 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.00825119 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00817928 |
| ESD | esterase D | 0.00817784 |
| ABHD10 | abhydrolase domain containing 10 | 0.00817228 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00816466 |
| OLFM4 | olfactomedin 4 | 0.00814583 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.0081445 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00812726 |
| CCND2 | cyclin D2 | 0.00810434 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00804658 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00803155 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00800197 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00798629 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00794193 |
| THYN1 | thymocyte nuclear protein 1 | 0.00791295 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00789615 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.00789073 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00788344 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.0078813 |
| DHFR | dihydrofolate reductase | 0.00787039 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00786886 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0078688 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.00786121 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00784572 |
| CTSG | cathepsin G | 0.0078266 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00779318 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0077595 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00775721 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.00775267 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00769136 |
| GPI | glucose-6-phosphate isomerase | 0.00762351 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00757956 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00757602 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00757269 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00752985 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.00751809 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00751728 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00748387 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.007474 |
| CCNA2 | cyclin A2 | 0.00746177 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00745856 |
| NKG7 | natural killer cell granule protein 7 | 0.00744788 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00744113 |
| COMMD10 | COMM domain containing 10 | 0.00741643 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00739748 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 0.00738855 |
| PCP4 | Purkinje cell protein 4 | 0.00734436 |
| CSTA | cystatin A (stefin A) | 0.00733127 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00732962 |
| FGL2 | fibrinogen-like 2 | 0.00732392 |
| SASH3 | SAM and SH3 domain containing 3 | 0.00731541 |
| IL2RG | interleukin 2 receptor, gamma | 0.00731324 |
| CRYL1 | crystallin, lambda 1 | 0.00730616 |
| ELANE | elastase, neutrophil expressed | 0.0072963 |
| IL2RB | interleukin 2 receptor, beta | 0.00727315 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00726733 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00726332 |
| SNX5 | sorting nexin 5 | 0.00726156 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00725518 |
| LMNB2 | lamin B2 | 0.00725037 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00724336 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0072209 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.00718958 |
| JAM3 | junctional adhesion molecule 3 | 0.00718019 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00715511 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00715418 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.00714133 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00714069 |
| NID2 | nidogen 2 (osteonidogen) | 0.00711899 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00711848 |
| WDR61 | WD repeat domain 61 | 0.0071053 |
| RCAN2 | regulator of calcineurin 2 | 0.00710441 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00709313 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | 0.00708551 |
| C1QA | complement component 1, q subcomponent, A chain | 0.0070716 |
| CPNE1 | copine I | 0.00705162 |
| S100B | S100 calcium binding protein B | 0.00704039 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.0069968 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00699174 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00698846 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00694092 |
| CRIP2 | cysteine-rich protein 2 | 0.00689601 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00688582 |
| ARG1 | arginase 1 | 0.0068679 |
| EMX2 | empty spiracles homeobox 2 | 0.00686718 |
| MGP | matrix Gla protein | 0.00685858 |
| CPQ | carboxypeptidase Q | 0.00684524 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00683607 |
| RHOH | ras homolog family member H | 0.00683604 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00682915 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.00682225 |
| HMGB3 | high mobility group box 3 | 0.0068151 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.00680899 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00679696 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00677638 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00677181 |
| ASPA | aspartoacylase | 0.00676727 |
| ITK | IL2-inducible T-cell kinase | 0.00675545 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00673635 |
| PNN | pinin, desmosome associated protein | 0.0067272 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | 0.0067198 |
| TRMT5 | tRNA methyltransferase 5 | 0.00671425 |
| SFN | stratifin | 0.00671342 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.00670952 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00669917 |
| RGS1 | regulator of G-protein signaling 1 | 0.00669784 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00669432 |
| C3AR1 | complement component 3a receptor 1 | 0.00668179 |
| PAX6 | paired box 6 | 0.00667986 |
| PEG3 | paternally expressed 3 | 0.00667435 |
| KIF20A | kinesin family member 20A | 0.00663351 |
| MYO5C | myosin VC | 0.00659901 |
| GPATCH8 | G patch domain containing 8 | 0.00659894 |
| VSNL1 | visinin-like 1 | 0.00659491 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.00658034 |
| CD2 | CD2 molecule | 0.00658008 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00657985 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00657921 |
| FGF13 | fibroblast growth factor 13 | 0.00657603 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.00657271 |
| PRKCB | protein kinase C, beta | 0.00656418 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00653602 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0065333 |
| PGD | phosphogluconate dehydrogenase | 0.00653198 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.0065298 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00652848 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00651362 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00650749 |
| CA2 | carbonic anhydrase II | 0.00650542 |
| AHCY | adenosylhomocysteinase | 0.00650333 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00650007 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.00649504 |
| HMBS | hydroxymethylbilane synthase | 0.00649264 |
| HOXC6 | homeobox C6 | 0.00648778 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00646053 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00645023 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00644275 |
| CLDN8 | claudin 8 | 0.00643754 |
| COX5A | cytochrome c oxidase subunit Va | 0.00642705 |
| UNG | uracil-DNA glycosylase | 0.006426 |
| IL16 | interleukin 16 | 0.00640139 |
| CLCA1 | chloride channel accessory 1 | 0.00638537 |
| TOX | thymocyte selection-associated high mobility group box | 0.00637775 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00637375 |
| EI24 | etoposide induced 2.4 | 0.00636918 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00634252 |
| CEP43 | centrosomal protein 43 | 0.00633515 |
| HOXB2 | homeobox B2 | 0.00632309 |
| PER2 | period circadian clock 2 | 0.00632087 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.00631755 |
| MRPS27 | mitochondrial ribosomal protein S27 | 0.00630791 |
| MST1 | macrophage stimulating 1 | 0.00630748 |
| RANBP1 | RAN binding protein 1 | 0.0062894 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00628613 |
| ANXA6 | annexin A6 | 0.00628169 |
| NANOG | Nanog homeobox | 0.00628075 |
| FNBP1 | formin binding protein 1 | 0.00627478 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | 0.00627193 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.00626919 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00626058 |
| TXNL4A | thioredoxin-like 4A | 0.00624661 |
| PER3 | period circadian clock 3 | 0.00622648 |
| SNX17 | sorting nexin 17 | 0.00622434 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 0.00622011 |
| COG2 | component of oligomeric golgi complex 2 | 0.00618604 |
| RNF130 | ring finger protein 130 | 0.00618566 |
| MGAM | maltase-glucoamylase | 0.00617274 |
| PRR5L | proline rich 5 like | 0.00616827 |
| CHN2 | chimerin 2 | 0.00614079 |
| STAT4 | signal transducer and activator of transcription 4 | 0.00613793 |
| IFT52 | intraflagellar transport 52 | 0.00612426 |
| PLCL2 | phospholipase C-like 2 | 0.00610886 |
| LY86 | lymphocyte antigen 86 | 0.00610829 |
| CDC20 | cell division cycle 20 | 0.00608924 |
| CD4 | CD4 molecule | 0.00608629 |
| MCM4 | minichromosome maintenance complex component 4 | 0.00608324 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 | 0.00608236 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00607002 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00606292 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00605606 |
| WWOX | WW domain containing oxidoreductase | 0.00605464 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00605004 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00604648 |
| PGAP2 | post-GPI attachment to proteins 2 | 0.00604297 |
| RPS25 | ribosomal protein S25 | 0.00601276 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ATF3 | activating transcription factor 3 | -0.0217103 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0200271 |
| MX1 | MX dynamin-like GTPase 1 | -0.0184913 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.018042 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0177579 |
| EGR1 | early growth response 1 | -0.0166189 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0162747 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0159301 |
| XIC | X chromosome inactivation center | -0.0153658 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0152433 |
| RTN2 | reticulon 2 | -0.0151244 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0148569 |
| CRYAB | crystallin, alpha B | -0.0148262 |
| CFB | complement factor B | -0.014763 |
| TTN | titin | -0.0145952 |
| MX2 | MX dynamin-like GTPase 2 | -0.013832 |
| HIST1H2BK | histone cluster 1, H2bk | -0.0137737 |
| MYBPC1 | myosin binding protein C, slow type | -0.0137463 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0135778 |
| GDF15 | growth differentiation factor 15 | -0.0135634 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0134899 |
| COQ8A | coenzyme Q8A | -0.0133952 |
| IFI44 | interferon-induced protein 44 | -0.0133012 |
| HMOX1 | heme oxygenase 1 | -0.0131651 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0130628 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0127936 |
| TNNC1 | troponin C type 1 (slow) | -0.0127727 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0126584 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0126389 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0125859 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.0125799 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0125225 |
| KRT23 | keratin 23, type I | -0.0124591 |
| RND3 | Rho family GTPase 3 | -0.0123901 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.0122132 |
| H1-2 | H1.2 linker histone, cluster member | -0.0121358 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.012099 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0120987 |
| CKM | creatine kinase, muscle | -0.0120472 |
| TNNC2 | troponin C type 2 (fast) | -0.0119064 |
| IFI44L | interferon-induced protein 44-like | -0.0118756 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0118263 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.0117954 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0117891 |
| KLHL41 | kelch-like family member 41 | -0.0117044 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.0116131 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0115637 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0114807 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0114001 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0113468 |
| JUNB | jun B proto-oncogene | -0.0113293 |
| IL7R | interleukin 7 receptor | -0.0113248 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0111585 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.0110782 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0109676 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.0109443 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0109139 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.0108737 |
| MB | myoglobin | -0.0108304 |
| TXNDC9 | thioredoxin domain containing 9 | -0.01082 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0107102 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.0107064 |
| FOSL2 | FOS-like antigen 2 | -0.0107022 |
| IRF7 | interferon regulatory factor 7 | -0.0106746 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0106243 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0105064 |
| SLN | sarcolipin | -0.0104535 |
| EMP2 | epithelial membrane protein 2 | -0.0103409 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.01034 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0103333 |
| TUFT1 | tuftelin 1 | -0.0103164 |
| IRS2 | insulin receptor substrate 2 | -0.0103157 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0102989 |
| NAV2 | neuron navigator 2 | -0.0102312 |
| MAOA | monoamine oxidase A | -0.0102034 |
| PFKM | phosphofructokinase, muscle | -0.0101941 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0101753 |
| VEGFA | vascular endothelial growth factor A | -0.0100617 |
| AMOTL2 | angiomotin like 2 | -0.0100612 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.0100464 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0100407 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0100254 |
| HIST1H2BH | histone cluster 1, H2bh | -0.00987367 |
| DUSP5 | dual specificity phosphatase 5 | -0.00983985 |
| PRAME | preferentially expressed antigen in melanoma | -0.00968812 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00968572 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00968552 |
| MCL1 | myeloid cell leukemia 1 | -0.0096806 |
| MYBPC2 | myosin binding protein C, fast type | -0.00965798 |
| MGLL | monoglyceride lipase | -0.00957863 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00954719 |
| MT1M | metallothionein 1M | -0.00953777 |
| KRT13 | keratin 13, type I | -0.00951876 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00951795 |
| EGR3 | early growth response 3 | -0.00951462 |
| EMP1 | epithelial membrane protein 1 | -0.00945779 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00943611 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00923989 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00920307 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00913866 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00902994 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00902295 |
| TRIB1 | tribbles pseudokinase 1 | -0.00901936 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00900599 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00900311 |
| SIK1 | salt-inducible kinase 1 | -0.00896925 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00896576 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00896392 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00895929 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00886123 |
| HDAC9 | histone deacetylase 9 | -0.00885011 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0088323 |
| ARG2 | arginase 2 | -0.00878794 |
| TBX3 | T-box 3 | -0.00877327 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00874598 |
| MMP7 | matrix metallopeptidase 7 | -0.00872252 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0086367 |
| MIR22HG | MIR22 host gene | -0.00861357 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00859056 |
| WWC1 | WW and C2 domain containing 1 | -0.00858349 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00857912 |
| XAF1 | XIAP associated factor 1 | -0.00851148 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00850781 |
| TPM3 | tropomyosin 3 | -0.00847029 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00846693 |
| MYO1C | myosin IC | -0.00846047 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00844609 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00841926 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00840894 |
| MEF2C | myocyte enhancer factor 2C | -0.00840814 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00839112 |
| PPL | periplakin | -0.00832427 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00831186 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00830477 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00829772 |
| MYOT | myotilin | -0.00829201 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00825788 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00819714 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00819621 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.0081604 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0081584 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00815342 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00812691 |
| NXN | nucleoredoxin | -0.00808885 |
| PLK2 | polo-like kinase 2 | -0.00807558 |
| BTG2 | BTG family, member 2 | -0.00805196 |
| TGFA | transforming growth factor, alpha | -0.00803724 |
| HAT1 | histone acetyltransferase 1 | -0.00799863 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0079678 |
| LEPROT | leptin receptor overlapping transcript | -0.00796611 |
| KRT15 | keratin 15, type I | -0.00796505 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.00793549 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00792729 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00792046 |
| CD9 | CD9 molecule | -0.00788831 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00786068 |
| SHROOM2 | shroom family member 2 | -0.00785497 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00785241 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00783357 |
| LOX | lysyl oxidase | -0.00781953 |
| IL1B | interleukin 1, beta | -0.00779989 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.0077836 |
| MYOZ2 | myozenin 2 | -0.00776265 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00775694 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.00775312 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00773854 |
| RRAD | Ras-related associated with diabetes | -0.00772851 |
| FADS3 | fatty acid desaturase 3 | -0.00769299 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00769275 |
| STC2 | stanniocalcin 2 | -0.00769208 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.00768751 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00767206 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00763769 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00762979 |
| DUOX2 | dual oxidase 2 | -0.00762404 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00760323 |
| PENK | proenkephalin | -0.00758826 |
| ASS1 | argininosuccinate synthase 1 | -0.00758215 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0075699 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00755116 |
| CLTB | clathrin, light chain B | -0.00751356 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00751345 |
| CLDN1 | claudin 1 | -0.00750531 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.00748453 |
| MITF | microphthalmia-associated transcription factor | -0.00748069 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | -0.0074725 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.00746818 |
| WBP5 | WW domain binding protein 5 | -0.00744543 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0074438 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00743857 |
| GLRX | glutaredoxin (thioltransferase) | -0.00743539 |
| IGF1R | insulin-like growth factor 1 receptor | -0.00743273 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00741992 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00740889 |
| ENO3 | enolase 3 (beta, muscle) | -0.0074013 |
| PLA1A | phospholipase A1 member A | -0.00736977 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.00736487 |
| EPHA2 | EPH receptor A2 | -0.00735755 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.00735276 |
| RAB6A | RAB6A, member RAS oncogene family | -0.00733872 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00732905 |
| IL6 | interleukin 6 | -0.00729135 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00728799 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00727653 |
| KLHL24 | kelch-like family member 24 | -0.00725748 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.00723955 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.0072319 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00720894 |
| TYMP | thymidine phosphorylase | -0.00719992 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00719505 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00719279 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00717634 |
| PSCA | prostate stem cell antigen | -0.00715687 |
| KLK10 | kallikrein-related peptidase 10 | -0.00715609 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00714911 |
| CD44 | CD44 molecule (Indian blood group) | -0.00714178 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00713059 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00713005 |
| USP18 | ubiquitin specific peptidase 18 | -0.00712926 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00712806 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.00710343 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00710185 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00708346 |
| CAST | calpastatin | -0.00707961 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00707498 |
| BMP2 | bone morphogenetic protein 2 | -0.00706719 |
| TRIM38 | tripartite motif containing 38 | -0.00703225 |
| FHL2 | four and a half LIM domains 2 | -0.00702561 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00701679 |
| PRSS23 | protease, serine, 23 | -0.00699185 |
| PF4 | platelet factor 4 | -0.00697116 |
| SQSTM1 | sequestosome 1 | -0.00696947 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.00694284 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.00692044 |
| ITGAV | integrin, alpha V | -0.00691356 |
| E2F2 | E2F transcription factor 2 | -0.00688571 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.00687213 |
| GRN | granulin | -0.00684448 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00682576 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00682339 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00680687 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | -0.00680155 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.00679576 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00679309 |
| PRR7 | proline rich 7 (synaptic) | -0.00679019 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.00678464 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00677908 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00675987 |
| SMPX | small muscle protein, X-linked | -0.00675869 |
