PAPPA2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description pappalysin 2|This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 60676)
External Link http://www.ncbi.nlm.nih.gov/gene/60676
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Genes

9 interacting proteins for PAPPA2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATF7IP activating transcription factor 7 interacting protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
SMAD4 SMAD family member 4
ZNF512B zinc finger protein 512B