PAPSS2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description 3'-phosphoadenosine 5'-phosphosulfate synthase 2|Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9060)
External Link https://ncbi.nlm.nih.gov/gene/9060
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Genes

499 genes differentially expressed following the PAPSS2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ISG15 ISG15 ubiquitin-like modifier 0.0172467
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0159714
AQP3 aquaporin 3 (Gill blood group) 0.0145011
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.014374
IFI27 interferon, alpha-inducible protein 27 0.0143731
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0135033
EMX2 empty spiracles homeobox 2 0.0131537
IFI44L interferon-induced protein 44-like 0.0131467
TNNT1 troponin T type 1 (skeletal, slow) 0.0130244
CD58 CD58 molecule 0.0127702
MX1 MX dynamin-like GTPase 1 0.0117982
RAI14 retinoic acid induced 14 0.0117958
IFI6 interferon, alpha-inducible protein 6 0.0116527
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0110231
PODXL podocalyxin-like 0.0108195
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0104432
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0103164
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.0102548
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.0100975
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00980031
IFI44 interferon-induced protein 44 0.00972077
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00968711
HMGA1 high mobility group AT-hook 1 0.00966253
LAMP3 lysosomal-associated membrane protein 3 0.00959591
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00958359
BAMBI BMP and activin membrane-bound inhibitor 0.0094715
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00946631
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00942782
IRF7 interferon regulatory factor 7 0.00942774
PDZK1IP1 PDZK1 interacting protein 1 0.00941845
S100A7 S100 calcium binding protein A7 0.00935468
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00918619
TACSTD2 tumor-associated calcium signal transducer 2 0.00906007
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00903275
INAVA innate immunity activator 0.00902917
SIK1 salt-inducible kinase 1 0.00902852
IFITM1 interferon induced transmembrane protein 1 0.00898917
EAF2 ELL associated factor 2 0.00895515
ARMCX1 armadillo repeat containing, X-linked 1 0.00895419
ECM1 extracellular matrix protein 1 0.00886846
THBS1 thrombospondin 1 0.00885976
MMP10 matrix metallopeptidase 10 0.00883355
RTN2 reticulon 2 0.00874686
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00873549
DACH1 dachshund family transcription factor 1 0.00866325
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.00863794
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00861028
TFPI2 tissue factor pathway inhibitor 2 0.00857578
ISG20 interferon stimulated exonuclease gene 20kDa 0.00851025
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00850194
CEMIP cell migration inducing protein, hyaluronan binding 0.00842085
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00839673
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00829023
DLK1 delta-like 1 homolog (Drosophila) 0.00827059
MDK midkine (neurite growth-promoting factor 2) 0.00822968
NEU1 sialidase 1 (lysosomal sialidase) 0.00809666
MX2 MX dynamin-like GTPase 2 0.00807747
TOX3 TOX high mobility group box family member 3 0.0080701
IER5 immediate early response 5 0.00806474
MVP major vault protein 0.00803766
KLF6 Kruppel-like factor 6 0.00803414
MEF2C myocyte enhancer factor 2C 0.00797781
EIF5A eukaryotic translation initiation factor 5A 0.00795077
TNNC1 troponin C type 1 (slow) 0.00794827
RNASET2 ribonuclease T2 0.00791148
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00788084
HSPA1A heat shock 70kDa protein 1A 0.00781592
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00778462
IL6R interleukin 6 receptor 0.00773749
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00760506
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.00760227
PADI2 peptidyl arginine deiminase, type II 0.00757799
BAG3 BCL2-associated athanogene 3 0.00756866
ACE2 angiotensin I converting enzyme 2 0.00753848
PLAT plasminogen activator, tissue 0.00748484
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00747484
MAST4 microtubule associated serine/threonine kinase family member 4 0.00747232
STX3 syntaxin 3 0.00742924
PKM pyruvate kinase, muscle 0.00742161
AGRN agrin 0.00740334
TXNDC9 thioredoxin domain containing 9 0.00738165
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.00737438
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00737126
FST follistatin 0.00735233
PYCARD PYD and CARD domain containing 0.00734872
MAL mal, T-cell differentiation protein 0.00730923
COG7 component of oligomeric golgi complex 7 0.00724286
GUSBP3 glucuronidase, beta pseudogene 3 0.00723457
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00723122
TSPAN1 tetraspanin 1 0.00718476
RNF167 ring finger protein 167 0.0071845
TNNI1 troponin I type 1 (skeletal, slow) 0.00714125
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00712347
TEX10 testis expressed 10 0.00711345
NPEPL1 aminopeptidase-like 1 0.00708523
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00704093
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00702387
NXN nucleoredoxin 0.00702127
ACTA1 actin, alpha 1, skeletal muscle 0.00699482
CYBA cytochrome b-245, alpha polypeptide 0.00696772
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00695084
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00694773
GUCY2C guanylate cyclase 2C 0.00694749
PSAP prosaposin 0.00688633
CHMP5 charged multivesicular body protein 5 0.00686868
SLC44A4 solute carrier family 44, member 4 0.00683942
HDAC9 histone deacetylase 9 0.0068121
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.006812
RFC2 replication factor C (activator 1) 2, 40kDa 0.00680747
GPX1 glutathione peroxidase 1 0.00678213
C9ORF16 chromosome 9 open reading frame 16 0.00674371
HIST3H2A histone cluster 3, H2a 0.00673147
SELENOW selenoprotein W 0.00671776
TNIP1 TNFAIP3 interacting protein 1 0.00669594
LGALS13 lectin, galactoside-binding, soluble, 13 0.00667263
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00667183
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00666002
USP18 ubiquitin specific peptidase 18 0.00665414
RHOBTB1 Rho-related BTB domain containing 1 0.00665262
MISP mitotic spindle positioning 0.00664076
TMEM14B transmembrane protein 14B 0.0066397
SMAD3 SMAD family member 3 0.00662428
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.0066117
IFIH1 interferon induced with helicase C domain 1 0.0065832
RGS10 regulator of G-protein signaling 10 0.00658211
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.00658147
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.00657491
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 0.00656226
MED6 mediator complex subunit 6 0.00654738
MSMB microseminoprotein, beta- 0.0065223
TUBB2A tubulin, beta 2A class IIa 0.00651864
HOMER3 homer scaffolding protein 3 0.00650579
GYPC glycophorin C (Gerbich blood group) 0.00650426
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00648924
NPAS2 neuronal PAS domain protein 2 0.00648173
ACP5 acid phosphatase 5, tartrate resistant 0.0064805
EZR ezrin 0.006477
VAMP8 vesicle-associated membrane protein 8 0.0064679
GRB7 growth factor receptor-bound protein 7 0.00642335
BIRC2 baculoviral IAP repeat containing 2 0.00641698
CRYM crystallin, mu 0.00639057
NUP210 nucleoporin 210kDa 0.00638758
UGCG UDP-glucose ceramide glucosyltransferase 0.00637444
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00636903
RSAD2 radical S-adenosyl methionine domain containing 2 0.00634482
COG2 component of oligomeric golgi complex 2 0.00634433
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00632743
ITM2C integral membrane protein 2C 0.00632371
TNNC2 troponin C type 2 (fast) 0.00629507
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00629171
WBP5 WW domain binding protein 5 0.00629016
DGKZ diacylglycerol kinase, zeta 0.00626819
LGALS3 lectin, galactoside-binding, soluble, 3 0.00626547
PTHLH parathyroid hormone-like hormone 0.00626148
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00625668
AKAP8L A kinase (PRKA) anchor protein 8-like 0.00621474
LGALS2 lectin, galactoside-binding, soluble, 2 0.00618074
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00615898
FOSL2 FOS-like antigen 2 0.00610706
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00610256
PLK2 polo-like kinase 2 0.0061003
FZD10 frizzled class receptor 10 0.00609807
FABP7 fatty acid binding protein 7, brain 0.00609436
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00609243
WIF1 WNT inhibitory factor 1 0.00608239
DUSP5 dual specificity phosphatase 5 0.00607383
ZDHHC11 zinc finger, DHHC-type containing 11 0.00606742
RND1 Rho family GTPase 1 0.00605363
LGALS9 lectin, galactoside-binding, soluble, 9 0.00604707
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00603852
CAPN3 calpain 3, (p94) 0.0060245
ATF4 activating transcription factor 4 0.0060216
C8ORF4 chromosome 8 open reading frame 4 0.00602069
COL2A1 collagen, type II, alpha 1 0.00600064
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00597859
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00597538
SH2B2 SH2B adaptor protein 2 0.00596718
NVL nuclear VCP-like 0.00595024
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.00594695
SDC1 syndecan 1 0.00593581
KRT20 keratin 20, type I 0.00593255
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00592697
KRT13 keratin 13, type I 0.00592295
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00591597
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae) 0.00590895
S100A14 S100 calcium binding protein A14 0.00589598
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00588009
GPR137B G protein-coupled receptor 137B 0.0058671
CLTB clathrin, light chain B 0.00586627
RRAD Ras-related associated with diabetes 0.00586403
TRIM16 tripartite motif containing 16 0.0058619
QPRT quinolinate phosphoribosyltransferase 0.00584498
TRIM38 tripartite motif containing 38 0.0058403
BAX BCL2-associated X protein 0.00583682
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.0058204
TSPAN12 tetraspanin 12 0.00582018
ZNF551 zinc finger protein 551 0.00581867
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.00580168
SMPX small muscle protein, X-linked 0.00580081
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00577685
SCAND1 SCAN domain containing 1 0.00577052
FGFR1 fibroblast growth factor receptor 1 0.00574486
GJA1 gap junction protein, alpha 1, 43kDa 0.00571044
COPS7A COP9 signalosome subunit 7A 0.00570078
LGALS1 lectin, galactoside-binding, soluble, 1 0.00567452
CTSH cathepsin H 0.00562279
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00562055
TPM2 tropomyosin 2 (beta) 0.00561353
SCGB2A1 secretoglobin, family 2A, member 1 0.00560456
ATXN1 ataxin 1 0.00559493
TPI1 triosephosphate isomerase 1 0.00558987
ARMC9 armadillo repeat containing 9 0.00558788
TUFT1 tuftelin 1 0.00558215
OXA1L oxidase (cytochrome c) assembly 1-like 0.00557366
SMS spermine synthase 0.0055602
CD9 CD9 molecule 0.00554349
LRP4 low density lipoprotein receptor-related protein 4 0.00552625
MRPL23 mitochondrial ribosomal protein L23 0.00551665
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 0.00549874
CXCL14 chemokine (C-X-C motif) ligand 14 0.00549688
YPEL5 yippee-like 5 (Drosophila) 0.00549284
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00549003
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.00548749
GUK1 guanylate kinase 1 0.00548045
MYLIP myosin regulatory light chain interacting protein 0.00545832
IFI35 interferon-induced protein 35 0.00543508
SELE selectin E 0.00543385
NARF nuclear prelamin A recognition factor 0.00541871
FOLR1 folate receptor 1 (adult) 0.00541521
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.00540465
LYPD1 LY6/PLAUR domain containing 1 0.00540444
DENND2B DENN domain containing 2B 0.00540185
CKM creatine kinase, muscle 0.00538025
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.00537018
AOC1 amine oxidase, copper containing 1 0.00536845
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00536641
MELK maternal embryonic leucine zipper kinase 0.00535753
HAL histidine ammonia-lyase 0.0053531
FXYD3 FXYD domain containing ion transport regulator 3 0.00535113
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00535037
TMEM160 transmembrane protein 160 0.00534497
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00533894
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.00531639
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00530464
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00530463
CDK18 cyclin-dependent kinase 18 0.00530172
TADA2A transcriptional adaptor 2A 0.00530171
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00529925
GRN granulin 0.00528901
CD59 CD59 molecule, complement regulatory protein 0.00528388

decreased expression

Symbol Name Standardized Value
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0178642
SEPP1 selenoprotein P, plasma, 1 -0.0151465
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.0134651
ALB albumin -0.0124845
CD163 CD163 molecule -0.012335
GOLM1 golgi membrane protein 1 -0.0119447
CD14 CD14 molecule -0.011579
IGFBP5 insulin-like growth factor binding protein 5 -0.0113661
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0113194
MMP9 matrix metallopeptidase 9 -0.0113094
GNAS GNAS complex locus -0.0111302
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.011007
ALOX5 arachidonate 5-lipoxygenase -0.0109831
F13A1 coagulation factor XIII, A1 polypeptide -0.0109615
C1QB complement component 1, q subcomponent, B chain -0.0107813
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0106928
CCL4 chemokine (C-C motif) ligand 4 -0.0105492
CPE carboxypeptidase E -0.0105161
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.010471
RTN1 reticulon 1 -0.0104162
ABAT 4-aminobutyrate aminotransferase -0.0102897
MAGEA3 melanoma antigen family A3 -0.0102604
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.0102041
C1QA complement component 1, q subcomponent, A chain -0.0101473
C1R complement component 1, r subcomponent -0.0100168
TNC tenascin C -0.0099965
CCL19 chemokine (C-C motif) ligand 19 -0.00962581
MMP2 matrix metallopeptidase 2 -0.00955565
HEATR1 HEAT repeat containing 1 -0.00954562
MGP matrix Gla protein -0.00931931
LTF lactotransferrin -0.00929022
NIT1 nitrilase 1 -0.00925343
G0S2 G0/G1 switch 2 -0.00918024
ANXA3 annexin A3 -0.00899575
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00894544
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00893269
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -0.00892308
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00890791
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.0088971
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.00889605
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00889325
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.00888661
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00873598
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00870328
BTBD3 BTB (POZ) domain containing 3 -0.00866263
ANO1 anoctamin 1, calcium activated chloride channel -0.00855289
RUFY3 RUN and FYVE domain containing 3 -0.00853595
CD320 CD320 molecule -0.00850578
METTL7A methyltransferase like 7A -0.00847945
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00845039
CP ceruloplasmin (ferroxidase) -0.00842301
VSIG4 V-set and immunoglobulin domain containing 4 -0.0084035
COL6A1 collagen, type VI, alpha 1 -0.00833411
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00831398
FMO3 flavin containing monooxygenase 3 -0.00830531
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00826866
APMAP adipocyte plasma membrane associated protein -0.00826525
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00825368
APOA2 apolipoprotein A-II -0.00821671
DSP desmoplakin -0.00818439
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00816086
PSD3 pleckstrin and Sec7 domain containing 3 -0.00809889
F3 coagulation factor III (thromboplastin, tissue factor) -0.00806489
DPYSL3 dihydropyrimidinase-like 3 -0.00802881
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00802273
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -0.00802236
MPPED2 metallophosphoesterase domain containing 2 -0.00801032
ANPEP alanyl (membrane) aminopeptidase -0.00800319
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00796425
CPT1A carnitine palmitoyltransferase 1A (liver) -0.00795081
GAL galanin/GMAP prepropeptide -0.00794345
C1S complement component 1, s subcomponent -0.0079393
FAM172A family with sequence similarity 172, member A -0.00793543
OLFM4 olfactomedin 4 -0.00791548
CHPT1 choline phosphotransferase 1 -0.00790139
CDO1 cysteine dioxygenase type 1 -0.00786638
COL6A2 collagen, type VI, alpha 2 -0.0078593
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 -0.00785258
MT1M metallothionein 1M -0.00784131
FPR1 formyl peptide receptor 1 -0.00779155
ZBTB16 zinc finger and BTB domain containing 16 -0.00776888
LEPR leptin receptor -0.00774715
FGG fibrinogen gamma chain -0.00774466
APOB apolipoprotein B -0.00773615
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00772731
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.00771792
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00767672
XYLT1 xylosyltransferase I -0.00767401
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00761048
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00759815
SPARCL1 SPARC-like 1 (hevin) -0.00758501
LEF1 lymphoid enhancer-binding factor 1 -0.0075512
TMSB15A thymosin beta 15a -0.00751331
ADIRF adipogenesis regulatory factor -0.00743875
SC5D sterol-C5-desaturase -0.00743427
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00743268
CSRP1 cysteine and glycine-rich protein 1 -0.0073758
S100A4 S100 calcium binding protein A4 -0.00732661
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00730866
PRKD3 protein kinase D3 -0.00729733
LECT2 leukocyte cell-derived chemotaxin 2 -0.00729305
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.00728734
C3AR1 complement component 3a receptor 1 -0.00728673
GYG1 glycogenin 1 -0.00726882
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -0.0072637
HHEX hematopoietically expressed homeobox -0.00721118
TIMP1 TIMP metallopeptidase inhibitor 1 -0.0072068
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00720355
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00714728
AHSG alpha-2-HS-glycoprotein -0.00714315
PCDH9 protocadherin 9 -0.00714272
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -0.00712609
ORM1 orosomucoid 1 -0.0071177
FUCA1 fucosidase, alpha-L- 1, tissue -0.00710825
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00708642
ASPN asporin -0.00708201
MAGEA12 melanoma antigen family A12 -0.00706544
ELP1 elongator acetyltransferase complex subunit 1 -0.00704895
SDC2 syndecan 2 -0.0070351
SYBU syntabulin (syntaxin-interacting) -0.00703508
ASPH aspartate beta-hydroxylase -0.00703246
TMEM176B transmembrane protein 176B -0.00701608
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00701417
UBL3 ubiquitin-like 3 -0.00701079
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00699987
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00699042
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00697322
SUB1 SUB1 homolog (S. cerevisiae) -0.00692422
SOBP sine oculis binding protein homolog (Drosophila) -0.006899
SLBP stem-loop binding protein -0.00685994
LAMA4 laminin, alpha 4 -0.00685301
IGFBP1 insulin-like growth factor binding protein 1 -0.00684584
PCOLCE procollagen C-endopeptidase enhancer -0.00679472
SOX11 SRY (sex determining region Y)-box 11 -0.00677279
H1-0 H1.0 linker histone -0.00676487
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.0067413
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.0067391
SIRT3 sirtuin 3 -0.00671835
CENPE centromere protein E, 312kDa -0.00671681
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0066995
ABHD3 abhydrolase domain containing 3 -0.00669338
FGA fibrinogen alpha chain -0.00667328
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00663174
MFAP5 microfibrillar associated protein 5 -0.00662808
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00661937
GLUD1 glutamate dehydrogenase 1 -0.0066155
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00660299
CENPC centromere protein C -0.00658166
PLIN1 perilipin 1 -0.00657049
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -0.0065428
TTR transthyretin -0.00654044
MAK16 MAK16 homolog (S. cerevisiae) -0.00652577
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00652409
AQP9 aquaporin 9 -0.00651646
PCDH17 protocadherin 17 -0.00651248
CD209 CD209 molecule -0.00651235
KIF20A kinesin family member 20A -0.0064986
APOA1 apolipoprotein A-I -0.00646383
SIDT2 SID1 transmembrane family, member 2 -0.00646136
ZNF281 zinc finger protein 281 -0.00645873
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00644945
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00643241
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00643094
PPARG peroxisome proliferator-activated receptor gamma -0.00639576
PRF1 perforin 1 (pore forming protein) -0.00638269
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -0.00638129
NKX3-1 NK3 homeobox 1 -0.00636259
CADPS2 Ca++-dependent secretion activator 2 -0.00636083
RTN3 reticulon 3 -0.00635344
GZMK granzyme K (granzyme 3; tryptase II) -0.00635253
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.00634376
RAD23B RAD23 homolog B (S. cerevisiae) -0.00632347
SORD sorbitol dehydrogenase -0.00630922
ESYT1 extended synaptotagmin-like protein 1 -0.0062823
SLC46A3 solute carrier family 46, member 3 -0.00627943
PON1 paraoxonase 1 -0.00627892
PDE8B phosphodiesterase 8B -0.00625045
GSTM3 glutathione S-transferase mu 3 (brain) -0.00623669
TPD52L1 tumor protein D52-like 1 -0.00618878
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -0.00618419
SPATA5L1 spermatogenesis associated 5-like 1 -0.00618378
SLIT2 slit homolog 2 (Drosophila) -0.00618041
PMP22 peripheral myelin protein 22 -0.006178
AFM afamin -0.00617129
CSAD cysteine sulfinic acid decarboxylase -0.00616985
F5 coagulation factor V (proaccelerin, labile factor) -0.00616165
RPIA ribose 5-phosphate isomerase A -0.00614672
TWIST1 twist family bHLH transcription factor 1 -0.00613866
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.0061385
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00613779
PPIC peptidylprolyl isomerase C (cyclophilin C) -0.00613583
HMGB1 high mobility group box 1 -0.00613135
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00612658
FGB fibrinogen beta chain -0.00611678
CFI complement factor I -0.00611229
UBE4A ubiquitination factor E4A -0.00609344
DEFA4 defensin, alpha 4, corticostatin -0.00609337
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.0060891
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00608653
STC2 stanniocalcin 2 -0.00608078
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -0.00607569
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00607034
DIXDC1 DIX domain containing 1 -0.00606839
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0060669
HPX hemopexin -0.00605835
PIP prolactin-induced protein -0.00605756
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00605456
LYZ lysozyme -0.00604453
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -0.00603471
AUTS2 autism susceptibility candidate 2 -0.00602846
CCDC92 coiled-coil domain containing 92 -0.00602286
A2M alpha-2-macroglobulin -0.00599049
INSR insulin receptor -0.00598352
RNF130 ring finger protein 130 -0.00597223
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00596185
ARG1 arginase 1 -0.00594818
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00593844
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -0.00592971
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -0.0059195
POSTN periostin, osteoblast specific factor -0.0059162
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00591589
EMP3 epithelial membrane protein 3 -0.00590005
WIPF1 WAS/WASL interacting protein family, member 1 -0.00588675
NUP107 nucleoporin 107kDa -0.00586208
NOTCH2 notch 2 -0.00585616
SNX10 sorting nexin 10 -0.00585104
GAS1 growth arrest-specific 1 -0.00583581
TARP TCR gamma alternate reading frame protein -0.00580796
C6 complement component 6 -0.00576078
WDR19 WD repeat domain 19 -0.00573936
CPD carboxypeptidase D -0.00573846
TBC1D16 TBC1 domain family, member 16 -0.00572571
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00570857
SYT11 synaptotagmin XI -0.00569738
KANK2 KN motif and ankyrin repeat domains 2 -0.00568981
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0056878
CLU clusterin -0.00568594
VCAM1 vascular cell adhesion molecule 1 -0.00568415
GRB14 growth factor receptor-bound protein 14 -0.00567794
ISL1 ISL LIM homeobox 1 -0.00567611
TFR2 transferrin receptor 2 -0.00565647
GNMT glycine N-methyltransferase -0.00565394
FOXO1 forkhead box O1 -0.00565272
KLF9 Kruppel-like factor 9 -0.00564622
WWC3 WWC family member 3 -0.00564284
TRPS1 trichorhinophalangeal syndrome I -0.00564284
STEAP3 STEAP family member 3, metalloreductase -0.00564268
CRP C-reactive protein, pentraxin-related -0.00562974
CPQ carboxypeptidase Q -0.00562352