| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | poly (ADP-ribose) polymerase 1|This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 142) |
| External Link | https://ncbi.nlm.nih.gov/gene/142 |
| Similar Terms | |
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498 genes differentially expressed following the PARP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00880105 |
| S100P | S100 calcium binding protein P | 0.00805621 |
| PDGFC | platelet derived growth factor C | 0.00785958 |
| COL3A1 | collagen, type III, alpha 1 | 0.0076331 |
| GATA6 | GATA binding protein 6 | 0.00680327 |
| CALML5 | calmodulin-like 5 | 0.00678055 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00663071 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00656621 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00636827 |
| VCAN | versican | 0.00635929 |
| MSLN | mesothelin | 0.00634903 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00634249 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00633974 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00617521 |
| MANSC1 | MANSC domain containing 1 | 0.00615645 |
| RTN2 | reticulon 2 | 0.00610049 |
| MUC16 | mucin 16, cell surface associated | 0.00604953 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00600839 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00595441 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00595084 |
| TSPAN12 | tetraspanin 12 | 0.00593297 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00590589 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00586342 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00578149 |
| KLK8 | kallikrein-related peptidase 8 | 0.00575382 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00571808 |
| ZNF217 | zinc finger protein 217 | 0.00571027 |
| SPON2 | spondin 2, extracellular matrix protein | 0.0056675 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.00563419 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00561155 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00559372 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00554619 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.00549804 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00548503 |
| PLIN2 | perilipin 2 | 0.00546734 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.00544514 |
| PLBD1 | phospholipase B domain containing 1 | 0.00542803 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 | 0.00539179 |
| KAZN | kazrin, periplakin interacting protein | 0.00534742 |
| DEFB1 | defensin, beta 1 | 0.00533994 |
| KRT23 | keratin 23, type I | 0.00526838 |
| CD302 | CD302 molecule | 0.00526558 |
| PRDX2 | peroxiredoxin 2 | 0.00521991 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00520702 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00519128 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00512064 |
| NID1 | nidogen 1 | 0.00507388 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00503549 |
| HAL | histidine ammonia-lyase | 0.00500372 |
| OXTR | oxytocin receptor | 0.00500319 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00497065 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00495697 |
| MAGEA3 | melanoma antigen family A3 | 0.00491609 |
| CAV2 | caveolin 2 | 0.00490484 |
| TRHDE | thyrotropin-releasing hormone degrading enzyme | 0.00489823 |
| ASRGL1 | asparaginase like 1 | 0.00489197 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00488063 |
| CYBB | cytochrome b-245, beta polypeptide | 0.0048791 |
| KRT1 | keratin 1, type II | 0.00487499 |
| ASPN | asporin | 0.00485134 |
| TJP2 | tight junction protein 2 | 0.00483852 |
| CLC | Charcot-Leyden crystal galectin | 0.00482521 |
| WASHC4 | WASH complex subunit 4 | 0.00482354 |
| MEIS2 | Meis homeobox 2 | 0.0048224 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00480269 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00477619 |
| HNMT | histamine N-methyltransferase | 0.00473388 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00470468 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00469965 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00468844 |
| MEIS1 | Meis homeobox 1 | 0.00465225 |
| CENPE | centromere protein E, 312kDa | 0.0046508 |
| LRRC17 | leucine rich repeat containing 17 | 0.00464526 |
| COG2 | component of oligomeric golgi complex 2 | 0.00463669 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00462312 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00460755 |
| DMXL2 | Dmx-like 2 | 0.00459677 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00459583 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00457148 |
| ZW10 | zw10 kinetochore protein | 0.00455482 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00453654 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00452901 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00452401 |
| COL5A2 | collagen, type V, alpha 2 | 0.00450222 |
| HCRTR1 | hypocretin (orexin) receptor 1 | 0.00447606 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00447484 |
| RXRA | retinoid X receptor, alpha | 0.00447406 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00446466 |
| KRT2 | keratin 2, type II | 0.00445609 |
| FAM13A | family with sequence similarity 13, member A | 0.00444093 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.00443928 |
| ANXA4 | annexin A4 | 0.00443902 |
| CST6 | cystatin E/M | 0.00441804 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00440979 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00439234 |
| RPIA | ribose 5-phosphate isomerase A | 0.00438799 |
| LAMA4 | laminin, alpha 4 | 0.00438796 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00435469 |
| ANXA3 | annexin A3 | 0.00435158 |
| FJX1 | four jointed box 1 (Drosophila) | 0.00435073 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00432838 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00432377 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00432123 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00431789 |
| NELL1 | NEL-like 1 (chicken) | 0.00430837 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00430585 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00429041 |
| ATXN1 | ataxin 1 | 0.00428403 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.0042726 |
| CLDN10 | claudin 10 | 0.00426511 |
| FILIP1L | filamin A interacting protein 1-like | 0.00426397 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00424713 |
| C5AR1 | complement component 5a receptor 1 | 0.00424257 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00423581 |
| RGCC | regulator of cell cycle | 0.00422934 |
| ANXA6 | annexin A6 | 0.00422886 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00422498 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | 0.00419275 |
| DSG1 | desmoglein 1 | 0.00419089 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00417298 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00416237 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.00415329 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00414741 |
| SVIL | supervillin | 0.00414676 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00414122 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 0.00413911 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.00412128 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.00410632 |
| LAMA5 | laminin, alpha 5 | 0.00408551 |
| HIST3H2A | histone cluster 3, H2a | 0.00407995 |
| CFI | complement factor I | 0.00407677 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00407121 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00407108 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0040655 |
| MSRB1 | methionine sulfoxide reductase B1 | 0.00406535 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0040617 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0040497 |
| EMX2 | empty spiracles homeobox 2 | 0.0040333 |
| CDC45 | cell division cycle 45 | 0.00403205 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00403079 |
| FGL2 | fibrinogen-like 2 | 0.00402795 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00402525 |
| C7 | complement component 7 | 0.00401019 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00397517 |
| CHKB | choline kinase beta | 0.00397208 |
| AIF1 | allograft inflammatory factor 1 | 0.00393488 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0039325 |
| KLK7 | kallikrein-related peptidase 7 | 0.00391786 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0039105 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00390533 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00388527 |
| LST1 | leukocyte specific transcript 1 | 0.00388141 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00387423 |
| VLDLR | very low density lipoprotein receptor | 0.00385103 |
| NFE2 | nuclear factor, erythroid 2 | 0.00385102 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00384999 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00384676 |
| CD14 | CD14 molecule | 0.00383673 |
| CD99 | CD99 molecule | 0.00383433 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00383253 |
| ARFIP1 | ADP-ribosylation factor interacting protein 1 | 0.0038289 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.0038236 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00381574 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.00381426 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00380759 |
| KLK5 | kallikrein-related peptidase 5 | 0.00377704 |
| H2AX | H2A.X variant histone | 0.00377589 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00377134 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0037695 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00376591 |
| MMP11 | matrix metallopeptidase 11 | 0.00373179 |
| RAI2 | retinoic acid induced 2 | 0.00372724 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 0.0037245 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00372257 |
| RGS5 | regulator of G-protein signaling 5 | 0.00371905 |
| MXRA5 | matrix-remodelling associated 5 | 0.00371554 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.00371318 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.0037085 |
| TLR4 | toll-like receptor 4 | 0.00370284 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00370204 |
| MAGEA12 | melanoma antigen family A12 | 0.00368819 |
| KLK6 | kallikrein-related peptidase 6 | 0.00368657 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00368166 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00367373 |
| PLN | phospholamban | 0.00367173 |
| S100A12 | S100 calcium binding protein A12 | 0.0036526 |
| ANKRD6 | ankyrin repeat domain 6 | 0.00364926 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00363074 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.00360969 |
| CD300A | CD300a molecule | 0.00359354 |
| TRMT5 | tRNA methyltransferase 5 | 0.00359338 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00359306 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00359295 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00357984 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00357688 |
| HEPH | hephaestin | 0.00357139 |
| SORT1 | sortilin 1 | 0.00356418 |
| CRY1 | cryptochrome circadian clock 1 | 0.00355504 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00354612 |
| KLHDC3 | kelch domain containing 3 | 0.0035454 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00353134 |
| TYMS | thymidylate synthetase | 0.00351719 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00351578 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00350471 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00348309 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | 0.00348012 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00347446 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 | 0.00346201 |
| MPO | myeloperoxidase | 0.00345811 |
| EPHA4 | EPH receptor A4 | 0.00345729 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.00342783 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00342685 |
| TBC1D12 | TBC1 domain family, member 12 | 0.00342213 |
| PLXDC1 | plexin domain containing 1 | 0.0034219 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00342024 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00341433 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0034007 |
| SLC2A4RG | SLC2A4 regulator | 0.00339503 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00339046 |
| STXBP2 | syntaxin binding protein 2 | 0.0033902 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.00339006 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00338234 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0033814 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00337542 |
| CLIC3 | chloride intracellular channel 3 | 0.0033647 |
| STK3 | serine/threonine kinase 3 | 0.00335617 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0033501 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.00334882 |
| FBXO9 | F-box protein 9 | 0.00334694 |
| DSC1 | desmocollin 1 | 0.00333789 |
| NRCAM | neuronal cell adhesion molecule | 0.00333574 |
| PTEN | phosphatase and tensin homolog | 0.00333104 |
| GAS6 | growth arrest-specific 6 | 0.00332286 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00331722 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00330898 |
| HPF1 | histone PARylation factor 1 | 0.00329767 |
| ARG1 | arginase 1 | 0.00329189 |
| CTSV | cathepsin V | 0.00328005 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | 0.00327017 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.00326751 |
| ZNF83 | zinc finger protein 83 | 0.00326684 |
| RORA | RAR-related orphan receptor A | 0.00326097 |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.00325925 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00325493 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00325405 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00325043 |
| TLE4 | transducin-like enhancer of split 4 | 0.0032484 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) | 0.00323992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.0145742 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00904876 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00866428 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00851571 |
| CD9 | CD9 molecule | -0.00806778 |
| KRT5 | keratin 5, type II | -0.00804054 |
| PAX5 | paired box 5 | -0.00757718 |
| AIM2 | absent in melanoma 2 | -0.00723782 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00710051 |
| KRT15 | keratin 15, type I | -0.00687781 |
| MMP12 | matrix metallopeptidase 12 | -0.00678062 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00649968 |
| GLUL | glutamate-ammonia ligase | -0.00648745 |
| SPRR3 | small proline-rich protein 3 | -0.00637038 |
| RGS13 | regulator of G-protein signaling 13 | -0.00630104 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00616984 |
| PCP4 | Purkinje cell protein 4 | -0.00610774 |
| CD79B | CD79b molecule, immunoglobulin-associated beta | -0.00607418 |
| SIRT3 | sirtuin 3 | -0.00601226 |
| FADS3 | fatty acid desaturase 3 | -0.00597904 |
| S100A2 | S100 calcium binding protein A2 | -0.00592502 |
| CD19 | CD19 molecule | -0.00592312 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | -0.00589871 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00589523 |
| PRDX1 | peroxiredoxin 1 | -0.00585801 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0058573 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00580975 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00580429 |
| TFF1 | trefoil factor 1 | -0.0057807 |
| KRT14 | keratin 14, type I | -0.00576381 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00572644 |
| SIK1 | salt-inducible kinase 1 | -0.00569641 |
| ORM1 | orosomucoid 1 | -0.00568201 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00564896 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00562338 |
| CALCA | calcitonin-related polypeptide alpha | -0.00557579 |
| MALL | mal, T-cell differentiation protein-like | -0.00555566 |
| FN1 | fibronectin 1 | -0.00552491 |
| SYT11 | synaptotagmin XI | -0.00544943 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.00544832 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00540655 |
| STK39 | serine threonine kinase 39 | -0.00539132 |
| PCDH9 | protocadherin 9 | -0.00537174 |
| MT1E | metallothionein 1E | -0.00536468 |
| AREG | amphiregulin | -0.00535054 |
| MT1G | metallothionein 1G | -0.00534883 |
| TP63 | tumor protein p63 | -0.005338 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00533102 |
| CD38 | CD38 molecule | -0.00527583 |
| FGG | fibrinogen gamma chain | -0.00526787 |
| VPREB3 | pre-B lymphocyte 3 | -0.0052307 |
| CTSB | cathepsin B | -0.00521627 |
| GPX1 | glutathione peroxidase 1 | -0.005181 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | -0.00517996 |
| PLP1 | proteolipid protein 1 | -0.00512924 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00509316 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00507323 |
| KRT13 | keratin 13, type I | -0.00503938 |
| ALB | albumin | -0.00503777 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.0050372 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00503652 |
| CA12 | carbonic anhydrase XII | -0.00495007 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | -0.00493381 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00492778 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00491572 |
| GPM6B | glycoprotein M6B | -0.00488956 |
| DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | -0.00486204 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00483711 |
| MCL1 | myeloid cell leukemia 1 | -0.00482806 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00479315 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00478948 |
| CD72 | CD72 molecule | -0.00476683 |
| RTN1 | reticulon 1 | -0.004765 |
| NEFM | neurofilament, medium polypeptide | -0.0047553 |
| CES1 | carboxylesterase 1 | -0.00472949 |
| WIF1 | WNT inhibitory factor 1 | -0.00469538 |
| NEFH | neurofilament, heavy polypeptide | -0.00468868 |
| SYT1 | synaptotagmin I | -0.00467839 |
| PEG10 | paternally expressed 10 | -0.00467452 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00467168 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00464362 |
| MT1F | metallothionein 1F | -0.00460786 |
| MT1H | metallothionein 1H | -0.00460525 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00459847 |
| TCL1A | T-cell leukemia/lymphoma 1A | -0.00458479 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00457075 |
| MT1X | metallothionein 1X | -0.00456038 |
| ZNF532 | zinc finger protein 532 | -0.00455477 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00454763 |
| BTG2 | BTG family, member 2 | -0.00453083 |
| CLCA4 | chloride channel accessory 4 | -0.00451531 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00447827 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00447525 |
| STMN2 | stathmin 2 | -0.00446936 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00439564 |
| FGB | fibrinogen beta chain | -0.00436607 |
| FGA | fibrinogen alpha chain | -0.00435829 |
| AUTS2 | autism susceptibility candidate 2 | -0.00435514 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00434337 |
| C4BPA | complement component 4 binding protein, alpha | -0.00433957 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | -0.00433442 |
| LPIN1 | lipin 1 | -0.00432191 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00430985 |
| DSG3 | desmoglein 3 | -0.00430063 |
| NDRG1 | N-myc downstream regulated 1 | -0.00429941 |
| IRAG2 | inositol 1,4,5-triphosphate receptor associated 2 | -0.00429927 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00427711 |
| OLFM1 | olfactomedin 1 | -0.00425431 |
| CFB | complement factor B | -0.00423461 |
| TUBA4A | tubulin, alpha 4a | -0.00418451 |
| JUNB | jun B proto-oncogene | -0.00415951 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.0041504 |
| ARG2 | arginase 2 | -0.00414679 |
| TPD52L1 | tumor protein D52-like 1 | -0.00409449 |
| ABHD4 | abhydrolase domain containing 4 | -0.00408759 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00408327 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00407702 |
| DUSP2 | dual specificity phosphatase 2 | -0.00406213 |
| KRT6A | keratin 6A, type II | -0.00405911 |
| TNC | tenascin C | -0.00404492 |
| KRT17 | keratin 17, type I | -0.00404059 |
| GPX2 | glutathione peroxidase 2 | -0.0040335 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00401775 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00401716 |
| CD177 | CD177 molecule | -0.00401095 |
| BCAS4 | breast carcinoma amplified sequence 4 | -0.00400099 |
| SPRR1B | small proline-rich protein 1B | -0.00400053 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.00399254 |
| GPC3 | glypican 3 | -0.00398155 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00393779 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00393342 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00392923 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00392779 |
| ODC1 | ornithine decarboxylase 1 | -0.00392268 |
| CRYM | crystallin, mu | -0.00392208 |
| NPY | neuropeptide Y | -0.00392075 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00391106 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00390847 |
| KYNU | kynureninase | -0.00390044 |
| RBM34 | RNA binding motif protein 34 | -0.00389266 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0038913 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -0.00388705 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.00388705 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00386929 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.00386238 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.00385794 |
| IFNGR1 | interferon gamma receptor 1 | -0.00385644 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00385531 |
| CEP170 | centrosomal protein 170kDa | -0.00384702 |
| TAC1 | tachykinin, precursor 1 | -0.0038361 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00382906 |
| KRT6B | keratin 6B, type II | -0.00381998 |
| OLFML2A | olfactomedin-like 2A | -0.00381965 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.00380737 |
| ARTN | artemin | -0.00380019 |
| FABP1 | fatty acid binding protein 1, liver | -0.00379652 |
| HEATR1 | HEAT repeat containing 1 | -0.00379121 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.0037895 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00378585 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00377236 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -0.00374544 |
| KIF1A | kinesin family member 1A | -0.00374286 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00373642 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.00373448 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00373064 |
| SPRR2B | small proline-rich protein 2B | -0.00372427 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00372066 |
| VSNL1 | visinin-like 1 | -0.00371595 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00371576 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00370905 |
| CH25H | cholesterol 25-hydroxylase | -0.00370077 |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | -0.00369916 |
| SELE | selectin E | -0.00369579 |
| ECM1 | extracellular matrix protein 1 | -0.00369377 |
| IGSF1 | immunoglobulin superfamily, member 1 | -0.00368693 |
| PASK | PAS domain containing serine/threonine kinase | -0.0036764 |
| PTN | pleiotrophin | -0.00367367 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00366962 |
| TPD52 | tumor protein D52 | -0.00366288 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00365547 |
| IL6ST | interleukin 6 signal transducer | -0.00365232 |
| FLT3 | fms-related tyrosine kinase 3 | -0.00365127 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00364623 |
| CD52 | CD52 molecule | -0.00363143 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00363052 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00362949 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00362595 |
| ZNF281 | zinc finger protein 281 | -0.00361558 |
| FCMR | Fc fragment of IgM receptor | -0.00361088 |
| EAF2 | ELL associated factor 2 | -0.00360622 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.0036059 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00359868 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00359789 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00358147 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.00357082 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00356358 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00355695 |
| CLDN5 | claudin 5 | -0.00353794 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.00353373 |
| MME | membrane metallo-endopeptidase | -0.00353152 |
| TMEM243 | transmembrane protein 243, mitochondrial | -0.00352689 |
| KLHL24 | kelch-like family member 24 | -0.00351968 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | -0.00351537 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.00351221 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00351134 |
| PON3 | paraoxonase 3 | -0.0035098 |
| SPRR1A | small proline-rich protein 1A | -0.00350822 |
| SC5D | sterol-C5-desaturase | -0.00348357 |
| IRF4 | interferon regulatory factor 4 | -0.00348247 |
| MALT1 | MALT1 paracaspase | -0.00348071 |
| GLA | galactosidase, alpha | -0.00346731 |
| SCG5 | secretogranin V | -0.00346407 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | -0.00345748 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00345733 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -0.00345397 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.00345154 |
| BLNK | B-cell linker | -0.00343489 |
| PLA2G2D | phospholipase A2, group IID | -0.0034148 |
| APOC3 | apolipoprotein C-III | -0.00341163 |
| BTG3 | BTG family, member 3 | -0.00340517 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00340306 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00339622 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00339489 |
| WDR48 | WD repeat domain 48 | -0.00338788 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0033803 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00337998 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00337758 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00337113 |
| C1ORF95 | chromosome 1 open reading frame 95 | -0.00337109 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00335916 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | -0.00335772 |
| HPD | 4-hydroxyphenylpyruvate dioxygenase | -0.00335688 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.00335157 |
| LAMB3 | laminin, beta 3 | -0.00333593 |
| OGA | O-GlcNAcase | -0.00333189 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00332656 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00331334 |
| MT2A | metallothionein 2A | -0.00331298 |
| PTHLH | parathyroid hormone-like hormone | -0.00330443 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00329978 |
| HOXD1 | homeobox D1 | -0.00329954 |
| CDC123 | cell division cycle 123 | -0.00329153 |
| MXRA7 | matrix-remodelling associated 7 | -0.00328217 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | -0.00328192 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00326794 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.00326217 |
| HIP1 | huntingtin interacting protein 1 | -0.00326111 |
| REEP5 | receptor accessory protein 5 | -0.00325976 |
| TMEM14A | transmembrane protein 14A | -0.00324649 |
| CPB2 | carboxypeptidase B2 (plasma) | -0.00324539 |
