| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | PAS domain containing serine/threonine kinase|This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 23178) |
| External Link | https://ncbi.nlm.nih.gov/gene/23178 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PASK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.017048 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0162597 |
| WT1 | Wilms tumor 1 | 0.0150239 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.0146498 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0141435 |
| CSTA | cystatin A (stefin A) | 0.0137974 |
| MSMB | microseminoprotein, beta- | 0.0135266 |
| CCND2 | cyclin D2 | 0.0127697 |
| TSPYL5 | TSPY-like 5 | 0.0125574 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0124888 |
| EMX2 | empty spiracles homeobox 2 | 0.0124756 |
| JAG1 | jagged 1 | 0.0124202 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.0117951 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0115786 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0114902 |
| DIPK1A | divergent protein kinase domain 1A | 0.0114712 |
| EPCAM | epithelial cell adhesion molecule | 0.011254 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.011119 |
| PCP4 | Purkinje cell protein 4 | 0.0110137 |
| DPEP1 | dipeptidase 1 (renal) | 0.0108793 |
| PLN | phospholamban | 0.010446 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0104402 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.0103512 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.0103152 |
| ANXA3 | annexin A3 | 0.0100958 |
| TPM2 | tropomyosin 2 (beta) | 0.00998752 |
| CLIC5 | chloride intracellular channel 5 | 0.00985997 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00981165 |
| MGAM | maltase-glucoamylase | 0.00963467 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00955067 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00954337 |
| LY96 | lymphocyte antigen 96 | 0.0094714 |
| LYPD1 | LY6/PLAUR domain containing 1 | 0.00937081 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00934529 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00918993 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00918478 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00915067 |
| SLC38A6 | solute carrier family 38, member 6 | 0.00911048 |
| GMPR | guanosine monophosphate reductase | 0.00892765 |
| S100A8 | S100 calcium binding protein A8 | 0.00885395 |
| INAVA | innate immunity activator | 0.00880517 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00879318 |
| MFAP5 | microfibrillar associated protein 5 | 0.0087644 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00873737 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00870782 |
| IPO13 | importin 13 | 0.00868458 |
| PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.00866921 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00856343 |
| CD38 | CD38 molecule | 0.00854746 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | 0.00854061 |
| MME | membrane metallo-endopeptidase | 0.0084614 |
| BTG3 | BTG family, member 3 | 0.00842518 |
| ADD3 | adducin 3 (gamma) | 0.00842492 |
| FOLR1 | folate receptor 1 (adult) | 0.00832158 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00830884 |
| KRT19 | keratin 19, type I | 0.00828678 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00827168 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.00825482 |
| NOX4 | NADPH oxidase 4 | 0.00822261 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00819503 |
| CALB1 | calbindin 1, 28kDa | 0.00819366 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0081495 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0081428 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00811723 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00811671 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00809164 |
| B9D1 | B9 protein domain 1 | 0.00804283 |
| CD58 | CD58 molecule | 0.00803658 |
| GATA6 | GATA binding protein 6 | 0.00800869 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00798939 |
| INHBA | inhibin, beta A | 0.00794257 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00793499 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00786082 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00785921 |
| MAGED1 | melanoma antigen family D1 | 0.00784519 |
| HSPA2 | heat shock 70kDa protein 2 | 0.007817 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.0078133 |
| EAF2 | ELL associated factor 2 | 0.00778497 |
| COMP | cartilage oligomeric matrix protein | 0.00777157 |
| MSLN | mesothelin | 0.00766611 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.00764636 |
| TSPOAP1 | TSPO associated protein 1 | 0.00760029 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.00757675 |
| GSPT2 | G1 to S phase transition 2 | 0.00755948 |
| SORT1 | sortilin 1 | 0.00755313 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00753574 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0075347 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00750463 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00750161 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00749385 |
| RNF43 | ring finger protein 43 | 0.00742153 |
| TMEM14B | transmembrane protein 14B | 0.00736268 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | 0.00734705 |
| CFB | complement factor B | 0.00733152 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00731935 |
| LXN | latexin | 0.00731423 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.00730824 |
| URI1 | URI1, prefoldin-like chaperone | 0.00730648 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00727393 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00725873 |
| PAGE4 | P antigen family, member 4 (prostate associated) | 0.0072366 |
| GSDMB | gasdermin B | 0.00722983 |
| BCHE | butyrylcholinesterase | 0.00719896 |
| EPYC | epiphycan | 0.00712768 |
| NTS | neurotensin | 0.00707102 |
| HCRT | hypocretin (orexin) neuropeptide precursor | 0.00705615 |
| ACTN1 | actinin, alpha 1 | 0.00705092 |
| MUC16 | mucin 16, cell surface associated | 0.00703082 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00701817 |
| OAT | ornithine aminotransferase | 0.00701661 |
| YBX3 | Y box binding protein 3 | 0.00700937 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.0070035 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00699038 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00697173 |
| REG1A | regenerating islet-derived 1 alpha | 0.00689262 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00687481 |
| HIST1H2AC | histone cluster 1, H2ac | 0.0068712 |
| TASP1 | taspase, threonine aspartase, 1 | 0.00686358 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00684951 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 0.00683803 |
| ODC1 | ornithine decarboxylase 1 | 0.00683754 |
| POSTN | periostin, osteoblast specific factor | 0.00676512 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | 0.00673228 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00672275 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00671154 |
| KRT81 | keratin 81, type II | 0.00670383 |
| TRIM13 | tripartite motif containing 13 | 0.00670246 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0067011 |
| LBH | limb bud and heart development | 0.00667613 |
| CD46 | CD46 molecule, complement regulatory protein | 0.00663006 |
| ZNF395 | zinc finger protein 395 | 0.00662533 |
| RAB15 | RAB15, member RAS oncogene family | 0.00662203 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.00660012 |
| SULF1 | sulfatase 1 | 0.00659405 |
| VIL1 | villin 1 | 0.00658527 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00656819 |
| KRT14 | keratin 14, type I | 0.00656463 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00656093 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0065582 |
| MRS2 | MRS2 magnesium transporter | 0.00655308 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00654974 |
| ACP3 | acid phosphatase 3 | 0.00653912 |
| HDAC9 | histone deacetylase 9 | 0.0065384 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00652864 |
| FBXO21 | F-box protein 21 | 0.00650117 |
| ARSL | arylsulfatase L | 0.0064901 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.00648854 |
| EHF | ets homologous factor | 0.0064846 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 0.00644821 |
| SIRT5 | sirtuin 5 | 0.0064459 |
| TFEC | transcription factor EC | 0.006438 |
| GPX2 | glutathione peroxidase 2 | 0.00643004 |
| ARG2 | arginase 2 | 0.00642603 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00642005 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00641566 |
| KL | klotho | 0.00641506 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0063794 |
| GPC4 | glypican 4 | 0.00637446 |
| OLFM4 | olfactomedin 4 | 0.00636787 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.0063678 |
| FYB1 | FYN binding protein 1 | 0.0063595 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00633794 |
| HOXD3 | homeobox D3 | 0.00633135 |
| PKP2 | plakophilin 2 | 0.00632426 |
| DOK5 | docking protein 5 | 0.00632119 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00631706 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.00631129 |
| SMYD2 | SET and MYND domain containing 2 | 0.00629072 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00627538 |
| PTPRO | protein tyrosine phosphatase, receptor type, O | 0.00627167 |
| CHMP4A | charged multivesicular body protein 4A | 0.00626334 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.00625871 |
| NPC2 | Niemann-Pick disease, type C2 | 0.00625098 |
| TPM4 | tropomyosin 4 | 0.00624845 |
| CD2AP | CD2-associated protein | 0.00624518 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00621183 |
| SLC16A4 | solute carrier family 16, member 4 | 0.00621178 |
| COL10A1 | collagen, type X, alpha 1 | 0.00620477 |
| ORC4 | origin recognition complex, subunit 4 | 0.00620047 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.0061917 |
| TGIF1 | TGFB-induced factor homeobox 1 | 0.00617018 |
| NPR1 | natriuretic peptide receptor 1 | 0.00615187 |
| YME1L1 | YME1-like 1 ATPase | 0.00613725 |
| PAK1IP1 | PAK1 interacting protein 1 | 0.00612774 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00612606 |
| KLK11 | kallikrein-related peptidase 11 | 0.00609847 |
| LRRC15 | leucine rich repeat containing 15 | 0.00609589 |
| NCF2 | neutrophil cytosolic factor 2 | 0.00608135 |
| NSG1 | neuron specific gene family member 1 | 0.00607983 |
| AQP9 | aquaporin 9 | 0.0060549 |
| ZFAND1 | zinc finger, AN1-type domain 1 | 0.00605271 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00604666 |
| KIAA0226L | KIAA0226-like | 0.00603177 |
| SSPN | sarcospan | 0.00601657 |
| MISP | mitotic spindle positioning | 0.00600305 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00599763 |
| AEBP1 | AE binding protein 1 | 0.00598547 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00598433 |
| TMEM260 | transmembrane protein 260 | 0.00596403 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00593955 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 0.00593671 |
| KLK5 | kallikrein-related peptidase 5 | 0.00589484 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00584948 |
| BCL2A1 | BCL2-related protein A1 | 0.00578264 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00578064 |
| PSEN1 | presenilin 1 | 0.00576377 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.00575574 |
| MLF1 | myeloid leukemia factor 1 | 0.00574965 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0057451 |
| PRR15L | proline rich 15-like | 0.00574106 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.00573983 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00573852 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00573729 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.00573383 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | 0.00572123 |
| PINLYP | phospholipase A2 inhibitor and LY6/PLAUR domain containing | 0.0057073 |
| BANF1 | barrier to autointegration factor 1 | 0.00570645 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00570474 |
| BTG2 | BTG family, member 2 | 0.00569826 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | 0.00569195 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00568379 |
| RAG1 | recombination activating gene 1 | 0.00567752 |
| PDCD10 | programmed cell death 10 | 0.00566801 |
| ASRGL1 | asparaginase like 1 | 0.0056651 |
| CTSK | cathepsin K | 0.00565936 |
| HIST1H2BD | histone cluster 1, H2bd | 0.0056442 |
| CDC20 | cell division cycle 20 | 0.00563842 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00563805 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00562801 |
| CD1E | CD1e molecule | 0.00561114 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00560295 |
| LYPLA1 | lysophospholipase I | 0.00559642 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00559638 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0055837 |
| SMS | spermine synthase | 0.00557515 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.0055711 |
| MMP7 | matrix metallopeptidase 7 | 0.00557034 |
| LACTB2 | lactamase, beta 2 | 0.00556938 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00556164 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00555533 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog | 0.00555099 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00552638 |
| IL15 | interleukin 15 | 0.00552186 |
| ANXA1 | annexin A1 | 0.00550624 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00548869 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.00548459 |
| ITM2C | integral membrane protein 2C | 0.00547376 |
| ETNK1 | ethanolamine kinase 1 | 0.00546995 |
| EIF4E2 | eukaryotic translation initiation factor 4E family member 2 | 0.00544243 |
| SEC61G | Sec61 gamma subunit | 0.00543965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTCH1 | patched 1 | -0.0163825 |
| RTN2 | reticulon 2 | -0.0159522 |
| TNC | tenascin C | -0.0156372 |
| MGLL | monoglyceride lipase | -0.0138456 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.0131031 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0126902 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0125074 |
| TMEM45A | transmembrane protein 45A | -0.0125056 |
| MYBPC1 | myosin binding protein C, slow type | -0.0123281 |
| C1R | complement component 1, r subcomponent | -0.0122733 |
| OLFM1 | olfactomedin 1 | -0.0120068 |
| SDC2 | syndecan 2 | -0.0117195 |
| HEATR1 | HEAT repeat containing 1 | -0.0114448 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.0112482 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0111894 |
| ANXA6 | annexin A6 | -0.0111351 |
| GLTP | glycolipid transfer protein | -0.010685 |
| DIO2 | deiodinase, iodothyronine, type II | -0.0105201 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0103902 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0101867 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0101716 |
| CLU | clusterin | -0.010142 |
| HOPX | HOP homeobox | -0.010081 |
| THBS4 | thrombospondin 4 | -0.0100537 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00991047 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00988975 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00978074 |
| CDA | cytidine deaminase | -0.00968031 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00965666 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00963372 |
| GOLM1 | golgi membrane protein 1 | -0.00941214 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00939647 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00937327 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00936612 |
| COL6A1 | collagen, type VI, alpha 1 | -0.00930054 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00925136 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00922933 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00920467 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00916321 |
| LOXL2 | lysyl oxidase-like 2 | -0.00914951 |
| MEF2C | myocyte enhancer factor 2C | -0.00906369 |
| SOWAHC | sosondowah ankyrin repeat domain family member C | -0.00903826 |
| GAL | galanin/GMAP prepropeptide | -0.00896723 |
| ADCY9 | adenylate cyclase 9 | -0.00896405 |
| PRDX2 | peroxiredoxin 2 | -0.00892486 |
| STMN2 | stathmin 2 | -0.00890117 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00873308 |
| MT1E | metallothionein 1E | -0.00871087 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00859102 |
| NID1 | nidogen 1 | -0.00852188 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00851367 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00845203 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00843154 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00838052 |
| PPL | periplakin | -0.00831695 |
| NPTX2 | neuronal pentraxin II | -0.00831542 |
| CA12 | carbonic anhydrase XII | -0.0083024 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00828164 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00826725 |
| F12 | coagulation factor XII (Hageman factor) | -0.00825663 |
| GPC3 | glypican 3 | -0.00824939 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00823488 |
| PURA | purine-rich element binding protein A | -0.00821955 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00819216 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00806159 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00804526 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00798212 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00792625 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0078965 |
| AHNAK | AHNAK nucleoprotein | -0.00789132 |
| GAP43 | growth associated protein 43 | -0.00786615 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00782002 |
| NEFM | neurofilament, medium polypeptide | -0.00779432 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00778191 |
| IL6ST | interleukin 6 signal transducer | -0.00777335 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00776016 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00773288 |
| MYOT | myotilin | -0.00771734 |
| CD93 | CD93 molecule | -0.00771429 |
| MSX1 | msh homeobox 1 | -0.00769027 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00768981 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00768585 |
| DMD | dystrophin | -0.00761207 |
| SLN | sarcolipin | -0.00758541 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00755707 |
| C4BPA | complement component 4 binding protein, alpha | -0.0074771 |
| TTN | titin | -0.00745622 |
| CD14 | CD14 molecule | -0.00744485 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00742408 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.0073991 |
| PCLAF | PCNA clamp associated factor | -0.00739274 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0073416 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.00733728 |
| SORD | sorbitol dehydrogenase | -0.00733663 |
| BEX1 | brain expressed, X-linked 1 | -0.00732918 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00732271 |
| KIF20A | kinesin family member 20A | -0.00731431 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | -0.0072967 |
| TFF1 | trefoil factor 1 | -0.00725577 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.007232 |
| DST | dystonin | -0.00721494 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00721035 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00717952 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00715057 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00714584 |
| REEP1 | receptor accessory protein 1 | -0.00710026 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00709868 |
| PEG3 | paternally expressed 3 | -0.00709839 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | -0.00708889 |
| JAM3 | junctional adhesion molecule 3 | -0.00707472 |
| COMT | catechol-O-methyltransferase | -0.00704364 |
| PRDX1 | peroxiredoxin 1 | -0.00701117 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00701024 |
| PLTP | phospholipid transfer protein | -0.00700417 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00694769 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00694248 |
| CHGB | chromogranin B | -0.00692752 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.00689875 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.00684484 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00683773 |
| VWF | von Willebrand factor | -0.00682335 |
| MB | myoglobin | -0.00681509 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00680752 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00676381 |
| CHI3L2 | chitinase 3-like 2 | -0.00675116 |
| CCND1 | cyclin D1 | -0.00674169 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00671583 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00669274 |
| FSTL1 | follistatin-like 1 | -0.00668838 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00667311 |
| ABLIM1 | actin binding LIM protein 1 | -0.00664865 |
| IVD | isovaleryl-CoA dehydrogenase | -0.00664361 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00663217 |
| ARHGAP45 | Rho GTPase activating protein 45 | -0.00662846 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00662083 |
| PAX6 | paired box 6 | -0.00661694 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00661238 |
| WEE1 | WEE1 G2 checkpoint kinase | -0.0065869 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | -0.00658677 |
| TCF4 | transcription factor 4 | -0.00657236 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.0065651 |
| HHEX | hematopoietically expressed homeobox | -0.00652274 |
| EZR | ezrin | -0.00651332 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00650983 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00650181 |
| KRT17 | keratin 17, type I | -0.00649389 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00647874 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00644021 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00642947 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00642866 |
| ELOB | elongin B | -0.00640261 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00638975 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00637907 |
| TPBG | trophoblast glycoprotein | -0.00637091 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00634492 |
| RUFY3 | RUN and FYVE domain containing 3 | -0.00629645 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00628575 |
| LAMA2 | laminin, alpha 2 | -0.00626904 |
| CDCA4 | cell division cycle associated 4 | -0.00623927 |
| MGP | matrix Gla protein | -0.00623891 |
| ACTB | actin, beta | -0.00623434 |
| CENPE | centromere protein E, 312kDa | -0.00621038 |
| PRPH | peripherin | -0.00619124 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00618351 |
| METTL7A | methyltransferase like 7A | -0.00617588 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00615709 |
| EMP1 | epithelial membrane protein 1 | -0.00614052 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00613705 |
| SIRT3 | sirtuin 3 | -0.00612001 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00611937 |
| ITM2A | integral membrane protein 2A | -0.00610031 |
| S100A7 | S100 calcium binding protein A7 | -0.00609754 |
| LIMA1 | LIM domain and actin binding 1 | -0.00609537 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0060948 |
| HK2 | hexokinase 2 | -0.00609378 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | -0.00609231 |
| NELL2 | NEL-like 2 (chicken) | -0.00609164 |
| SHOX2 | short stature homeobox 2 | -0.00606747 |
| PLP1 | proteolipid protein 1 | -0.00604957 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00604637 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00603281 |
| JADE2 | jade family PHD finger 2 | -0.00602113 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00602032 |
| CADM1 | cell adhesion molecule 1 | -0.00601757 |
| GPM6A | glycoprotein M6A | -0.00599639 |
| C1S | complement component 1, s subcomponent | -0.00598655 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.00597327 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00596104 |
| INHBB | inhibin, beta B | -0.00594484 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00594132 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0059412 |
| FAM216A | family with sequence similarity 216, member A | -0.00592451 |
| TTR | transthyretin | -0.00592065 |
| SPRR2B | small proline-rich protein 2B | -0.00592044 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00591976 |
| CNR1 | cannabinoid receptor 1 (brain) | -0.00590828 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.00590648 |
| MAEA | macrophage erythroblast attacher | -0.00587901 |
| FAM102A | family with sequence similarity 102, member A | -0.0058782 |
| RASIP1 | Ras interacting protein 1 | -0.00585396 |
| CBX6 | chromobox homolog 6 | -0.00584112 |
| DLX2 | distal-less homeobox 2 | -0.00580725 |
| NSF | N-ethylmaleimide-sensitive factor | -0.0058064 |
| APLNR | apelin receptor | -0.00578833 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00577973 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.00577753 |
| RGS5 | regulator of G-protein signaling 5 | -0.00577234 |
| CD302 | CD302 molecule | -0.00577137 |
| RTL8C | retrotransposon Gag like 8C | -0.00577023 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00576124 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | -0.00575106 |
| TSPAN5 | tetraspanin 5 | -0.00574847 |
| NLGN4X | neuroligin 4, X-linked | -0.00574648 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.00574125 |
| STC1 | stanniocalcin 1 | -0.00574039 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00570468 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00569094 |
| OSMR | oncostatin M receptor | -0.00568106 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00567817 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0056677 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00564525 |
| EVA1B | eva-1 homolog B (C. elegans) | -0.00564518 |
| DSG3 | desmoglein 3 | -0.00564037 |
| CLCA4 | chloride channel accessory 4 | -0.00563583 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00562847 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00561474 |
| ANGPTL2 | angiopoietin-like 2 | -0.00561104 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00560821 |
| CLEC3B | C-type lectin domain family 3, member B | -0.00559829 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00559648 |
| BAG1 | BCL2-associated athanogene | -0.00559467 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00559259 |
| TUBA4A | tubulin, alpha 4a | -0.00557844 |
| MRC2 | mannose receptor, C type 2 | -0.0055779 |
| ADCY3 | adenylate cyclase 3 | -0.00555891 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00555841 |
| ARHGAP19 | Rho GTPase activating protein 19 | -0.00555382 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00554799 |
| SECISBP2L | SECIS binding protein 2-like | -0.00554722 |
| QKI | QKI, KH domain containing, RNA binding | -0.00552521 |
| PLK1 | polo-like kinase 1 | -0.00551687 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00550437 |
| L1CAM | L1 cell adhesion molecule | -0.00548616 |
| RXRA | retinoid X receptor, alpha | -0.00548542 |
| TYMP | thymidine phosphorylase | -0.00547966 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00546894 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.00546882 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00544872 |
| RHOB | ras homolog family member B | -0.0054474 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00543664 |
