PASK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PAS domain containing serine/threonine kinase|This gene encodes a member of the serine/threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 23178)
External Link http://www.ncbi.nlm.nih.gov/gene/23178
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Genes

113 interacting proteins for PASK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAG6 BCL2-associated athanogene 6
BECN1 beclin 1, autophagy related
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
C2ORF44 chromosome 2 open reading frame 44
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCP110 centriolar coiled coil protein 110kDa
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEP78 centrosomal protein 78kDa
CEP97 centrosomal protein 97kDa
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNOT11 CCR4-NOT transcription complex, subunit 11
CNOT12 CCR4-NOT transcription complex subunit 12
CNOT2 CCR4-NOT transcription complex, subunit 2
CNOT3 CCR4-NOT transcription complex, subunit 3
CREB1 cAMP responsive element binding protein 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
EDARADD EDAR-associated death domain
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EIF3G eukaryotic translation initiation factor 3, subunit G
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EMILIN3 elastin microfibril interfacer 3
FAM120A family with sequence similarity 120A
FAM222A family with sequence similarity 222, member A
FAM222B family with sequence similarity 222, member B
FBL fibrillarin
FGA fibrinogen alpha chain
FXN frataxin
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GYG1 glycogenin 1
GYS1 glycogen synthase 1 (muscle)
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HJURP Holliday junction recognition protein
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB1 heat shock 27kDa protein 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL2RA interleukin 2 receptor, alpha
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIAA0226 KIAA0226
KIAA0226L KIAA0226-like
KIF5B kinesin family member 5B
KPNB1 karyopherin (importin) beta 1
KRT8 keratin 8, type II
LAS1L LAS1-like (S. cerevisiae)
LMNA lamin A/C
LMNB1 lamin B1
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
MET MET proto-oncogene, receptor tyrosine kinase
MKI67 marker of proliferation Ki-67
NCF1 neutrophil cytosolic factor 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NLK nemo-like kinase
NOL9 nucleolar protein 9
NOM1 nucleolar protein with MIF4G domain 1
NUP160 nucleoporin 160kDa
OBSL1 obscurin-like 1
PDX1 pancreatic and duodenal homeobox 1
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PHKB phosphorylase kinase, beta
PIAS1 protein inhibitor of activated STAT, 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKM pyruvate kinase, muscle
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRPF6 pre-mRNA processing factor 6
PRR14L proline rich 14-like
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTPRA protein tyrosine phosphatase, receptor type, A
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB4A RAB4A, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RECQL4 RecQ protein-like 4
RGPD4 RANBP2-like and GRIP domain containing 4
RNF219 ring finger protein 219
RPS6 ribosomal protein S6
SENP5 SUMO1/sentrin specific peptidase 5
SHANK2 SH3 and multiple ankyrin repeat domains 2
SKI SKI proto-oncogene
SMAD4 SMAD family member 4
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
STK16 serine/threonine kinase 16
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TLE3 transducin-like enhancer of split 3
TOP2B topoisomerase (DNA) II beta 180kDa
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
UBAP2L ubiquitin associated protein 2-like
UBC ubiquitin C
UVRAG UV radiation resistance associated
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VTN vitronectin
WDR5 WD repeat domain 5
WDR6 WD repeat domain 6
ZBTB21 zinc finger and BTB domain containing 21
ZBTB24 zinc finger and BTB domain containing 24
ZNF574 zinc finger protein 574
ZNF628 zinc finger protein 628
ZNF638 zinc finger protein 638
ZNF768 zinc finger protein 768