PAWR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description PRKC, apoptosis, WT1, regulator|The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5074)
External Link https://ncbi.nlm.nih.gov/gene/5074
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Genes

498 genes differentially expressed following the PAWR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0211107
RTN2 reticulon 2 0.0153874
MYBPC1 myosin binding protein C, slow type 0.0137771
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.012825
FABP4 fatty acid binding protein 4, adipocyte 0.0127923
MEF2C myocyte enhancer factor 2C 0.01267
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.0124951
GSTM3 glutathione S-transferase mu 3 (brain) 0.0123767
SCGB2A2 secretoglobin, family 2A, member 2 0.0122774
SGCE sarcoglycan, epsilon 0.0111634
GBP2 guanylate binding protein 2, interferon-inducible 0.0109129
ZFPM2 zinc finger protein, FOG family member 2 0.0106818
EGR3 early growth response 3 0.010577
FBN1 fibrillin 1 0.0104332
TFF3 trefoil factor 3 (intestinal) 0.010217
SCGB2A1 secretoglobin, family 2A, member 1 0.0101599
TFF1 trefoil factor 1 0.0101297
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00996909
CD200 CD200 molecule 0.00996774
RCAN1 regulator of calcineurin 1 0.00996631
DMD dystrophin 0.00990083
ACKR3 atypical chemokine receptor 3 0.00976876
BST2 bone marrow stromal cell antigen 2 0.00967141
GOLGA8A golgin A8 family, member A 0.00966034
GJA1 gap junction protein, alpha 1, 43kDa 0.00961044
IFI44L interferon-induced protein 44-like 0.00952934
MX1 MX dynamin-like GTPase 1 0.00946975
TNNT1 troponin T type 1 (skeletal, slow) 0.00944673
S100P S100 calcium binding protein P 0.0094382
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0094244
EGR1 early growth response 1 0.00928373
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00924271
NAV3 neuron navigator 3 0.00911705
SCGB1D2 secretoglobin, family 1D, member 2 0.00901734
KIAA0100 KIAA0100 0.00895866
SYT1 synaptotagmin I 0.00894239
PUDP pseudouridine 5'-phosphatase 0.00875679
ANK2 ankyrin 2, neuronal 0.00875373
DCN decorin 0.00872691
LRRN3 leucine rich repeat neuronal 3 0.00871142
NRCAM neuronal cell adhesion molecule 0.00862689
SELE selectin E 0.00859473
ELANE elastase, neutrophil expressed 0.00858866
STC2 stanniocalcin 2 0.00847685
MAGEA3 melanoma antigen family A3 0.00843236
KRT7 keratin 7, type II 0.00841668
PDE4B phosphodiesterase 4B, cAMP-specific 0.00837005
VWF von Willebrand factor 0.00825612
AGR2 anterior gradient 2 0.00824695
SOBP sine oculis binding protein homolog (Drosophila) 0.00821369
SRPX sushi-repeat containing protein, X-linked 0.00820718
KLF4 Kruppel-like factor 4 (gut) 0.00815844
SRGN serglycin 0.00811647
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00810724
EIF5 eukaryotic translation initiation factor 5 0.00808807
APOD apolipoprotein D 0.00806437
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00805459
ADGRL4 adhesion G protein-coupled receptor L4 0.00797851
EGR2 early growth response 2 0.00793497
CFD complement factor D (adipsin) 0.00792313
OXA1L oxidase (cytochrome c) assembly 1-like 0.00789074
CRYAB crystallin, alpha B 0.00788523
JAM2 junctional adhesion molecule 2 0.00786662
RGCC regulator of cell cycle 0.00784199
MECOM MDS1 and EVI1 complex locus 0.00783238
OGN osteoglycin 0.00781739
ATXN1 ataxin 1 0.00777406
AKAP12 A kinase (PRKA) anchor protein 12 0.00772753
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00771851
CDH5 cadherin 5, type 2 (vascular endothelium) 0.007709
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00770624
TFRC transferrin receptor 0.00765426
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00764635
EMCN endomucin 0.00755776
LRRC17 leucine rich repeat containing 17 0.00753226
STMN2 stathmin 2 0.00751031
NID1 nidogen 1 0.00750904
DMTF1 cyclin D binding myb-like transcription factor 1 0.00746088
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00741777
MAGEA1 melanoma antigen family A1 0.00735776
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00733725
ZNF83 zinc finger protein 83 0.00732844
CCN2 cellular communication network factor 2 0.0073138
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00730611
FAR2 fatty acyl CoA reductase 2 0.00729809
PEG10 paternally expressed 10 0.0072965
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.0072631
TTN titin 0.00724098
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00721603
LAMP5 lysosomal-associated membrane protein family, member 5 0.00719529
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.00717181
LHFP lipoma HMGIC fusion partner 0.00713514
ADGRL2 adhesion G protein-coupled receptor L2 0.00713452
TCF4 transcription factor 4 0.0071163
VEGFC vascular endothelial growth factor C 0.00709687
HBEGF heparin-binding EGF-like growth factor 0.00708515
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00703441
HILPDA hypoxia inducible lipid droplet-associated 0.00701645
GLT8D2 glycosyltransferase 8 domain containing 2 0.00698697
IFI27 interferon, alpha-inducible protein 27 0.00698366
PFKP phosphofructokinase, platelet 0.00697507
FMO1 flavin containing monooxygenase 1 0.00695946
MAGEA12 melanoma antigen family A12 0.00695547
CDC42 cell division cycle 42 0.0069541
MEG3 maternally expressed 3 (non-protein coding) 0.00694417
EFHD1 EF-hand domain family, member D1 0.00692288
ANO1 anoctamin 1, calcium activated chloride channel 0.00690496
MYOT myotilin 0.00689591
TNNC1 troponin C type 1 (slow) 0.00686595
CA2 carbonic anhydrase II 0.00686408
GUSBP3 glucuronidase, beta pseudogene 3 0.00685472
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00685326
NREP neuronal regeneration related protein 0.00684392
ANXA3 annexin A3 0.00683088
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00682815
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00678876
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00678072
CAV2 caveolin 2 0.0067483
LAMA2 laminin, alpha 2 0.00674133
WSB1 WD repeat and SOCS box containing 1 0.00672582
HOXC6 homeobox C6 0.00671249
NCALD neurocalcin delta 0.00666291
SMC1A structural maintenance of chromosomes 1A 0.00664592
RIOX2 ribosomal oxygenase 2 0.00663264
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.00662076
PEG3 paternally expressed 3 0.00660921
GPM6A glycoprotein M6A 0.00660514
COL14A1 collagen, type XIV, alpha 1 0.00659272
CANX calnexin 0.00655998
CTSG cathepsin G 0.00653709
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.00653571
SMAD3 SMAD family member 3 0.00652967
FLNB filamin B, beta 0.0065276
TNNI1 troponin I type 1 (skeletal, slow) 0.00652489
NBEA neurobeachin 0.00650927
NBPF10 neuroblastoma breakpoint family, member 10 0.00650854
JAM3 junctional adhesion molecule 3 0.00650511
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00646824
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00646261
GAP43 growth associated protein 43 0.00645445
ARMCX1 armadillo repeat containing, X-linked 1 0.00641992
RHOBTB3 Rho-related BTB domain containing 3 0.00641834
FHL1 four and a half LIM domains 1 0.00641033
ZEB1 zinc finger E-box binding homeobox 1 0.00637204
COL15A1 collagen, type XV, alpha 1 0.00633461
PBX3 pre-B-cell leukemia homeobox 3 0.00631653
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00631274
MAB21L1 mab-21-like 1 (C. elegans) 0.00630675
FLT1 fms-related tyrosine kinase 1 0.0062997
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00624612
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00622387
IFI44 interferon-induced protein 44 0.00622375
SNAP25 synaptosomal-associated protein, 25kDa 0.00621345
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00620563
AZU1 azurocidin 1 0.00619554
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00619246
CHGB chromogranin B 0.0061866
CPE carboxypeptidase E 0.00615784
ANGPT2 angiopoietin 2 0.00615732
MAB21L2 mab-21-like 2 (C. elegans) 0.00615348
WWTR1 WW domain containing transcription regulator 1 0.00615133
PALMD palmdelphin 0.00614851
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00613398
AMOTL2 angiomotin like 2 0.00613119
LAMA4 laminin, alpha 4 0.0060979
GPM6B glycoprotein M6B 0.00609628
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00608866
TYMS thymidylate synthetase 0.0060851
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00608238
CXCL12 chemokine (C-X-C motif) ligand 12 0.00607741
MCL1 myeloid cell leukemia 1 0.00605499
MYOF myoferlin 0.00603809
ZNF185 zinc finger protein 185 (LIM domain) 0.00603401
MSL1 male-specific lethal 1 homolog (Drosophila) 0.00600278
TRAK1 trafficking protein, kinesin binding 1 0.00598606
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00597895
PLP1 proteolipid protein 1 0.00595141
KLHL41 kelch-like family member 41 0.00594529
TPM3 tropomyosin 3 0.00591899
KDM6A lysine (K)-specific demethylase 6A 0.00591099
FRY furry homolog (Drosophila) 0.00590566
COLEC12 collectin sub-family member 12 0.00587818
TENT5A terminal nucleotidyltransferase 5A 0.00584099
PDLIM5 PDZ and LIM domain 5 0.00583452
MYOZ2 myozenin 2 0.00583421
RANBP9 RAN binding protein 9 0.00583386
MMP2 matrix metallopeptidase 2 0.0058279
ITM2A integral membrane protein 2A 0.00580882
STARD13 StAR-related lipid transfer (START) domain containing 13 0.00580777
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00579548
TPBG trophoblast glycoprotein 0.00578575
CRYBG3 beta-gamma crystallin domain containing 3 0.00578349
MGP matrix Gla protein 0.00578084
DST dystonin 0.00577826
RBM5 RNA binding motif protein 5 0.00577635
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.00577189
BCAR3 breast cancer anti-estrogen resistance 3 0.00575781
CSRP2 cysteine and glycine-rich protein 2 0.00574917
IGFBP5 insulin-like growth factor binding protein 5 0.00572767
MEOX2 mesenchyme homeobox 2 0.00572674
ARMCX2 armadillo repeat containing, X-linked 2 0.00571705
STX12 syntaxin 12 0.00571567
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00571509
JCAD junctional cadherin 5 associated 0.00570792
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.00570193
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.00569722
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00568898
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00568459
SPARCL1 SPARC-like 1 (hevin) 0.0056738
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00566106
CCNG2 cyclin G2 0.00565516
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.0056509
POSTN periostin, osteoblast specific factor 0.00564828
C14ORF132 chromosome 14 open reading frame 132 0.00564719
QKI QKI, KH domain containing, RNA binding 0.00563482
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00560913
GAB2 GRB2-associated binding protein 2 0.00559505
ZC2HC1A zinc finger, C2HC-type containing 1A 0.00558843
CD34 CD34 molecule 0.00555574
FYCO1 FYVE and coiled-coil domain containing 1 0.00554667
AK5 adenylate kinase 5 0.00551771
MID1IP1 MID1 interacting protein 1 0.00549004
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.00546111
AREG amphiregulin 0.00546083
ATF3 activating transcription factor 3 0.00544736
THSD7A thrombospondin, type I, domain containing 7A 0.00543997
RELN reelin 0.00542617
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.00541775
PRMT5 protein arginine methyltransferase 5 0.00541035
CD93 CD93 molecule 0.00539534
G0S2 G0/G1 switch 2 0.00538593
HOXB6 homeobox B6 0.005379
CKM creatine kinase, muscle 0.00536157
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00535631
CDR2L cerebellar degeneration-related protein 2-like 0.00535435
PRSS3 protease, serine, 3 0.00534706
DAXX death-domain associated protein 0.00534482
LOXL2 lysyl oxidase-like 2 0.00531819
HHEX hematopoietically expressed homeobox 0.00529717
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00529672
HOMER1 homer scaffolding protein 1 0.00529652
MX2 MX dynamin-like GTPase 2 0.00529106
PNN pinin, desmosome associated protein 0.00528601
GRAMD2B GRAM domain containing 2B 0.00528405
DLK1 delta-like 1 homolog (Drosophila) 0.00528103
AKAP17A A kinase (PRKA) anchor protein 17A 0.00527686
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.00527652
HSPA8 heat shock 70kDa protein 8 0.00527347
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00527138

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0258184
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0165473
MMP7 matrix metallopeptidase 7 -0.0149754
CHP1 calcineurin-like EF-hand protein 1 -0.0147923
KDM5D lysine (K)-specific demethylase 5D -0.0144672
AQP3 aquaporin 3 (Gill blood group) -0.0135227
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0127939
IL7R interleukin 7 receptor -0.0127722
TXNDC9 thioredoxin domain containing 9 -0.0122513
CFB complement factor B -0.0110991
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0109908
TGFBI transforming growth factor, beta-induced, 68kDa -0.0107934
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.010608
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0105801
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00992017
CD8A CD8a molecule -0.0098573
DIPK1A divergent protein kinase domain 1A -0.00976978
GZMK granzyme K (granzyme 3; tryptase II) -0.00969301
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00965119
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00960562
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00938172
CD2 CD2 molecule -0.0090523
GAL galanin/GMAP prepropeptide -0.00899767
LBH limb bud and heart development -0.00885361
NELL2 NEL-like 2 (chicken) -0.00880328
PDZK1IP1 PDZK1 interacting protein 1 -0.00875064
AMACR alpha-methylacyl-CoA racemase -0.00862656
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00860089
CCL5 chemokine (C-C motif) ligand 5 -0.00856887
PRR7 proline rich 7 (synaptic) -0.00852746
SORD sorbitol dehydrogenase -0.00844119
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00832713
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0082984
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -0.00827105
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00825241
FGG fibrinogen gamma chain -0.00818267
SLCO1B3 solute carrier organic anion transporter family, member 1B3 -0.00810927
SIRT3 sirtuin 3 -0.00793141
NRIP3 nuclear receptor interacting protein 3 -0.00792417
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00789278
IGFBP1 insulin-like growth factor binding protein 1 -0.00786193
NVL nuclear VCP-like -0.00784872
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00781872
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00777228
PRF1 perforin 1 (pore forming protein) -0.00775483
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00772408
GCLC glutamate-cysteine ligase, catalytic subunit -0.00771182
AQP9 aquaporin 9 -0.00770511
TRIB2 tribbles pseudokinase 2 -0.00758207
TPSAB1 tryptase alpha/beta 1 -0.00754472
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00749478
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00747928
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.00747612
EIF5A eukaryotic translation initiation factor 5A -0.00747469
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.00747096
DHCR24 24-dehydrocholesterol reductase -0.00743554
RBPMS RNA binding protein with multiple splicing -0.00742898
WT1 Wilms tumor 1 -0.00738699
TGFA transforming growth factor, alpha -0.00737863
NFE2L2 nuclear factor, erythroid 2-like 2 -0.00730776
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00725384
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00721813
HP haptoglobin -0.00716094
SQLE squalene epoxidase -0.00715688
NTS neurotensin -0.007123
PON3 paraoxonase 3 -0.0071204
STK26 serine/threonine protein kinase 26 -0.00697933
A2M alpha-2-macroglobulin -0.00696196
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00694776
IFITM1 interferon induced transmembrane protein 1 -0.00694619
ACP5 acid phosphatase 5, tartrate resistant -0.00685838
GNLY granulysin -0.00681178
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00679419
RAPSN receptor-associated protein of the synapse -0.00676639
JCHAIN joining chain of multimeric IgA and IgM -0.00675547
C4BPA complement component 4 binding protein, alpha -0.006691
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0066823
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00668014
CTSH cathepsin H -0.00664079
S100A2 S100 calcium binding protein A2 -0.00659827
PRKCQ protein kinase C, theta -0.00659217
C3 complement component 3 -0.00658591
CD52 CD52 molecule -0.00656924
RNF43 ring finger protein 43 -0.00654045
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00653233
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -0.00652022
RUNX3 runt-related transcription factor 3 -0.00649981
HPD 4-hydroxyphenylpyruvate dioxygenase -0.00649047
PON2 paraoxonase 2 -0.00648851
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00645809
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -0.00645108
TCF7 transcription factor 7 (T-cell specific, HMG-box) -0.00643303
GLYAT glycine-N-acyltransferase -0.00642025
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -0.00636744
CD81 CD81 molecule -0.00635796
RETREG1 reticulophagy regulator 1 -0.00635747
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -0.00633279
IDO1 indoleamine 2,3-dioxygenase 1 -0.00629872
SUB1 SUB1 homolog (S. cerevisiae) -0.0062906
DPEP1 dipeptidase 1 (renal) -0.00627354
TFPI2 tissue factor pathway inhibitor 2 -0.00627122
XCL1 chemokine (C motif) ligand 1 -0.00625507
APOC1 apolipoprotein C-I -0.00624169
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0062187
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00621559
MOCOS molybdenum cofactor sulfurase -0.00620357
SALL1 spalt-like transcription factor 1 -0.00615877
NPM3 nucleophosmin/nucleoplasmin 3 -0.00615282
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00612701
GPX2 glutathione peroxidase 2 -0.00610849
CD84 CD84 molecule -0.00607624
CD6 CD6 molecule -0.0060596
CCL19 chemokine (C-C motif) ligand 19 -0.00603579
PRKCI protein kinase C, iota -0.00601883
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00601058
LEF1 lymphoid enhancer-binding factor 1 -0.00596896
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00595948
EXPH5 exophilin 5 -0.00591682
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -0.00591162
PFN1 profilin 1 -0.00590313
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00586167
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00585275
CHKB choline kinase beta -0.00585148
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00580456
CTH cystathionine gamma-lyase -0.005797
AMBP alpha-1-microglobulin/bikunin precursor -0.00576334
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00576283
CD27 CD27 molecule -0.0057606
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.00576008
NPC2 Niemann-Pick disease, type C2 -0.00575473
CAPG capping protein (actin filament), gelsolin-like -0.00573026
ELOVL6 ELOVL fatty acid elongase 6 -0.00572604
EPCAM epithelial cell adhesion molecule -0.00571164
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00570053
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00569866
FKBP11 FK506 binding protein 11, 19 kDa -0.00568829
APOA2 apolipoprotein A-II -0.00568054
RAB20 RAB20, member RAS oncogene family -0.00567803
KLRD1 killer cell lectin-like receptor subfamily D, member 1 -0.00565536
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -0.00564712
AZF1 azoospermia factor 1 -0.00563379
CD9 CD9 molecule -0.0056296
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00562106
NKX3-1 NK3 homeobox 1 -0.00560279
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.00558906
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00556845
CPB1 carboxypeptidase B1 (tissue) -0.0055475
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00554164
HOMER2 homer scaffolding protein 2 -0.00554088
FPR3 formyl peptide receptor 3 -0.00553936
PSPH phosphoserine phosphatase -0.005533
DENND2D DENN/MADD domain containing 2D -0.00552634
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00552155
LTB lymphotoxin beta (TNF superfamily, member 3) -0.00551409
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00549734
TTC38 tetratricopeptide repeat domain 38 -0.00547994
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -0.0054638
GSAP gamma-secretase activating protein -0.00545193
CNTN1 contactin 1 -0.00545085
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -0.00544935
HPN hepsin -0.00544772
CST3 cystatin C -0.00544633
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00542654
KRAS Kirsten rat sarcoma viral oncogene homolog -0.00541139
TWF1 twinfilin actin binding protein 1 -0.00539675
OSBPL10 oxysterol binding protein-like 10 -0.00539268
MSMO1 methylsterol monooxygenase 1 -0.00539151
GTPBP8 GTP-binding protein 8 (putative) -0.00538697
CPM carboxypeptidase M -0.0053812
C1S complement component 1, s subcomponent -0.00537526
PRKCB protein kinase C, beta -0.00537328
LAPTM4B lysosomal protein transmembrane 4 beta -0.0053702
AHSG alpha-2-HS-glycoprotein -0.00536455
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -0.00535683
PTK7 protein tyrosine kinase 7 (inactive) -0.00534803
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00533682
SPON2 spondin 2, extracellular matrix protein -0.00533093
FYB1 FYN binding protein 1 -0.00531942
PRR5 proline rich 5 (renal) -0.00531866
TRAF5 TNF receptor-associated factor 5 -0.00531252
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha -0.00530345
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00529768
AEBP1 AE binding protein 1 -0.00529382
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00528782
FABP1 fatty acid binding protein 1, liver -0.00527986
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00527712
CPB2 carboxypeptidase B2 (plasma) -0.00527405
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00526062
HPR haptoglobin-related protein -0.0052606
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa -0.00524566
TUBB2A tubulin, beta 2A class IIa -0.00523586
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) -0.00522846
PIPOX pipecolic acid oxidase -0.00522796
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00521157
CRYM crystallin, mu -0.00520727
PLA1A phospholipase A1 member A -0.00520394
LYZ lysozyme -0.00517646
NANS N-acetylneuraminic acid synthase -0.00517137
CPA3 carboxypeptidase A3 (mast cell) -0.00517023
TSC22D1 TSC22 domain family, member 1 -0.00516872
IL32 interleukin 32 -0.00516702
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00515616
ADH6 alcohol dehydrogenase 6 (class V) -0.00514854
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00514144
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00514135
RPA3 replication protein A3, 14kDa -0.00512686
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00511044
HSPA2 heat shock 70kDa protein 2 -0.00510882
ABHD6 abhydrolase domain containing 6 -0.00510385
TGM2 transglutaminase 2 -0.0050926
KHSRP KH-type splicing regulatory protein -0.00509002
PDZD8 PDZ domain containing 8 -0.00508794
SEPTIN10 septin 10 -0.00508369
IL2RB interleukin 2 receptor, beta -0.00507216
SFTPD surfactant protein D -0.00506574
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00506457
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00506248
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.005048
WFDC2 WAP four-disulfide core domain 2 -0.00503585
GRAMD4 GRAM domain containing 4 -0.0050327
MAOA monoamine oxidase A -0.00502779
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00502494
PKP3 plakophilin 3 -0.00502469
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0050153
APOM apolipoprotein M -0.00501035
GMPR guanosine monophosphate reductase -0.0050059
SLC22A18 solute carrier family 22, member 18 -0.00500562
VEGFA vascular endothelial growth factor A -0.00499977
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00499912
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.00499464
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.00498203
MAP7 microtubule-associated protein 7 -0.00497494
F12 coagulation factor XII (Hageman factor) -0.00497161
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00497108
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -0.00495945
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00494912
HMGN4 high mobility group nucleosomal binding domain 4 -0.00494612
ABHD4 abhydrolase domain containing 4 -0.00493524
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00493461
SDS serine dehydratase -0.00493077
PAEP progestagen-associated endometrial protein -0.00492567
TMEM255A transmembrane protein 255A -0.00492563
ASS1 argininosuccinate synthase 1 -0.00492343
NPY1R neuropeptide Y receptor Y1 -0.00491517
POU2AF1 POU class 2 associating factor 1 -0.00491455
DMBT1 deleted in malignant brain tumors 1 -0.00491393
GOLIM4 golgi integral membrane protein 4 -0.00491193
YBX3 Y box binding protein 3 -0.00491043
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.00490071