PAWR Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PRKC, apoptosis, WT1, regulator|The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5074)
External Link http://www.ncbi.nlm.nih.gov/gene/5074
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272 interacting proteins for PAWR from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
ABLIM1 actin binding LIM protein 1
ABLIM3 actin binding LIM protein family, member 3
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ANXA2 annexin A2
ANXA6 annexin A6
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APEH acylaminoacyl-peptide hydrolase
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATAD3A ATPase family, AAA domain containing 3A
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BCLAF1 BCL2-associated transcription factor 1
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAND1 cullin-associated and neddylation-dissociated 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CARS cysteinyl-tRNA synthetase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBR1 carbonyl reductase 1
CCAR1 cell division cycle and apoptosis regulator 1
CCDC85C coiled-coil domain containing 85C
CCM2L cerebral cavernous malformation 2-like
CD2AP CD2-associated protein
CD59 CD59 molecule, complement regulatory protein
CENPT centromere protein T
CFL1 cofilin 1 (non-muscle)
CFL2 cofilin 2 (muscle)
CORO1B coronin, actin binding protein, 1B
CORO1C coronin, actin binding protein, 1C
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTTN cortactin
DAPK3 death-associated protein kinase 3
DBN1 drebrin 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLD dihydrolipoamide dehydrogenase
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DRD2 dopamine receptor D2
DST dystonin
DUT deoxyuridine triphosphatase
DYNLL1 dynein, light chain, LC8-type 1
EED embryonic ectoderm development
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1G eukaryotic translation elongation factor 1 gamma
EEF2 eukaryotic translation elongation factor 2
EGFR epidermal growth factor receptor
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4A3 eukaryotic translation initiation factor 4A3
EPPK1 epiplakin 1
FAM129B family with sequence similarity 129, member B
FBXO25 F-box protein 25
FBXO45 F-box protein 45
FGFR1OP FGFR1 oncogene partner
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLNB filamin B, beta
FSCN1 fascin actin-bundling protein 1
GMFB glia maturation factor, beta
GRB2 growth factor receptor-bound protein 2
GRWD1 glutamate-rich WD repeat containing 1
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
H3F3A H3 histone, family 3A
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HIST1H2BH histone cluster 1, H2bh
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTRA1 HtrA serine peptidase 1
IDE insulin-degrading enzyme
IFT20 intraflagellar transport 20
IFT54 intraflagellar transport 54
ILF3 interleukin enhancer binding factor 3, 90kDa
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
IPO7 importin 7
IQGAP1 IQ motif containing GTPase activating protein 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JMJD6 jumonji domain containing 6
KIF23 kinesin family member 23
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
LIMA1 LIM domain and actin binding 1
LMNA lamin A/C
LMO7 LIM domain 7
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
LUC7L2 LUC7-like 2 (S. cerevisiae)
LUZP1 leucine zipper protein 1
MATR3 matrin 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPRIP myosin phosphatase Rho interacting protein
MYH10 myosin, heavy chain 10, non-muscle
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO1A myosin IA
MYO1B myosin IB
MYO1C myosin IC
MYO3B myosin IIIB
MYO6 myosin VI
NEXN nexilin (F actin binding protein)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NONO non-POU domain containing, octamer-binding
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCLEOLIN nucleolin multifunctional protein
PABPC1 poly(A) binding protein, cytoplasmic 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PDCD6 programmed cell death 6
PDLIM7 PDZ and LIM domain 7 (enigma)
PHGDH phosphoglycerate dehydrogenase
PKM pyruvate kinase, muscle
PLEC plectin
PLS3 plastin 3
PML promyelocytic leukemia
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRDX1 peroxiredoxin 1
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT5 protein arginine methyltransferase 5
PTBP1 polypyrimidine tract binding protein 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RACGAP1 Rac GTPase activating protein 1
RAI14 retinoic acid induced 14
RBBP7 retinoblastoma binding protein 7
RCC2 regulator of chromosome condensation 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPL10 ribosomal protein L10
RPL12 ribosomal protein L12
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL21 ribosomal protein L21
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL7 ribosomal protein L7
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS18 ribosomal protein S18
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS28 ribosomal protein S28
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS5 ribosomal protein S5
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
S100A6 S100 calcium binding protein A6
SAFB2 scaffold attachment factor B2
SAPCD2 suppressor APC domain containing 2
SCIN scinderin
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHCBP1 SHC SH2-domain binding protein 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SNX2 sorting nexin 2
SNX6 sorting nexin 6
SOS1 son of sevenless homolog 1 (Drosophila)
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRP9 signal recognition particle 9kDa
SRSF10 serine/arginine-rich splicing factor 10
SSBP1 single-stranded DNA binding protein 1, mitochondrial
STAT1 signal transducer and activator of transcription 1, 91kDa
SVIL supervillin
SYNPO synaptopodin
TAOK2 TAO kinase 2
TES testin LIM domain protein
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
THAP1 THAP domain containing, apoptosis associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TIAF1 TGFB1-induced anti-apoptotic factor 1
TLN2 talin 2
TMOD3 tropomodulin 3 (ubiquitous)
TOP1 topoisomerase (DNA) I
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TUBA1B tubulin, alpha 1b
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB3 tubulin, beta 3 class III
TUBB4B tubulin, beta 4B class IVb
TUFM Tu translation elongation factor, mitochondrial
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBB ubiquitin B
UBC ubiquitin C
UGDH UDP-glucose 6-dehydrogenase
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCL vinculin
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
WDR1 WD repeat domain 1
WT1 Wilms tumor 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6