PAX1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description paired box 1|This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 5075)
External Link http://www.ncbi.nlm.nih.gov/gene/5075
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Genes

3 interacting proteins for PAX1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
HNF4A hepatocyte nuclear factor 4, alpha
MEOX1 mesenchyme homeobox 1
MEOX2 mesenchyme homeobox 2