| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | PDZ binding kinase|This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 55872) |
| External Link | https://ncbi.nlm.nih.gov/gene/55872 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the PBK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | 0.0208741 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.015469 |
| ZNF589 | zinc finger protein 589 | 0.0150143 |
| TMSB15A | thymosin beta 15a | 0.0131796 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.0128309 |
| KIAA0100 | KIAA0100 | 0.0126026 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.011391 |
| LOXL1 | lysyl oxidase-like 1 | 0.0111045 |
| TLCD3A | TLC domain containing 3A | 0.0110164 |
| HOPX | HOP homeobox | 0.0107578 |
| NPTX2 | neuronal pentraxin II | 0.0103658 |
| ESR1 | estrogen receptor 1 | 0.0102894 |
| FZD5 | frizzled class receptor 5 | 0.00989777 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00980816 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00944428 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00941816 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00917957 |
| SFTPC | surfactant protein C | 0.00907793 |
| CORO1C | coronin, actin binding protein, 1C | 0.00895889 |
| HOXB7 | homeobox B7 | 0.00895726 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.00893298 |
| EMP2 | epithelial membrane protein 2 | 0.00855177 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00845412 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00842524 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00840298 |
| GPC4 | glypican 4 | 0.00840078 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00834656 |
| HOXB6 | homeobox B6 | 0.00832966 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.0082686 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00825079 |
| FASN | fatty acid synthase | 0.00813093 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | 0.00799467 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00786206 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00783592 |
| CRIP2 | cysteine-rich protein 2 | 0.00776731 |
| GCHFR | GTP cyclohydrolase I feedback regulator | 0.00765962 |
| SFTPA2 | surfactant protein A2 | 0.00752878 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00745773 |
| CD99 | CD99 molecule | 0.00742108 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00741823 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00741801 |
| ARG2 | arginase 2 | 0.00727811 |
| SHROOM2 | shroom family member 2 | 0.00724508 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00722654 |
| CDC42 | cell division cycle 42 | 0.00716441 |
| NVL | nuclear VCP-like | 0.00715685 |
| CRYM | crystallin, mu | 0.00715565 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00714177 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | 0.0071094 |
| FLNA | filamin A, alpha | 0.00704584 |
| TSPAN13 | tetraspanin 13 | 0.00704393 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.00702866 |
| IL17RB | interleukin 17 receptor B | 0.0070178 |
| CD52 | CD52 molecule | 0.00699446 |
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.00698082 |
| ACP3 | acid phosphatase 3 | 0.00697374 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00695156 |
| PRKCB | protein kinase C, beta | 0.00692212 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00690946 |
| GRHL2 | grainyhead-like 2 (Drosophila) | 0.00689043 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00688037 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00686958 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00686098 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00685869 |
| EMX2 | empty spiracles homeobox 2 | 0.00685806 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00683558 |
| IFT57 | intraflagellar transport 57 | 0.00680072 |
| ODC1 | ornithine decarboxylase 1 | 0.00677576 |
| SFTPB | surfactant protein B | 0.00673302 |
| MRS2 | MRS2 magnesium transporter | 0.00670533 |
| COQ8A | coenzyme Q8A | 0.00667468 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00664529 |
| IFT52 | intraflagellar transport 52 | 0.00663982 |
| APOA1 | apolipoprotein A-I | 0.0066361 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00663201 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00662149 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00657511 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00654513 |
| SORD | sorbitol dehydrogenase | 0.00653813 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00650309 |
| PFDN5 | prefoldin subunit 5 | 0.0064787 |
| SLC25A46 | solute carrier family 25, member 46 | 0.0064624 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00645812 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00645206 |
| TMEM126B | transmembrane protein 126B | 0.00641766 |
| CCK | cholecystokinin | 0.00640422 |
| KLK2 | kallikrein-related peptidase 2 | 0.00639473 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00635105 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | 0.00634768 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00632505 |
| RBM47 | RNA binding motif protein 47 | 0.00632322 |
| TUBA1A | tubulin, alpha 1a | 0.00630826 |
| PRKD3 | protein kinase D3 | 0.00624129 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00621824 |
| NXN | nucleoredoxin | 0.00621713 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.00620056 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00619862 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00617276 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.0061712 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00617005 |
| MATN2 | matrilin 2 | 0.00616269 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00613632 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00613274 |
| MAOB | monoamine oxidase B | 0.00610289 |
| GLO1 | glyoxalase I | 0.00608967 |
| TRAPPC3 | trafficking protein particle complex 3 | 0.00607551 |
| FZD6 | frizzled class receptor 6 | 0.00607074 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0060699 |
| RANBP9 | RAN binding protein 9 | 0.00606804 |
| ATXN1 | ataxin 1 | 0.00606767 |
| CHRDL1 | chordin-like 1 | 0.00605461 |
| TAGLN2 | transgelin 2 | 0.00605157 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00603978 |
| CTSV | cathepsin V | 0.00601461 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00600234 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0059855 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00597614 |
| ESYT1 | extended synaptotagmin-like protein 1 | 0.00597493 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00595121 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00594309 |
| BCHE | butyrylcholinesterase | 0.00591101 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00591083 |
| ORC4 | origin recognition complex, subunit 4 | 0.00590257 |
| FLOT2 | flotillin 2 | 0.00589764 |
| PALLD | palladin, cytoskeletal associated protein | 0.00588613 |
| CAV2 | caveolin 2 | 0.00588339 |
| H1-10 | H1.10 linker histone | 0.00588315 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00586401 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00584527 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00584427 |
| PRR13 | proline rich 13 | 0.00583725 |
| TOR3A | torsin family 3, member A | 0.00583177 |
| ANKRD49 | ankyrin repeat domain 49 | 0.00581777 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00581342 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00580687 |
| SPAG5 | sperm associated antigen 5 | 0.00580524 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00580056 |
| MRTFB | myocardin related transcription factor B | 0.0057914 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | 0.00578523 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00578496 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00578039 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00577297 |
| RWDD1 | RWD domain containing 1 | 0.00577173 |
| MREG | melanoregulin | 0.00576458 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.00575927 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.00574348 |
| EXOSC9 | exosome component 9 | 0.00572905 |
| RAI2 | retinoic acid induced 2 | 0.00570736 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00566286 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00565298 |
| LIPT1 | lipoyltransferase 1 | 0.00563218 |
| MMP11 | matrix metallopeptidase 11 | 0.00563142 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | 0.0056231 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00561946 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.0056186 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00561657 |
| STON1 | stonin 1 | 0.00561552 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.00561317 |
| RAB25 | RAB25, member RAS oncogene family | 0.00559005 |
| ZNF467 | zinc finger protein 467 | 0.00558965 |
| ZNF239 | zinc finger protein 239 | 0.00557737 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00556034 |
| KATNA1 | katanin p60 (ATPase containing) subunit A 1 | 0.00555953 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00555194 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00554283 |
| CD200 | CD200 molecule | 0.00553421 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00552925 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00551884 |
| SERINC5 | serine incorporator 5 | 0.0055048 |
| FAM162A | family with sequence similarity 162, member A | 0.00550132 |
| SNX3 | sorting nexin 3 | 0.00549256 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00547291 |
| KLK3 | kallikrein-related peptidase 3 | 0.00546628 |
| CHKB | choline kinase beta | 0.00545509 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.00545095 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00544307 |
| ERGIC2 | ERGIC and golgi 2 | 0.00544274 |
| ERP29 | endoplasmic reticulum protein 29 | 0.00542228 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00542217 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | 0.00541781 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.00541591 |
| E2F2 | E2F transcription factor 2 | 0.00540937 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00540916 |
| NME7 | NME/NM23 family member 7 | 0.00540548 |
| GDF3 | growth differentiation factor 3 | 0.00540075 |
| SDF2 | stromal cell-derived factor 2 | 0.00539637 |
| CEP70 | centrosomal protein 70kDa | 0.00539061 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00538365 |
| ITM2C | integral membrane protein 2C | 0.00538222 |
| PFKP | phosphofructokinase, platelet | 0.0053515 |
| ACSF2 | acyl-CoA synthetase family member 2 | 0.00534189 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00533807 |
| GAL | galanin/GMAP prepropeptide | 0.00531385 |
| GUK1 | guanylate kinase 1 | 0.00531203 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.00529466 |
| MYO1C | myosin IC | 0.00527803 |
| FGG | fibrinogen gamma chain | 0.00527625 |
| SEPTIN6 | septin 6 | 0.00527422 |
| NELFE | negative elongation factor complex member E | 0.00526712 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00524917 |
| BEND5 | BEN domain containing 5 | 0.00522583 |
| TTC1 | tetratricopeptide repeat domain 1 | 0.00522308 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00521643 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00520458 |
| CLOCK | clock circadian regulator | 0.00520337 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00520003 |
| TMEM8A | transmembrane protein 8A | 0.00519924 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00519772 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00519442 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00519091 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.0051842 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.00518282 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00518175 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00517652 |
| REXO5 | RNA exonuclease 5 | 0.00517509 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00517407 |
| ATG5 | autophagy related 5 | 0.00517227 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00517199 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00517051 |
| GDF11 | growth differentiation factor 11 | 0.0051668 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00516393 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00516003 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00514966 |
| ESD | esterase D | 0.00514325 |
| EMILIN1 | elastin microfibril interfacer 1 | 0.00513828 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00512566 |
| HOXD10 | homeobox D10 | 0.00512409 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | 0.00512175 |
| IRF7 | interferon regulatory factor 7 | 0.00511796 |
| MSX1 | msh homeobox 1 | 0.00511714 |
| CD2AP | CD2-associated protein | 0.00510422 |
| PRKD1 | protein kinase D1 | 0.00509919 |
| ZNF200 | zinc finger protein 200 | 0.00509353 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00509038 |
| UBN1 | ubinuclein 1 | 0.00508505 |
| CDC25C | cell division cycle 25C | 0.00508047 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00507282 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00507244 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00507076 |
| PCNP | PEST proteolytic signal containing nuclear protein | 0.00505835 |
| AEBP1 | AE binding protein 1 | 0.0050476 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | 0.00503666 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.00502932 |
| PYGB | phosphorylase, glycogen; brain | 0.00502848 |
| TFRC | transferrin receptor | 0.00502694 |
| CLGN | calmegin | 0.0050238 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 | 0.00501911 |
| EFCAB11 | EF-hand calcium binding domain 11 | 0.00501477 |
| TEAD4 | TEA domain family member 4 | 0.00501464 |
| RWDD2A | RWD domain containing 2A | 0.00501034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0335364 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0225231 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0161835 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.015372 |
| KRT23 | keratin 23, type I | -0.015239 |
| S100A8 | S100 calcium binding protein A8 | -0.0151409 |
| KRT14 | keratin 14, type I | -0.0146944 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0139547 |
| RB1 | retinoblastoma 1 | -0.0133378 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0131174 |
| MAGEA3 | melanoma antigen family A3 | -0.0127087 |
| DIPK1A | divergent protein kinase domain 1A | -0.0126603 |
| TYMS | thymidylate synthetase | -0.0123915 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0123202 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0123046 |
| RRBP1 | ribosome binding protein 1 | -0.0122573 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.0120594 |
| C1QB | complement component 1, q subcomponent, B chain | -0.0119109 |
| CHGB | chromogranin B | -0.0118071 |
| C3 | complement component 3 | -0.0112725 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.0111632 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.0111598 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.011143 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0111232 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0111105 |
| TMEM230 | transmembrane protein 230 | -0.0110336 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0110174 |
| S100A9 | S100 calcium binding protein A9 | -0.0107348 |
| PADI2 | peptidyl arginine deiminase, type II | -0.0107174 |
| LTF | lactotransferrin | -0.0106295 |
| CRYAB | crystallin, alpha B | -0.0106085 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0105622 |
| KRT17 | keratin 17, type I | -0.0103788 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.0102715 |
| CFB | complement factor B | -0.0102658 |
| PLAT | plasminogen activator, tissue | -0.0101392 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00999966 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00989297 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00983908 |
| OLFM4 | olfactomedin 4 | -0.00980528 |
| TMEM176B | transmembrane protein 176B | -0.00973213 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | -0.00972692 |
| NOP56 | NOP56 ribonucleoprotein | -0.00971851 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00971234 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00956323 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.0095441 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -0.00945015 |
| LCN2 | lipocalin 2 | -0.00943821 |
| PLCB4 | phospholipase C, beta 4 | -0.00937178 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00934273 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00934193 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00933836 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00931187 |
| TAGLN | transgelin | -0.00928933 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00909792 |
| PEG10 | paternally expressed 10 | -0.0090897 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00907344 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00907316 |
| TMEM176A | transmembrane protein 176A | -0.00905373 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00904217 |
| TSPO | translocator protein (18kDa) | -0.00902809 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00898491 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00896764 |
| OXTR | oxytocin receptor | -0.00891786 |
| CD14 | CD14 molecule | -0.0087871 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00877346 |
| CEP170 | centrosomal protein 170kDa | -0.00874703 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00869108 |
| SIRPA | signal-regulatory protein alpha | -0.00867216 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00866934 |
| DACH1 | dachshund family transcription factor 1 | -0.00866674 |
| TLR4 | toll-like receptor 4 | -0.00862101 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00856379 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00855327 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00851325 |
| HBD | hemoglobin, delta | -0.00850651 |
| S100P | S100 calcium binding protein P | -0.00850035 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00847775 |
| MAB21L1 | mab-21-like 1 (C. elegans) | -0.0084038 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00835639 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.00830896 |
| PDGFD | platelet derived growth factor D | -0.00829348 |
| DDRGK1 | DDRGK domain containing 1 | -0.00823313 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00820444 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00819759 |
| MMP7 | matrix metallopeptidase 7 | -0.0081912 |
| LUM | lumican | -0.00818421 |
| AK1 | adenylate kinase 1 | -0.008175 |
| PRNP | prion protein | -0.00817097 |
| KRT7 | keratin 7, type II | -0.00815343 |
| MGAM | maltase-glucoamylase | -0.00812023 |
| ASS1 | argininosuccinate synthase 1 | -0.00809665 |
| PCLAF | PCNA clamp associated factor | -0.00806409 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00806063 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00805644 |
| TMEM260 | transmembrane protein 260 | -0.00799805 |
| CLU | clusterin | -0.00799279 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00798744 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.00794605 |
| S100A12 | S100 calcium binding protein A12 | -0.00794448 |
| PCDH9 | protocadherin 9 | -0.00793529 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00793478 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00793083 |
| GPX2 | glutathione peroxidase 2 | -0.00791878 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00791214 |
| RGS1 | regulator of G-protein signaling 1 | -0.00789535 |
| IL32 | interleukin 32 | -0.00783725 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | -0.00783717 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00783567 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | -0.00781748 |
| TUBB4B | tubulin, beta 4B class IVb | -0.00773588 |
| STAB1 | stabilin 1 | -0.00772374 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -0.00772326 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.00770777 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00767843 |
| RELN | reelin | -0.00756197 |
| CLC | Charcot-Leyden crystal galectin | -0.00755921 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00753832 |
| CD163 | CD163 molecule | -0.00752875 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00752698 |
| CLCA1 | chloride channel accessory 1 | -0.00752673 |
| ASPA | aspartoacylase | -0.00752204 |
| ADM | adrenomedullin | -0.00751972 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00749659 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00743536 |
| MCAM | melanoma cell adhesion molecule | -0.0074124 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00739102 |
| PLBD1 | phospholipase B domain containing 1 | -0.00739013 |
| FGF1 | fibroblast growth factor 1 (acidic) | -0.00735103 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00731263 |
| FAM198B | family with sequence similarity 198, member B | -0.00729903 |
| CNTN1 | contactin 1 | -0.00729218 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00727702 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.0072603 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00722538 |
| PIP | prolactin-induced protein | -0.00722279 |
| COL3A1 | collagen, type III, alpha 1 | -0.00721515 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00721304 |
| CSNK2A1 | casein kinase 2, alpha 1 polypeptide | -0.00719368 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00718999 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00715301 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00713428 |
| SYNM | synemin, intermediate filament protein | -0.00709924 |
| TRIM29 | tripartite motif containing 29 | -0.00709315 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00708788 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.0070757 |
| TLE4 | transducin-like enhancer of split 4 | -0.00705761 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.0070232 |
| TOB2 | transducer of ERBB2, 2 | -0.00701943 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00699958 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00699853 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0069325 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.00692273 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00690621 |
| PLK2 | polo-like kinase 2 | -0.00690279 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | -0.00683776 |
| RIN2 | Ras and Rab interactor 2 | -0.00680195 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00680164 |
| EPS8L2 | EPS8-like 2 | -0.0067949 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -0.00678442 |
| NFASC | neurofascin | -0.00678002 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00676796 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | -0.00675481 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.00675188 |
| FCGBP | Fc fragment of IgG binding protein | -0.00674649 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00673769 |
| IFI44L | interferon-induced protein 44-like | -0.00672378 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 | -0.00670358 |
| CAPN3 | calpain 3, (p94) | -0.00670044 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00669778 |
| POSTN | periostin, osteoblast specific factor | -0.00668828 |
| KIAA0930 | KIAA0930 | -0.00668244 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00667222 |
| PMP22 | peripheral myelin protein 22 | -0.00667075 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.00666639 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00666063 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.006655 |
| SMAD7 | SMAD family member 7 | -0.00664347 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00664113 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00662286 |
| CALR | calreticulin | -0.00660165 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00655848 |
| KLK6 | kallikrein-related peptidase 6 | -0.00654762 |
| CRH | corticotropin releasing hormone | -0.00649303 |
| PFN2 | profilin 2 | -0.00648262 |
| CORO2B | coronin, actin binding protein, 2B | -0.00648228 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00647956 |
| RAB14 | RAB14, member RAS oncogene family | -0.00647868 |
| KIF16B | kinesin family member 16B | -0.0064757 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00646859 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.0064453 |
| KIF5B | kinesin family member 5B | -0.00643291 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00643171 |
| CASD1 | CAS1 domain containing 1 | -0.00642841 |
| C3AR1 | complement component 3a receptor 1 | -0.00640855 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -0.00640325 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00639246 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00638484 |
| AZU1 | azurocidin 1 | -0.00638342 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) | -0.00638109 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -0.00638063 |
| RET | ret proto-oncogene | -0.00637227 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00636407 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00636269 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | -0.00633511 |
| AOC1 | amine oxidase, copper containing 1 | -0.00633041 |
| FBLN2 | fibulin 2 | -0.00632437 |
| LIPG | lipase, endothelial | -0.00632012 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00631092 |
| XPO7 | exportin 7 | -0.00630296 |
| NID2 | nidogen 2 (osteonidogen) | -0.0062988 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00629561 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -0.00629183 |
| PTGDR | prostaglandin D2 receptor (DP) | -0.00629124 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00629053 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00628082 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -0.00627529 |
| EFHD1 | EF-hand domain family, member D1 | -0.00626622 |
| TM6SF1 | transmembrane 6 superfamily member 1 | -0.00626294 |
| ATP10B | ATPase, class V, type 10B | -0.00626049 |
| PLIN1 | perilipin 1 | -0.00624249 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | -0.00623974 |
| REG3A | regenerating islet-derived 3 alpha | -0.00622848 |
| PCBP4 | poly(rC) binding protein 4 | -0.00622115 |
| XAF1 | XIAP associated factor 1 | -0.00621544 |
| CTSZ | cathepsin Z | -0.00621252 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00621071 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.00620646 |
| NNMT | nicotinamide N-methyltransferase | -0.00620526 |
| ZIC1 | Zic family member 1 | -0.00620431 |
| IL7R | interleukin 7 receptor | -0.00620176 |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | -0.0061984 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -0.00619136 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00617617 |
| ELOVL1 | ELOVL fatty acid elongase 1 | -0.00617336 |
| OSBPL1A | oxysterol binding protein-like 1A | -0.00617328 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00616717 |
| SPIN1 | spindlin 1 | -0.00615896 |
| FRMD4B | FERM domain containing 4B | -0.00613559 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00613434 |
| ZNF160 | zinc finger protein 160 | -0.00611817 |
| MCM4 | minichromosome maintenance complex component 4 | -0.0061148 |
| MCOLN1 | mucolipin 1 | -0.0061015 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.00607897 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00606915 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00606366 |
| MMP8 | matrix metallopeptidase 8 | -0.00605223 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00603883 |
