PBK Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PDZ binding kinase|This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 55872)
External Link http://www.ncbi.nlm.nih.gov/gene/55872
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Genes

43 interacting proteins for PBK from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APC adenomatous polyposis coli
ARAF A-Raf proto-oncogene, serine/threonine kinase
CCNB1 cyclin B1
CDK1 cyclin-dependent kinase 1
CEP126 centrosomal protein 126kDa
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTNBP2NL CTTNBP2 N-terminal like
DLG1 discs, large homolog 1 (Drosophila)
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
FGFR1OP2 FGFR1 oncogene partner 2
FKBP15 FK506 binding protein 15, 133kDa
FMNL1 formin-like 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPS2 G protein pathway suppressor 2
GPSM2 G-protein signaling modulator 2
H2AFX H2A histone family, member X
HIST1H3B histone cluster 1, H3b
KIAA1671 KIAA1671
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LRRC47 leucine rich repeat containing 47
MBP myelin basic protein
MOB4 MOB family member 4, phocein
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
PARVG parvin, gamma
PRC1 protein regulator of cytokinesis 1
PRDX1 peroxiredoxin 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SIKE1 suppressor of IKBKE 1
SLMAP sarcolemma associated protein
SMAD4 SMAD family member 4
STK24 serine/threonine kinase 24
STRIP1 striatin interacting protein 1
STRN striatin, calmodulin binding protein
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
TERT telomerase reverse transcriptase
TP53 tumor protein p53
TRIM37 tripartite motif containing 37
UBC ubiquitin C
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1