PBX3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description pre-B-cell leukemia homeobox 3| (NCBI Entrez Gene Database, 5090)
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Genes

341 genes differentially expressed following the PBX3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.66666
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.66666
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.66666
NPAP1 nuclear pore associated protein 1 2.66666
FBXL8 F-box and leucine-rich repeat protein 8 2.66666
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.66666
HCRTR1 hypocretin (orexin) receptor 1 2.66666
TMEM244 transmembrane protein 244 2.66666
GPR151 G protein-coupled receptor 151 2.66666
RIMBP2 RIMS binding protein 2 2.66666
CCNB3 cyclin B3 2.66666
HRH1 histamine receptor H1 2.66666
GJA5 gap junction protein, alpha 5, 40kDa 2.66666
ATP13A4 ATPase type 13A4 2.66666
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.66666
PVRIG poliovirus receptor related immunoglobulin domain containing 2.66666
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 2.66666
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 2.66666
ZNF99 zinc finger protein 99 2.66666
SLC22A10 solute carrier family 22, member 10 2.66666
ANGPT2 angiopoietin 2 2.66666
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.66666
SMOC1 SPARC related modular calcium binding 1 2.66666
ATG12 autophagy related 12 2.66666
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.66666
MAGED4 melanoma antigen family D4 2.66666
PNOC prepronociceptin 2.66666
GPR101 G protein-coupled receptor 101 2.66666
KRT72 keratin 72, type II 2.66666
BMP3 bone morphogenetic protein 3 2.66666
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 2.66666
C2ORF78 chromosome 2 open reading frame 78 2.66666
ERAP2 endoplasmic reticulum aminopeptidase 2 2.66666
FGF7 fibroblast growth factor 7 2.66666
CCDC83 coiled-coil domain containing 83 2.66666
FAM229A family with sequence similarity 229, member A 2.66666
CELA1 chymotrypsin-like elastase family, member 1 2.66666
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 2.66666
OLIG3 oligodendrocyte transcription factor 3 2.66666
FOLR3 folate receptor 3 (gamma) 2.66666
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.66666
CIITA class II, major histocompatibility complex, transactivator 2.66666
FBLN7 fibulin 7 2.66666
REN renin 2.66666
ADGB androglobin 2.66666
C9ORF152 chromosome 9 open reading frame 152 2.66666
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.66666
WFDC11 WAP four-disulfide core domain 11 2.66666
PCDHB13 protocadherin beta 13 2.66666
LOC124906892 uncharacterized LOC124906892 2.66666
CLDN12 claudin 12 2.66666
PLN phospholamban 2.66666
DUSP8 dual specificity phosphatase 8 2.66666
STMN4 stathmin-like 4 2.66666
SPRR2B small proline-rich protein 2B 2.66666
PKD2L1 polycystic kidney disease 2-like 1 2.66666
TMPRSS4 transmembrane protease, serine 4 2.66666
TEDDM1 transmembrane epididymal protein 1 2.66666
TTR transthyretin 2.66666
DOK2 docking protein 2, 56kDa 2.66666
GIPC3 GIPC PDZ domain containing family, member 3 2.66666
ERVW-1 endogenous retrovirus group W, member 1 2.66666
OR2I1 olfactory receptor family 2 subfamily I member 1 (gene/pseudogene) 2.66666
SPEGNB SPEG neighbor 2.66666
THSD8 thrombospondin type 1 domain containing 8 2.66666
NOTCH2NLB notch 2 N-terminal like B 2.66666
LOC124903372 uncharacterized LOC124903372 2.66666
ACP7 acid phosphatase 7, tartrate resistant (putative) 2.66666
H2BC3 H2B clustered histone 3 2.66666
ERFE erythroferrone 2.66666
PMIS2 PMIS2 transmembrane protein 2.66666
RAB6D RAB6D, member RAS oncogene family 2.66666
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 2.66666
GATA4 GATA binding protein 4 2.66666
C1QL2 complement component 1, q subcomponent-like 2 2.66666
TLR6 toll-like receptor 6 2.66666
IL6 interleukin 6 2.66666
ING4 inhibitor of growth family, member 4 2.66666
NPIPB9 nuclear pore complex interacting protein family, member B9 2.66666
IDO2 indoleamine 2,3-dioxygenase 2 2.66666
CALCA calcitonin-related polypeptide alpha 2.66666
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.66666
THPO thrombopoietin 2.66666
FAM43B family with sequence similarity 43, member B 2.66666
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.66666
CDKN2A cyclin-dependent kinase inhibitor 2A 2.66666
PRDM6 PR domain containing 6 2.66666
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.66666
MOV10L1 Mov10 RISC complex RNA helicase like 1 2.66666
PXDC1 PX domain containing 1 2.66666
NPIPB8 nuclear pore complex interacting protein family, member B8 2.66666
FGFBP2 fibroblast growth factor binding protein 2 2.66666
IL1R1 interleukin 1 receptor, type I 2.66666
VCX3A variable charge, X-linked 3A 2.66666
SAA1 serum amyloid A1 2.66666
CELA2A chymotrypsin-like elastase family, member 2A 2.66666
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.66666
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.66666
PHOX2A paired-like homeobox 2a 2.66666
EFCAB3 EF-hand calcium binding domain 3 2.66666
C9ORF64 chromosome 9 open reading frame 64 2.66666
CYSLTR1 cysteinyl leukotriene receptor 1 2.66666
CDHR4 cadherin-related family member 4 2.66666
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.66666
WFDC9 WAP four-disulfide core domain 9 2.66666
TDRD10 tudor domain containing 10 2.66666
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 2.66666
OR56A3 olfactory receptor, family 56, subfamily A, member 3 2.66666
UBXN10 UBX domain protein 10 2.66666
GFI1B growth factor independent 1B transcription repressor 2.66666
CSF1R colony stimulating factor 1 receptor 2.66666
CST7 cystatin F (leukocystatin) 2.66666
FLRT3 fibronectin leucine rich transmembrane protein 3 2.66666
CH25H cholesterol 25-hydroxylase 2.66666
HAMP hepcidin antimicrobial peptide 2.66666
RAD21L1 RAD21-like 1 (S. pombe) 2.66666
NOG noggin 2.66666
TPSB2 tryptase beta 2 (gene/pseudogene) 2.66666
NIPAL4 NIPA-like domain containing 4 2.66666
KIAA1210 KIAA1210 2.66666
RBM24 RNA binding motif protein 24 2.66666
FBXO47 F-box protein 47 2.66666
TF transferrin 2.66666
PCDHA12 protocadherin alpha 12 2.66666
FAM135B family with sequence similarity 135, member B 2.66666
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.66666
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.66666
ANKRD55 ankyrin repeat domain 55 2.66666
DLX2 distal-less homeobox 2 2.66666
LRRK2 leucine-rich repeat kinase 2 2.66666
CDH10 cadherin 10, type 2 (T2-cadherin) 2.66666
CGB2 chorionic gonadotropin, beta polypeptide 2 2.66666
INSM1 insulinoma-associated 1 2.66666
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 2.66666
ISL1 ISL LIM homeobox 1 2.66666
NT5C1B 5'-nucleotidase, cytosolic IB 2.66666
SLC22A24 solute carrier family 22, member 24 2.66666
PDZRN4 PDZ domain containing ring finger 4 2.66666
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.66666
NEUROD1 neuronal differentiation 1 2.66666
TTC24 tetratricopeptide repeat domain 24 2.66666
RGR retinal G protein coupled receptor 2.66666
ACKR2 atypical chemokine receptor 2 2.66666
FKBP1C FK506 binding protein 1C 2.66666
TMIGD2 transmembrane and immunoglobulin domain containing 2 2.66666
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.66666
ETV3L ets variant 3-like 2.66666
TOPAZ1 testis and ovary specific PAZ domain containing 1 2.66666
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.66666
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.66666
FADS6 fatty acid desaturase 6 2.66666
CHRDL2 chordin-like 2 2.66666
TNMD tenomodulin 2.66666
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 2.66666
OR52N2 olfactory receptor, family 52, subfamily N, member 2 2.66666
ZNF835 zinc finger protein 835 2.66666
CETP cholesteryl ester transfer protein, plasma 2.66666
C22ORF31 chromosome 22 open reading frame 31 2.66666
CHRM4 cholinergic receptor, muscarinic 4 2.66666
SMYD1 SET and MYND domain containing 1 2.66666
OPALIN oligodendrocytic myelin paranodal and inner loop protein 2.66666
MEIS1 Meis homeobox 1 2.66666
RASA4 RAS p21 protein activator 4 2.66666
TIGIT T cell immunoreceptor with Ig and ITIM domains 2.66666
CD8B CD8b molecule 2.66666
FAIM2 Fas apoptotic inhibitory molecule 2 2.66666
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.66666
HLA-DMB major histocompatibility complex, class II, DM beta 2.66666
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 2.66666
APOF apolipoprotein F 2.66666
KRT10 keratin 10, type I 2.66666
KRT17 keratin 17, type I 2.66666
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 2.66666
FEZF2 FEZ family zinc finger 2 2.66666
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.66666
ENPEP glutamyl aminopeptidase (aminopeptidase A) 2.6531
PMPCB peptidase (mitochondrial processing) beta 2.6531
ZBTB11 zinc finger and BTB domain containing 11 2.6531
RBM46 RNA binding motif protein 46 2.61209
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 2.61209
PLSCR1 phospholipid scramblase 1 2.59141
MYB v-myb avian myeloblastosis viral oncogene homolog 2.59141
MAP7D3 MAP7 domain containing 3 2.5738
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 2.47926
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 2.45156
COMMD4 COMM domain containing 4 2.43967
CCR5AS CCR5 antisense RNA 2.43434
LGALS4 lectin, galactoside-binding, soluble, 4 2.40759
SUSD6 sushi domain containing 6 2.40744
RPS3 ribosomal protein S3 2.38872
ITM2B integral membrane protein 2B 2.38872
GRAMD1B GRAM domain containing 1B 2.38872
CYB5D1 cytochrome b5 domain containing 1 2.36087
MEMO1 mediator of cell motility 1 2.35497
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.31967
EGFL7 EGF-like-domain, multiple 7 2.29493
ASB8 ankyrin repeat and SOCS box containing 8 2.28927
SND1 staphylococcal nuclease and tudor domain containing 1 2.28893
AGK acylglycerol kinase 2.28796
SEC24B SEC24 family member B 2.28611
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 2.28271
PTGFRN prostaglandin F2 receptor inhibitor 2.27897
FAM76A family with sequence similarity 76, member A 2.27897
AADAT aminoadipate aminotransferase 2.27897
EXOSC9 exosome component 9 2.2565
JOSD1 Josephin domain containing 1 2.24634
TRIM25 tripartite motif containing 25 2.24634
CASP6 caspase 6, apoptosis-related cysteine peptidase 2.2428
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 2.23637
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.229
FNDC4 fibronectin type III domain containing 4 2.20012
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.18232
SLBP stem-loop binding protein 2.17926
WBP2 WW domain binding protein 2 2.17907
SKIC3 SKI3 subunit of superkiller complex 2.16518
CXCL3 chemokine (C-X-C motif) ligand 3 2.16246
SHANK2 SH3 and multiple ankyrin repeat domains 2 2.15392
FAM13A family with sequence similarity 13, member A 2.15109
ATP9B ATPase, class II, type 9B 2.1293
BDNF brain-derived neurotrophic factor 2.12559
ZC3HC1 zinc finger, C3HC-type containing 1 2.09318
CLCN3 chloride channel, voltage-sensitive 3 2.08278
C1ORF198 chromosome 1 open reading frame 198 2.0769
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.06606
CYFIP2 cytoplasmic FMR1 interacting protein 2 2.0607
CNIH2 cornichon family AMPA receptor auxiliary protein 2 2.0607
ZNF580 zinc finger protein 580 2.05784
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.05678
ZNF24 zinc finger protein 24 2.0446
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 2.03796
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 2.03605
ERLIN2 ER lipid raft associated 2 2.02397
MXD4 MAX dimerization protein 4 2.01716
RUSC2 RUN and SH3 domain containing 2 2.01716
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 2.01076

decreased expression

Symbol Name Standardized Value
VSTM5 V-set and transmembrane domain containing 5 -2.66666
ZNF527 zinc finger protein 527 -2.66666
SALL1 spalt-like transcription factor 1 -2.66666
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.66666
STOML2 stomatin (EPB72)-like 2 -2.66666
CREG1 cellular repressor of E1A-stimulated genes 1 -2.66666
PI15 peptidase inhibitor 15 -2.66666
PBX3 pre-B-cell leukemia homeobox 3 -2.66666
LIN28B lin-28 homolog B (C. elegans) -2.66666
SAXO5 stabilizer of axonemal microtubules 5 -2.66666
MMP26 matrix metallopeptidase 26 -2.66666
ZNF845 zinc finger protein 845 -2.65603
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -2.6531
LAMP3 lysosomal-associated membrane protein 3 -2.6531
OXER1 oxoeicosanoid (OXE) receptor 1 -2.6531
MEIOB meiosis specific with OB domains -2.6531
LECT2 leukocyte cell-derived chemotaxin 2 -2.6531
PRKCE protein kinase C, epsilon -2.6531
SIM2 single-minded family bHLH transcription factor 2 -2.6531
MSC musculin -2.6531
ADGRE3 adhesion G protein-coupled receptor E3 -2.6531
ARHGAP36 Rho GTPase activating protein 36 -2.6531
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -2.6531
NWD1 NACHT and WD repeat domain containing 1 -2.6531
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 -2.6531
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 -2.6531
C1ORF146 chromosome 1 open reading frame 146 -2.6531
CCR6 chemokine (C-C motif) receptor 6 -2.6531
KANK4 KN motif and ankyrin repeat domains 4 -2.6531
CCDC78 coiled-coil domain containing 78 -2.6531
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 -2.6531
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) -2.6531
NLRC3 NLR family, CARD domain containing 3 -2.6531
H3C14 H3 clustered histone 14 -2.6531
SPMIP3 sperm microtubule inner protein 3 -2.6531
LY6G6D lymphocyte antigen 6 complex, locus G6D -2.6531
IRX4 iroquois homeobox 4 -2.6531
HLA-G major histocompatibility complex, class I, G -2.6531
NR1D1 nuclear receptor subfamily 1, group D, member 1 -2.59756
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -2.59756
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -2.59756
CCDC86 coiled-coil domain containing 86 -2.59141
TMEM223 transmembrane protein 223 -2.59036
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.56795
WDR70 WD repeat domain 70 -2.55762
LINGO1 leucine rich repeat and Ig domain containing 1 -2.47313
METTL17 methyltransferase like 17 -2.45428
PARD6A par-6 family cell polarity regulator alpha -2.43434
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -2.41465
ANO6 anoctamin 6 -2.38795
AP3B1 adaptor-related protein complex 3, beta 1 subunit -2.38113
ANO7 anoctamin 7 -2.34872
TSHR thyroid stimulating hormone receptor -2.3465
RSPO2 R-spondin 2 -2.3465
PTGES3L prostaglandin E synthase 3 (cytosolic)-like -2.3465
FICD FIC domain containing -2.33862
ZNF658 zinc finger protein 658 -2.3382
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa -2.32196
C17ORF58 chromosome 17 open reading frame 58 -2.31967
UNKL unkempt family zinc finger-like -2.29905
MIMS1 mitochondrial inner membrane scaffold 1 -2.29905
TTK TTK protein kinase -2.28271
ORAI1 ORAI calcium release-activated calcium modulator 1 -2.28251
SWSAP1 SWIM-type zinc finger 7 associated protein 1 -2.27897
BOD1L1 biorientation of chromosomes in cell division 1-like 1 -2.2783
PLAAT1 phospholipase A and acyltransferase 1 -2.27108
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.25697
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30 -2.24687
SLC35D4 solute carrier family 35 member D4 -2.20012
UBXN6 UBX domain protein 6 -2.20012
SURF1 surfeit 1 -2.17683
C22ORF23 chromosome 22 open reading frame 23 -2.16518
TMEM185A transmembrane protein 185A -2.16518
SNX9 sorting nexin 9 -2.15109
R3HDM2 R3H domain containing 2 -2.15109
NIBAN1 niban apoptosis regulator 1 -2.14592
CREB5 cAMP responsive element binding protein 5 -2.14592
USP35 ubiquitin specific peptidase 35 -2.14259
FBXO36 F-box protein 36 -2.1384
WDR81 WD repeat domain 81 -2.12559
FHIP2B FHF complex subunit HOOK interacting protein 2B -2.12559
MIDN midnolin -2.11157
FASTKD3 FAST kinase domains 3 -2.09318
OSGEP O-sialoglycoprotein endopeptidase -2.08943
DOK5 docking protein 5 -2.08278
CCDC7 coiled-coil domain containing 7 -2.08278
BEND7 BEN domain containing 7 -2.07621
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 -2.07606
TMTC3 transmembrane and tetratricopeptide repeat containing 3 -2.07383
DMD dystrophin -2.07263
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.0666
SLC16A6 solute carrier family 16, member 6 -2.0666
RPAIN RPA interacting protein -2.06372
WDR3 WD repeat domain 3 -2.05527
RAVER2 ribonucleoprotein, PTB-binding 2 -2.05527
GLMN glomulin, FKBP associated protein -2.04558
CAV2 caveolin 2 -2.0452
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.04414
HFE hemochromatosis -2.04414
ITGB4 integrin, beta 4 -2.04414
IL17RC interleukin 17 receptor C -2.04414
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.04414
CALML4 calmodulin-like 4 -2.03605
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -2.0359
RGS5 regulator of G-protein signaling 5 -2.03534
METTL21A methyltransferase like 21A -2.02449