| Dataset | Sanger Dependency Map Cancer Cell Line Proteomics |
| Category | proteomics |
| Type | cell line |
| Description | Human prostate carcinoma cell line; established from the bone marrow metastasis isolated post-mortem from a 62-year-old Caucasian man with grade IV prostate cancer, poorly differentiated adenocarcinoma, after androgen suppression therapy; described to form tumors in nude mice, to grow in soft agar, and to be unresponsive to androgen treatment. (Experimental Factor Ontology, EFO_0002074) |
| External Link | https://cellmodelpassports.sanger.ac.uk/passports/SIDM00088 |
| Similar Terms | |
| Downloads & Tools |
196 proteins associated with the cell line PC-3 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.
| Symbol | Name |
|---|---|
| ACSF3 | acyl-CoA synthetase family member 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANXA7 | annexin A7 |
| AP1M1 | adaptor-related protein complex 1, mu 1 subunit |
| BAD | BCL2-associated agonist of cell death |
| BCL2L1 | BCL2-like 1 |
| BMS1 | BMS1 ribosome biogenesis factor |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCDC115 | coiled-coil domain containing 115 |
| CLPP | caseinolytic mitochondrial matrix peptidase proteolytic subunit |
| COL13A1 | collagen, type XIII, alpha 1 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CUL2 | cullin 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| EIF1B | eukaryotic translation initiation factor 1B |
| EP400 | E1A binding protein p400 |
| EXD2 | exonuclease 3'-5' domain containing 2 |
| EXOC2 | exocyst complex component 2 |
| FBXO11 | F-box protein 11 |
| FH | fumarate hydratase |
| FOSL1 | FOS-like antigen 1 |
| FUNDC2 | FUN14 domain containing 2 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GRPEL2 | GrpE-like 2, mitochondrial (E. coli) |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| HAX1 | HCLS1 associated protein X-1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IQCA1 | IQ motif containing with AAA domain 1 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT5 | keratin 5, type II |
| LACTB2 | lactamase, beta 2 |
| LDLR | low density lipoprotein receptor |
| LXN | latexin |
| LYPLAL1 | lysophospholipase-like 1 |
| MAX | MYC associated factor X |
| MBLAC2 | metallo-beta-lactamase domain containing 2 |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MRPS6 | mitochondrial ribosomal protein S6 |
| MTIF2 | mitochondrial translational initiation factor 2 |
| NBR1 | neighbor of BRCA1 gene 1 |
| NCOR2 | nuclear receptor corepressor 2 |
| NOP14 | NOP14 nucleolar protein |
| NRP1 | neuropilin 1 |
| PET100 | PET100 homolog (S. cerevisiae) |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa |
| PPAN | peter pan homolog (Drosophila) |
| PPIF | peptidylprolyl isomerase F |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PRR12 | proline rich 12 |
| RAF1 | Raf-1 proto-oncogene, serine/threonine kinase |
| RBM25 | RNA binding motif protein 25 |
| RBM4B | RNA binding motif protein 4B |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP15 | ribosomal RNA processing 15 homolog (S. cerevisiae) |
| RRP36 | ribosomal RNA processing 36 homolog (S. cerevisiae) |
| RWDD1 | RWD domain containing 1 |
| RXRB | retinoid X receptor, beta |
| SCRIB | scribbled planar cell polarity protein |
| SEC24C | SEC24 family member C |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SON | SON DNA binding protein |
| SPRYD4 | SPRY domain containing 4 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| SYNJ2BP | synaptojanin 2 binding protein |
| TAOK3 | TAO kinase 3 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIMMDC1 | translocase of inner mitochondrial membrane domain containing 1 |
| TMEM199 | transmembrane protein 199 |
| TMSB4Y | thymosin beta 4, Y-linked |
| TMX1 | thioredoxin-related transmembrane protein 1 |
| USP36 | ubiquitin specific peptidase 36 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VCL | vinculin |
| VDAC2 | voltage-dependent anion channel 2 |
| VTI1B | vesicle transport through interaction with t-SNAREs 1B |
| WDR46 | WD repeat domain 46 |
| ZDHHC5 | zinc finger, DHHC-type containing 5 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| ACO1 | aconitase 1, soluble |
| ADAM1A | ADAM metallopeptidase domain 1A (pseudogene) |
| ADD3 | adducin 3 (gamma) |
| ARHGAP21 | Rho GTPase activating protein 21 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) |
| BLM | Bloom syndrome, RecQ helicase-like |
| BLMH | bleomycin hydrolase |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CASP14 | caspase 14, apoptosis-related cysteine peptidase |
| CCDC134 | coiled-coil domain containing 134 |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL12A1 | collagen, type XII, alpha 1 |
| CXXC1 | CXXC finger protein 1 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B |
| DENND4C | DENN/MADD domain containing 4C |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| DST | dystonin |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FKBP15 | FK506 binding protein 15, 133kDa |
| FRA1C | fragile site, aphidicolin type, common, fra(1)(p31.2) |
| FTO | fat mass and obesity associated |
| GALK2 | galactokinase 2 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| GYS1 | glycogen synthase 1 (muscle) |
| HABP4 | hyaluronan binding protein 4 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI35 | interferon-induced protein 35 |
| KIAA2013 | KIAA2013 |
| KMT2C | lysine (K)-specific methyltransferase 2C |
| LOC105369582 | uncharacterized LOC105369582 |
| LOC105376613 | uncharacterized LOC105376613 |
| LYPLA1 | lysophospholipase I |
| M6PR | mannose-6-phosphate receptor (cation dependent) |
| MAP2 | microtubule-associated protein 2 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MED30 | mediator complex subunit 30 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MORC4 | MORC family CW-type zinc finger 4 |
| MSTO1 | misato 1, mitochondrial distribution and morphology regulator |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 |
| NAT14 | N-acetyltransferase 14 (GCN5-related, putative) |
| NCBP2 | nuclear cap binding protein subunit 2, 20kDa |
| NLN | neurolysin (metallopeptidase M3 family) |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 |
| PCBP3 | poly(rC) binding protein 3 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PITPNA | phosphatidylinositol transfer protein, alpha |
| PITX1 | paired-like homeodomain 1 |
| PLD2 | phospholipase D2 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PRKCI | protein kinase C, iota |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| PRR11 | proline rich 11 |
| PRRC2B | proline-rich coiled-coil 2B |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTAR1 | protein prenyltransferase alpha subunit repeat containing 1 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| SACK1F | scaffolding CK1 anchoring protein F |
| SCLY | selenocysteine lyase |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) |
| SETD3 | SET domain containing 3 |
| SIRT2 | sirtuin 2 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 |
| SORT1 | sortilin 1 |
| STRBP | spermatid perinuclear RNA binding protein |
| THEM4 | thioesterase superfamily member 4 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRBV7-1 | T cell receptor beta variable 7-1 (non-functional) |
| TUBA8 | tubulin, alpha 8 |
| TUBB4A | tubulin, beta 4A class IVa |
| UBA5 | ubiquitin-like modifier activating enzyme 5 |
| UBAP2 | ubiquitin associated protein 2 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 |
| UVRAG | UV radiation resistance associated |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 |
| VPS25 | vacuolar protein sorting 25 homolog (S. cerevisiae) |
| WDR91 | WD repeat domain 91 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZKSCAN2 | zinc finger with KRAB and SCAN domains 2 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF146 | zinc finger protein 146 |
