| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | propionyl CoA carboxylase, alpha polypeptide|The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 5095) |
| External Link | https://ncbi.nlm.nih.gov/gene/5095 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PCCA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | 0.017461 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0147458 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.014281 |
| E2F2 | E2F transcription factor 2 | 0.0121118 |
| MAP7 | microtubule-associated protein 7 | 0.0118744 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.011814 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0113172 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0109532 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.0102757 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0102417 |
| BCHE | butyrylcholinesterase | 0.00993096 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00971123 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00966477 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00961094 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00937414 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00934436 |
| PRAME | preferentially expressed antigen in melanoma | 0.00928907 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00920387 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00916968 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00889442 |
| DST | dystonin | 0.00880956 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.00879614 |
| KLK11 | kallikrein-related peptidase 11 | 0.00872873 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00870978 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00868999 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00860087 |
| CD163 | CD163 molecule | 0.00851356 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00851174 |
| RB1 | retinoblastoma 1 | 0.00847205 |
| BAG2 | BCL2-associated athanogene 2 | 0.00841038 |
| CPM | carboxypeptidase M | 0.00840717 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00839812 |
| ASPN | asporin | 0.00835466 |
| MX1 | MX dynamin-like GTPase 1 | 0.00834872 |
| IL1R1 | interleukin 1 receptor, type I | 0.00831004 |
| PLA1A | phospholipase A1 member A | 0.00821375 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00815118 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0080944 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00798488 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | 0.00798044 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00795631 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00793521 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00780378 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00779457 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00776731 |
| TGM2 | transglutaminase 2 | 0.00774513 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00770503 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00767101 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00757453 |
| LAMA4 | laminin, alpha 4 | 0.00756252 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00755326 |
| SUSD6 | sushi domain containing 6 | 0.00750732 |
| TWF1 | twinfilin actin binding protein 1 | 0.00750475 |
| CFH | complement factor H | 0.00745893 |
| AEBP1 | AE binding protein 1 | 0.00732143 |
| CDK17 | cyclin-dependent kinase 17 | 0.00731766 |
| IRS2 | insulin receptor substrate 2 | 0.00727372 |
| SMTN | smoothelin | 0.00726683 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00721015 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00720995 |
| TSPYL5 | TSPY-like 5 | 0.00720764 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00719997 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00714696 |
| GPX2 | glutathione peroxidase 2 | 0.00713213 |
| ZIC1 | Zic family member 1 | 0.00713034 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00709945 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00708531 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00705417 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.00699859 |
| NID2 | nidogen 2 (osteonidogen) | 0.00698133 |
| RNF144A | ring finger protein 144A | 0.00693735 |
| PCDH9 | protocadherin 9 | 0.00692542 |
| CLGN | calmegin | 0.00678862 |
| KLK10 | kallikrein-related peptidase 10 | 0.0067122 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.00668883 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00664263 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00663995 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.00661457 |
| CES1 | carboxylesterase 1 | 0.00657275 |
| AREG | amphiregulin | 0.00657009 |
| F12 | coagulation factor XII (Hageman factor) | 0.00653455 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00653264 |
| MAGED1 | melanoma antigen family D1 | 0.00650507 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00644956 |
| CRP | C-reactive protein, pentraxin-related | 0.00643767 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00643569 |
| PLCL2 | phospholipase C-like 2 | 0.00642239 |
| AK1 | adenylate kinase 1 | 0.00642127 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00641126 |
| PFN2 | profilin 2 | 0.00634737 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00633739 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00630699 |
| PRR7 | proline rich 7 (synaptic) | 0.00628328 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.00628148 |
| NAV3 | neuron navigator 3 | 0.00625629 |
| WWC3 | WWC family member 3 | 0.00623229 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00623057 |
| GSK3B | glycogen synthase kinase 3 beta | 0.00620416 |
| MGP | matrix Gla protein | 0.00619316 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00617067 |
| MFAP2 | microfibrillar-associated protein 2 | 0.0061098 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00609004 |
| FGB | fibrinogen beta chain | 0.00608671 |
| EFNB2 | ephrin-B2 | 0.00607739 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00607348 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00606509 |
| EFNA1 | ephrin-A1 | 0.00606229 |
| RRAGD | Ras-related GTP binding D | 0.00605535 |
| EDNRA | endothelin receptor type A | 0.00598255 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00594874 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0059422 |
| SPAG6 | sperm associated antigen 6 | 0.00593311 |
| TCF4 | transcription factor 4 | 0.0059006 |
| MT1M | metallothionein 1M | 0.0058921 |
| RGS3 | regulator of G-protein signaling 3 | 0.00587888 |
| CBX6 | chromobox homolog 6 | 0.00587852 |
| ABHD2 | abhydrolase domain containing 2 | 0.00587682 |
| WSB2 | WD repeat and SOCS box containing 2 | 0.0058658 |
| GPR137B | G protein-coupled receptor 137B | 0.00586043 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00585203 |
| FMO3 | flavin containing monooxygenase 3 | 0.00584718 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00582923 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00582906 |
| DCN | decorin | 0.00579723 |
| SMAD2 | SMAD family member 2 | 0.00577745 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00577694 |
| PCBP4 | poly(rC) binding protein 4 | 0.00577461 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00576096 |
| PCDH17 | protocadherin 17 | 0.00575645 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00571936 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0057154 |
| ICA1 | islet cell autoantigen 1, 69kDa | 0.00569361 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00568973 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00568835 |
| BBX | bobby sox homolog (Drosophila) | 0.00568148 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.00566739 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00566375 |
| TMEM255A | transmembrane protein 255A | 0.00566254 |
| PFKM | phosphofructokinase, muscle | 0.00566096 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00564144 |
| GSN | gelsolin | 0.00562218 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00559973 |
| UBL3 | ubiquitin-like 3 | 0.00559824 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00558888 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00558427 |
| STK26 | serine/threonine protein kinase 26 | 0.00557704 |
| ZNF91 | zinc finger protein 91 | 0.00555852 |
| SYNM | synemin, intermediate filament protein | 0.00555705 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00554272 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.00552426 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.00551501 |
| AUTS2 | autism susceptibility candidate 2 | 0.00550506 |
| FGA | fibrinogen alpha chain | 0.0054982 |
| MEOX2 | mesenchyme homeobox 2 | 0.00549684 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00549479 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00548858 |
| LUM | lumican | 0.00546931 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.00546459 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00544058 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00543173 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.00542235 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00541797 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 0.00540957 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00539573 |
| GDF15 | growth differentiation factor 15 | 0.00537995 |
| EPHB3 | EPH receptor B3 | 0.00537119 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00535974 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00534775 |
| MFAP5 | microfibrillar associated protein 5 | 0.00534207 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00533355 |
| HP | haptoglobin | 0.00532407 |
| PDE10A | phosphodiesterase 10A | 0.00532185 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00532069 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00530136 |
| REPIN1 | replication initiator 1 | 0.00529886 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00528737 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0052863 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00528247 |
| KLHL24 | kelch-like family member 24 | 0.00527016 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 | 0.00526264 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00525787 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.00524437 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00523682 |
| RAI14 | retinoic acid induced 14 | 0.00523591 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00523253 |
| CNN1 | calponin 1, basic, smooth muscle | 0.0052293 |
| DCX | doublecortin | 0.00521847 |
| DCT | dopachrome tautomerase | 0.00521748 |
| COL10A1 | collagen, type X, alpha 1 | 0.00521629 |
| PBK | PDZ binding kinase | 0.00520927 |
| PENK | proenkephalin | 0.00520779 |
| OSR2 | odd-skipped related transciption factor 2 | 0.00520615 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00520218 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00520201 |
| LMNA | lamin A/C | 0.00518165 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00517614 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.00516914 |
| CCNO | cyclin O | 0.00516263 |
| CFHR2 | complement factor H-related 2 | 0.00516115 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00515581 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00515379 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.00515324 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.0051452 |
| GPATCH8 | G patch domain containing 8 | 0.00514097 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0051334 |
| PNMA8A | PNMA family member 8A | 0.00512552 |
| KLHDC10 | kelch domain containing 10 | 0.00512384 |
| FILIP1L | filamin A interacting protein 1-like | 0.00512116 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.00511934 |
| NCALD | neurocalcin delta | 0.00511449 |
| STX4 | syntaxin 4 | 0.00511221 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00510916 |
| APOC3 | apolipoprotein C-III | 0.00510265 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.00510046 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00509599 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00507791 |
| MMP3 | matrix metallopeptidase 3 | 0.00507478 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00507406 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00506664 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.00506152 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00505991 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00505234 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.00504512 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00503869 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 0.00502015 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00501951 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00501629 |
| FGL1 | fibrinogen-like 1 | 0.00500477 |
| SVIL | supervillin | 0.00499799 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00498867 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | 0.00498486 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00496914 |
| CLIC5 | chloride intracellular channel 5 | 0.00494702 |
| PLXDC1 | plexin domain containing 1 | 0.00493271 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.004926 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00492185 |
| KIAA0125 | KIAA0125 | 0.00491719 |
| TCF12 | transcription factor 12 | 0.00491041 |
| XYLT1 | xylosyltransferase I | 0.00490994 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00489975 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.00488721 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00487502 |
| GPM6B | glycoprotein M6B | 0.00487288 |
| APOD | apolipoprotein D | 0.00486914 |
| IL6 | interleukin 6 | 0.00485626 |
| GPR161 | G protein-coupled receptor 161 | 0.00485368 |
| SDC3 | syndecan 3 | 0.00484922 |
| DCHS1 | dachsous cadherin-related 1 | 0.00484639 |
| EGFL6 | EGF-like-domain, multiple 6 | 0.0048451 |
| TAC1 | tachykinin, precursor 1 | 0.004844 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | -0.0161701 |
| SIRT3 | sirtuin 3 | -0.0147156 |
| CSTA | cystatin A (stefin A) | -0.0143155 |
| LTF | lactotransferrin | -0.0139893 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0139295 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0130257 |
| ADM | adrenomedullin | -0.0126915 |
| LYZ | lysozyme | -0.0125516 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.0122593 |
| CA2 | carbonic anhydrase II | -0.0121652 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.012088 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0120355 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0115898 |
| PCNA | proliferating cell nuclear antigen | -0.01148 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0113874 |
| S100A7 | S100 calcium binding protein A7 | -0.0113761 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0113552 |
| S100A9 | S100 calcium binding protein A9 | -0.0110104 |
| KRT7 | keratin 7, type II | -0.0109712 |
| CLDN10 | claudin 10 | -0.0108886 |
| MARCKSL1 | MARCKS-like 1 | -0.0108317 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.0107434 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0107286 |
| TPM4 | tropomyosin 4 | -0.0101978 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0101276 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00972583 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00960553 |
| S100P | S100 calcium binding protein P | -0.00960196 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.009473 |
| KYNU | kynureninase | -0.00945413 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00920021 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00912725 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00889959 |
| BEX1 | brain expressed, X-linked 1 | -0.00889279 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00868656 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00862221 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00858994 |
| THY1 | Thy-1 cell surface antigen | -0.0085872 |
| PLPBP | pyridoxal phosphate binding protein | -0.00856135 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.00851083 |
| TLCD3A | TLC domain containing 3A | -0.00845353 |
| FABP7 | fatty acid binding protein 7, brain | -0.00843928 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00839088 |
| PITX1 | paired-like homeodomain 1 | -0.00835263 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00833843 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00824222 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00816497 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00806333 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00802504 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00801769 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00801554 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0080048 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00798125 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00797976 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0079621 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0079584 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00791975 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00789568 |
| S100A14 | S100 calcium binding protein A14 | -0.00787848 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00787368 |
| TOX | thymocyte selection-associated high mobility group box | -0.00785538 |
| MDFIC | MyoD family inhibitor domain containing | -0.00780641 |
| MGAM | maltase-glucoamylase | -0.00779393 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00776604 |
| FHL1 | four and a half LIM domains 1 | -0.00774505 |
| PGD | phosphogluconate dehydrogenase | -0.00771936 |
| KRT17 | keratin 17, type I | -0.00768968 |
| TCTN1 | tectonic family member 1 | -0.00765413 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00759081 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.0075685 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00755432 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00750805 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00746763 |
| SNX5 | sorting nexin 5 | -0.0074145 |
| ENO1 | enolase 1, (alpha) | -0.00741244 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00740016 |
| PRKCQ | protein kinase C, theta | -0.00733104 |
| H1-10 | H1.10 linker histone | -0.0072912 |
| FST | follistatin | -0.00728426 |
| RAB25 | RAB25, member RAS oncogene family | -0.00721525 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00713906 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00713209 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00709044 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00708319 |
| S100A10 | S100 calcium binding protein A10 | -0.00707646 |
| CTSH | cathepsin H | -0.00703349 |
| KRT8 | keratin 8, type II | -0.00701127 |
| EZR | ezrin | -0.00700716 |
| HK2 | hexokinase 2 | -0.00698278 |
| CHMP4A | charged multivesicular body protein 4A | -0.00695686 |
| SET | SET nuclear proto-oncogene | -0.00690336 |
| KRT19 | keratin 19, type I | -0.00687553 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00686436 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00683127 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00683001 |
| XPO7 | exportin 7 | -0.0067841 |
| DIAPH1 | diaphanous-related formin 1 | -0.00676677 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00674087 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00672967 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00669165 |
| ASS1 | argininosuccinate synthase 1 | -0.00664952 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00663042 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00656446 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00655474 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0065448 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00653289 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0064524 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00645207 |
| TMEM230 | transmembrane protein 230 | -0.00643917 |
| IL17RB | interleukin 17 receptor B | -0.00643525 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00643011 |
| HOPX | HOP homeobox | -0.00642883 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.00639485 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00639129 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | -0.00638915 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00635795 |
| WDR61 | WD repeat domain 61 | -0.00634725 |
| G0S2 | G0/G1 switch 2 | -0.00633862 |
| ATP5PD | ATP synthase peripheral stalk subunit d | -0.00633699 |
| PCTP | phosphatidylcholine transfer protein | -0.0063257 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00632192 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00631965 |
| DLD | dihydrolipoamide dehydrogenase | -0.00630282 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00629341 |
| NDRG1 | N-myc downstream regulated 1 | -0.00628282 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00627039 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00624948 |
| EPCAM | epithelial cell adhesion molecule | -0.00624009 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00623977 |
| C1QBP | complement component 1, q subcomponent binding protein | -0.00623678 |
| IL10RB | interleukin 10 receptor, beta | -0.0062303 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00622753 |
| STOML2 | stomatin (EPB72)-like 2 | -0.00622701 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.00620227 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00619211 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00618501 |
| MT2A | metallothionein 2A | -0.00618444 |
| PLIN2 | perilipin 2 | -0.00618059 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00617139 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00616235 |
| ADI1 | acireductone dioxygenase 1 | -0.00613385 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00613247 |
| COG7 | component of oligomeric golgi complex 7 | -0.00612186 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.00608696 |
| COQ9 | coenzyme Q9 | -0.00605717 |
| CCNA2 | cyclin A2 | -0.00604012 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00603094 |
| MAT2B | methionine adenosyltransferase II, beta | -0.00601232 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00600992 |
| RNASET2 | ribonuclease T2 | -0.00600691 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00600625 |
| IL1RN | interleukin 1 receptor antagonist | -0.005965 |
| MZB1 | marginal zone B and B1 cell-specific protein | -0.00595198 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00594506 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00592452 |
| TFF1 | trefoil factor 1 | -0.00589644 |
| TALDO1 | transaldolase 1 | -0.00589308 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00588391 |
| MRPL19 | mitochondrial ribosomal protein L19 | -0.00586428 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00585669 |
| LDB2 | LIM domain binding 2 | -0.00584195 |
| PPID | peptidylprolyl isomerase D | -0.0058333 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00583236 |
| TAGLN | transgelin | -0.00582381 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00581618 |
| PCLAF | PCNA clamp associated factor | -0.00579346 |
| PANK2 | pantothenate kinase 2 | -0.00579171 |
| PDZK1 | PDZ domain containing 1 | -0.00576827 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00573453 |
| NANOG | Nanog homeobox | -0.00571948 |
| RHOB | ras homolog family member B | -0.00571175 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00570388 |
| STOM | stomatin | -0.00569558 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00568827 |
| TRAM1 | translocation associated membrane protein 1 | -0.00567835 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00567628 |
| GUCY2C | guanylate cyclase 2C | -0.00566009 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 | -0.00564332 |
| KRT13 | keratin 13, type I | -0.00563346 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00560643 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00560307 |
| IL2RG | interleukin 2 receptor, gamma | -0.00559784 |
| KRT6A | keratin 6A, type II | -0.00559022 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00558726 |
| CAMP | cathelicidin antimicrobial peptide | -0.0055751 |
| PUDP | pseudouridine 5'-phosphatase | -0.00556963 |
| TPI1 | triosephosphate isomerase 1 | -0.00555384 |
| INAVA | innate immunity activator | -0.00555038 |
| MT1H | metallothionein 1H | -0.00553442 |
| ABHD4 | abhydrolase domain containing 4 | -0.00553376 |
| CNN2 | calponin 2 | -0.00553244 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00553211 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00553192 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00552833 |
| WASHC4 | WASH complex subunit 4 | -0.00552618 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00552242 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00550225 |
| KRT15 | keratin 15, type I | -0.00550175 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -0.00550021 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | -0.00548611 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00547444 |
| CPE | carboxypeptidase E | -0.00544433 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.005441 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00543784 |
| DAXX | death-domain associated protein | -0.00543402 |
| AAMDC | adipogenesis associated, Mth938 domain containing | -0.00543174 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 | -0.00542975 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00541646 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00541636 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00540885 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00536038 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00535275 |
| SMAD6 | SMAD family member 6 | -0.00534316 |
| CA9 | carbonic anhydrase IX | -0.00533027 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00532248 |
| EVI2A | ecotropic viral integration site 2A | -0.00531837 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00531741 |
| SMYD3 | SET and MYND domain containing 3 | -0.0053033 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | -0.00529425 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00529268 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00529053 |
| KRT6B | keratin 6B, type II | -0.00527538 |
| ERLIN2 | ER lipid raft associated 2 | -0.00526998 |
| PGK1 | phosphoglycerate kinase 1 | -0.00526139 |
| ANXA3 | annexin A3 | -0.00525797 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00525303 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -0.00524844 |
| CD200 | CD200 molecule | -0.00523244 |
| FERMT1 | fermitin family member 1 | -0.00522635 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00522267 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00522235 |
| METTL7A | methyltransferase like 7A | -0.00521708 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00520837 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00520576 |
| TSPAN13 | tetraspanin 13 | -0.00519469 |
| SALL1 | spalt-like transcription factor 1 | -0.00519424 |
| RBM47 | RNA binding motif protein 47 | -0.00518415 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00517044 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.005165 |
| TMEM45A | transmembrane protein 45A | -0.00515243 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | -0.00513201 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -0.00512159 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | -0.00511187 |
| FBXO2 | F-box protein 2 | -0.0050973 |
| MRS2 | MRS2 magnesium transporter | -0.00509614 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | -0.00508971 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00507823 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.00506514 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00505277 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00504995 |
