PCGF2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description polycomb group ring finger 2|The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7703)
External Link http://www.ncbi.nlm.nih.gov/gene/7703
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141 interacting proteins for PCGF2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABHD6 abhydrolase domain containing 6
ALYREF Aly/REF export factor
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
BCLAF1 BCL2-associated transcription factor 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
CBX2 chromobox homolog 2
CBX4 chromobox homolog 4
CBX6 chromobox homolog 6
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC158 coiled-coil domain containing 158
CCND2 cyclin D2
CD247 CD247 molecule
CENPF centromere protein F, 350/400kDa
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHD7 chromodomain helicase DNA binding protein 7
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DCAF7 DDB1 and CUL4 associated factor 7
DGKZ diacylglycerol kinase, zeta
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
E2F6 E2F transcription factor 6
EED embryonic ectoderm development
EGF epidermal growth factor
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
EP300 E1A binding protein p300
ERCC6 excision repair cross-complementation group 6
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
FBL fibrillarin
FER fer (fps/fes related) tyrosine kinase
GJB5 gap junction protein, beta 5, 31.1kDa
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GTPBP4 GTP binding protein 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1A histone cluster 1, H1a
HIST1H2AB histone cluster 1, H2ab
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H4F histone cluster 1, H4f
HLF hepatic leukemia factor
HMGN5 high mobility group nucleosome binding domain 5
HNF4A hepatocyte nuclear factor 4, alpha
HOXC9 homeobox C9
HSF1 heat shock transcription factor 1
HSF2 heat shock transcription factor 2
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ILF2 interleukin enhancer binding factor 2
ILF3 interleukin enhancer binding factor 3, 90kDa
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0020 KIAA0020
KIF20B kinesin family member 20B
KRI1 KRI1 homolog (S. cerevisiae)
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LIG3 ligase III, DNA, ATP-dependent
LMNA lamin A/C
LMNB1 lamin B1
LTV1 LTV1 ribosome biogenesis factor
MDM1 Mdm1 nuclear protein homolog (mouse)
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKI67 marker of proliferation Ki-67
MOV10 Mov10 RISC complex RNA helicase
NBN nibrin
NFIL3 nuclear factor, interleukin 3 regulated
NOP2 NOP2 nucleolar protein
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUCLEOLIN nucleolin multifunctional protein
PCBP1 poly(rC) binding protein 1
PCGF1 polycomb group ring finger 1
PCGF3 polycomb group ring finger 3
PCGF5 polycomb group ring finger 5
PCGF6 polycomb group ring finger 6
PDCD11 programmed cell death 11
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PML promyelocytic leukemia
PPAN peter pan homolog (Drosophila)
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
RAD17 RAD17 homolog (S. pombe)
RANGAP1 Ran GTPase activating protein 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RING1 ring finger protein 1
RNF17 ring finger protein 17
RNF2 ring finger protein 2
RUVBL2 RuvB-like AAA ATPase 2
RYBP RING1 and YY1 binding protein
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML1 sex comb on midleg-like 1 (Drosophila)
SETD2 SET domain containing 2
SFN stratifin
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SMC3 structural maintenance of chromosomes 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPAG9 sperm associated antigen 9
SPDEF SAM pointed domain containing ETS transcription factor
SPECC1 sperm antigen with calponin homology and coiled-coil domains 1
SRBD1 S1 RNA binding domain 1
STAMBPL1 STAM binding protein-like 1
STAU1 staufen double-stranded RNA binding protein 1
TBP TATA box binding protein
TMPO thymopoietin
TPR translocated promoter region, nuclear basket protein
TRIM28 tripartite motif containing 28
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2I ubiquitin-conjugating enzyme E2I
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2T ubiquitin-conjugating enzyme E2T
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE4A ubiquitination factor E4A
UBR1 ubiquitin protein ligase E3 component n-recognin 1
USP11 ubiquitin specific peptidase 11
USP20 ubiquitin specific peptidase 20
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDHD1 WD repeat and HMG-box DNA binding protein 1
YAF2 YY1 associated factor 2
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YTHDC2 YTH domain containing 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZCCHC3 zinc finger, CCHC domain containing 3
ZFR zinc finger RNA binding protein
ZNF546 zinc finger protein 546
ZNF717 zinc finger protein 717