PCI-15A Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from -666 (Catalogue of Somatic Mutations In Cancer)
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Genes

344 genes mutated in the PCI-15A cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACADVL acyl-CoA dehydrogenase, very long chain
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
ADAMTSL4 ADAMTS-like 4
ADCY2 adenylate cyclase 2 (brain)
ADGRA1 adhesion G protein-coupled receptor A1
ADGRG6 adhesion G protein-coupled receptor G6
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6
AHCTF1 AT hook containing transcription factor 1
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AJUBA ajuba LIM protein
AK5 adenylate kinase 5
AKAP8 A kinase (PRKA) anchor protein 8
ALPK3 alpha-kinase 3
AMBRA1 autophagy/beclin-1 regulator 1
AMY2A amylase, alpha 2A (pancreatic)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD12 ankyrin repeat domain 12
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
APTX aprataxin
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP5 Rho GTPase activating protein 5
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
AS3MT arsenite methyltransferase
ASB16 ankyrin repeat and SOCS box containing 16
ASB9 ankyrin repeat and SOCS box containing 9
ASPH aspartate beta-hydroxylase
ATG9A autophagy related 9A
ATP13A2 ATPase type 13A2
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATXN3 ataxin 3
BANK1 B-cell scaffold protein with ankyrin repeats 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BLM Bloom syndrome, RecQ helicase-like
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BPTF bromodomain PHD finger transcription factor
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CACHD1 cache domain containing 1
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAPN13 calpain 13
CASC5 cancer susceptibility candidate 5
CATSPER1 cation channel, sperm associated 1
CBY1 chibby homolog 1 (Drosophila)
CCDC54 coiled-coil domain containing 54
CCDC60 coiled-coil domain containing 60
CCDC91 coiled-coil domain containing 91
CCNA1 cyclin A1
CD109 CD109 molecule
CD22 CD22 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CENPJ centromere protein J
CH25H cholesterol 25-hydroxylase
CHD2 chromodomain helicase DNA binding protein 2
CHRDL2 chordin-like 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CLCA4 chloride channel accessory 4
CLCN2 chloride channel, voltage-sensitive 2
COL14A1 collagen, type XIV, alpha 1
COL20A1 collagen, type XX, alpha 1
COMP cartilage oligomeric matrix protein
CPNE5 copine V
CROT carnitine O-octanoyltransferase
CST3 cystatin C
DEDD2 death effector domain containing 2
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIDO1 death inducer-obliterator 1
DNA2 DNA replication helicase/nuclease 2
DNAH17 dynein, axonemal, heavy chain 17
DOCK1 dedicator of cytokinesis 1
DOCK9 dedicator of cytokinesis 9
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPY19L1 dpy-19-like 1 (C. elegans)
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DUOX1 dual oxidase 1
DUSP8 dual specificity phosphatase 8
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDAR ectodysplasin A receptor
ELN elastin
ENGASE endo-beta-N-acetylglucosaminidase
ERICH1 glutamate-rich 1
ERLIN1 ER lipid raft associated 1
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ESPN espin
EVX1 even-skipped homeobox 1
EXOSC10 exosome component 10
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM104B family with sequence similarity 104, member B
FAM160B2 family with sequence similarity 160, member B2
FAM47A family with sequence similarity 47, member A
FAM86C1 family with sequence similarity 86, member C1
FANCM Fanconi anemia, complementation group M
FASTKD5 FAST kinase domains 5
FCRL4 Fc receptor-like 4
FER1L6 fer-1-like family member 6
FGF10 fibroblast growth factor 10
FIGN fidgetin
FKBP15 FK506 binding protein 15, 133kDa
FKBP6 FK506 binding protein 6, 36kDa
FOLH1B folate hydrolase 1B
FSCN3 fascin actin-bundling protein 3, testicular
GAA glucosidase, alpha; acid
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALC galactosylceramidase
GANAB glucosidase, alpha; neutral AB
GCKR glucokinase (hexokinase 4) regulator
GFRA2 GDNF family receptor alpha 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIGYF2 GRB10 interacting GYF protein 2
GPR158 G protein-coupled receptor 158
GSTZ1 glutathione S-transferase zeta 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HELB helicase (DNA) B
HIAT1 hippocampus abundant transcript 1
HIST1H2AI histone cluster 1, H2ai
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTRA3 HtrA serine peptidase 3
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
IFNA7 interferon, alpha 7
IGSF21 immunoglobin superfamily, member 21
IGSF22 immunoglobulin superfamily, member 22
IL1R2 interleukin 1 receptor, type II
IL27RA interleukin 27 receptor, alpha
ING2 inhibitor of growth family, member 2
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPO5 importin 5
KANK2 KN motif and ankyrin repeat domains 2
KATNAL2 katanin p60 subunit A-like 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KIAA1210 KIAA1210
KIAA1324L KIAA1324-like
KIF14 kinesin family member 14
KIF1B kinesin family member 1B
KIF23 kinesin family member 23
KIF24 kinesin family member 24
KIF4B kinesin family member 4B
KLC1 kinesin light chain 1
KNG1 kininogen 1
KRT6A keratin 6A, type II
KRT8 keratin 8, type II
KRTAP10-9 keratin associated protein 10-9
LAMA1 laminin, alpha 1
LAMA2 laminin, alpha 2
LAT linker for activation of T cells
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC541473 FK506 binding protein 6, 36kDa pseudogene
LPA lipoprotein, Lp(a)
LRP1B low density lipoprotein receptor-related protein 1B
LRRC43 leucine rich repeat containing 43
LRRK1 leucine-rich repeat kinase 1
LTBP2 latent transforming growth factor beta binding protein 2
MACROD2 MACRO domain containing 2
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAGED2 melanoma antigen family D2
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAP3K15 mitogen-activated protein kinase kinase kinase 15
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK10 mitogen-activated protein kinase 10
MARCKSL1 MARCKS-like 1
MED12L mediator complex subunit 12-like
MGAT4C MGAT4 family, member C
MIDN midnolin
MKI67 marker of proliferation Ki-67
MOXD1 monooxygenase, DBH-like 1
MPL MPL proto-oncogene, thrombopoietin receptor
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MROH2A maestro heat-like repeat family member 2A
MTERF4 mitochondrial transcription termination factor 4
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC16 mucin 16, cell surface associated
MXRA5 matrix-remodelling associated 5
MYH10 myosin, heavy chain 10, non-muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYO3A myosin IIIA
NCOR1 nuclear receptor corepressor 1
NEB nebulin
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NLRP3 NLR family, pyrin domain containing 3
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOTCH1 notch 1
NOX3 NADPH oxidase 3
NPPA natriuretic peptide A
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1
NWD1 NACHT and WD repeat domain containing 1
OMD osteomodulin
OR13C2 olfactory receptor, family 13, subfamily C, member 2
OR2A4 olfactory receptor, family 2, subfamily A, member 4
OR2H1 olfactory receptor, family 2, subfamily H, member 1
OR4A13P olfactory receptor, family 4, subfamily A, member 13 pseudogene
OR5R1 olfactory receptor, family 5, subfamily R, member 1 (gene/pseudogene)
ORC2 origin recognition complex, subunit 2
OTOA otoancorin
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PARD6G par-6 family cell polarity regulator gamma
PARVB parvin, beta
PC pyruvate carboxylase
PCDH12 protocadherin 12
PCDHA6 protocadherin alpha 6
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDHX pyruvate dehydrogenase complex, component X
PELO pelota homolog (Drosophila)
PHACTR4 phosphatase and actin regulator 4
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIWIL4 piwi-like RNA-mediated gene silencing 4
PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
PKN3 protein kinase N3
PLA2G3 phospholipase A2, group III
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLCD3 phospholipase C, delta 3
PLXNA1 plexin A1
PNMAL2 paraneoplastic Ma antigen family-like 2
POMT2 protein-O-mannosyltransferase 2
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRAMEF11 PRAME family member 11
PRDM9 PR domain containing 9
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1
PRSS48 protease, serine, 48
PTCD1 pentatricopeptide repeat domain 1
PTCH2 patched 2
PTGFRN prostaglandin F2 receptor inhibitor
PTOV1 prostate tumor overexpressed 1
RAI14 retinoic acid induced 14
RBM12B RNA binding motif protein 12B
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RHEBL1 Ras homolog enriched in brain like 1
RHOJ ras homolog family member J
RNF40 ring finger protein 40, E3 ubiquitin protein ligase
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RP1L1 retinitis pigmentosa 1-like 1
RPL29P12 ribosomal protein L29 pseudogene 12
RPS12P22 ribosomal protein S12 pseudogene 22
SAMD4A sterile alpha motif domain containing 4A
SAMD9 sterile alpha motif domain containing 9
SCARB1 scavenger receptor class B, member 1
SDC2 syndecan 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEPT4 septin 4
SERINC3 serine incorporator 3
SETMAR SET domain and mariner transposase fusion gene
SGSM2 small G protein signaling modulator 2
SHISA7 shisa family member 7
SHKBP1 SH3KBP1 binding protein 1
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC22A25 solute carrier family 22, member 25
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A34 solute carrier family 25, member 34
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3
SLC35F1 solute carrier family 35, member F1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
SLCO5A1 solute carrier organic anion transporter family, member 5A1
SLITRK5 SLIT and NTRK-like family, member 5
SMC4 structural maintenance of chromosomes 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMYD5 SMYD family member 5
SNED1 sushi, nidogen and EGF-like domains 1
SPHKAP SPHK1 interactor, AKAP domain containing
SPRTN SprT-like N-terminal domain
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSC5D scavenger receptor cysteine rich family, 5 domains
SSTR2 somatostatin receptor 2
STAU2 staufen double-stranded RNA binding protein 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK32B serine/threonine kinase 32B
STRN3 striatin, calmodulin binding protein 3
SUSD5 sushi domain containing 5
TACC2 transforming, acidic coiled-coil containing protein 2
TBR1 T-box, brain, 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TCP10L2 t-complex 10-like 2
TDG thymine-DNA glycosylase
TGFB2 transforming growth factor, beta 2
THAP9 THAP domain containing 9
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TMC1 transmembrane channel-like 1
TMCO4 transmembrane and coiled-coil domains 4
TMEM130 transmembrane protein 130
TMEM132C transmembrane protein 132C
TMPO thymopoietin
TNNI3K TNNI3 interacting kinase
TNNT3 troponin T type 3 (skeletal, fast)
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM2 tripartite motif containing 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSGA10IP testis specific, 10 interacting protein
TSHZ2 teashirt zinc finger homeobox 2
TSHZ3 teashirt zinc finger homeobox 3
TTC6 tetratricopeptide repeat domain 6
TTC8 tetratricopeptide repeat domain 8
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB7P tubulin, beta 7, pseudogene
TXLNGY taxilin gamma pseudogene, Y-linked
UBAC1 UBA domain containing 1
UBXN11 UBX domain protein 11
USF2 upstream transcription factor 2, c-fos interacting
USP32 ubiquitin specific peptidase 32
USP9Y ubiquitin specific peptidase 9, Y-linked
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VCAN versican
VWA1 von Willebrand factor A domain containing 1
VWA9 von Willebrand factor A domain containing 9
WDHD1 WD repeat and HMG-box DNA binding protein 1
WDR66 WD repeat domain 66
XPO5 exportin 5
ZFHX3 zinc finger homeobox 3
ZIC1 Zic family member 1
ZNF207 zinc finger protein 207
ZNF26 zinc finger protein 26
ZNF335 zinc finger protein 335
ZNF569 zinc finger protein 569
ZNF611 zinc finger protein 611
ZNF626 zinc finger protein 626
ZNF655 zinc finger protein 655
ZNF683 zinc finger protein 683
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1