PCI-30 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description cell line derived from -666 (Catalogue of Somatic Mutations In Cancer)
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Genes

239 genes with high or low copy number in PCI-30 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
AFF3 AF4/FMR2 family, member 3 4.51153
TMEM127 transmembrane protein 127 4.51153
CIAO1 cytosolic iron-sulfur assembly component 1 4.51153
DUSP2 dual specificity phosphatase 2 4.51153
ADRA2B adrenoceptor alpha 2B 4.51153
PROM2 prominin 2 4.51153
ASTL astacin-like metallo-endopeptidase (M12 family) 4.51153
STARD7 StAR-related lipid transfer (START) domain containing 7 4.51153
TMEM131 transmembrane protein 131 3.12177
VWA3B von Willebrand factor A domain containing 3B 3.12177
TEKT4 tektin 4 3.12177
LOC442028 uncharacterized LOC442028 3.12177
ANKRD36 ankyrin repeat domain 36 3.12177
MAL mal, T-cell differentiation protein 3.12177
C2ORF15 chromosome 2 open reading frame 15 3.12177
ANKRD39 ankyrin repeat domain 39 3.12177
FAM178B family with sequence similarity 178, member B 3.12177
FER1L5 fer-1-like family member 5 3.12177
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) 3.12177
MIR3127 microRNA 3127 3.12177
LIPT1 lipoyltransferase 1 3.12177
MITD1 MIT, microtubule interacting and transport, domain containing 1 3.12177
ZNF2 zinc finger protein 2 3.12177
COA5 cytochrome c oxidase assembly factor 5 3.12177
KIAA1211L KIAA1211-like 3.12177
LYG2 lysozyme G-like 2 3.12177
LYG1 lysozyme G-like 1 3.12177
LMAN2L lectin, mannose-binding 2-like 3.12177
TSGA10 testis specific, 10 3.12177
TXNDC9 thioredoxin domain containing 9 3.12177
ANKRD23 ankyrin repeat domain 23 3.12177
LOC100506123 uncharacterized LOC100506123 3.12177
FAHD2B fumarylacetoacetate hydrolase domain containing 2B 3.12177
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 3.12177
NCAPH non-SMC condensin I complex, subunit H 3.12177
NEURL3 neuralized E3 ubiquitin protein ligase 3 3.12177
KANSL3 KAT8 regulatory NSL complex subunit 3 3.12177
CNGA3 cyclic nucleotide gated channel alpha 3 3.12177
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 3.12177
MRPS5 mitochondrial ribosomal protein S5 3.12177
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 3.12177
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 3.12177
COX5B cytochrome c oxidase subunit Vb 3.12177
ARID5A AT rich interactive domain 5A (MRF1-like) 3.12177
ZNF514 zinc finger protein 514 3.12177
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 3.12177
EIF5B eukaryotic translation initiation factor 5B 3.12177
ANKRD36B ankyrin repeat domain 36B 3.12177
MRPL30 mitochondrial ribosomal protein L30 3.12177
REV1 REV1, polymerase (DNA directed) 3.12177
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 3.12177
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 3.12177
UNC50 unc-50 homolog (C. elegans) 3.12177
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 3.12177
SEPT7P9 septin 7 pseudogene 9 2.93899
FAM95A family with sequence similarity 95, member A 2.93899
HSD17B7P2 hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2 2.93899
ZNF37A zinc finger protein 37A 2.93899
TRIM43 tripartite motif containing 43 2.93899
ANKRD20A8P ankyrin repeat domain 20 family, member A8, pseudogene 2.93899
FAHD2A fumarylacetoacetate hydrolase domain containing 2A 2.93899
ZNF33A zinc finger protein 33A 2.93899
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.93899
ZNF25 zinc finger protein 25 2.93899
KCNIP3 Kv channel interacting protein 3, calsenilin 2.93899
LOC100129055 cyclin Y-like 1 pseudogene 2.93899
FAHD2CP fumarylacetoacetate hydrolase domain containing 2C, pseudogene 2.93899
ANKRD36C ankyrin repeat domain 36C 2.93899
TRIM43B tripartite motif containing 43B 2.93899
FZD8 frizzled class receptor 8 2.64759
CREM cAMP responsive element modulator 2.64759
ANKRD30A ankyrin repeat domain 30A 2.64759
GJD4 gap junction protein, delta 4, 40.1kDa 2.64759
ZNF248 zinc finger protein 248 2.64759
GRB2 growth factor receptor-bound protein 2 2.64759
MTRNR2L7 MT-RNR2-like 7 2.64759
ZNF33BP1 zinc finger protein 33B pseudogene 1 2.64759
CUL2 cullin 2 2.64759
MIR3678 microRNA 3678 2.64759
MIF4GD MIF4G domain containing 2.59653
CYGB cytoglobin 2.59653
ITGB4 integrin, beta 4 2.59653
ARMC7 armadillo repeat containing 7 2.59653
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.59653
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.59653
AANAT aralkylamine N-acetyltransferase 2.59653
EXOC7 exocyst complex component 7 2.59653
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.59653
SRP68 signal recognition particle 68kDa 2.59653
SUMO2 small ubiquitin-like modifier 2 2.59653
MIR4738 microRNA 4738 2.59653
ZACN zinc activated ligand-gated ion channel 2.59653
FOXJ1 forkhead box J1 2.59653
QRICH2 glutamine rich 2 2.59653
NT5C 5', 3'-nucleotidase, cytosolic 2.59653
GALR2 galanin receptor 2 2.59653
CASKIN2 CASK interacting protein 2 2.59653
RNF157 ring finger protein 157 2.59653
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 2.59653
RNF157-AS1 RNF157 antisense RNA 1 2.59653
SPHK1 sphingosine kinase 1 2.59653
UBE2O ubiquitin-conjugating enzyme E2O 2.59653
TSEN54 TSEN54 tRNA splicing endonuclease subunit 2.59653
H3F3B H3 histone, family 3B (H3.3B) 2.59653
CCNY cyclin Y 2.59653
SNORD1A small nucleolar RNA, C/D box 1A 2.59653
SNORD1B small nucleolar RNA, C/D box 1B 2.59653
RHBDF2 rhomboid 5 homolog 2 (Drosophila) 2.59653
SNORD1C small nucleolar RNA, C/D box 1C 2.59653
SNHG16 small nucleolar RNA host gene 16 2.59653
JMJD6 jumonji domain containing 6 2.59653
NUP85 nucleoporin 85kDa 2.59653
GALK1 galactokinase 1 2.59653
MRPS7 mitochondrial ribosomal protein S7 2.59653
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3 2.59653
LOC100287042 uncharacterized LOC100287042 2.59653
MXRA7 matrix-remodelling associated 7 2.59653
UBALD2 UBA-like domain containing 2 2.59653
HN1 hematological and neurological expressed 1 2.59653
PRCD progressive rod-cone degeneration 2.59653
LINC00838 long intergenic non-protein coding RNA 838 2.49065
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.49065
TRIM47 tripartite motif containing 47 2.49065
RECQL5 RecQ protein-like 5 2.49065
ACOX1 acyl-CoA oxidase 1, palmitoyl 2.49065
SMIM6 small integral membrane protein 6 2.49065
SMIM5 small integral membrane protein 5 2.49065
SAP30BP SAP30 binding protein 2.49065
LLGL2 lethal giant larvae homolog 2 (Drosophila) 2.49065
UNK unkempt family zinc finger 2.49065
UNC13D unc-13 homolog D (C. elegans) 2.49065
COLEC12 collectin sub-family member 12 2.49065
MYO15B myosin XVB 2.49065
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 2.49065
THOC1 THO complex 1 2.49065
CDK3 cyclin-dependent kinase 3 2.49065
MRPL38 mitochondrial ribosomal protein L38 2.49065
WBP2 WW domain binding protein 2 2.49065
EVPL envoplakin 2.49065
LOC441155 zinc finger CCCH-type domain-containing-like 2.49065
TRIM65 tripartite motif containing 65 2.49065
FBF1 Fas (TNFRSF6) binding factor 1 2.49065
CETN1 centrin, EF-hand protein, 1 2.44392
LOC100131257 zinc finger protein 655 pseudogene 2.44392
YES1 YES proto-oncogene 1, Src family tyrosine kinase 2.41451
LXN latexin 2.41451
GFM1 G elongation factor, mitochondrial 1 2.41451
CLUL1 clusterin-like 1 (retinal) 2.41451
ENOSF1 enolase superfamily member 1 2.41451
MLF1 myeloid leukemia factor 1 2.41451
TYMS thymidylate synthetase 2.41451
SHOX2 short stature homeobox 2 2.39327
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 2.39327
RSRC1 arginine/serine-rich coiled-coil 1 2.39327
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.39327
FOLR3 folate receptor 3 (gamma) 2.36889
FOLR2 folate receptor 2 (fetal) 2.36889
FOLR1 folate receptor 1 (adult) 2.36889
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 2.35236
ANAPC15 anaphase promoting complex subunit 15 2.35236
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 2.35236
RPA3 replication protein A3, 14kDa 2.35236
MIR3165 microRNA 3165 2.3178
RNF121 ring finger protein 121 2.3178
COL28A1 collagen, type XXVIII, alpha 1 2.3178
LOC100129216 beta-defensin 131-like 2.3178
GLCCI1 glucocorticoid induced 1 2.3178
LOC100133315 transient receptor potential cation channel, subfamily C, member 2-like 2.3178
IL18BP interleukin 18 binding protein 2.3178
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing 2.3178
NUMA1 nuclear mitotic apparatus protein 1 2.3178
ICA1 islet cell autoantigen 1, 69kDa 2.30944
NXPH1 neurexophilin 1 2.30944
ECT2 epithelial cell transforming 2 2.30944
SPATA16 spermatogenesis associated 16 2.283
NLGN1 neuroligin 1 2.26395
SEPT14 septin 14 2.2355
HPVC1 human papillomavirus (type 18) E5 central sequence-like 1 2.22793
VSTM2A V-set and transmembrane domain containing 2A 2.22633
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 2.22123
SEC61G Sec61 gamma subunit 2.21727
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) 2.21727
EGFR-AS1 EGFR antisense RNA 1 2.21096
EGFR epidermal growth factor receptor 2.20309
MIR548K microRNA 548k 2.16564
FADD Fas (TNFRSF6)-associated via death domain 2.16564
MYEOV myeloma overexpressed 2.16459
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 2.16459
CTTN cortactin 2.16307
FGF3 fibroblast growth factor 3 2.16307
ANO1 anoctamin 1, calcium activated chloride channel 2.16307
FGF4 fibroblast growth factor 4 2.16176
CCND1 cyclin D1 2.1605
FGF19 fibroblast growth factor 19 2.1605
ORAOV1 oral cancer overexpressed 1 2.16017
LOC646813 DEAH (Asp-Glu-Ala-His) box helicase 9 pseudogene 2.12931
LOC441601 septin 7 pseudogene 2.12506
TRIM49B tripartite motif containing 49B 2.12225
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 2.12225
TRIM64C tripartite motif containing 64C 2.12225
OR4C12 olfactory receptor, family 4, subfamily C, member 12 2.10992
OR4C13 olfactory receptor, family 4, subfamily C, member 13 2.10992
LOC440040 glutamate receptor, metabotropic 5 pseudogene 2.10992
KIAA0195 KIAA0195 2.10038
SLC25A51P1 solute carrier family 25, member 51 pseudogene 1 2.10038
PARD3 par-3 family cell polarity regulator 2.09294
DUX4 double homeobox 4 2.09117
OSTN osteocrin 2.08781
EYS eyes shut homolog (Drosophila) 2.08391
GMNC geminin coiled-coil domain containing 2.08391
SNAR-I small ILF3/NF90-associated RNA I 2.08391
IL1RAP interleukin 1 receptor accessory protein 2.08066
CLDN16 claudin 16 2.08066
MIR944 microRNA 944 2.08066
TPRG1-AS2 TPRG1 antisense RNA 2 2.08066
CLDN1 claudin 1 2.08066
P3H2 prolyl 3-hydroxylase 2 2.08066
TMEM207 transmembrane protein 207 2.08066
TP63 tumor protein p63 2.07822
TPRG1 tumor protein p63 regulated 1 2.07558
NAALADL2-AS3 NAALADL2 antisense RNA 3 2.0703
MIR4789 microRNA 4789 2.06989
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 2.06592
SI sucrase-isomaltase (alpha-glucosidase) 2.06505
BCHE butyrylcholinesterase 2.06473
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 2.06473
SLITRK3 SLIT and NTRK-like family, member 3 2.06473
ZBBX zinc finger, B-box domain containing 2.06316
GOLIM4 golgi integral membrane protein 4 2.06316
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.06316
PDCD10 programmed cell death 10 2.06316
WDR49 WD repeat domain 49 2.06316
MIR551B microRNA 551b 2.0622
EGFEM1P EGF-like and EMI domain containing 1, pseudogene 2.06105
MECOM MDS1 and EVI1 complex locus 2.06061
SHANK2-AS1 SHANK2 antisense RNA 1 2.05422
SHANK2 SH3 and multiple ankyrin repeat domains 2 2.04969
CDH18 cadherin 18, type 2 2.0489

low copy number

Symbol Name Standardized Value
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -3.04299