PCI-38 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from -666 (Catalogue of Somatic Mutations In Cancer)
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Genes

413 genes mutated in the PCI-38 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
A2M alpha-2-macroglobulin
AARS alanyl-tRNA synthetase
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ABHD16A abhydrolase domain containing 16A
ACBD4 acyl-CoA binding domain containing 4
ACOT11 acyl-CoA thioesterase 11
ACOXL acyl-CoA oxidase-like
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM33 ADAM metallopeptidase domain 33
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADCY9 adenylate cyclase 9
ADGRB2 adhesion G protein-coupled receptor B2
ADH6 alcohol dehydrogenase 6 (class V)
AFF2 AF4/FMR2 family, member 2
AGMO alkylglycerol monooxygenase
AHNAK2 AHNAK nucleoprotein 2
AKAP3 A kinase (PRKA) anchor protein 3
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOXE3 arachidonate lipoxygenase 3
AMOTL2 angiomotin like 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKAR ankyrin and armadillo repeat containing
ANKRD30B ankyrin repeat domain 30B
ANKRD55 ankyrin repeat domain 55
ANO1 anoctamin 1, calcium activated chloride channel
ANO6 anoctamin 6
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APC2 adenomatosis polyposis coli 2
AQP7 aquaporin 7
ARHGAP20 Rho GTPase activating protein 20
ARHGAP32 Rho GTPase activating protein 32
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33
ATP13A1 ATPase type 13A1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATR ATR serine/threonine kinase
ATXN3 ataxin 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
BAG6 BCL2-associated athanogene 6
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBS12 Bardet-Biedl syndrome 12
BCL7C B-cell CLL/lymphoma 7C
BIRC6 baculoviral IAP repeat containing 6
BROX BRO1 domain and CAAX motif containing
BTNL2 butyrophilin-like 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALB1 calbindin 1, 28kDa
CALCA calcitonin-related polypeptide alpha
CAT catalase
CATSPERB catsper channel auxiliary subunit beta
CC2D1A coiled-coil and C2 domain containing 1A
CC2D1B coiled-coil and C2 domain containing 1B
CCDC108 coiled-coil domain containing 108
CCDC136 coiled-coil domain containing 136
CCNG2 cyclin G2
CDH18 cadherin 18, type 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP135 centrosomal protein 135kDa
CEP164 centrosomal protein 164kDa
CGB7 chorionic gonadotropin, beta polypeptide 7
CHKA choline kinase alpha
CLCN2 chloride channel, voltage-sensitive 2
CMYA5 cardiomyopathy associated 5
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNOT1 CCR4-NOT transcription complex, subunit 1
COL15A1 collagen, type XV, alpha 1
COL23A1 collagen, type XXIII, alpha 1
COL6A3 collagen, type VI, alpha 3
COL6A6 collagen, type VI, alpha 6
COL7A1 collagen, type VII, alpha 1
COMMD4 COMM domain containing 4
CPM carboxypeptidase M
CPNE6 copine VI (neuronal)
CSAG4 CSAG family, member 4 (pseudogene)
CSHL1 chorionic somatomammotropin hormone-like 1
CSMD3 CUB and Sushi multiple domains 3
CSPG4 chondroitin sulfate proteoglycan 4
CTDNEP1 CTD nuclear envelope phosphatase 1
CYB5R3 cytochrome b5 reductase 3
CYGB cytoglobin
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYSLTR1 cysteinyl leukotriene receptor 1
DAPK2 death-associated protein kinase 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DGKI diacylglycerol kinase, iota
DGKZ diacylglycerol kinase, zeta
DICER1 dicer 1, ribonuclease type III
DLG2 discs, large homolog 2 (Drosophila)
DNAH12 dynein, axonemal, heavy chain 12
DNAH3 dynein, axonemal, heavy chain 3
DNAH6 dynein, axonemal, heavy chain 6
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOCK10 dedicator of cytokinesis 10
DOK6 docking protein 6
DOLPP1 dolichyldiphosphatase 1
DPYS dihydropyrimidinase
DTWD2 DTW domain containing 2
DUSP4 dual specificity phosphatase 4
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA6 EPH receptor A6
EPHA8 EPH receptor A8
EPS8L3 EPS8-like 3
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ERRFI1 ERBB receptor feedback inhibitor 1
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1
ESRP2 epithelial splicing regulatory protein 2
ESYT3 extended synaptotagmin-like protein 3
EVC Ellis van Creveld protein
EVI5 ecotropic viral integration site 5
FAM134B family with sequence similarity 134, member B
FASTKD3 FAST kinase domains 3
FBLN1 fibulin 1
FCHO1 FCH domain only 1
FKBP5 FK506 binding protein 5
FKBP8 FK506 binding protein 8, 38kDa
FLG filaggrin
FLOT1 flotillin 1
FN1 fibronectin 1
FNDC3B fibronectin type III domain containing 3B
FOXP2 forkhead box P2
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
FRMD3 FERM domain containing 3
FSD1L fibronectin type III and SPRY domain containing 1-like
FUBP1 far upstream element (FUSE) binding protein 1
FUCA2 fucosidase, alpha-L- 2, plasma
FUK fucokinase
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD4 frizzled class receptor 4
GALNS galactosamine (N-acetyl)-6-sulfatase
GATA6 GATA binding protein 6
GBP1 guanylate binding protein 1, interferon-inducible
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GH1 growth hormone 1
GIGYF1 GRB10 interacting GYF protein 1
GJC1 gap junction protein, gamma 1, 45kDa
GLI2 GLI family zinc finger 2
GLI4 GLI family zinc finger 4
GLUD2 glutamate dehydrogenase 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPATCH2L G patch domain containing 2-like
GPX3 glutathione peroxidase 3
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GSG2 germ cell associated 2 (haspin)
HAUS8 HAUS augmin-like complex, subunit 8
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDAC1 histone deacetylase 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIP1 huntingtin interacting protein 1
HLA-C major histocompatibility complex, class I, C
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
HNF4A hepatocyte nuclear factor 4, alpha
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IDO1 indoleamine 2,3-dioxygenase 1
IGF2R insulin-like growth factor 2 receptor
IMPG2 interphotoreceptor matrix proteoglycan 2
INO80C INO80 complex subunit C
INO80E INO80 complex subunit E
IQCG IQ motif containing G
IRAK2 interleukin-1 receptor-associated kinase 2
IRF2BPL interferon regulatory factor 2 binding protein-like
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JAG2 jagged 2
KANK4 KN motif and ankyrin repeat domains 4
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KDM3A lysine (K)-specific demethylase 3A
KERA keratocan
KIAA0232 KIAA0232
KIF18A kinesin family member 18A
KIF5C kinesin family member 5C
KITLG KIT ligand
KLC4 kinesin light chain 4
KLHL29 kelch-like family member 29
KMT2C lysine (K)-specific methyltransferase 2C
KRI1 KRI1 homolog (S. cerevisiae)
KRT79 keratin 79, type II
KTN1 kinectin 1 (kinesin receptor)
LAMB4 laminin, beta 4
LATS1 large tumor suppressor kinase 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINS lines homolog (Drosophila)
LIPH lipase, member H
LMAN1L lectin, mannose-binding, 1 like
LONP1 lon peptidase 1, mitochondrial
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTN1 listerin E3 ubiquitin protein ligase 1
LYST lysosomal trafficking regulator
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAN2A1 mannosidase, alpha, class 2A, member 1
MBLAC2 metallo-beta-lactamase domain containing 2
MED23 mediator complex subunit 23
MED27 mediator complex subunit 27
MITF microphthalmia-associated transcription factor
MLN motilin
MLXIPL MLX interacting protein-like
MRPL44 mitochondrial ribosomal protein L44
MSH2 mutS homolog 2
MSR1 macrophage scavenger receptor 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC12 mucin 12, cell surface associated
MUC16 mucin 16, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
MYO1A myosin IA
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NAIP NLR family, apoptosis inhibitory protein
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NELL2 NEL-like 2 (chicken)
NFE2L3 nuclear factor, erythroid 2-like 3
NPHP3 nephronophthisis 3 (adolescent)
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRCAM neuronal cell adhesion molecule
NRG1 neuregulin 1
NVL nuclear VCP-like
OPTC opticin
OR10H4 olfactory receptor, family 10, subfamily H, member 4
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1
OR1S2 olfactory receptor, family 1, subfamily S, member 2
OR2T2 olfactory receptor, family 2, subfamily T, member 2
OR2V2 olfactory receptor, family 2, subfamily V, member 2
OR4S1 olfactory receptor, family 4, subfamily S, member 1
OR52H1 olfactory receptor, family 52, subfamily H, member 1
OTOF otoferlin
OTUD4 OTU deubiquitinase 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGA5 protocadherin gamma subfamily A, 5
PDE8A phosphodiesterase 8A
PDHX pyruvate dehydrogenase complex, component X
PGBD4 piggyBac transposable element derived 4
PHF20L1 PHD finger protein 20-like 1
PHOX2B paired-like homeobox 2b
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITPNM3 PITPNM family member 3
PLA2G4E phospholipase A2, group IVE
PLCL1 phospholipase C-like 1
PLEC plectin
PLEK pleckstrin
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PLG plasminogen
PLSCR5 phospholipid scramblase family, member 5
PLXNB2 plexin B2
POTEF POTE ankyrin domain family, member F
POTEH POTE ankyrin domain family, member H
PPP1R26 protein phosphatase 1, regulatory subunit 26
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDM1 PR domain containing 1, with ZNF domain
PRDM15 PR domain containing 15
PRICKLE4 prickle homolog 4 (Drosophila)
PRMT7 protein arginine methyltransferase 7
PRR22 proline rich 22
PRSS1 protease, serine, 1 (trypsin 1)
PRUNE2 prune homolog 2 (Drosophila)
PSAP prosaposin
PTK2 protein tyrosine kinase 2
PTTG1IP pituitary tumor-transforming 1 interacting protein
PXDNL peroxidasin-like
RAI1 retinoic acid induced 1
RCC2 regulator of chromosome condensation 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF181 ring finger protein 181
RNF213 ring finger protein 213
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL17P39 ribosomal protein L17 pseudogene 39
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRBP1 ribosome binding protein 1
RSF1 remodeling and spacing factor 1
RTN4RL2 reticulon 4 receptor-like 2
RTP1 receptor (chemosensory) transporter protein 1
RTP2 receptor (chemosensory) transporter protein 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SACK1C scaffolding CK1 anchoring protein C
SASH1 SAM and SH3 domain containing 1
SBF2 SET binding factor 2
SCN3A sodium channel, voltage gated, type III alpha subunit
SECISBP2 SECIS binding protein 2
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans)
SERAC1 serine active site containing 1
SETD8 SET domain containing (lysine methyltransferase) 8
SFSWAP splicing factor, suppressor of white-apricot family
SGSM1 small G protein signaling modulator 1
SH2B1 SH2B adaptor protein 1
SH2D5 SH2 domain containing 5
SH2D6 SH2 domain containing 6
SHOX2 short stature homeobox 2
SI sucrase-isomaltase (alpha-glucosidase)
SKOR1 SKI family transcriptional corepressor 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC25A41 solute carrier family 25, member 41
SLC38A9 solute carrier family 38, member 9
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMAD4 SMAD family member 4
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMTN smoothelin
SNAP47 synaptosomal-associated protein, 47kDa
SNCAIP synuclein, alpha interacting protein
SNW1 SNW domain containing 1
SPATA13 spermatogenesis associated 13
SPATS2L spermatogenesis associated, serine-rich 2-like
SPEG SPEG complex locus
SPON2 spondin 2, extracellular matrix protein
SRCAP Snf2-related CREBBP activator protein
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAC SH3 and cysteine rich domain
STK11IP serine/threonine kinase 11 interacting protein
STK19 serine/threonine kinase 19
STXBP1 syntaxin binding protein 1
STXBP4 syntaxin binding protein 4
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TADA2A transcriptional adaptor 2A
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
TAOK2 TAO kinase 2
TBC1D10C TBC1 domain family, member 10C
TBCE tubulin folding cofactor E
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2
TCP11 t-complex 11, testis-specific
TDRD1 tudor domain containing 1
TDRD6 tudor domain containing 6
TECR trans-2,3-enoyl-CoA reductase
TENM1 teneurin transmembrane protein 1
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TEX14 testis expressed 14
THSD4 thrombospondin, type I, domain containing 4
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TKTL2 transketolase-like 2
TLR4 toll-like receptor 4
TMEM104 transmembrane protein 104
TMEM108 transmembrane protein 108
TMEM2 transmembrane protein 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TNS1 tensin 1
TOX2 TOX high mobility group box family member 2
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRIM40 tripartite motif containing 40
TRIO trio Rho guanine nucleotide exchange factor
TRIOBP TRIO and F-actin binding protein
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPT1 tRNA phosphotransferase 1
TSHB thyroid stimulating hormone, beta
TSPAN17 tetraspanin 17
TTC1 tetratricopeptide repeat domain 1
TTK TTK protein kinase
TTN titin
TTPAL tocopherol (alpha) transfer protein-like
UNC5D unc-5 homolog D (C. elegans)
UPK2 uroplakin 2
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP31 ubiquitin specific peptidase 31
VCAN versican
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WDR24 WD repeat domain 24
WDR49 WD repeat domain 49
WDR90 WD repeat domain 90
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNT2B wingless-type MMTV integration site family, member 2B
XIRP1 xin actin binding repeat containing 1
XPO5 exportin 5
YBX1 Y box binding protein 1
ZCCHC3 zinc finger, CCHC domain containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZFHX3 zinc finger homeobox 3
ZFHX4 zinc finger homeobox 4
ZNF12 zinc finger protein 12
ZNF155 zinc finger protein 155
ZNF177 zinc finger protein 177
ZNF233 zinc finger protein 233
ZNF256 zinc finger protein 256
ZNF268 zinc finger protein 268
ZNF385B zinc finger protein 385B
ZNF43 zinc finger protein 43
ZNF446 zinc finger protein 446
ZNF462 zinc finger protein 462
ZNF586 zinc finger protein 586
ZNF606 zinc finger protein 606
ZNF716 zinc finger protein 716
ZNF729 zinc finger protein 729
ZNF85 zinc finger protein 85
ZSWIM2 zinc finger, SWIM-type containing 2
ZSWIM4 zinc finger, SWIM-type containing 4