| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphoenolpyruvate carboxykinase 1 (soluble)|This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5105) |
| External Link | https://ncbi.nlm.nih.gov/gene/5105 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PCK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0185878 |
| TUBB2A | tubulin, beta 2A class IIa | 0.0138976 |
| TUBB2B | tubulin, beta 2B class IIb | 0.0136638 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0136481 |
| MELK | maternal embryonic leucine zipper kinase | 0.0129825 |
| ABLIM1 | actin binding LIM protein 1 | 0.0126893 |
| IL32 | interleukin 32 | 0.0120767 |
| SIRT3 | sirtuin 3 | 0.0113351 |
| NDRG1 | N-myc downstream regulated 1 | 0.0112417 |
| KRT14 | keratin 14, type I | 0.0107904 |
| LAMB3 | laminin, beta 3 | 0.0105256 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0103489 |
| XPO7 | exportin 7 | 0.0103306 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0102819 |
| YBX3 | Y box binding protein 3 | 0.0102634 |
| CCN3 | cellular communication network factor 3 | 0.0100472 |
| KRT1 | keratin 1, type II | 0.00990371 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00987473 |
| ACTB | actin, beta | 0.00978921 |
| PXDN | peroxidasin | 0.00971905 |
| FAM3C | family with sequence similarity 3, member C | 0.00970501 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00967863 |
| PLS3 | plastin 3 | 0.0096216 |
| KRT6A | keratin 6A, type II | 0.00951207 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00945183 |
| KRT16 | keratin 16, type I | 0.00921419 |
| SDC1 | syndecan 1 | 0.00912443 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00909806 |
| MEN1 | multiple endocrine neoplasia I | 0.00903593 |
| MIA | melanoma inhibitory activity | 0.00903115 |
| CALCA | calcitonin-related polypeptide alpha | 0.00894677 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00880875 |
| GRN | granulin | 0.00871417 |
| FGF9 | fibroblast growth factor 9 | 0.00868615 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00863151 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00862311 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0086098 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00860729 |
| HLA-B | major histocompatibility complex, class I, B | 0.00851637 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00850967 |
| ENAH | enabled homolog (Drosophila) | 0.00843957 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00840395 |
| KRT6B | keratin 6B, type II | 0.00837762 |
| MEOX2 | mesenchyme homeobox 2 | 0.00830034 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.00829061 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0082703 |
| VLDLR | very low density lipoprotein receptor | 0.0082472 |
| STK26 | serine/threonine protein kinase 26 | 0.00822689 |
| CALB1 | calbindin 1, 28kDa | 0.00820284 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00810327 |
| RUNX1 | runt-related transcription factor 1 | 0.00806833 |
| DSP | desmoplakin | 0.00804742 |
| NDRG4 | NDRG family member 4 | 0.00796768 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 0.00796404 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0079417 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0079307 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00792405 |
| INAVA | innate immunity activator | 0.00785903 |
| S100A10 | S100 calcium binding protein A10 | 0.00785804 |
| SPRR1B | small proline-rich protein 1B | 0.0078178 |
| PPL | periplakin | 0.00774037 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00770243 |
| PAM | peptidylglycine alpha-amidating monooxygenase | 0.00768183 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00766853 |
| PMM2 | phosphomannomutase 2 | 0.00762229 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00761117 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.00757958 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00757177 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.007562 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00752816 |
| PDZD2 | PDZ domain containing 2 | 0.00750462 |
| DBN1 | drebrin 1 | 0.00748818 |
| CD151 | CD151 molecule (Raph blood group) | 0.00747941 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00745556 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00744683 |
| GOLGA8H | golgin A8 family, member H | 0.00742763 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00738088 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00735554 |
| PRKCA | protein kinase C, alpha | 0.00735455 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00735265 |
| PON3 | paraoxonase 3 | 0.00735084 |
| KLF2 | Kruppel-like factor 2 | 0.00730924 |
| CDC37 | cell division cycle 37 | 0.00727332 |
| COL9A2 | collagen, type IX, alpha 2 | 0.00726437 |
| NES | nestin | 0.00723823 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00722843 |
| EPS8L2 | EPS8-like 2 | 0.00720803 |
| AIM2 | absent in melanoma 2 | 0.00720028 |
| LPIN1 | lipin 1 | 0.00716862 |
| RCAN1 | regulator of calcineurin 1 | 0.00716114 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00715456 |
| ALB | albumin | 0.0071305 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00711194 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.0071114 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.00710955 |
| ITGA6 | integrin, alpha 6 | 0.00710439 |
| THBS4 | thrombospondin 4 | 0.00710051 |
| KRT2 | keratin 2, type II | 0.00708181 |
| CALML3 | calmodulin-like 3 | 0.00705595 |
| VGLL4 | vestigial-like family member 4 | 0.00705526 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00699777 |
| GAL | galanin/GMAP prepropeptide | 0.00696978 |
| SLC22A18 | solute carrier family 22, member 18 | 0.00695221 |
| KLF6 | Kruppel-like factor 6 | 0.0069491 |
| SYBU | syntabulin (syntaxin-interacting) | 0.0069296 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00689785 |
| XIC | X chromosome inactivation center | 0.00688229 |
| HEATR1 | HEAT repeat containing 1 | 0.00687255 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | 0.00684307 |
| JAG2 | jagged 2 | 0.00681732 |
| COMP | cartilage oligomeric matrix protein | 0.00680745 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00679198 |
| LAD1 | ladinin 1 | 0.00678438 |
| PDGFD | platelet derived growth factor D | 0.00677271 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00677063 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00677053 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.00676107 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00673039 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00667032 |
| FOXO1 | forkhead box O1 | 0.00664988 |
| JUNB | jun B proto-oncogene | 0.00663851 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.00663527 |
| PRKD2 | protein kinase D2 | 0.00662247 |
| TNNC1 | troponin C type 1 (slow) | 0.00662192 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.00661081 |
| PSAP | prosaposin | 0.00660236 |
| PKP1 | plakophilin 1 | 0.00659972 |
| RTL8C | retrotransposon Gag like 8C | 0.00658393 |
| CD81 | CD81 molecule | 0.00657715 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00653897 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0065359 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00652164 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.0065102 |
| BCR | breakpoint cluster region | 0.00650355 |
| FZD5 | frizzled class receptor 5 | 0.00649011 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00647121 |
| USP18 | ubiquitin specific peptidase 18 | 0.00644676 |
| MVP | major vault protein | 0.00644363 |
| ABHD2 | abhydrolase domain containing 2 | 0.00643345 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.00643263 |
| PLD3 | phospholipase D family, member 3 | 0.00642998 |
| KRT5 | keratin 5, type II | 0.00639538 |
| NID1 | nidogen 1 | 0.00639103 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00638139 |
| MT1X | metallothionein 1X | 0.00638084 |
| USP11 | ubiquitin specific peptidase 11 | 0.00637893 |
| KLC1 | kinesin light chain 1 | 0.00637715 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0063752 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.006359 |
| CALML5 | calmodulin-like 5 | 0.00633778 |
| ANK2 | ankyrin 2, neuronal | 0.0063346 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase | 0.00632053 |
| PEG10 | paternally expressed 10 | 0.00632044 |
| FADS3 | fatty acid desaturase 3 | 0.00631116 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00631044 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00629832 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00626803 |
| FAM110B | family with sequence similarity 110, member B | 0.00626662 |
| S100A2 | S100 calcium binding protein A2 | 0.00626623 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.00626424 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00626412 |
| FARSA | phenylalanyl-tRNA synthetase, alpha subunit | 0.00625519 |
| TENM3 | teneurin transmembrane protein 3 | 0.00624639 |
| RASA4 | RAS p21 protein activator 4 | 0.00624592 |
| TRIM29 | tripartite motif containing 29 | 0.00622651 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00620706 |
| NKX2-1 | NK2 homeobox 1 | 0.00620649 |
| KLK5 | kallikrein-related peptidase 5 | 0.00620522 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00620063 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.00619961 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00619456 |
| NRN1 | neuritin 1 | 0.00618006 |
| MFAP5 | microfibrillar associated protein 5 | 0.00616959 |
| E2F2 | E2F transcription factor 2 | 0.00616648 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.006166 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00615801 |
| PLXNA1 | plexin A1 | 0.00612578 |
| F12 | coagulation factor XII (Hageman factor) | 0.0061252 |
| NOTCH3 | notch 3 | 0.00610861 |
| TARP | TCR gamma alternate reading frame protein | 0.00609625 |
| PTN | pleiotrophin | 0.00609286 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00608271 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00607528 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00606181 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | 0.00605984 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00602995 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.00600443 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00600049 |
| TCTA | T-cell leukemia translocation altered | 0.00599944 |
| KIAA0125 | KIAA0125 | 0.00599903 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00598605 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.00597094 |
| PCDH9 | protocadherin 9 | 0.005966 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00595103 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00594036 |
| GPR107 | G protein-coupled receptor 107 | 0.00592588 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.00592528 |
| RBM38 | RNA binding motif protein 38 | 0.00591242 |
| BMP2 | bone morphogenetic protein 2 | 0.00590724 |
| NBEAL2 | neurobeachin-like 2 | 0.00590391 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00590311 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00589554 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | 0.00587245 |
| MTMR11 | myotubularin related protein 11 | 0.00587025 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.005848 |
| FMO5 | flavin containing monooxygenase 5 | 0.00584551 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.00583587 |
| TCF3 | transcription factor 3 | 0.00583491 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00583461 |
| FGG | fibrinogen gamma chain | 0.00582442 |
| RNASET2 | ribonuclease T2 | 0.00581349 |
| CDO1 | cysteine dioxygenase type 1 | 0.00581019 |
| PITRM1 | pitrilysin metallopeptidase 1 | 0.00580381 |
| CLCA2 | chloride channel accessory 2 | 0.00579185 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00577751 |
| TCF4 | transcription factor 4 | 0.00577491 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00577426 |
| TAGLN2 | transgelin 2 | 0.00576755 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00576616 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00576075 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0057431 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00573187 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0057239 |
| BRD4 | bromodomain containing 4 | 0.00571667 |
| NRCAM | neuronal cell adhesion molecule | 0.00569746 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00569729 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.00569095 |
| CD99 | CD99 molecule | 0.0056905 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00568423 |
| OLFML2A | olfactomedin-like 2A | 0.00568257 |
| PUM3 | pumilio RNA binding family member 3 | 0.00567674 |
| JMJD6 | jumonji domain containing 6 | 0.00564488 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00564425 |
| SCRIB | scribbled planar cell polarity protein | 0.00564082 |
| EFNA5 | ephrin-A5 | 0.00562931 |
| UXS1 | UDP-glucuronate decarboxylase 1 | 0.00562762 |
| LECT1 | leukocyte cell derived chemotaxin 1 | 0.00562429 |
| PLXDC1 | plexin domain containing 1 | 0.0056199 |
| JMJD1C | jumonji domain containing 1C | 0.00561555 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00561094 |
| CYB561 | cytochrome b561 | 0.00559959 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00559761 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00558092 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00557494 |
| KIF13B | kinesin family member 13B | 0.00557203 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00556468 |
| ZNF512B | zinc finger protein 512B | 0.00553374 |
| EPHB4 | EPH receptor B4 | 0.00553186 |
| BIN3 | bridging integrator 3 | 0.00553019 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00552958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -0.0378636 |
| MSMB | microseminoprotein, beta- | -0.0160959 |
| SRGN | serglycin | -0.0153335 |
| LTF | lactotransferrin | -0.014778 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.0135778 |
| S100P | S100 calcium binding protein P | -0.0124295 |
| TFF1 | trefoil factor 1 | -0.012104 |
| AGR2 | anterior gradient 2 | -0.0120573 |
| TYMS | thymidylate synthetase | -0.0116284 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0114783 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.0113928 |
| EVI2A | ecotropic viral integration site 2A | -0.011364 |
| CDC42 | cell division cycle 42 | -0.0113511 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -0.0112348 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0112024 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0110301 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.0108825 |
| RGS10 | regulator of G-protein signaling 10 | -0.0107945 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.0107743 |
| FOXF1 | forkhead box F1 | -0.0105051 |
| OLFM1 | olfactomedin 1 | -0.0104647 |
| MAGEA3 | melanoma antigen family A3 | -0.0104055 |
| CCNE2 | cyclin E2 | -0.0103889 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.0103033 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0102105 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00996621 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0099389 |
| MKKS | McKusick-Kaufman syndrome | -0.00976584 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00965583 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00965452 |
| MLF1 | myeloid leukemia factor 1 | -0.00963711 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00960617 |
| ARL3 | ADP-ribosylation factor-like 3 | -0.00950326 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00946998 |
| RGS1 | regulator of G-protein signaling 1 | -0.00933607 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00920062 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | -0.00918189 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00913612 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00907025 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00905768 |
| MGAM | maltase-glucoamylase | -0.00898579 |
| PCLAF | PCNA clamp associated factor | -0.00896617 |
| RPA3 | replication protein A3, 14kDa | -0.00894432 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.00893993 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00886915 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00864043 |
| PANK2 | pantothenate kinase 2 | -0.0085847 |
| MLPH | melanophilin | -0.00858403 |
| NTS | neurotensin | -0.00857436 |
| GALC | galactosylceramidase | -0.00855131 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00853142 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00848995 |
| RIN2 | Ras and Rab interactor 2 | -0.00846138 |
| CHN2 | chimerin 2 | -0.00844489 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00842828 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00841447 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00839088 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00837976 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00836641 |
| NNMT | nicotinamide N-methyltransferase | -0.00835223 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -0.00834828 |
| AURKA | aurora kinase A | -0.0083365 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00832409 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | -0.00818728 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00803442 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | -0.00800207 |
| SNX5 | sorting nexin 5 | -0.00800138 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00798048 |
| CLC | Charcot-Leyden crystal galectin | -0.00792736 |
| MAGEB2 | melanoma antigen family B2 | -0.00790549 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00781203 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 | -0.00780033 |
| UPK1B | uroplakin 1B | -0.00779471 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00778997 |
| PLCB4 | phospholipase C, beta 4 | -0.00777663 |
| OLFM4 | olfactomedin 4 | -0.00776565 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00775527 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00774382 |
| ARMT1 | acidic residue methyltransferase 1 | -0.0077395 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00773181 |
| ASRGL1 | asparaginase like 1 | -0.00767666 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00767112 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00763062 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00762525 |
| TMEM230 | transmembrane protein 230 | -0.00759875 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -0.00758384 |
| NME5 | NME/NM23 family member 5 | -0.00756275 |
| CLDN10 | claudin 10 | -0.00752531 |
| PDZK1 | PDZ domain containing 1 | -0.00751696 |
| TEX30 | testis expressed 30 | -0.0075146 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00750083 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00749859 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00749137 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | -0.0074814 |
| TOB1 | transducer of ERBB2, 1 | -0.00747678 |
| ANXA3 | annexin A3 | -0.00747186 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00744088 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00744045 |
| NUP50 | nucleoporin 50kDa | -0.00742295 |
| ADIRF | adipogenesis regulatory factor | -0.00740098 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00739392 |
| MAOB | monoamine oxidase B | -0.00736967 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.00732726 |
| RPS27L | ribosomal protein S27-like | -0.00730731 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.00730218 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.0072684 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | -0.00725569 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.00723174 |
| GCK | glucokinase (hexokinase 4) | -0.00719601 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00718813 |
| STOM | stomatin | -0.00715096 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00714129 |
| CMC2 | C-x(9)-C motif containing 2 | -0.00714068 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00707894 |
| MPC1 | mitochondrial pyruvate carrier 1 | -0.0070714 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00699376 |
| NDUFA6 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | -0.0069824 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00695646 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00693077 |
| MMD | monocyte to macrophage differentiation-associated | -0.00692836 |
| SLC16A4 | solute carrier family 16, member 4 | -0.0069198 |
| CEP43 | centrosomal protein 43 | -0.00691333 |
| COBL | cordon-bleu WH2 repeat protein | -0.006885 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -0.0068825 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.0068757 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.00686812 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00686537 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00685492 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00683986 |
| MEIS2 | Meis homeobox 2 | -0.00682497 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00680485 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.00679386 |
| COPS4 | COP9 signalosome subunit 4 | -0.0067836 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00677607 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.00677462 |
| KIF20A | kinesin family member 20A | -0.00676606 |
| BICC1 | BicC family RNA binding protein 1 | -0.00676267 |
| H2AZ1 | H2A.Z variant histone 1 | -0.00676102 |
| LYZ | lysozyme | -0.00675935 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00674826 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00671938 |
| LSM1 | LSM1, U6 small nuclear RNA associated | -0.00668265 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.00667972 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00667946 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00667161 |
| CD48 | CD48 molecule | -0.00666342 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00665527 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | -0.0066485 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00664209 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00662968 |
| CAMP | cathelicidin antimicrobial peptide | -0.00662858 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00662399 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00661195 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00660685 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00659062 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00658515 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00657854 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00655492 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.00654995 |
| TTC33 | tetratricopeptide repeat domain 33 | -0.00654781 |
| PLSCR1 | phospholipid scramblase 1 | -0.00654634 |
| CCND2 | cyclin D2 | -0.00653673 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00652498 |
| USP22 | ubiquitin specific peptidase 22 | -0.00651852 |
| MPO | myeloperoxidase | -0.006511 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | -0.00649095 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.00648068 |
| PLIN2 | perilipin 2 | -0.00647548 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00646599 |
| CREM | cAMP responsive element modulator | -0.00645967 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00643138 |
| NEK2 | NIMA-related kinase 2 | -0.00642474 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00642174 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00641921 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | -0.00641461 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.00640052 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00639641 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.0063964 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.00638913 |
| HMGB2 | high mobility group box 2 | -0.00638713 |
| ATF1 | activating transcription factor 1 | -0.0063784 |
| INSIG1 | insulin induced gene 1 | -0.00636943 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.0063682 |
| IL1R1 | interleukin 1 receptor, type I | -0.0063526 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00635101 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00634633 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00633136 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.00630583 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00629933 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00629615 |
| BPI | bactericidal/permeability-increasing protein | -0.00627705 |
| PMP22 | peripheral myelin protein 22 | -0.00627028 |
| LRRC6 | leucine rich repeat containing 6 | -0.00623828 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00623193 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00622522 |
| APOC1 | apolipoprotein C-I | -0.00618171 |
| IL6ST | interleukin 6 signal transducer | -0.00618112 |
| SPA17 | sperm autoantigenic protein 17 | -0.00617995 |
| NANS | N-acetylneuraminic acid synthase | -0.00617717 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0061673 |
| MRPL48 | mitochondrial ribosomal protein L48 | -0.00615474 |
| C21ORF91 | chromosome 21 open reading frame 91 | -0.00613545 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00613288 |
| PRR4 | proline rich 4 (lacrimal) | -0.00610685 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | -0.00608933 |
| NSFL1C | NSFL1 (p97) cofactor (p47) | -0.00608296 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.00607577 |
| RGS2 | regulator of G-protein signaling 2 | -0.00607043 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00603555 |
| TJP3 | tight junction protein 3 | -0.00603044 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00602975 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00602247 |
| BCL2A1 | BCL2-related protein A1 | -0.00602164 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -0.00601518 |
| ABHD10 | abhydrolase domain containing 10 | -0.00600397 |
| TBPL1 | TBP-like 1 | -0.00600256 |
| H2AFV | H2A histone family, member V | -0.00599921 |
| MYRF | myelin regulatory factor | -0.00599529 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | -0.00599521 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00596153 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00595902 |
| ATG3 | autophagy related 3 | -0.00595881 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | -0.00592272 |
| CRTC3 | CREB regulated transcription coactivator 3 | -0.00592257 |
| TKTL1 | transketolase-like 1 | -0.00591744 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00591038 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | -0.0059054 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00590432 |
| ESR1 | estrogen receptor 1 | -0.00589501 |
| IFI44 | interferon-induced protein 44 | -0.00588912 |
| CRIPT | cysteine-rich PDZ-binding protein | -0.0058826 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.00587619 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00587268 |
| HCRT | hypocretin (orexin) neuropeptide precursor | -0.00587105 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00586741 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00586176 |
| SRPRB | signal recognition particle receptor, B subunit | -0.00585527 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00584589 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00584239 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00582763 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog | -0.00582132 |
| MSH2 | mutS homolog 2 | -0.00582001 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00581479 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00580737 |
| IFT46 | intraflagellar transport 46 | -0.00580599 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00579871 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.00579626 |
| CD300A | CD300a molecule | -0.00579403 |
| TBX3 | T-box 3 | -0.00579163 |
