PCK1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description phosphoenolpyruvate carboxykinase 1 (soluble)|This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5105)
External Link http://www.ncbi.nlm.nih.gov/gene/5105
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Genes

74 interacting proteins for PCK1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ACTB actin, beta
APP amyloid beta (A4) precursor protein
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BAG6 BCL2-associated athanogene 6
BSG basigin (Ok blood group)
C1QBP complement component 1, q subcomponent binding protein
C1R complement component 1, r subcomponent
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CPT1A carnitine palmitoyltransferase 1A (liver)
CUL5 cullin 5
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EP300 E1A binding protein p300
FAF2 Fas associated factor family member 2
FASN fatty acid synthase
FBXO25 F-box protein 25
GIGYF2 GRB10 interacting GYF protein 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAS GNAS complex locus
GPHN gephyrin
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HSPA1L heat shock 70kDa protein 1-like
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRS4 insulin receptor substrate 4
LDHA lactate dehydrogenase A
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MYLK2 myosin light chain kinase 2
NUP62 nucleoporin 62kDa
ONECUT1 one cut homeobox 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
RPL10L ribosomal protein L10-like
RPL14 ribosomal protein L14
RPL23 ribosomal protein L23
RPL4 ribosomal protein L4
RPLP0 ribosomal protein, large, P0
RPS15A ribosomal protein S15a
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS6 ribosomal protein S6
SIRT2 sirtuin 2
SKP1 S-phase kinase-associated protein 1
SQSTM1 sequestosome 1
SRPRB signal recognition particle receptor, B subunit
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TCP1 t-complex 1
TSC22D3 TSC22 domain family, member 3
UBC ubiquitin C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP11 ubiquitin specific peptidase 11
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta